Torrance Memorial Medical Center, a Cedars-Sinai affiliate, recently broke ground on the new Hunt Cancer Center. The center, a collaboration with Cedars-Sinai, will provide its patients with access to subspecialists who treat more than 60 types of common, rare and complex cancers.
A new way to examine stress and inflammation in the heart will help Parkinson’s researchers test new therapies and explore an unappreciated way the disease puts people at risk of falls and hospitalization.
In a new study, a team led by clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) surveyed family members and patients with recent ICU experiences about their willingness to speak up about care concerns to medical providers.
• Compared with warfarin use, direct oral anticoagulant use was linked with a 23% higher risk of bleeding in patients with chronic kidney disease. • There was no difference between direct oral anticoagulant and warfarin users in benefits from prevention of ischemic stroke.
Athletes who have attention deficit hyperactivity disorder (ADHD) may be at greater risk for experiencing persistent anxiety and depression after a concussion than people who do not have ADHD, according to a preliminary study released today that will be presented at the American Academy of Neurology’s Sports Concussion Conference in Indianapolis, July 20 to 22, 2018. ADHD is a brain disorder that affects attention and behavior.
An international team of scientists has found the first evidence of a source of high-energy cosmic neutrinos, subatomic particles that can emerge from their sources and, like cosmological ghosts, pass through the universe unscathed, traveling for billions of light years from the most extreme environments in the universe to Earth.
A new study out of Beth Israel Deaconess Medical Center reveals that the preventability of readmissions changes over time: readmissions within the first week after discharge are often preventable by the hospital, whereas readmissions later are often related to patients’ difficultly accessing outpatient clinics.
By some estimates, 18 million people die each year from sepsis triggered by endotoxins – fragments of the outer membranes of bacteria. A biochemical engineer at Missouri University of Science and Technology has patented a method of removing these harmful elements from water and also from pharmaceutical formulations.Her goal: improve drug safety and increase access to clean drinking water in the developing world.
More than 16,000 ticks were sent in by people across the country and tested for various bacterial infections. Results show ticks capable of carrying Lyme disease are more widespread than originally thought.
New research has uncovered a protein enabling the replication of arenaviruses, lethal pathogens spreading in West Africa. The research identified DDX3 as a key factor through its unexpected ability to dismantle normal human immune system defenses. The study may pave the way to new therapeutic treatments for arenaviruses and hemorrhagic fever.
A stable cell line of Wolbachia-infected fruit fly cells turned out to be an invaluable tool for researchers seeking new drugs to treat river blindness and related diseases. That's because the parasitic worms that cause these diseases are actually dependent on Wolbachia bacteria living within their cells. Kill the Wolbachia, and the worms die.
Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted during Lou Gehrig’s, the new study suggests supplementing it could be a novel therapeutic approach for the disease.
Among Medicaid recipients taking prescription opioids, high opioid doses and concurrent treatment with benzodiazepine sedatives are among the key, potentially modifiable risk factors for fatal overdose, reports a study in the August issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Travel by airplane has opened the door to experiencing different cultures and exploring natural wonders. That is, if you can get past the jet lag. But what if you could take control of the brain's daily timing system? Biologists at Washington University in St. Louis unlocked a cure for jet lag in mice by activating a small subset of the neurons involved in setting daily rhythms, as reported in a July 12 advance online publication of Neuron.
A single, ghostly subatomic particle that traveled some 4 billion light-years before reaching Earth has helped astronomers pinpoint a likely source of high-energy cosmic rays for the first time. Subsequent observations with the National Science Foundation’s (NSF) Karl G. Jansky Very Large Array (VLA) have given the scientists some tantalizing clues about how such energetic cosmic rays may be formed at the cores of distant galaxies.
Involvement in veterans service organizations an lower post traumatic stress and can lower the stigma of accessing medical care, according to new research from an American University professor.
