Feature Channels: Aging

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Remote UC San Diego School of Medicine study finds brain function boosted by daily exercise in middle-aged and older adults.

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A strong majority of American adults over 50 -- including the 37% of older adults who own guns or live with someone who does -- supports specific steps that could reduce the risk of firearm injury and death, a new national study shows. The study also highlights opportunities to help older adults recognize and address the risks in their own homes.

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Here are some of the latest articles we've posted in the Behavioral Science channel.

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In Physics of Fluids, engineers from China use fluid dynamics simulations to study the effect of exercise at various ages on plaque formation in the arteries. The authors considered two arterial geometries, one with a bulging outer artery and the other without, and modeled the effect of exercise and age on blood flow. To model exercise, the authors digitized blood flow measurements from individuals in three age groups and used these flowrates as input to their computational model.

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Women ages 35 years and younger were 44% more likely to have an ischemic stroke (caused by blocked blood vessels in the brain) than their male counterparts, according to a new review of more than a dozen international studies on sex differences in stroke occurrence, published today in a Go Red for Women® 2022 spotlight issue of Stroke, a peer-reviewed journal of the American Stroke Association, a division of the American Heart Association.

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The latest research news from the Health Disparities Channel.

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UC San Diego Herbert Wertheim School of Public Health study reports that the more steps taken, and the more intense, the lower the risk of Type 2 diabetes among women 65 and older.

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Chula Medicine has successfully invented RED-GEMs (REjuvenating DNA by GEnomic Stability Molecules) that can reverse aging in lab animals. With human trials targeted within two years, the medical breakthrough is aimed to treat various age-related conditions and illnesses and bring back youthfulness in this aging society.

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Research at the Baudry Lab at The University of Alabama in Huntsville (UAH) to model how the SETBP1 protein interacts with other DNA to regulate a cell has attracted one of 40 global $46,000 seed grants from the Million-Dollar Bike Ride program at the University of Pennsylvania Health System.

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亲爱的妙佑医疗国际(Mayo Clinic)：随着年龄的增长，医生给我开的药越来越多，比如血压和胆固醇的药物。另外，随着年龄的增长，我服用了一些用来提高记忆力、降低胆固醇和预防癌症的补充剂。我是否应该担心这些补充剂会与我的药物产生相互作用？

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ESTIMADA MAYO CLINIC: A medida que envejezco, los médicos me recetan más medicamentos, por ejemplo, para la presión arterial y el colesterol. Además, según me voy haciendo mayor, he decidido tomar suplementos que supuestamente mejoran la memoria, reducen el colesterol y previenen el cáncer.

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ESTIMADA MAYO CLINIC: conforme fui envelhecendo, os médicos passaram a me prescrever mais medicamentos para o controle da pressão sanguínea e colesterol, por exemplo.

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A new study finds that while young and healthy mice show clear differences between daytime and nighttime body temperature rhythms, in older and diseased animals the difference essentially disappeared.

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Higher levels of antioxidants – particularly manganese antioxidants – could potentially extend one’s lifespan and radiation resistance, according to a new study published on Jan. 11 in mBio by researchers at the Uniformed Services University of the Health Sciences (USU).

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A medicina regenerativa poderia retardar a evolução das doenças degenerativas que frequentemente devastam os anos da maturidade, revela um estudo da Mayo Clinic. A expectativa de vida quase dobrou desde os anos 50, mas a expectativa de saúde (o número de anos sem doenças) não acompanhou o ritmo. De acordo com um artigo publicado na revista NPJ Regenerative Medicine, de maneira geral, as pessoas vivem mais tempo, mas a última década de vida é frequentemente assolada por doenças crônicas relacionadas ao envelhecimento, o que diminui a qualidade de vida. Esses últimos anos de vida vêm com uma grande sobrecarga de custos para a sociedade.

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La medicina regenerativa puede lentificar el reloj de aquellas enfermedades degenerativas que suelen causar estragos durante la tercera edad, descubre un estudio de Mayo Clinic. La expectativa de vida casi se ha duplicado desde la década de los años 50; pero la expectativa de salud, que son los años sin sufrir enfermedades, se ha mantenido al mismo ritmo. Según un trabajo publicado en NPJ Regenerative Medicine (Medicina Regenerativa de NPJ), las personas suelen vivir más largo, pero en su última década de vida generalmente se ven aquejadas por aquellas enfermedades crónicas y propias de la edad que disminuyen la calidad de vida. Además, esos últimos años representan una gran carga para la sociedad.

