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Medicine

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opioid abuse, Opioid Abuse Epidemic, Opioid Addiction, Public Health, pre

Two New Online Medical Education Courses Address Opioid Crisis

The DC Center for Rational Prescribing (DCRx) today announced the availability of two new online education courses aimed at teaching doctors and other healthcare professionals some of the myths and facts surrounding the use of prescription opioid painkillers. The information in the online videos could help curb the epidemic of opioid-related deaths by reducing unnecessary prescriptions—and offers valuable advice on how to wean patients from these addictive drugs.

Science

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Epilelpsy, Drug Discovery, Anticonvulsant, Electroshock, Seizures, Neuroscience, Neurological Disorder, C.Elegans

The ‘Worm’ Holds the Key to Treating Epilepsy; New Possibilities for Rapid Drug Discovery

Current methods to control epilepsy are not only inefficient but haven’t improved in more than 150 years when the first anticonvulsant drug was developed. Researchers have opened up the possibilities for rapid drug screens to treat seizures in the near future by developing the smallest whole-animal electroconvulsive seizure model using a microscopic nematode worm.

Medicine

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Hepatitis, Hepatitis B, Hepatitis B research, Hepatitis B Virus, hepatitis B virus (HBV), pharmacological research, Pharmacology, Pharmacologic, pharmacologic compound, pharmacology and therapeutics, Drug Research, Drug Research and Development

NIH Grants MU $3 Million to Develop New Hepatitis B Treatments

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Hepatitis B (HBV) is a viral infection that increases the likelihood of developing liver cancer or liver failure. According to the World Health Organization, an estimated 2 billion people currently are infected with HBV, which is more than 10 times the number of people who have human immunodeficiency virus (HIV). Currently, treatment for hepatitis B infections is limited to one class of drugs that targets the virus. Stefan Sarafianos, an investigator with the University of Missouri Bond Life Sciences Center (BLSC) recently was awarded $3 million from the National Institutes of Health to study the disease. Building on existing research, he and his team will work on the development of new drugs to treat HBV.

Medicine

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Vanderbilt, zinc, Supplements, Dietary Supplements, Clostridium Difficile, Eric Skaar, Nature Medicine

Excess Dietary Zinc Worsens C. Diff Infection

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The findings, reported Sept. 26 in Nature Medicine, call into question the consumption of dietary supplements and cold therapies containing high concentrations of zinc.

Medicine

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Antibiotic Resistance, Urgent care center, antibiotic overuse, Superbugs, Antbiotic over prescribing

Urgent Care Association of America and the Antibiotic Resistance Action Center Form Partnership to Address Antibiotic Use in Rapidly Growing Urgent Care Sector

The Urgent Care Association of America (UCAOA) and the Antibiotic Resistance Action Center (ARAC) at the Milken Institute School of Public Health at George Washington University announced today that they are entering into a three-year partnership to make the urgent care industry a leader in antibiotic stewardship by reducing inappropriate antibiotic use in this outpatient setting — action that could help slow the growing threat of antibiotic resistance.

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Inside the Lab: Using Botox to Advance Science

Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.

Medicine

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Penn Medicine, opioid abuse, Opioid Abuse Epidemic, Prescription Drug Abuse, oral surgery, wisdom teeth

100 Million Prescription Opioids Go Unused Each Year Following Wisdom Teeth Removal, Penn Study Estimates

More than half of opioids prescribed to patients following surgical tooth extraction – such as the removal of impacted wisdom teeth – were left unused by patients in a new study from researchers at the University of Pennsylvania’s Perelman School of Medicine and School of Dental Medicine. The authors say the surplus is troubling given the ongoing opioid epidemic and evidence showing that individuals who abuse prescription opioids often use leftover pills that were prescribed for friends or family members.

Medicine

Science

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Virginia Tech, ACS Chemical Biology, Fungus, Aspergillus Fumigatus, Drug Discovery, Virginia Tech Center for Drug Discovery

Researchers Find Fungus-Fighting Compound in Drug Discovery Center Library

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Researchers with the Virginia Tech Center for Drug Discovery have identified a compound that blocks the growth of a fungus that causes deadly lung infections and allergic reactions in people with compromised immune systems.

Science

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skin, skin stretchiness, Burn Victims, burn, human skin, skin growth, Tissue, body tissue, Binghamton University, SUNY Binghamton, State University of New York at Binghamton, skin grafting, skin grafts, Topical Drugs, Schick, stratum corneum

Researchers Stretch Understanding of Skin’s Limits

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New techniques could help surgeons optimize tissue expansion procedures to maximize skin growth rates

Medicine

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drug deliver, Tumor, Cancer, magnetic bacteria

Swarms of Magnetic Bacteria Could Be Used to Deliver Drugs to Tumors

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Researchers have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs.

