Feature Channels: OBGYN

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Despite its substantial impact on pregnancy outcomes, scientists know little about how group B streptococcus (GBS) establishes an in utero infection. In a paper published in the Journal of Clinical Investigation, Dr. Lakshmi Rajagopal, a principal investigator in Seattle Children’s Research Institute Center for Global Infectious Disease Research describes a newly uncovered mechanism by which GBS gains access to a woman’s uterus.

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The longer a patient with a positive screening result waits for diagnostic testing, the worse their cancer outcomes may become, according to a literature review of breast, cervical, colorectal, and lung studies in the journal led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

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Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

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Newly expanded, the Program for Abdominal and Pelvic Health at Rush brings together a team of experts to address the complexity of pelvic health conditions and treat men and women suffering from them.

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Researchers nationwide have reached a major milestone in describing the genetic landscape of cancer. Scientists at Washington University School of Medicine in St. Louis and other institutions have completed the genetic sequencing and analyses of more than 11,000 tumors from patients, spanning 33 types of cancer — all part of The Cancer Genome Atlas (TCGA) project, funded by the National Cancer Institute and National Human Genome Research Institute.

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Researchers from The University of Texas MD Anderson Cancer Center have found a startling amount of new information about molecular features of tumors as well as identified previously unknown cancer subtypes based on a comprehensive analysis of 2,579 tumors from breast and four different types of gynecologic cancers. These new findings potentially could serve as a launching pad for future therapeutic studies.

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UNC School of Medicine researchers have identified mutations to the bacterium Neisseria gonnorrhoeae that enable resistance to ceftriaxone that could lead to the global spread of ceftriaxone-resistant “superbug” strains.

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A new study from a University of Iowa-led research team finds that women who are considering pregnancy would benefit from greater fitness. Using 25 years of data on pre-pregnant women, the researchers report that higher levels of pre-pregnancy fitness are associated with a reduced risk of developing gestational diabetes.

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UCLA scientists discovered higher levels of a protein called humanin in the placenta tissue of women who give birth to severely underweight infants. The researchers suspect that humanin rises to protect the fetus during placenta failure.

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Gary Shapiro, President and CEO of the Consumer Technology Association (CTA)™, which annually produces CES®, the largest technology and innovation show in the world, will deliver a keynote address at the 6th International Symposium on Focused Ultrasound on Tuesday, October 23, 2018, in Reston, Virginia.

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Women who undergo hormone therapy to relieve menopausal symptoms tend to have less fat tissue, particularly in the abdomen, than other menopausal women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

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Click here to go directly to Newswise's Obesity News Source

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AACC is pleased to see an additional $2 million for lab test harmonization in the FY 2018 omnibus spending package. The association has worked to advance harmonization – or uniform test results -- for more than a decade, most recently leading efforts to raise awareness in Congress of the need for CDC funding for harmonization. AACC is gratified that its multiyear effort has resulted in a positive outcome. The new funding will enable CDC to broaden its harmonization initiative, which is vital to ensuring that patients receive accurate diagnoses and effective medical treatment.

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A few months into her pregnancy, Anisah Brown had a routine ultrasound that detected a large hole in her baby’s diaphragm. Her baby had been diagnosed with a congenital diaphragmatic hernia, or CDH. The hole would let the liver, stomach and other internal organs compress the lungs, leaving them little room to develop. Her doctor told her there was no hope. But that was before she came to the Cincinnati Fetal Center.

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Known as the silent killer, ovarian cancer is notorious for avoiding detection until it has progressed to an advanced stage. New research from Virginia Tech on fluid shear stress in the abdominal cavity is moving physicians closer to earlier diagnosis and more effective treatment.

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Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers developed by researchers at the Johns Hopkins Kimmel Cancer Center.

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A new study has identified two genes associated with hyperemesis gravidarum, whose cause has not been determined in previous studies. The genes, known as GDF15 and IGFBP7, are both involved in the development of the placenta and play important roles in early pregnancy and appetite regulation.

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Loyola Medicine Recognizes Endometriosis Awareness Month

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The oral diabetes medication metformin seems to reduce the chance of a late miscarriage and premature birth among women with polycystic ovary syndrome (PCOS) but does not affect their rate of developing gestational diabetes, a multicenter study finds. The results were presented Tuesday at ENDO 2018, the Endocrine Society’s 100th annual meeting in Chicago, Ill.

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Oral micronized progesterone (OMP) may diminish hot flashes and night sweats in perimenopausal women, new research from Canada reports. The results will be presented on Monday, March 19 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

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A new study shows that pregnant women and new moms aware of the 2017 guidelines on early introduction of peanuts to prevent allergy are still hesitant to put them in place. And not everyone has heard about them.

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Race and pre-pregnancy body mass index (BMI) both affect leptin and adiponectin levels, and leptin levels in mid-pregnancy may be an important predictor of weight gain during pregnancy, new research suggests. The results will be presented on in a poster on Sunday, March 18 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

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Young women with premature ovarian insufficiency (POI) may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests. The preliminary results from the ongoing ROSE clinical trial will be presented Tuesday at ENDO 2018, the 100th annual meeting of the Endocrine Society, in Chicago, Ill.

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Giving one year of estrogen replacement to female athletes with exercise-induced menstrual irregularities improves drive for thinness, body dissatisfaction and uncontrolled eating, a new study finds. The research results will be presented Saturday, March 17, at ENDO 2018, the annual scientific meeting of the Endocrine Society, in Chicago, Ill.

