Researchers investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients. They found the procedure to be safe and the results to be encouraging.
By using sound waves, scientists have begun to explore fundamental stress behaviors in a crystalline material that could form the basis for quantum information technologies.
في تجربة سريرية صغيرة للسلامة والجدوى، أظهر باحثو Mayo Clinic لأول مرة أن الخلايا الهرمة يمكن إزالتها من الجسم باستخدام أدوية تُسمى "الأدوية المضادة للشيخوخة". لم يتم التحقق من النتيجة في تحليل الدم فحسب، بل أيضًا في تغيرات وفرة الخلايا الهرمة في الجلد والأنسجة الدهنية. تظهر النتائج في مجلة EBioMedicine.
在一项小型安全性和可行性临床试验中，Mayo Clinic的研究人员首次证明，使用被称为“senolytic”的抗衰老药物可以清除人体内的衰老细胞。该结果不仅在血液分析中得到验证，而且在皮肤和脂肪组织衰老细胞丰度的变化中得到证实。研究结果发表在 EBioMedicine期刊上。
Em um ensaio clínico de segurança e viabilidade de pequena escala, pesquisadores da Mayo Clinic demonstraram pela primeira vez que células senescentes podem ser removidas do corpo por meio de medicamentos denominados "senolíticos". O resultado foi confirmado por análises sanguíneas e por alterações na abundância de células senescentes nos tecidos epitelial e adiposo. Os resultados foram publicados na revista EBioMedicine.
Dans le cadre d'un essai clinique d'innocuité et de faisabilité de faible portée, les chercheurs de la Mayo Clinic ont démontré pour la première fois que des médicaments qualifiés de « sénolytiques » pouvaient éliminer les cellules sénescentes de l'organisme. Le résultat a été vérifié non seulement dans les analyses sanguines, mais également dans les variations de quantités des cellules sénescentes de la peau et des tissus adipeux. Les résultats sont publiés dans la revue scientifique EBioMedicine.
In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals.
In einer kleinen klinischen Sicherheits- und Machbarkeitsstudie haben Forscher der Mayo Clinic zum ersten Mal nachgewiesen, dass alternde Zellen mit Medikamenten, die als „Senolytika“ bezeichnet werden, aus dem menschlichen Körper entfernt werden können. Das Ergebnis wurde nicht nur in der Blutanalyse, sondern auch in der veränderten Menge seneszenter Zellen in Haut- und Fettgewebe bestätigt. Die Ergebnisse erscheinen in der Zeitschrift EBioMedicine.
New research from Michigan State University and Johns Hopkins University is the first to uncover the specific data leaked through hospital breaches, sounding alarm bells for nearly 170 million people.
Disrupting a metabolic pathway in the liver in a way that creates a more “cancer-like” metabolism actually reduces tumor formation in a mouse model of liver cancer. This surprising finding from a Univ. of Iowa study identifies the mitochondrial pyruvate carrier as a potential target for preventing liver cancer.
The researchers used a sophisticated electron microscope that can take pictures of structures at the atomic level to examine the virus as it interacted with the transferrin receptor, or TfR, a protein on the surface of the cell that helps manage a body’s iron uptake.
Women who ate the popular Puerto Rican condiment sofrito, which contains onions and garlic, more than once per day had a 67% decreased risk of breast cancer. It's the first population-based study examining the association between onion and garlic consumption and breast cancer in Puerto Rico.
To find out whether an intervention could increase the number of discussions between clinicians and patients with heart failure about the kinds of treatments they would want at the end of their lives, also known as advance care planning, researchers at The Mount Sinai Hospital developed a rigorous six-center study to investigate a novel communication intervention. The study appears in the Journal of the American College of Cardiology.
After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.
A new imaging study of the mummified arteries of people who lived thousands of years ago revealed that their arteries were more clogged than originally thought, according to a proof-of-concept study led by a researcher with The University of Texas Health Science Center at Houston (UTHealth). It is in the October print edition of the American Heart Journal.
Scientists at the University of Surrey have discovered that a natural antioxidant commonly found in green tea can help eliminate antibiotic resistant bacteria.
As the first research of its kind, the findings may help growers increase the marketability of their ornamental horticulture products through labeling. Consumer preferences, visual attention and willingness-to-pay were measured and tested to determine how each label or text combination impacted a consumer’s willingness to pay for a particular fruit plant.
Nurse burnout impacts both nurses and patients, and significantly influences the retention of nurses in the healthcare setting, research shows. But could burnout be a symptom of something larger?
If children are exposed to bias against one person, will they develop a bias against that person’s entire group? The answer is yes, according to new research from University of Georgia social psychologist Allison Skinner.
