High value chemicals used to make pharmaceuticals could be made much cheaper and quicker thanks to a series of new catalysts made by scientists at the University of Warwick in collaboration with GoldenKeys High-Tech Co., Ltd. in China.
Critical care nurses may be less likely to experience moral distress when they feel that patients’ palliative care needs are being met, according to results of a survey of ICU nurses at the University of Virginia Medical Center.
Most people over 50 aren’t ready to embrace virtual health visits with their medical providers, a new poll on telehealth finds. Only 4% have had a video-based visit with a provider in the past year, and their reactions were mixed. Meanwhile, more than half of poll respondents didn’t know if their providers offer telehealth visits, and more than 80% expressed at least one concern about seeing a doctor or other provider virtually.
A panel of international scientists led by researchers at Dalhousie and McMaster universities systematically reviewed the evidence and have recommended that most adults should continue to eat their current levels of red and processed meat.
Nearly one in three low-income people who enrolled in Michigan’s expanded Medicaid program discovered they had a chronic illness that had never been diagnosed before, according to a new study. And whether it was a newly found condition or one they’d known about before, half of Medicaid expansion enrollees with chronic conditions said their overall health improved after one year of coverage or more.
For young people, being the victim of violence can lead to risky sexual behavior.
Studies show measurable adverse biologic effects on lung health and cells in humans, in animals, and in tissue samples studied in the lab. The effects of e-cigarettes have similarities to those seen in traditional cigarettes and important differences
Common herbs, including lavender, fennel and chamomile, have a long history of use as folk medicines used to lower blood pressure. In a new study, University of California, Irvine researchers explain the molecular mechanisms that make them work.
Das Pankreasadenokarzinom (PDAC) ist ein letales Malignom, das am häufigsten gegen eine Chemotherapie resistent ist. Forscher haben nach Möglichkeiten gesucht, die Anfälligkeit der Tumore für krebsbekämpfende Medikamente zu erhöhen.
L'adénocarcinome du pancréas (PDAC) est une tumeur maligne mortelle qui résiste le plus souvent à la chimiothérapie. Les chercheurs ont cherché des moyens d'accroître la sensibilité des tumeurs aux médicaments anticancéreux.
A program developed to encourage healthy relationships and reduce dating violence was effective among early middle school students, according to results of a study published in the American Journal of Public Health by researchers at The University of Texas Health Science Center at Houston (UTHealth).
روشستر مينيسوتا — عندما يلزم إجراء عملية أخرى لمريض الترقيع التحويلي للشريان التاجي (CABG) بسبب تكرار حدوث ألم في الصدر، يتم ذلك في أكثر الأحيان بالتدخل التاجي عن طريق الجلد (PCI)، والمعروف بشكل عام باسم رأب الأوعية التاجية مع الدعامات.
Quando um paciente submetido a uma cirurgia de revascularização do miocárdio precisa de uma segunda cirurgia devido à recorrência de dores no peito, é muito comum a realização de uma Intervenção Coronária Percutânea (ICP), também conhecida como angioplastia coronária com stents.
Black women in America often feel pressured to act like Superwoman to cope with the stress of race- and gender-based discrimination in their daily lives, which can have health implications, according to a new study co-led by a Michigan State University researcher. The Superwoman persona refers to the idea of feeling a need to be strong, self-sacrificing and emotionless, said Yijie Wang, assistant professor of human development and family studies.
يُعد اعتلال الغدة الكظرية للقناة البنكرياسية (PDAC) ورمًا خبيثًا قاتلاً وغالبًا ما يقاوم العلاج الكيميائي. يفتش الباحثون عن طرق لزيادة حساسية الأورام للعقاقير المضادة للسرطان.
Lorsqu'un patient qui a subi un pontage aorto-coronarien (PAC) nécessite une deuxième intervention chirurgicale en raison d'une douleur thoracique récurrente, le plus souvent il s'agit d'une intervention coronarienne percutanée (IPC), communément appelée angioplastie coronarienne, avec des stents.