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Drug Restores Hair Growth in Patients with Alopecia Areata

Seventy-five percent of patients with an autoimmune disease that causes hair loss had significant hair regrowth after treatment with ruxolitinib, according to a study from Columbia University Medical Center.

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First Practical Guidelines for Research Antibody Validation Are the Goal at Scientific Workshop Hosted by GBSI Sept 25-27

Scientific Community to Tackle Reproducibility Standards in Antibody Research

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Bile Acid Uptake Inhibitor Prevents NASH/Fatty Liver in Mice

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children’s Healthcare of Atlanta have shown. The findings suggest that these drugs, known as ASBT inhibitors, could be a viable clinical strategy to address NASH, an increasingly common liver disease. The results are scheduled for publication in Science Translational Medicine on September 21, 2016.

Science

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Neuroscience, Biochemistry, monobodies, pharmaceutical development, Molecular Biophysics, Neurodevelopment

Researchers Describe Key Protein Structure and a Drug Prototype That Could Assist Therapeutic Development

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Researchers from the University of Chicago have described the three-dimensional, atomic structure of an important cell receptor molecule linked to the development of several diseases.

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Law and Public Policy

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Presidential Debate: Expert Panel Gives Scientific Analysis of Candidates' Performances

Four expert panelists each day will present their analyses and answer your questions live and face-to-face. This event will be virtual. You can attend with any device -- PC, Mac, iPad, iPhone or Android device (with a webcam) – anywhere with good bandwidth. To participate (ask questions) in the meeting, you must be on video, just as a normal news conference. Register below for guaranteed seating; there is limited seating in the virtual room. Eight experts (four at each event) will present their analyses. The diverse expert team (7 universities and an institute) will analyze both candidates during the debates for their gestures, facial expressions (including smiles--number, type, appropriateness, etc.), posture, language, including sentiment, tone, inflammatory language, repetition, vocabulary, sentence structure, metaphors, framing, themes, suggestions, subtlety, nuance, honesty (deceit/lies—explicit and implicit), transparency, gender issues, and more...

Medicine

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Research, Science, Health, Anesthesiology

American Society of Anesthesiologists Hosts ANESTHESIOLOGY® 2016

From novel procedures to treat chronic pain to new research that may help treat Alzheimer’s disease, ANESTHESIOLOGY® 2016 is the premier gathering in the field, showcasing the cutting-edge research taking place in this medical specialty that serves millions of patients undergoing operations, procedures and tackling pain every year.

Science

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Cell Division, Pharmacology, Cancer

Scientists Discover Interplay of Yin-Yang Antagonists Vital for Cell Division

UNC School of Medicine scientists discover that a pair of large enzyme complexes attack each other in turn to form a molecular switch, which is essential for cell division.

Medicine

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Breast Cancer, Cancer Biomarkers, Genomics, cancer disparities, cancer drug resistance, cancer drug development

UCSF Researchers Awarded Breast Cancer Research Funding From Susan G. Komen

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Three UCSF researchers have been awarded $680,000 in grants from Susan G. Komen to support projects in breast cancer research. The grants to UCSF were among a total of $32.7 million given to researchers in 23 states and seven countries for projects including research into metastatic disease, novel treatments for aggressive types of breast cancer, new technologies, and health equity.

Medicine

Science

Business

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GBSI, Antibody Validation, Antibody, Antibodies, irreproducibility, Irreproducible, Reproducibility, Freedman, Leonard Freedman, Leonard P. Freedman, PhD, Global Biological Standards Institute , Asilomar

GBSI’s Workshop Gathers 100+ Biomedical Research Experts at Asilomar to Develop the First Practical, Implementable Antibody Validation Guidelines

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Global Biological Standards Institute (GBSI) gathers 100+ biomedical research experts from around the world next week at the scientifically historic Asilomar Conference Grounds in California for a workshop to discuss, define and vote on the first detailed standardized guidelines for validating research antibodies. Antibody Validation: Standards, Policies, and Practices will build upon the conceptual framework published September 5, in Nature Methods, in order to establish practical, applicable and implementable antibody validation guidelines. A webcast press briefing will present broad consensus-based outcomes September 28. Follow along on Twitter with #AbValidate.

Medicine

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Chronic Pain, Opioids, Dr. W. Michael Hooten, Dr. Michael Camilleri, Pain Medication, news release

Opioid Crisis: Video with Mayo Experts Available for Media

ROCHESTER, Minn. — Each day, 78 people in the U.S. die of opioid overdoses, and more than 1,000 are treated in emergency departments for opioid misuse, federal figures show. In a series of broadcast-quality, 60-second videos available for media use, Mayo Clinic anesthesiologist and pain medicine expert W. Michael Hooten, M.D., and gastroenterologist Michael Camilleri, M.D., discuss the opioid epidemic and the dangers associated with inappropriate use of prescription pain medication.







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