By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy.
Using whole exome sequencing, CHOP researchers discovered the genetic mutation responsible for a condition that prevents patients from making B cells and antibodies to fight infections. The study describing the condition, which CHOP researchers named PU.1 Mutated agammaglobulinemia (PU.MA), was published today in the Journal of Experimental Medicine.
Thirty days of radiation treatments — five days a week, with Saturdays and Sundays off — are difficult for even the toughest of adults. But for a child, they’re even harder to bear. They involve fasting, waking up early, and lying in a dark room alone, without even your parents there for support. But if during treatment you can take a trip to Agrabah to hang out with Aladdin, Jasmine, and the rest of the characters in Disney’s live-action version of “Aladdin,” it makes the sessions a lot easier to bear — not to mention it makes time go by a lot faster. Thanks to a new innovation at the CU Cancer Center, patients like 5-year-old Piper Lardes are able to do just that — watch their favorite show or movie during their treatment to make the whole experience just a little easier. The technology, called Radflix, has a calming effect on parents as well.
WFIRM scientists are tackling necrotizing enterocolitis with a human placental-derived stem cell (hPSC) therapy strategy that is showing promising results.
In addition to the physical health problems caused by the pandemic, there has been a heavy mental health toll from months of lockdown and upheaval - particularly for children and teens.
Green tea supplements modulate facial development of children with Down syndrome A new study led by Belgian and Spanish researchers published in Scientific Reports adds evidence about the potential benefits of green tea extracts in Down syndrome.
Feeding method and affectionate touch patterns in depressed and non-depressed mothers and babies as well as infant’s EEG activity showed that mother-infant affectionate touch differed as a function of mood and feeding method (breastfeeding and bottle-feeding). Infants in the depressed and bottle-fed group reduced touch toward their mothers while breastfeeding had a positive effect on both mother and baby. Infants of depressed and breastfeeding mothers showed neither behavioral nor brain development dysregulation previously found in infants of depressed mothers.
Black children have significantly higher rates of shellfish and fish allergies than White children, in addition to having higher odds of wheat allergy, suggesting that race may play an important role in how children are affected by food allergies, researchers at Ann & Robert H. Lurie Children’s Hospital of Chicago, Rush University Medical Center and two other hospitals have found.
A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers.
UC Davis MIND Institute researchers used machine learning to crunch 10,000 autoantibody pattern combinations to identify maternal biomarkers associated with a sub-type of autism. The findings have implications for early diagnosis and intervention.
If the Nation’s Report Card, an annual report formerly known as the National Assessment of Educational Progress (NAEP), was reimagined to include physical and emotional health in addition to academics, the United States would receive a C average, says University at Buffalo educational policy expert Jaekyung Lee.
A first-of-its-kind, international study of 107,000 children finds that higher temperatures are an equal or even greater contributor to child malnutrition than the traditional culprits of poverty, inadequate sanitation, and poor education. The 19-nation study is the largest investigation to date of the relationship between our changing climate and children's diet diversity. Of the six regions examined--in Asia, Africa, and Central and South America--five had significant reductions in diet diversity associated with higher temperatures.
As a former school nurse in the Columbia Public Schools, Gretchen Carlisle would often interact with students with disabilities who took various medications or had seizures throughout the day.
Substances present in cooked meats are associated with increased wheezing in children
A world-first study by the University of South Australia has found that survivors of child abuse are more than twice as likely to die young than children who have never come to the attention of child protection services.
In a retrospective case study, Mayo Clinic researchers have found that antibiotics administered to children younger than 2 are associated with several ongoing illnesses or conditions, ranging from allergies to obesity. The findings appear in Mayo Clinic Proceedings.
Premature infants born earlier than 28 weeks gestation who experience fewer needle pokes while receiving life-saving care in the neonatal intensive care unit may have better growth of a part of the brain called the thalamus. The new study is published in the October 21, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
“She’s a bundle of joy, she’s a blessing. She’s just life.” That’s what Cariorl Mayfield of Niagara Falls, NY, says about his young daughter, Chasity, a year after she went through a complex series of therapies at the Roswell Park Oishei Children’s Cancer and Blood Disorders Program to treat the leukemia she was diagnosed with at only 5 weeks old.
Babies aren’t born knowing how to poop. It takes them a little while after they’re born to get the hang of it.
Epigenetic disorders are more common among children born through assisted reproductive technology. A new mouse study suggests that the fertility treatments themselves are to blame, not the age of the mother.
New research shows that the body’s own microbes are effective in maintaining immune cells and killing certain oral infections.
Research from the St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project has revealed new vulnerabilities and leads for treatment of rhabdomyosarcoma
Cardiac late effects will be the focus of an upcoming ‘Survivors Family Education Night’ hosted by Rutgers Cancer Institute of New Jersey. Supported by a grant from the National Children’s Cancer Society, the event targets pediatric cancer survivors.
Scientists exploring how to tame random gene fluctuations as the embryos that become our bodies start to form have identified a control switch in the vertebrate segmentation clock of developing zebrafish. The researchers report in Cell Reports their findings could uncover methods for modulating genetic signals to prevent birth defects or cancers rooted at the earliest stages of development.
Without a doctor or dentist’s guidance, some parents don’t follow national recommendations for early dental care for their children, a new national poll finds.