In areas of the country disproportionately affected by the opioid crisis, treatment programs are less likely to accept patients paying through insurance of any type or accept pregnant women, a new Vanderbilt study found.
In this Q&A, Berkeley Lab physicist Spencer Klein, who has been a part of the IceCube collaboration since 2004, discusses Berkeley Lab's historic contributions to IceCube, and IceCube's contributions to science.
A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology. “This simple blood test demonstrates the potential of biomarker-based risk assessment to improve eligibility criteria for lung cancer screening with low-dose computed tomography,” said study co-senior author Sam Hanash, M.D., Ph.D., professor of Clinical Cancer Prevention at The University of Texas MD Anderson Cancer Center.
UCLA researchers have found that the PGC-1α gene, previously known to control human metabolism, also controls the equilibrium of bone and fat in bone marrow and also how an adult stem cell expresses its final cell type. The findings could lead to a better understanding of the disruption of bone-to-fat ratio in bone marrow and its health consequences, and point to the gene as a therapeutic target in the treatment of osteoporosis and skeletal aging.
A multi-hospital collaboration led by researchers at Children’s Hospital of Philadelphia (CHOP) has found a simple method of determining which premature infants should be screened for retinopathy of prematurity (ROP).
Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology The variations explain why the human protein is more precise and more selective than mammalian forms of the protein and why it targets certain types of DNA but ignores others The findings can inform the design of more precisely targeted immune therapies against cancer and a range of immune-mediated diseases
Star-shaped gold nanoparticles, coated with a semiconductor, can produce hydrogen from water over four times more efficiently than other methods – opening the door to improved storage of solar energy and other advances that could boost renewable energy use and combat climate change, according to Rutgers University–New Brunswick researchers.
A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer.
A team of University of Iowa researchers built a web-based app called MapTrek. When synced with a Fitbit, MapTrek allows users to go on virtual walking tours of locations such as the Grand Canyon or Appalachian trail while competing against other users. A study showed MapTrek and Fitbit users averaged 2,200 more steps per day than a control group that used only Fitbits.
Using the Hubble and Gaia space observatories, astronomers have made the most precise measurements to date of the expansion of space, which may suggest reworking our understanding of the physics of the universe.
In a “proof of concept” study, scientists at Johns Hopkins Medicine say they have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice. The contents of the super-small containers were designed to target cancer stem cells, a kind of cellular “seed” that produces countless progeny and is a relentless barrier to ridding the brain of malignant cells.
A review of more than 200 studies reveals that olfactory receptors—proteins that bind to odors that aid the sense of smell—perform a wide range of mostly unknown functions outside the nose. The function of extra-nasal olfactory receptors has the potential to be used in the diagnosis and treatment of health conditions such as cancer.
Sea-level rise will endanger valuable salt marshes across the United Kingdom by 2100 if greenhouse gas emissions continue unabated, according to an international study co-authored by a Rutgers University–New Brunswick professor.
A new study from a team of researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania School of Nursing (Penn Nursing) found that in the previous three months, about half of parents talked on a cell phone while driving when their children between the ages of 4 and 10 were in the car, while one in three read text messages and one in seven used social media.
Alzheimer’s disease is a progressive, neurodegenerative condition that often begins with mild cognitive impairment (MCI), making early and repeated assessments of cognitive change crucial to diagnosis and treatment. In a paper in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, researchers led by scientists at the University of California San Diego School of Medicine found that repeated testing of middle-age men produced a “practice effect” which obscured true cognitive decline and delayed detection of MCI.
Older people who have higher blood pressure may have more signs of brain disease, specifically brain lesions, according to a study published in the July 11, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers also found a link between higher blood pressure and more markers of Alzheimer’s disease, tangles in the brain.
Researchers investigated whether the location of the mutation within the sequence of the PIK3CA gene affected the mutation’s ability to help drive glioblastoma growth. They also tested whether mutations within certain sequences of the gene were linked to better responses to particular drugs. They found mutational status was not linked to a response to a single targeted drug, but it was to a combination of treatments.
