Cancer Expert Dr. Mikkael Sekeres Endorses FDA Approval of New Drug, Imetelstat
Sylvester Comprehensive Cancer Center
Radyus Research partners with Southern Research for an innovative alliance in the development of new drugs.
An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.
In a new study, Sanford Burnham Prebys researchers, led by Andrei L. Osterman, Ph.D., combined experimental evolution in a continuous culturing device with whole genome sequencing of evolving cultures to track how two bacterial pathogens acquired drug resistance against a pair of antibiotics, one long-used and the other experimental.
Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues. UTSW received another $6 million for recruitment efforts.
New research shows HIV medications can be taken at the same time as hormone treatment without losing potency of either therapy.
Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.
The eyes have been called the window to the brain. It turns out they also serve as an immunological barrier that protects the organ from pathogens and even tumors, Yale researchers have found.
The FDA has approved two medications for the treatment of eosinophilic esophagitis (EoE)—the first oral medication tailored for adults and the exclusive therapeutic option for children. Evan Dellon, MD, MPH, internationally known for his work with EoE, and colleagues continue to focus on optimizing usage for effective, personalized outcomes.
Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.
Bridging precision engineering and precision medicine to create personalized physiology avatars. Pursuing on-demand tissue and organ engineering for human health. Revolutionizing neuroscience by using AI to engineer advanced brain interface systems. Engineering the immune system for health and wellness. Designing and engineering genomes for organism repurposing and genomic perturbations.
A subpopulation of gut bacteria given a commonly used antibiotic became "persisters" that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered. Their findings, published in Cell Host & Microbe, could lead to better ways to fight bacterial infections.
Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.
Digital Science is pleased to announce that ReadCube, an award-winning leader in literature management and full-text document delivery, has launched a new solution for research-driven organizations – known simply as Literature Review by ReadCube.
RUDN University doctors demonstrated the capabilities of a new method for remote analysis of drugs in packaging and after entering the body. They can be assessed using radio thermal emission of nanoparticles in drugs. Scientists were able to check the suitability of the medicine without opening the packaging or monitor it inside the body.
Calls to U.S. poison centers involving psilocybin, or “magic mushrooms,” among adolescents and young adults rose sharply after several U.S. cities and states began decriminalizing the hallucinogen, University of Virginia School of Medicine researchers have found.
To provide a clear picture of opioid manufacture and travel, the University of Notre Dame developed a user-friendly interface to enable public access to more than 10 years of national controlled substance transaction information. This platform makes querying easier and faster, providing transactional data on 14 different opioids including fentanyl, hydrocodone and oxycodone.
Diabetic patients who take anti-diabetic drugs - known as glitazones – long term had a lower risk of primary and secondary brain cancer compared with diabetic patients on other medications, new research led by the University of Bristol has found.
Results of 16-Center REVIVE trial published in The New England Journal of Medicine
Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.
An online pharmacy offering standardized, transparent pricing can reduce out-of-pocket costs for patients taking common medications prescribed by urologists, suggests a study in the March issue of Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
RUDN University doctors collected statistics on cases of extreme drug allergies - anaphylaxis. The authors presented the results in different age groups and named the most dangerous drugs for an allergic reaction.
RUDN University pharmacists modeled derivative molecules of the antibacterial levofloxacin to find out what biological functions its individual structural fragments - pharmacophores - are responsible for. This is necessary to increase the effectiveness of the drug, as bacteria become increasingly resistant to antibiotics.
Drugs for treating osteoporosis can be expensive and have side effects. In the search for alternative drug candidates, researchers reporting in ACS Central Science have discovered and fully replicated a compound from female ginseng that had potent anti-osteoporotic activity in cellular tests.
A four-drug chemotherapy regimen of irinotecan liposome (Onivyde) in combination with oxaliplatin, leucovorin, and fluorouracil has been approved by the FDA for the first-line treatment of metastatic pancreatic adenocarcinoma.
New drug inspired by images that captured how bacteria block antibiotic activity
The in silico trial demonstrated 2X the efficacy of the current treatment (>80% vs 39%); 3X shorter treatment time to cure (6 vs 18 months); 1 drug compared to a 3-drug combo for the standard of care; and preclinical results in shorter time than animal models.
Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.
Saint Louis University’s Liz Chiarello, Ph.D., associate professor of sociology recently published an article in the American Sociological Review, the flagship journal of the American Sociological Association. The article explores pharmacists’ use of prescription drug monitoring programs (PDMPs) and the ethical and practical application of PDMPs in healthcare.
Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.
The UCLA team played a pivotal role in a clinical trial that led to the FDA granting accelerated approval of the first antibody drug conjugate (ADC), mirvetuximab soravtansine, for the treatment of platinum-resistant ovarian cancer.
MD Anderso and C-Biomex today announced a strategic collaboration to co-develop CBT-001, a radioligand targeting the CA9 cancer biomarker.
No increased risks for babies, and for some serious neonatal complications lower risks.
Analysis from Rutgers Health and Harvard links first-trimester methadone use with a greater risk of various birth defects than buprenorphine use.
The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life.
For 21 years, nurses have consistently been the most trusted profession, according to the yearly Gallup poll. (The new poll will be issued by the end of January). Dr Rushton, who specializes in burnout, will speak on trust, moral injury, and how nurses cope in this day and age.
The American Society of Anesthesiologists (ASA) commends the Centers for Medicare & Medicaid Services (CMS) for taking positive steps towards returning balance to the independent dispute resolution (IDR) process of the No Surprises Act (NSA) through a recently proposed rule.
Treatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body’s immune system, an effect that is difficult to deliver with currently available pharmaceuticals, a new Yale study finds.
Northwestern University researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.
Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.
The University of Texas MD Anderson Cancer Center today announced the signing of an agreement with the International Atomic Energy Agency (IAEA) to become an IAEA Collaborating Centre.
A study led by University of California, Irvine researchers has revealed a connection between blood levels of omega-3 and the inflammatory biomarker interleukin-8 and greater chemotherapy-related gastrointestinal symptoms in breast cancer patients.