胰腺癌(PDAC)是一种致命的恶性肿瘤，通常对化疗具有抗药性。研究人员一直在寻找提高肿瘤对抗癌药物的敏感性的方法。Mayo Clinic今日发布的一项自主研究成果在抗癌战役中开辟了一条新战线。
O adenocarcinoma pancreático (ACDP) é um carcinoma letal geralmente resistente à quimioterapia. Os pesquisadores têm buscado formas de aumentar a sensibilidade dos tumores aos medicamentos de combate ao câncer.
Wenn ein Koronararterien-Bypass-(CABG)-Patient wegen wiederholter Schmerzen im Brustkorb eine zweite Operation braucht, ist dies häufig eine perkutane Koronarintervention (PCI), gemeinhin als Koronarangioplastie mit Stents bekannt.
Research published in the Journal of Forensic Sciences claiming to identify the notorious 19th century murderer through DNA analysis grabbed headlines around the world in the spring of 2019.
The study shows that for those participants who do not have a history of heart disease or stroke that a simple cardiac risk score – a summary measure of factors such as blood pressure, diabetes, smoking, abdominal fat, and dietary factors – is associated with MRI-detected pre-clinical cerebrovascular disease like carotid artery plaque and silent strokes.
Rising ocean temperatures have long been linked to negative impacts for marine life, but a Florida State University team has found that the long-term outlook for many marine species is much more complex — and possibly bleaker — than scientists previously believed.FSU doctoral student Jennifer McHenry, Assistant Professor of Geography Sarah Lester and collaborators with the National Oceanic and Atmospheric Administration (NOAA) investigated how marine species’ habitats are likely to be affected by multiple factors associated with climate change such as ocean temperature, salinity and sea surface levels.
A small genetic study, published September 30, 2019 in Nature Genetics, identified a protein linked to many genetic variants that affect heart function. Researchers are expanding the model to other organ systems and at larger scales to create a broader understanding of genes and proteins involved.
U.S. cities could see a decline in mortality rates and an improved economy through midcentury if federal and local governments maintain stringent air pollution policies and diminish concentrations of diesel freight truck exhaust, according to Cornell University research.
Hurricane Dorian is the latest example of a frightening trend. Extreme weather events are becoming more frequent, more severe and more widespread as a consequence of climate change. New research from Washington University in St. Louis provides important new insights into how different species may fare under this new normal. Faced with unprecedented change, animals and plants are scrambling to catch up — with mixed results.
Researchers have solved the three-dimensional structure of a protein complex involved in vertebrate vision at atomic resolution, a finding that has broad implications for our understanding of biological signaling processes and the design of over a third of the drugs on the market today.
To develop higher capacity batteries, researchers have looked to lithium sulfur batteries because of sulfur’s high theoretical capacity and energy density. But there are still several problems to solve before they can be put into practical applications. The biggest is the shuttling effect that occurs during cycling. To solve this problem and improve lithium sulfur battery performance, the researchers created a sandwich-structured electrode using a novel material that traps polysulfides and increases the reaction kinetics.
Scientists at Oak Ridge National Laboratory have demonstrated a way to isolate and grow targeted bacteria using genomic data, making strides toward resolving the grand challenge of uncultivated microbial “dark matter” in which the vast majority of microorganisms remain unstudied in the laboratory.
Antibiotic-resistant pathogens can be spread via washing machines. This has been proven by hygienists at the University of Bonn for a children's hospital in which a Klebsiella oxytoca type was repeatedly
A new study has revealed the most effective medications to reduce drooling in young people with a developmental disability, which can affect their socialisation, relationships and community life.
A two year study into the prevalence of antibiotic resistance in urban coastal environments shows that some beaches around Sydney have elevated levels of antibiotic resistant (AbR) bacteria following rainfall.
Flavor, safety and family attitude toward vaping are among the greatest factors influencing teenage perception of e-cigarettes, new University at Buffalo research finds.
How do weapons inspectors verify that a nuclear bomb has been dismantled? An unsettling answer is: They don't, for the most part. When countries sign arms reduction pacts, they do not typically grant inspectors complete access to their nuclear technologies, for fear of giving away military secrets.
People who achieve weight loss of 10% or more in the first five years following diagnosis with type 2 diabetes have the greatest chance of seeing their disease go into remission, according to a study led by the University of Cambridge.
University of Texas at Dallas researchers have demonstrated that imaging technology used to map the universe shows promise for more accurately and quickly identifying cancer cells in the operating room.
