Fear never works. Or does it? Fear can be a powerful tool in public health efforts, although graphic, emotionally evocative campaigns have been the source of controversy over the past half-century.
New research from the University of Georgia suggests that in the case of HPV, health care providers shouldn’t place too much faith in the smart device alone to get their message across.
Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. However, scientists know little about the early stages of the condition. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC Santa Barbara have discovered that host responses during sepsis progression can vary in important ways based on pathogen type—which could lead to more effective treatments. The study published today in Cell Host and Microbe.
A novel synthetic DNA vaccine developed based on technology pioneered by Wistar scientists offers complete protection from Zaire Ebolavirus (EBOV) infection in promising preclinical research.
Researchers at the UNC School of Medicine have been awarded a 5-year, $3.8 million grant from the National Institute of Allergy and Infectious Diseases to develop next generation, ultra-long-acting antiretroviral formulations for HIV treatment and prevention that have the potential to dramatically improve adherence.
A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers.
Washington University School of Medicine in St. Louis led a national study of 2,400 first-time pregnant women. The research showed that the timing of pushing has no effect on whether women deliver vaginally or by C-section.
Although hot water and bubble baths may sound relaxing to many, for those with atopic dermatitis, this can have the opposite effect, causing dry, scaly, red patches to develop on the skin. Affecting nearly 28 million Americans, atopic dermatitis, also known as eczema, is frequently described as the “itch that rashes.” Since the condition makes it harder for the skin to keep out harmful bacteria, viruses and other germs, people with eczema often have sensitive skin prone to inflammation and infections. Although there is no cure for eczema, dermatologists from the American Academy of Dermatology say those with moderate to severe eczema can improve their symptoms and reduce their risk of skin infections using bleach bath therapy.
MANHATTAN — African swine fever virus threatens to devastate the swine industry and is positioned to spread throughout Asia. The virus has spread throughout the Caucuses region of Eastern Europe and was reported in China in August. It recently was detected in wild boar in Belgium.Kansas State University researchers and the Biosecurity Research Institute have several projects focused on African swine fever.
Rutgers researchers have discovered a new system to deliver antimicrobial agents -- drugs, antiseptics or pesticides -- that could more effectively treat or prevent bacterial infections.
For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans. This unique approach — in which immunized humans transfer anti-malarial proteins to mosquitoes when bitten — is called a transmission-blocking vaccine (TBV). A new biotech advancement moves us closer to this goal. If successful, it could help reduce the spread of the disease, which kills more than 400,000 people annually.
Currently, a once-daily pill to prevent HIV infection is available. However, adherence to a once-daily regimen can be difficult for some people. Researchers from the UNC School of Medicine and the Centers for Disease Control and Prevention published a study today in Nature Communications that reports a potentially promising remedy for this problem.
A team of nurses and physicians has received a four-year, $3 million grant from the National Heart, Lung, and Blood Institute to extend traditional HIV treatment protocols to improve the cardiovascular health of people living with HIV.
Researchers have successfully incorporated “photosensitizers” into a range of polymers, giving those materials the ability to render bacteria and viruses inactive using only ambient oxygen and visible-wavelength light.
Scientists at Scripps Research have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful listeria and staph infections.
The University of Illinois at Chicago is one of eight universities awarded funding by the National Institutes of Health to prevent and treat sexually transmitted infections, including HIV, among adolescents and young adults in Africa and Brazil. Collectively, the international projects are known as Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H).
Wistar scientists and collaborators demonstrate for the first time that through engineering constructs, they can express DNA-encoded monoclonal antibodies (DMAbs) targeting CTLA-4, an important cancer checkpoint molecule that blocks anti-cancer immunity.
Wenquan Zou, MD, PhD, and his collaborator, Qingzhong Kong, PhD, of Case Western Reserve University School of Medicine, have been awarded $2.9M from the National Institutes of Health to extend their previous path-breaking finding of skin prions of these devastating diseases.
Antibiotic resistance is an urgent problem globally when treating many infections. Now a team of scientists believe a better understanding of the mechanisms of pili, the hair-like surface appendages on bacteria that initiate infection, could hold a key to developing new and more effective therapeutics.