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Imagine if doctors could diagnose their patients with lung or esophageal cancer by simply swabbing the inside of their cheeks. Vadim Backman, a biomedical engineer at Northwestern University, has developed a new technology that could make that seemingly simple solution a reality.

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For the first time, researchers have developed a way to sequence the entire genome of a fetus by modifying the prenatal testing method known as amniocentesis. This groundbreaking finding, published in AACC’s journal Clinical Chemistry, could improve care for genetic diseases in childhood by dramatically increasing the number of these conditions that can be detected during pregnancy.

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Two landmark developments in medicine pave the way for quality medical care to address America’s largest and most costly preventable health problem – unhealthy substance use and addiction involving all addictive substances. These changes are designed to increase the number of addiction medicine physician specialists who can provide direct patient care and consultation, teach other providers and thereby drive knowledge across health care, and help policymakers and the public understand and effectively respond to our current health crisis.

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The Consortium of Universities for Global Health (CUGH), the Perlmutter Cancer Center, and the Department of Population Health at NYU Langone Health are issuing the “New York Challenge,” an ambitious campaign to end cervical cancer worldwide.

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In a new Johns Hopkins study, researchers have added to evidence that Trichomonas vaginalis (TV), the world’s most common curable sexually transmitted infection (STI), disproportionately affects the black community.

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While cervical cancer – one of the most common cancers in women – has significantly decreased in the United States, it is still the second most common cancer in women who live in less developed countries, according to the World Health Organization. Women in sub-Saharan Africa (SSA) have the largest age-standardized incidence and mortality rates of this potentially preventable and non-communicable disease due to the difficulty in implementing prevention, screening, and treatment programs

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Many women suffer from acid reflux in early pregnancy, but it can often be confused with other early pregnancy symptoms or go undiagnosed.

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According to a new study by The Wistar Institute, EZH2 inhibitors that are currently in clinical development for hematological malignancies and solid tumors may be effectively targeted to epithelial ovarian cancers overexpressing the CARM1 protein.

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ASU students design user-friendly pap smear kit, win top prize

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Industrial design students use ingenuity to create more effective vision of future of women’s health care; product heads to national show

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Researchers at Washington University School of Medicine in St. Louis have designed sugar molecules that block E. coli bacteria from binding to urinary tract tissues, allowing the bacteria to be washed out of the urinary tract. The compounds represent a step toward treating UTIs without antibiotics.

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All women who have unwanted dark, course hair growing on the face, chest or back should undergo testing for polycystic ovary syndrome (PCOS) and other underlying health problems, Endocrine Society experts concluded in an updated Clinical Practice Guideline released today.

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Johns Hopkins experts present at CROI 2018.

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By measuring the sagging of the vaginal walls in more than a thousand volunteers for up to nine years annually, a team of Baltimore physicians reports the creation of a long-awaited baseline measure of the rate of progression of so-called pelvic organ prolapse. The baseline, they say, should provide a foundation for reliable studies and a more rational search for factors that prevent or ease the condition.

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Backed by a $3.6 million National Institutes of Health grant, a Michigan State University researcher is looking to reduce postpartum depression by expanding a preventative program that has already shown it can cut the postpartum depression rate in half among low-income women.

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A study in the Journal of Neuroscience reveals that activation of a pregnant mother’s immune system can affect her baby’s brain development. Researchers at CHLA, found that short- and long-term brain functioning can be influenced by immune system activity during the third trimester of gestation.

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When women take the common diabetes medication metformin during pregnancy, it may put their children at increased risk of having obesity or overweight.

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Mom's inflammatory response shapes "wiring" of her child's brain. Similar networking changes linked to autism and ADHD.

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Women face several options when it comes to birth control, so potential side effects often factor into their decision. Depression is a common concern for many women, but a new study by researchers at The Ohio State University Wexner Medical Center is putting patients at ease.

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The new president of the Society for Maternal-Fetal Medicine (SMFM) is Sean Blackwell, M.D., professor and chair of the Department of Obstetrics, Gynecology, and Reproductive Sciences at McGovern Medical School at the University of Texas Health Science Center in Houston (UTHealth).

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At most US maternity units, women in labor are put on nil per os (NPO) status—they're not allowed to eat or drink anything, except ice chips. But new nursing research questions that policy, showing no increase in risks for women who are allowed to eat and drink during labor. The study appears in the March issue of the American Journal of Nursing, published by Wolters Kluwer.

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University of Utah Health developed the HER Salt Lake Contraceptive Initiative to evaluate women's contraception choices if cost is not a factor. The research findings are published in the February 22 issue of the American Journal of Public Health.

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A very common cause of infertility in women is a condition called polycystic ovary syndrome (PCOS). Women are usually diagnosed with PCOS in their 20s or 30s after difficulties with getting pregnant, but the condition affects 1 in 10 women of childbearing age (15 to 44) and is linked to health problems other than infertility.

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Researchers at the University of Illinois at Chicago will conduct a study to determine how the use of menstrual cups helps prevent vaginal infections and sexually transmitted infections.“One of the most common vaginal infections, bacterial vaginosis, doubles the risk for acquiring or transmitting HIV,” said Supriya Mehta, associate professor of epidemiology in the UIC School of Public Health and principal investigator on the study.

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Nicole Elliot and Jessica Graham were all smiles as they cuddled and introduced their respective newborn daughters on a sunny fall afternoon in an examination room on the third floor of Sinai Hospital of Baltimore’s Rosenbloom Building at Sinai Community Care, where the proud moms had started a friendship a few months earlier.