Curated News: National Center for Advancing Translational Sciences (NCATS)

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Released: 3-Mar-2023 3:40 PM EST
“COVID rebound” is common, even in untreated patients
Scripps Research Institute

“COVID rebound,” in which evidence of the illness disappears and then returns days or weeks later, is surprisingly common—whether or not patients are given the antiviral Paxlovid.

Newswise: Adding antipsychotic med to antidepressant may help older adults with treatment-resistant depression
2-Mar-2023 5:35 PM EST
Adding antipsychotic med to antidepressant may help older adults with treatment-resistant depression
Washington University in St. Louis

Psychiatry researchers at Washington University School of Medicine in St. Louis, led a multicenter study that found, in older adults with treatment-resistant depression, that augmenting an antidepressant drug with aripiprazole helped a significant number of patients.

Released: 2-Mar-2023 7:00 AM EST
باحثون من مايو كلينك يربطون بين سرطان المبيض وتكاثر عدد البكتيريا في الحَيُّوم الدقيق 
Mayo Clinic

عادة ما يوجد تكاثر لنوع معين من الميكروبات في الجهاز التناسلي للنساء المصابات يسرطان المبيض، وفقًا لدراسة جديدة من مركز مايو كلينك لنهج الطب الشخصي. إن هذا الاكتشاف المنشور في مجلة التقارير العلمية يقوي الأدلة التي تشير إلى أن المكون البكتيري للحَيُّوم الدقيق - وهو مجتمع من الكائنات الحية الدقيقة يتكون أيضًا من فيروسات وخمائر وفطريات - من المؤشرات الهامة للكشف المبكر عن سرطان المبيض وتشخيصه والتنبؤ بسير المرض.

Newswise: Two new papers demonstrate use of Outbreak.info as one-stop online source for COVID data
Released: 23-Feb-2023 5:45 PM EST
Two new papers demonstrate use of Outbreak.info as one-stop online source for COVID data
Scripps Research Institute

While COVID-19 may be transitioning from a “pandemic” to an “endemic” phase, it remains critically important to continue tracking the virus in real-time.

Newswise: Protein Biomarkers Identified in Women Who Developed Perinatal Depression and Anxiety
Released: 23-Feb-2023 12:40 PM EST
Protein Biomarkers Identified in Women Who Developed Perinatal Depression and Anxiety
Cedars-Sinai

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester. The study is published in the American Journal of Obstetrics & Gynecology.

Newswise: Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity
Released: 16-Feb-2023 12:35 PM EST
Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity
University of California San Diego

UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.

Released: 14-Feb-2023 7:00 AM EST
مراجعة على مدار 20 عامًا تشير إلى إمكانية عودة الرياضيين بأمراض قلب وراثية لممارسة الرياضات التنافسية 
Mayo Clinic

عادة ما يُستبعد الرياضيون المصابون بأمراض القلب الوراثية من المشاركة في الرياضات التنافسية بسبب الخطر المُتوقع للإصابة بتوقف القلب المفاجئ. في حين أن تخوف الأطباء قد يكون مبررًا، لكن هل هذه بالضرورة أفضل طريقة للتعامل مع الأمر؟

Released: 14-Feb-2023 7:00 AM EST
Una investigación de 20 años sugiere que los deportistas con enfermedades cardíacas genéticas pueden volver a competir sin correr peligro
Mayo Clinic

Los investigadores de Mayo Clinic hicieron una revisión de los atletas que se trataron en Mayo durante un período de 20 años, y los hallazgos publicados en Mayo Clinic Proceedings sugieren que después de que la afección del paciente se haya evaluado y tratado de manera adecuada, es factible que los atletas puedan volver a sus actividades de forma segura.

Released: 14-Feb-2023 7:00 AM EST
Avaliação de 20 anos sugere que atletas com doença cardíaca genética podem retornar com segurança aos esportes competitivos
Mayo Clinic

Atletas com doença cardíaca genética frequentemente são considerados inaptos a participar de esportes competitivos devido ao risco de parada cardíaca súbita. Embora a intenção dos médicos seja compreensível, será que essa é necessariamente a melhor abordagem?

Newswise: New diagnostic test is 1,000 times more sensitive than conventional tests
Released: 9-Feb-2023 3:40 PM EST
New diagnostic test is 1,000 times more sensitive than conventional tests
Washington University in St. Louis

Thinking beyond COVID-19, a team led by Srikanth Singamaneni at the McKelvey School of Engineering developed a new point-of-care diagnostic test that is 1,000 times more sensitive than conventional rapid tests and can quantify concentrations of proteins.