Eight years ago, Dr. Jeff Avansino, a surgeon at Seattle Children’s, and his wife, Dr. Amy Criniti, welcomed their third child – a boy named Luke.
In an assessment of their “depression literacy” program, which has already been taught to tens of thousands, Johns Hopkins researchers say the Adolescent Depression Awareness Program (ADAP) achieved its intended effect of encouraging many teenagers to speak up and seek adult help for themselves or a peer.
New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells). Published Dec. 27 and conducted largely in genetic models of obese mice, the study shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment – the blood-making factory in our bodies.
Pretty much all toys can look inviting to children. But it’s important for adults who are buying toys this holiday season look beyond the flashing lights and cool noises to make sure they are safe.
Playing a video game that rewards participants for holding various “ninja” poses could help children and youth with autism spectrum disorder (ASD) improve their balance, according to a recent study in the Journal of Autism and Developmental Disorders led by researchers at the University of Wisconsin-Madison.
The popularity of the Nerf “blaster” toy gun has created an active market for inexpensive off-brand versions of the Nerf darts, but new data from Virginia Tech suggests that the off-brand darts are two to three times more likely to cause eye injuries.
A national survey of more than 200 pediatric primary care physicians found that while over three-quarters addressed at least one parental health issue, such as maternal depression or parental tobacco use, during child health visits and a majority recognized the impact of such issues on children’s health, fewer felt responsible for addressing them.
Any amount of alcohol exposure during pregnancy can cause extreme lasting effects on a child, according to new research from Binghamton University, State University of New York.
High blood pressure is often thought of as a grown-up problem, but nearly 1 in 30 children suffer from the condition. Unfortunately, many of those pediatric cases go undetected.
An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.
Some kids like to be scared on Halloween, while others prefer to grab the candy and run. No kid enjoys allergy and asthma symptoms. Kids who suffer from food allergies can find Halloween particularly frightful if they are worried a treat might send them to the emergency room.
In a landmark decision for the field of cancer immunotherapy, the U.S. Food and Drug Administration (FDA) today approved a personalized cellular therapy developed by the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP) for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.
Study uses fMRI brain scans to document relationship between neural activity and risk for obesity
Parents can make sure their children get the new school year off to a healthy start by getting checkups for them during the summer break.
Join our virtual press briefing on August 10 at 11 am ET to hear from these organizations about new research, stories of successful programs in communities, and experts who can speak to the need to ensure all children have access to nutritious food and safe places to be physically active.
A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16. In a recent study, researchers showed that allowing surgeons to prep on a 3D-printed model of the patient’s hip joint cut by about 25 percent the amount of time needed for surgery when compared to a control group.
Some falls are just part of childhood. Learning to walk and nursing scraped knees are milestones that few kids escape. But more serious tumbles – from beds, stairs, playground equipment and windows – are often the most easily prevented.
A new study in Annals of Allergy, Asthma and Immunology showed that even kids who were prescribed an epinephrine auto injector didn’t receive the life-saving medication when they needed it.
The Golden Week program developed by UAB’s Regional Neonatal Intensive Care Unit was recently recognized nationally for its standardized set of practices for premature infants, providing them with quality care in their first week of life.
Nurses in neonatal intensive care units (NICU) spend close to 13,000 hours every year managing breast milk for the nearly 500,000 babies across the United States that require special and often critical care in the first months of their lives. That’s 13,000 hours (the annual equivalent of six full-time nurses) spent on just what these nurses call “bartending” – not feeding, just monitoring, labeling, printing, and logging infant-specific nutritional management. Enter Keriton, a new breast milk management system designed for nurses and new moms, by nurses and new moms, that the Hospital of the University of Pennsylvania’s Intensive Care Nursery (ICN) began testing last month. Unlike other apps that are available to only moms or to only nurses, Keriton is the first integrated system that operates on a HIPAA-compliant and secure server, allowing for “process automation” – meaning, moms use the app to log and track how much and when they are pumping, and the information is automatically syn
St. Jude Children’s Research Hospital scientists have used a drug being developed to fight solid tumors to restore normal metabolism in flu-infected cells and reduce viral production without the threat of drug resistance
“Internet addiction in children and adolescents is a growing problem and part of our culture. The internet is a wonderful servant, but a cruel and crippling master,” Dr. Rosenberg said. “There is some debate in the field about whether internet addiction is real addiction or pathology. We contend it exists, and it can devastate children and their families. But there are differences – as well as similarities – with other addictive behavior, and you can't just stop with a diagnosis of internet addiction, since there are always underlying conditions that must be aggressively diagnosed and treated for the long-term benefit of the internet addiction.”
Tips for your daughter's first OB/GYN visit from Dr. Julie Jacobstein, a board-certified adolescent gynecologist with LifeBridge Health.
A new study from The Ohio State University Wexner Medical Center finds athletes with attention deficit/hyperactivity disorder (ADHD) are more likely to compete in team contact sports than individual sports, which could increase their risk of injury.
Researchers at the University of California San Diego School of Medicine, with colleagues in Ecuador and Minnesota, have found altered short-term neurological behaviors in children associated with a peak pesticide spraying season linked to the Mother’s Day flower harvest. This study examined children who did not work in agriculture but who lived in agricultural communities in Ecuador.
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