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退行性疾病的到来通常意味着老年黄金岁月遭受破坏，但妙佑医疗国际(Mayo Clinic)的一项研究发现，再生医学可以减缓退行性疾病的发展。自1950年代以来，人类的寿命几乎翻番，但无病痛的健康寿命却没有同步跟上。根据发表在《NPJ 再生醫學》（NPJ Regenerative Medicine）上的一篇论文，人的寿命普遍有所增长，但在最后的十年里，往往会饱受与年龄相关的慢性疾病的困扰，这些疾病降低了生活质量。人在最后几年的时光往往会给社会带来巨大的成本负担。

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When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

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Complimentary press passes are now available for the Experimental Biology (EB) 2022 meeting, to be held April 2–5 in Philadelphia. EB is the annual meeting of five scientific societies bringing together thousands of scientists and 25 guest societies in one interdisciplinary community.

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January, National Glaucoma Awareness Month, is an excellent time to get a comprehensive dilated eye exam—the most effective way to test for glaucoma—and to convince your loved ones to get tested, too.

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January, National Glaucoma Awareness Month, is an excellent time to focus on eye health.

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The Association for Research in Vision and Ophthalmology (ARVO) today announced Joanne Wood, PhD, is the 2022 recipient of the Oberdorfer Award in Low Vision Research. Wood's body of research has made a significant contribution to health practice and policy, including advice to licensing bodies and health professionals regarding driver licensing standards, and has been translated into standards.

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What if the key to aging well lies in reprogramming immune system cells to strengthen them against infections and cancer? Researchers at UT Southwestern are working to find out.

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Investigators at Cedars-Sinai have identified growth hormone in the colon that increases as the colon ages—a discovery that can help guide the development of a new anti-aging therapy.

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The American Academy of Orthopaedic Surgeons (AAOS) issued an update to the Clinical Practice Guideline (CPG) for Management of Hip Fractures in Older Adults (age 55 years and older), replacing the 1st edition released in 2014, which initially covered a patient population of 65 years and older.

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Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists. The scientists, from the National Eye Institute (NEI), part of the National Institutes of Health, published their findings today in Nature Communications.

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The brain is a battlefield where cognitive domains vie for limited resources, and this appears to be particularly true during sleep.

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For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer’s disease treatment.

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Using artificial intelligence, a team of University at Buffalo researchers has developed a novel system that models the progression of chronic diseases as patients age.

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A new study finds that a simple, self-administered test developed by researchers at The Ohio State University Wexner Medical Center, College of Medicine and College of Public Health can identify the early, subtle signs of dementia sooner than the most commonly used office-based standard cognitive test.

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In this study of 3,000 adults with cataracts, the risk of developing dementia was lower in participants who underwent cataract removal compared with those who didn’t.

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Researchers report that an abbreviated, seven-item scale can help determine with high validity a person’s level of wisdom, a potentially modifiable personality trait that has been shown to have a strong association to well-being.

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During pandemic-induced isolation, researchers from the University of Minnesota surveyed older adults with vision loss, with hearing loss, or without either condition, asking the participants about their worries, well-being, and social isolation at six-week intervals. All three groups scored lower on a patient health questionnaire after the pandemic began; however, people with vision or hearing loss faced unique problems in lockdown. Disruptions to mobility systems affected people with low vision, and masks made conversations especially difficult for adults with hearing loss.

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Difficulty in understanding speech, especially in background noise, is a common concern for older adults. Using a word identification task in quiet and noisy conditions, researchers examined the impact of mild dementia on speech perception. They tested individuals with and without mild dementia and found that word identification scores of those without dementia were significantly better in all conditions, meaning people with mild dementia symptoms recalled fewer words in both quiet and noisy situations.

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USC study published in the Journal of Experimental Medicine shows that experimental drug protects against injury caused by tiny blood clots in the brain’s white matter, which can accumulate over time and lead to cognitive decline

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Researchers used telephone and web survey data to examine how health-related factors and social determinants such as income and social participation, impacted the prevalence of depressive symptoms during the initial lockdown starting March 2020 and after re-opening following the first wave of COVID-19 in Canada. Caregiving responsibilities, separation from family, family conflict, and loneliness were associated with a greater likelihood of moderate or high levels of depressive symptoms that got worse over time.

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Black Americans 65 years and older have much better hearing than their White counterparts, according to a recent study published in the Journal of Speech, Language, and Hearing Research.

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A new study led by researchers at UCLA Health has found that cognitive behavioral therapy (CBT-I) prevented major depression, decreasing the likelihood of depression by over 50% as compared to sleep education therapy in adults over the age of 60 with insomnia.

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Trips, slips and falls are a major cause of injury, hospitalization and death in older people, and the pandemic may have increased their risk. Prevention can start with quick fixes in their homes that can be made during a holiday visit.

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Press conferences at the 181st Meeting of the Acoustical Society of America will be held Wednesday, Dec. 1, in room 505 at the Hyatt Regency Seattle. The media availabilities will focus on wide range of newsworthy sessions at the upcoming meeting from killer whales spending more time in the Arctic Ocean to knocking over Lego minifigures with time reversal focused vibration. For more information, contact AIP Media.