   
31-Jan-2023 6:00 AM EST
Financial coaching for parents in clinic leads to higher attendance at well-child health care visits for their young children
University of California, Los Angeles (UCLA), Health Sciences

Implementing financial coaching for parents of infants in a pediatric primary care setting reduced missed well-child care visit rates by half and significantly improved receipt of vaccinations at a timely age, according to a new community-partnered pilot study led by UCLA researchers.

Newswise: Markey Cancer Center study addresses colorectal cancer disparities in Black communities
Released: 10-Jan-2023 3:45 PM EST
Markey Cancer Center study addresses colorectal cancer disparities in Black communities
University of Kentucky

A new University of Kentucky Markey Cancer Center study highlights the need for increased outreach and education to reduce colorectal cancer screening disparities in Black communities. According to the qualitative study published in the Journal of Cancer Education, people in Kentucky’s Black communities may not be aware about all of the colorectal cancer screening options available to them, particularly stool-based tests.

Newswise: Which Children Are at Risk After a Mild Traumatic Brain Injury?
Released: 30-Nov-2022 9:05 AM EST
Which Children Are at Risk After a Mild Traumatic Brain Injury?
Children's Hospital Los Angeles

When children have a mild traumatic brain injury with intracranial hemorrhage, how long do they need to stay in the hospital? Which patients should go to the intensive care unit? What neuroimaging should physicians do—and how often do they need to repeat scans?Currently, hospitals and physicians across the country answer these questions quite differently.

Newswise: Study Shows Paxlovid Can Safely Be Used to Reduce Risk of Severe COVID in People Who Are Pregnant
Released: 29-Nov-2022 5:25 PM EST
Study Shows Paxlovid Can Safely Be Used to Reduce Risk of Severe COVID in People Who Are Pregnant
Johns Hopkins Medicine

Findings from a Johns Hopkins Medicine research study published today in JAMA Network Open provide strong evidence that people who are pregnant and have been infected with SARS-CoV-2 (the virus that causes COVID-19) can safely take the antiviral drug Paxlovid to reduce the possibility of severe disease.

Released: 17-Oct-2022 11:00 AM EDT
Icahn School of Medicine at Mount Sinai Receives National Institutes of Health Award to Accelerate Development of New Treatments
Mount Sinai Health System

The Icahn School of Medicine at Mount Sinai has been awarded a five-year, $55.5 million grant from the National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) Program that will benefit the diverse patient population Mount Sinai serves by accelerating the development of new treatments for leading health conditions, including cardiorespiratory and psychiatric disorders, diabetes, malignancies, and infectious diseases.

Newswise: Cedars-Sinai Study Highlights Cancer Disparities in LA County
Released: 5-Sep-2022 12:05 PM EDT
Cedars-Sinai Study Highlights Cancer Disparities in LA County
Cedars-Sinai

People in Los Angeles County experience differences in cancer risk and survival depending on a variety of factors such as race/ethnicity, gender, sexual orientation, geographic location and socioeconomic status, according to a new study by investigators at Cedars-Sinai Cancer.

Released: 25-Aug-2022 11:45 AM EDT
National Institutes of Health renews Mayo Clinic's $48 million Clinical and Translational Science Award
Mayo Clinic

Mayo Clinic announced today that its Center for Clinical and Translational Science has successfully renewed funding for its research grant from the National Institutes of Health National Center for Advancing Translational Sciences for five more years.

Released: 22-Jul-2022 8:05 AM EDT
‘Smart Necklace’ Biosensor May Track Health Status Through Sweat
Ohio State University

Researchers have successfully tested a device that may one day use the chemical biomarkers in sweat to detect changes in a person’s health.

   
Released: 18-Aug-2021 1:40 PM EDT
Heat-Controllable CAR T Cells Destroy Tumors and Prevent Relapse in New Study
Georgia Institute of Technology

In a study published in the journal Nature Biomedical Engineering, Georgia Tech researchers build on the lab’s body of work exploring remotely controlled cell therapies, in which the researchers can precisely target tumors, wherever they are in the body, with a local deposition of heat. The latest study shows the system cured cancer in mice, and the team’s approach not only shrunk tumors but prevented relapse – critical for long-term survival. Further studies will delve into additional tailoring of T-cells, as well as how heat will be deposited at the tumor site.

   
17-Aug-2021 8:30 AM EDT
Study: Pregnant women do well with COVID vaccine
University of Washington

A survey of more than 17,000 pregnant and lactating individuals who received the COVID-19 vaccine showed that the individuals did not experience symptoms any more severe than their non-pregnant counterparts.



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