Peter Wiklund, MD, PhD, a world-renowned surgeon who pioneered robot-assisted cystectomy, has been appointed Director of the Bladder Cancer Program at the Mount Sinai Health System and Professor of Urology in the Department of Urology at the Icahn School of Medicine at Mount Sinai.
A new National Institutes of Health (NIH) High-Risk, High-Reward grant will allow Penn State’s Dr. Steven Schiff and team to explore a radically changed approach to predicting, preventing and treating infectious disease at the individual level at point-of-care.
Runny noses are annoying and easy to dismiss. And that’s exactly why one doctor waited so long to seek medical attention. Now, he realizes that mistake could have cost him his eyesight, or even his life.
A new study from the NYU College of Global Public Health and NYU Tandon School of Engineering, published in Nature Digital Medicine, used text message surveys to determine in real time how people used maternal health services during a recent Ebola outbreak and measured a drop in hospital-based births during the outbreak.
When patients present to providers in North Carolina for a possible tick bite, clinicians are not testing them for Ehrlichia, a tick-borne illness that occurs more frequently than Lyme disease and as frequently as Rocky Mountain Spotted Fever.
Efthimios Parasidis, associate professor of law and public health at The Ohio State University, talks about whether or not it's a good idea for companies to mandate that their employees get a flu shot.
Status of House Bill 193: https://www.legislature.ohio.gov/legislation/legislation-status?id=GA132-HB-193
Chris M. Gonzalez, MD, MBA, FACS, has been named the Albert J. Jr. and Claire R. Speh professor and chair of the department of urology of Loyola Medicine and Loyola University Chicago Stritch School of Medicine.
Drinking an additional 1.5 liters of water daily can reduce recurring bladder infections in premenopausal women by nearly half, a yearlong study of otherwise healthy women with a history of repeated infections has found.
In a new study published in the Journal of Biological Chemistry, researchers at Imperial College London and the Francis Crick Institute report some of the details of how Salmonella shuts down an immune pathway after infection.
A quantitative proteomic study of how influenza virus affects lung-derived cell lines found that protein synthesis machinery relocates to the autophagosome in infected cells.
Loyola University Chicago and Loyola Medicine have announced plans to become the first Chicago center to produce cancer-fighting CAR-T cells to treat leukemia and lymphoma. Loyola plans to produce a more purified CAR-T cell that could reduce toxicities and costs.
A low-cost, easy-to-replicate test for tuberculosis might help developing nations better identify and treat the infectious and sometimes deadly disease, new research suggests.
In the quest to develop a vaccine that triggers the immune system to prevent HIV infection, researchers have focused on identifying and eliciting a particular type of antibody that is capable of neutralizing the virus.
A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.
In low-resource countries without well-developed screening programs, expanding access to human papilloma virus (HPV) vaccination is the best means of preventing cervical cancer and other diseases caused by HPV infection, according to an editorial in the October special issue of the Journal of Lower Genital Tract Disease, official journal of ASCCP. The journal is published in the Lippincott portfolio by Wolters Kluwer.
To rapidly detect the presence of E. coli in drinking water, Cornell University food scientists now can employ a bacteriophage – a genetically engineered virus – in a test used in hard-to-reach areas around the world.
Scientists have known that bacteria produce small spherical versions of themselves. Lacking basic materials to function like normal cells, the role of minicells has remained a mystery. Now, researchers at UC San Diego have demonstrated for the first time that minicells play a key function in the survival of bacteria.
Diabetes makes it harder for the immune system to fight off some infections, leaving people with the condition at a higher risk for serious complications from vaccine-preventable diseases, like the flu, pneumonia, hepatitis B, tetanus and shingles.
In a study publishing September 26 in Science Advances, researchers at University of California San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that tweaking factors in a cystic fibrosis lung model, such as pH balance and oxygen, helped eradicate pathogenic bacteria while minimizing risks of antibiotic resistance and overgrowth of other microorganisms.
A new Philadelphia-based start-up, Virion Therapeutics, LLC spun out of The Wistar Institute, will work to advance innovative, immune-based therapies for the treatment of chronic viral-associated cancers and viral infections utilizing the first genetically encoded checkpoint inhibitor that can be given via vaccination.
CU Boulder researchers have identified a family of small molecules that turn off defense mechanisms inside bacteria that enable them to resist antibiotics. The compounds could ultimately be given alongside existing medications to rejuvenate them.