A widely found gene in plants has been newly identified as a key transporter of a hormone that influences the size of corn. The discovery offers plant breeders a new tool to develop desirable dwarf varieties that could enhance the crop’s resilience and profitability.
Scientists at St. Jude Children’s Research Hospital designed an intersectional technique for precisely targeting subpopulations of cells and parsing out specific functions.
UC San Diego Assistant Professor of Physics Mattia Serra and colleagues at Politecnico di Milano (Italy) have developed a new method that can manipulate the movement of embryonic cells using short-time attractors — a concept Serra had previously developed and adopted to help search and rescue operations at sea.
Scientists at St. Jude Children’s Research Hospital reveal the role of iRhom2’s defunct protein-cleaving domain in lifecycle of ADAM17, a key signaling molecule-activating protein.
Dr. Hyuk-June Moon from the Bionics Research Center at the Korea Institute of Science and Technology (KIST), in collaboration with Prof. Olaf Blanke’s team at the Swiss Federal Institute of Technology Lausanne (EPFL), has successfully induced self-location illusions with multi-sensory virtual reality (VR) in the MRI scanner and observed corresponding changes in the human brain's grid cell activity.
Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings, recently published in Circulation, could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.
Researchers from the University of Chicago show that a drug molecule targeting RNA modifications in neuroblastoma cells suppresses tumor growth in mice.
Understanding how mucus changes, and what it changes in response to, can help diagnose illnesses and develop treatments. In APL Bioengineering, researchers develop a system to grow mucus-producing intestinal cells and study the characteristics of the mucus in different conditions.
Researchers from the Gene Therapy Program (GTP) at the Perelman School of Medicine at the University of Pennsylvania will present ten research abstracts, two invited talks, and a workshop presentation highlighting their translational science and discovery research on gene therapy, gene editing, and adeno-associated virus (AAV) vector technology at the American Society of Cell and Gene Therapy (ASGCT) 27th Annual Meeting on May 7 - 11, 2024 in Baltimore, Maryland.
• Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily activity of skin and muscles. • The coordination between the two clocks (central and peripheral) guarantees 50% of the circadian functions of tissues, including vital processes such as the cell cycle, DNA repair, mitochondrial activity, and metabolism. • Synchronisation between the central brain clock and peripheral ones prevents premature muscle ageing and improves muscle function, suggesting new strategies to tackle age-related decline through circadian rhythm modulation.
This method is a major leap forward for scientists investigating how proteins do their jobs in the immune system. “This method basically creates an entire new kind of world of experiments that people can do..."
Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals’ lifespan.
Miriam Merad, MD, PhD, a world-renowned immunologist, has been appointed Dean for Translational Research and Therapeutic Innovation of the Icahn School of Medicine at Mount Sinai. The appointment reaffirms Icahn Mount Sinai’s commitment to pioneering medical progress and catalyzing the rapid advancement of research innovation. Dr. Merad, the Mount Sinai Professor in Cancer Immunology, will also continue to serve as the founding Chair of the Department of Immunology and Immunotherapy, Director of the Marc and Jennifer Lipschultz Precision Immunology Institute, and Director of the Human Immune Monitoring Center. As Dean, Dr. Merad aims to elevate early clinical trials at Icahn Mount Sinai, streamline the clinical trial process, cultivate a culture of mechanistic clinical trials throughout the campus, and forge stronger partnerships with the pharmaceutical and biotech sectors.
By transplanting human neural stem cells, researchers improved memory and reduced neuroinflammation in a mouse model of Alzheimer’s Disease, suggesting another avenue for potential treatment, a study shows. Researchers say the improvements reported after stem cell transplantation must be further studied in mice before advancing to larger animals and, eventually, humans.
Three researchers from the Johns Hopkins University School of Medicine have been elected to the American Association for the Advancement of Science’s (AAAS) class of 2023 fellows.
CellFE Inc., a life sciences tools company with a novel microfluidics-based cellular engineering platform, announced today an upcoming presentation by CSO Todd Sulchek, PhD, at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting, taking place May 7-11, 2024 in Baltimore, MD.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe. Named Naegleriavirus, these belong to the giant viruses, a group known for their unusually large particles and complex genomes.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