Cognitive-behavioral therapy (CBT) focuses on challenging and changing unhelpful thoughts and behaviors, and is a proven treatment for alcohol use disorder. However, the training and expert supervision needed to deliver consistent, high-quality face-to-face sessions is costly, limiting the widespread implementation of CBT in clinical practice. Delivering CBT through technology-based platforms, such as web-based programs and mobile apps, has potential to provide widespread and low-cost access to this evidence-based intervention ─ but it’s important to establish that tech-based CBT is as effective for alcohol treatment as the in-person format. A new report published in the journal Alcoholism: Clinical & Experimental Research systematically examines the evidence for tech-based delivery of CBT for alcohol use by combining data from multiple published studies, using a statistical technique known as meta-analysis.
Moderate drinking has been linked to a lower risk of coronary heart disease in several studies. However, the relationship between alcohol and heart disease remains controversial and is challenging to assess. Most available data are from prospective (forward-looking) studies of people in middle age or older, in whom alcohol intake was assessed at the time of study entry.
Scientists have developed a computer method that may help improve understanding and treatment of Crohn’s disease, which causes inflammation of the digestive tract. The Rutgers-led study, published in the journal Genome Medicine, used artificial intelligence to examine genetic signatures of Crohn’s in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.
In a proof-of-concept experiment, researchers from Johns Hopkins Medicine say they have successfully used microscopic man-made particles to predict the severity of patients’ chronic obstructive pulmonary disease (COPD) by measuring how quickly the particles move through mucus samples. The technique, say the researchers, could eventually help doctors deliver more effective treatments sooner.
When concerns are expressed about distrust in science, they often focus on whether the public trusts research findings. A new study, however, explores a different dimension of trust. The study examined how researchers misrepresent their research accomplishments when applying for faculty jobs.
In experiments with rats, pigs and monkeys, Johns Hopkins Medicine researchers have developed a way to deliver sight-saving gene therapy to the retina. If proved safe and effective in humans, the technique could provide a new, more permanent therapeutic option for patients with common diseases such as wet age-related macular degeneration (AMD), and it could potentially replace defective genes in patients with inherited retinal disease.
Women with asthma appear more likely to have lower levels of “free” (not attached to proteins) testosterone than women who do not have asthma, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
The three-year results from the COAPT trial demonstrated that reducing severe secondary mitral regurgitation (SMR) with the MitraClip device safely improves prognosis in selected heart failure (HF) patients. In addition, those patients that crossed over and received the MitraClip after 24 months showed the same benefits as those who received the device at the beginning of the study. Two-year data were presented at TCT 2018 and published in the New England Journal of Medicine.
Five-year results from the PARTNER 2A trial found that patients with severe aortic stenosis (AS) and intermediate surgical risk who underwent transcatheter aortic valve replacement (TAVR) had similar rates of death and disabling stroke compared to those who had surgical aortic valve replacement (SAVR). However, TAVR using a transthoracic approach had poorer outcomes compared to SAVR.
Patients with left main coronary artery disease (LMCAD) typically have a poor prognosis due to the large amount of myocardium at risk. Revascularization with either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG) has been shown to prolong survival in patients with left main disease compared with medical therapy alone. Three-year data from the large-scale randomized ECXEL trial found no significant difference in the composite rate of death, stroke or myocardial infarction (MI) between the two treatments, with a reduction in 30-day major adverse events with PCI. These results were first reported at TCT 2016 and published in NEJM.
The three-drug combination of encorafenib, binimetinib and cetuximab significantly improved overall survival (OS) in patients with BRAF-mutated metastatic colorectal cancer (mCRC), according to results of the BEACON CRC Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
The iconic extinct megatooth shark, Otodus megalodon, is an impressive gigantic shark, but new research by DePaul University’s Kenshu Shimada shows scientifically justifiable maximum size for the fossil species to be no more than about 15 meters (nearly 50 feet).
People with heart disease or defective or artificial heart valves are at increased risk of developing a potentially deadly valve infection. Rutgers researchers reported that new risk factors for this condition have emerged and that an increasing number of patients admitted to hospitals for other diseases are at risk of contracting this potentially lethal cardiac infection.
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