A new study published in Nature provides clues that could enhance physicians’ ability to pinpoint, in real-time, which patients are not responding to therapy – and intervene with additional drugs to boost the chances of shrinking tumors.
The researchers report that low-dose penicillin taken late in pregnancy and in early life of mice offspring, changes behaviour and the balance of microbes in the gut. While these studies have been performed in mice, they point to popular increasing concerns about the long-term effects of antibiotics.
A natural, or bioidentical, combined estradiol-progesterone capsule (TX-001HR) significantly decreases the frequency and severity of moderate to severe hot flashes in postmenopausal women, the Replenish study finds. Results of this phase 3, randomized, placebo-controlled, multicenter trial will be presented Monday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.
Johns Hopkins researchers say that the findings they published in the current edition of The American Journal of Gastroenterology could have important implications for the field of personalized medicine.
Chemists have designed triple-threat cancer-fighting polymer capsules for guided drug delivery. They combine three traits: good imaging contrast with low-power ultrasound, stable packaging of the cancer drug doxorubicin, and ability to trigger drug release with low- or higher-power ultrasound.
Scientists from the Fred Hutchinson Cancer Research Center in Seattle are scheduled to present and discuss the latest developments in immunotherapy and proteomics at the American Association for Cancer Research Annual Meeting, Research Propelling Cancer Prevention and Cures, on April 1-5. What follows is a selection of the more than 30 Hutch presentations at the AACR gathering
Researchers at Baylor Scott & White Research Institute identified a new genetic biomarker for colon cancer that may lead to development of more targeted treatment of the disease
Collaborative study with Cleveland Clinic & SUNY Upstate Medical University shows that single high-dose SBRT treatment is as effective as three doses in patients with non-small cell lung cancer
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.
A summary of a select abstracts by Dana-Farber researchers being presented at 2017 AACR Annual Meeting in April
Proteins shake their bodies and wave their limbs — essentially dancing — all with the goal of optimizing their interaction with other molecules, including other proteins. A new study shows that, in biological courtship, dance moves matter. The findings help to lay a foundation for the development of drugs targeting molecular vibrations. Such pharmaceuticals would block proteins from carrying out tasks that contribute to disease.
In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010–2012. A perspective in AACC’s Clinical Chemistry journal discusses the project’s preliminary results and suggests changes the research community can make to prevent reproducibility issues from inhibiting cancer care.
The patient ingests a capsule containing two miniature cameras on either end. As the capsule travels through the digestive tract, it captures images and wirelessly transmits them to a recorder the patient wears on a belt.
More than 87,000 chemicals are available commercially in the U.S., including analogues of bisphenol A (BPA), an industrial chemical that is used in consumer products. Frederick vom Saal, a University of Missouri endocrinologist and researcher, has studied BPA and other chemicals and their effects on humans and animals for more than 20 years. Now, vom Saal has released Integrative Environmental Medicine, a comprehensive book outlining practical resources and tools, such as websites and smartphone apps, to help health care practitioners promote healthier choices for themselves and their patients.
The press program for next week’s 2017 Multidisciplinary Thoracic Cancers Symposium features research advances in lung cancer including immunotherapy, proton therapy and liquid biopsy, among others.
A new intervention developed by Bar-Ilan University scientists to tamper with parasites' communication system may lead to the development of drugs to treat, and prevent the spread of, devastating diseases such as African sleeping sickness, leishmaniasis and Chagas' disease.
Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.
A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.
Computer model shows what happens at the molecular level during severe allergic reactions to abacavir, a common HIV drug
A preliminary study suggests that a new, wireless patch that you wear on your arm may help reduce migraine pain as well as drugs. The study is published in the March 1, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.
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