A new study of men and women with hypersexual disorder has revealed a possible role of the hormone oxytocin, according to results published in the journal Epigenetics. The finding could potentially open the door to treating the disorder by engineering a way to suppress its activity.
A recent Rutgers study identified factors that may put people who responded to the 9/11 terrorist attacks at the World Trade Center (WTC) at increased risk for cancers of the head and neck, such as oral cavity, oropharyngeal, and laryngeal cancers.
A key theory that attributes the climate evolution of the Earth to the breakdown of Himalayan rocks may not explain the cooling over the past 15 million years, according to a Rutgers-led study. The study in the journal Nature Geoscience could shed more light on the causes of long-term climate change.
A University of California, Irvine-led team of scientists has discovered how newly identified neural circuits in the brain’s hippocampal formation play a critical role in object-location learning and memory.
Researchers at UC San Diego say they are getting closer to identifying the mechanisms of autism spectrum disorder, revealing a critical gene network that is disrupted and which helps predict severity of symptoms.
When we eat red meat, the animal carbohydrate Neu5Gc is incorporated in our tissues, where it generates inflammation. UC San Diego researchers discovered how gut bacteria enzymes strip our cells of Neu5Gc, introducing the possibility of using the enzymes to reduce the risk of inflammatory diseases.
A new approach to producing indolent scaffolds could streamline development and production of small-molecule pharmaceuticals, which comprise the majority of medicines in use today.
Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.
New Research Reveals a Disconnect Between Awareness of the Risk and Magnitude of the Problem
The quantum superposition principle has been tested on a scale as never before in a new study by scientists at the University of Vienna in collaboration with the University of Basel. Hot, complex molecules composed of nearly two thousand atoms were brought into a quantum superposition and made to interfere. By confirming this phenomenon – “the heart of quantum mechanics”, in Richard Feynman’s words – on a new mass scale, improved constraints on alternative theories to quantum mechanics have been placed. The work will be published in Nature Physics.
An international team of scientists has figured out how to capture heat and turn it into electricity. The discovery, published last week in the journal Science Advances, could create more efficient energy generation from heat in things like car exhaust, interplanetary space probes and industrial processes.
Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health.
UC San Diego research supplies a blueprint for a future generation of electrode sensors—notably microscopically slender diamond needles—that utilizes existing yet nontraditional materials and fabrication procedures for recording electrical signals from every neuron in the cortex at the same time.
Value in Health, the official journal of ISPOR, announced the publication of an analysis showing that while value assessment frameworks are moving closer to meeting the challenge of accurately measuring value and informing healthcare decisions, more progress is needed before widespread adoption and use.
Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of research demonstrating that discrete choice experiments are able to predict real-world healthcare choices.
In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the U.S. with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.
Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.
The fight against neuromuscular diseases will come to the forefront this October with the 2019 American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) Annual Meeting in Austin, Texas.
The National Institute of Allergy and Infectious Diseases research contract is one of the largest ever awarded to UMSOM and includes an initial award of approximately $2.5 million to conduct clinical testing of influenza vaccines. Total funding over seven years could be as much as $201 million if all options are exercised in the NIAID contract.
A novel vaccine at Penn Medicine protected almost all animal subjects exposed to the herpes virus
Climate change and over-tapped waterways could leave developing parts of Asia without enough water to cool power plants in the near future, new research indicates. The study found that existing and planned power plants that burn coal for energy could be vulnerable. The work was published today in the journal Energy and Environment Science.
Researchers at Michigan State University say that true, human-level intelligence remains a long way off, but their new paper published in The American Naturalist explores how computers could begin to evolve learning in the same way as natural organisms did – with implications for many fields, including artificial intelligence.
A new study published today in Nature Communications shows a promising alternative for those who have to take a daily pill regimen.
Feature describes improved model for forecasting the crucial balance of pressure at the edge of a fusion plasma.
The New York Times makes a concerted effort to drive home the point that climate change is real, but it does a poor job of presenting the basic facts about climate change that could convince skeptics, according to a review of the paper's coverage since 1980.
Individuals who make concrete plans to meet their goals may engage in more physical activity, including visits to the gym, compared to those who don't plan quite so far ahead, research shows.
Analyzing reflections of seismic pressure waves by the subseafloor geology off southwestern Japan, researchers at Kyushu University have found the first evidence of a massive gas reservoir where the Earth's crust is being separated. Depending on its nature
If you could travel back in time 100,000 years, you'd find yourself living among multiple groups of humans, including anatomically modern humans
An internationally respected group of scientists, including Professor Francois Engelbrecht from the University of the Witwatersrand
Profiles of Native American DNA in modern populations show patterns of migration across the U.S.
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