Enjoying full-fat milk, yogurt, cheese and butter is unlikely to send people to an early grave, according to new research by The University of Texas Health Science Center at Houston (UTHealth).
If a hepatitis C vaccine were successfully developed, it would dramatically reduce transmission of hepatitis C among drug users. even if the vaccine did not provide complete immunity, according to a study published in Science Translational Medicine.
Violence that occurs between intimate partners does not end with the relationship’s conclusion, yet few resources exist to help survivors move beyond the betrayal of abusive relationships in order to begin new, healthy relationships. The effects of intimate partner violence (IPV) are profound, painfully enduring and should command as much attention as providing victims with the help necessary to leave violent relationships, according to a new study by a University at Buffalo social work researcher.
Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65
Commercial insurance medical policies that do not cover treatment with proton therapy can make it difficult for patients to participate in randomized clinical trials funded by the NCI, part of the National Institutes of Health, that are evaluating the therapy.
The compound urea is currently the most popular nitrogen soil fertilizer. It’s a way to get plants the nitrogen they need to grow. There’s just one problem with urease: it works too well! New research suggests farmers may have a choice in how they slow the release of nitrogen, depending on their soil’s acidity.
Robotic surgery is as effective as traditional open surgery in treating bladder cancer, according to a landmark study published in the journal Lancet.
A tiny fern – with each leaf the size of a gnat – may provide global impact for sinking atmospheric carbon dioxide, fixing nitrogen in agriculture and shooing pesky insects from crops. The fern’s full genome has been sequenced by a Cornell University and Boyce Thompson Institute (BTI) scientist and his colleagues around the world, as reported in the journal Nature Plants.
Support from female co-workers may be even more important to new moms who are breastfeeding than getting encouragement from their significant others, close friends and relatives, says a new study. According to Michigan State University and Texas Christian University researchers, the more support women receive from their colleagues, the more successful they are in believing they can continue breastfeeding.
A clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI® (durvalumab) for advanced ovarian and colorectal cancers has been initiated.
The gains in insurance coverage with the Patient Protection and Affordable Care Act (ACA) have already translated into improved health for young women with gynecologic cancers, who are getting diagnosed at earlier stages of their disease because of ACA benefits. That’s the conclusion of a new study by researchers at Johns Hopkins Medicine, who looked at nationwide trends in gynecologic cancer diagnosis in a large population of women before and after the ACA’s implementation in 2010.
College students entering adulthood often drink too much. Negative consequences can include missed classes, poor grades, a wide array of injuries, and even assault. Many academic institutions have addressed this problem by offering computer-delivered interventions (CDIs) for rapid and wide dissemination to students. Although effective in the short term, CDIs are not as helpful longer-term as face-to-face interventions. However, face-to-face interventions are typically only used with students who receive alcohol sanctions, whereas CDIs can be used with large groups (such as student athletes, or all incoming students) and are more cost-effective. This study examined the usefulness of “boosters” – personalized emails sent to post-CDI participants– for maintaining decreased drinking.
A new study helps illuminate the ways in which a composer might intentionally impart sadness into the lines of an orchestral piece. Here’s a clue: It doesn’t take much. The solo player proves to be an important element of the kind of songs that tighten our throats and leave us searching for a tissue mid-performance, found a study led by Niels Chr. Hansen of The Ohio State University.
Advanced algorithms working from large chemical databases can predict a new chemical’s toxicity better than standard animal tests, suggests a study led by scientists at Johns Hopkins Bloomberg School of Public Health.
Adam Friedman, MD, professor of dermatology at the GW School of Medicine and Health Sciences, and his team investigated the use of nanotechnology to improve efinaconazole treatment and make it more cost effective.
A study finds that chemicals used in flame retardants, plasticizers and other commercial products are broken down through the process of metabolism into other compounds. Researchers say not enough is known about the dangers posed by those compounds, known as metabolites.
Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
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