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Medicine

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Alzheimer's, Amyloid, clinical trial, New England Journal

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 24-Jan-2018 5:00 PM EST

Medicine

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Opioid, Opioids, Telemedicine, Medical Marijuana, Medicine, Regulation, medical board, state medical boards, Physician

FSMB Survey: Opioid Prescribing, Telemedicine among Most Important Regulatory Topics for State Medical Boards

The Federation of State Medical Boards (FSMB) announced that resources related to opioid prescribing and telemedicine are currently the most important regulatory issues to state medical boards. The announcement comes after analyzing responses from 51 state medical boards as part of the FSMB’s 2017 annual survey to its member boards.

Life

Law and Public Policy

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Johns Hopkins Carey Business School, Life Science Professionals, Life Science, Pharamcuetical Science, Pharmaceucticals, business accelerator

Reluctance to Share Innovations with Peer Firms Means Lost Opportunities for Life Sciences Companies

Professor Phillip Phan of the Johns Hopkins Carey Business School says the reluctance by life sciences companies to share information with sector peers reduces potential innovations and benefits.

Medicine

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Drug Discovery, Big Data, Protein, Computational Biology, Pharmacuetical, Pharmacy, Enzyme

New Research Could Significantly Accelerate Drug Discovery

Many drugs work by inhibiting protein enzymes associated with a particular disease. Unfortunately, the same drugs can inhibit protein enzymes unrelated to the disease, resulting in harmful side effects. A team of computational biologist has developed a way to identify the features that distinguish one enzyme from similar enzymes. This research has the potential to significantly accelerate drug discovery, allowing scientists to develop more effective drugs, more quickly.

Medicine

Science

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Drug Discovery, Drug Development, High-throughput screening, CD73 inhibitors, multiplex RF-MSMS Assay, immuno-oncology, laboratory automation

A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

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A new original research article in SLAS Discovery presents a fast, sensitive, and robust methodology for screening small molecule inhibitors against CD73/Ecto-5’-Nucleotidase, a promising target for developing anti-cancer drugs.

Medicine

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Stroke, Ischemic Stroke, tPA, Tpa Treatment, Door to Needle Time, Pharmacists, pharmacists and stroke, RTPA, Tissue Plasminogen Activator, recombinant tissue plasminogen activator

Having a Pharmacist at Stroke Patient's Bedside Speeds Administration of Critical Drug

In treating stroke patients, every minute counts. A drug called rtPA sometimes can stop a stroke in its tracks. Now a Loyola Medicine study has found that having a pharmacist at the patient's bedside can reduce the time it takes to administer rtPA by a median of 23.5 minutes.

Medicine

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american association for clinical chemistry, Aacc, Laboratory Medicine, Drug Testing, laboratory testing, urine drug testing, Opioid Epidemic, opioid overdoses , Opioid Addiction, pre

AACC Releases Practice Guidelines for Using Laboratory Drug Tests to Combat Opioid Addiction, Overdoses

WASHINGTON – AACC has issued a new guideline detailing how healthcare providers can use laboratory tests to manage treatment of pain and prevent prescription drug overdoses. Especially relevant in light of the worsening opioid epidemic, the guideline emphasizes increased collaboration between clinicians and laboratory experts as well as the use of more precise drug tests as key to identifying pain patients who are abusing their opioid prescriptions.

Science

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Biology, fish, Contaminants, Wastewater, Pharmaceuticals, Metabolism, Sewage

Pharmaceuticals and Other Emerging Contaminants Force Fish to Work Harder to Survive

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Pharmaceuticals and other man-made contaminants are forcing fish that live downstream from a typical sewage treatment plant to work at least 30 per cent harder just to survive, McMaster researchers have found.

Medicine

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High Cholesterol, cholesterol management, Penn Medicine, perelman school of medicine , Health Insurance, Prescription Drug Benefit, Cardiology, Cardiovascular Medicine, PCSK9 Inhibitors, Cardiovascular Quality

Insurance Company Requirements Place Heavy Administrative Burden on Physicians Seeking to Prescribe New Cholesterol-Lowering Drugs

A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke. So-called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are self-injected medications approved for individuals with a genetic condition called familial hypercholesterolemia (FH) and those with atherosclerotic cardiovascular disease (ASCVD) who have high cholesterol despite receiving traditional statin medications and other treatments. Results of the study are published in Circulation: Cardiovascular Quality and Outcomes.

Medicine

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Open Access, Publication, Journal, digital medicine, Translational Medicine, Health, Education, data, Medicine

Scripps Translational Science Institute, Nature Research Launch Open-Access Digital Medicine Journal

Researchers from the Scripps Translational Science Institute (STSI) at The Scripps Research Institute (TSRI) have launched an open-access, peer-reviewed online journal—npj Digital Medicine.







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