Alzheimer's Awareness Month: How Can Sex and Gender Impact Canadians’ Risk of Developing Alzheimer’s Disease?
Canadian Institutes of Health Research (CIHR)
Sensors built with a new manufacturing approach are capable of recording activity deep within the brain from large populations of individual neurons--with a resolution of as few as one or two neurons--in humans as well as a range of animal models, according to a study published in the Jan. 17, 2024 issue of the journal Nature Communications.
A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed. The research in mice finds that amnesia and poor memory following head injury is due to inadequate reactivation of neurons involved in forming memories.
Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other organelles generate energy, assemble new molecules and transport cargo. At Sanford Burnham Prebys, Feng will use cryo-EM to reveal new ways to stop or prevent cancers.
A major clinical trial has shown that by using MRI and tracking to guide the delivery of magnetic stimulation to the brains of people with severe depression, patients will see their symptoms ease for at least six months, which could vastly improve their quality of life.
Tactile mechanoreceptors are essential for environmental interaction and movement. Traditional tactile sensors in wearables and robotics often fall short, especially in restoring touch in cases of paralysis.
Neuroscientists from the University of Vienna and the Karolinska Institute in Stockholm have investigated whether playing violent video games leads to a reduction in human empathy.
There are approximately 72,967 neurosurgeons globally, representing a pooled density of 0.93 neurosurgeons per 100,000 individuals, and a median national density of 0.44 neurosurgeons per 100,000 individuals.
A study exploring the mechanisms behind why cognitive performance improves in response to exercise, has found that dopamine plays a key role.
Is it possible to amp up the energy production of mitochondria, the “power centers” of cells, without also boosting potentially harmful byproducts? If so, such a method could be used to treat a host of neurodegenerative diseases in which impaired mitochondria are believed to play a central role.
New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer’s disease, to a type of brain cancer known as glioma.
Larry Goldstein, M.D., chair of the University of Kentucky Department of Neurology, has been selected to serve as co-chair of The Kentucky Heart Disease and Stroke Prevention (KHDSP) Task Force representing stroke systems of care across the state.
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the first ALS care provider in the United States to offer patients a new interventional clinical study.
A new study has found that stress, through its propensity to drive up inflammation in the body, is linked to metabolic syndrome – leading researchers to suggest that cheap and relatively easy stress-management techniques may be one way to help improve biological health outcomes.
In an article just published in Physica A, researchers from Bar-Ilan University in Israel show how shallow learning mechanisms can compete with deep learning.
A study of mutant models of fragile X syndrome (FXS), a genetic disorder related to autism and intellectual disability, shows that activation of the cerebellum mitigates aberrant responses in sensory processing areas of the brain and improves neurodevelopmental behaviors. The findings, published by UT Southwestern Medical Center researchers in Cell Reports, could offer an opportunity for developing new therapies for neurocognitive disorders.
Glioblastoma, an incurable brain cancer, is characterized by cells that can mimic human neurons, even growing axons and making active connections with healthy brain neurons.
Certa manhã, bem cedo, enquanto examinava uma paciente adormecida no Centro de Medicina do Sono, o Dr. Erik St. Louis percebeu algo peculiar. A paciente, uma mulher na faixa dos 60 anos, começou a correr debaixo dos lençóis.
Una mañana temprano, mientras revisaba a una paciente dormida en el Centro de Medicina del Sueño, el Dr. Erik St. Louis observó algo particular. La paciente, una mujer de unos 60 años, había empezado a correr debajo de las sábanas. A media que sus párpados se agitaban, las piernas se pusieron en marcha, lentamente al principio, pero luego aceleraron rápidamente el paso, lo que la impulsó a lo largo de un camino que solo ella podía ver. Después de correr durante aproximadamente 30 segundos, se detuvo bruscamente y abrió los ojos. No era el comportamiento que el Dr. St. Louis esperaba de una persona con apnea del sueño.
مدينة روتشستر، ولاية مينيسوتا— يومًا ما في الصباح الباكر، أثناء فحص حالة نائمة في مركز طب النوم، لاحظ الدكتور إريك سانت لويس أمرًا غريبًا. حيث بدأت الحالة، وهي مريضة في أوائل الستينات من عمرها، تركض تحت غطاء سريرها. حيث بدأت ساقاها تنطلقان ببطء في البداية ثم أخذت تزيد سرعتها لتندفع في طريق لا يراه أحد غيرها، وكان جفناها يرتعشان في نفس الوقت. وبعد الركض لمدة حوالي 30 ثانية، توقفت فجأة وفتحت عينيها. ولم يتوقع الدكتور سانت لويس أن يصدر مثل هذا التصرف من مريض انقطاع النفس النومي.
Among the accomplishments of this year’s awardees are discoveries related to the role of altered pharmacokinetics in non-alcoholic fatty liver disease, the mechanisms of Parkinson’s disease neurodegeneration, the risk of COVID-19 to smokers and vapers, and the role of the microbiome in pregnancy and early developmental programming.
Researchers at the University of California San Diego have developed a neural implant that provides information about activity deep inside the brain while sitting on its surface.
Using advanced research techniques, Rutgers Heath–led scientists have shed light on how chronic fatigue syndrome and fibromyalgia are related, paving the way to even bigger breakthroughs.
Black people consistently had a higher rate of stroke than white people over a recent 22-year period, according to a study published in the January 10, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
New research led by the University of Bristol has explored the neuropsychological effects of rapid-acting antidepressants, including ketamine, scopolamine and psilocybin, and found that all three of these drugs can modulate affective biases associated with learning and memory.
Rice University scientists have developed a noninvasive way to monitor gene expression dynamics in the brain, making it easier to investigate brain development, cognitive function and neurological diseases, according to a study published in Nature Biotechnology.
Researchers at Dana-Farber Cancer Institute and the University of Trento, Italy, have developed a blood test, described in Cancer Discovery, that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma.
Leslie B. Vosshall, PhD, the Robin Chemers Neustein Professor of Neurogenetics and Behavior at The Rockefeller University, will receive the Perl-UNC Neuroscience Prize for her work on receptors that drive host-seeking behavior in the mosquito.
Obsessive-compulsive disorder (OCD),affecting 2-3% of the global population, manifests through distressing obsessions and compulsions.
Love is blind, the saying goes, and thanks to a new Australian study we are now a step closer to understanding why.
A new study from Washington University School of Medicine in St. Louis identifies, in mice, a critical communication pathway connecting the brain and the body’s fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
The research suggests an easy-to-measure brain process may be a target or biomarker in measuring treatment outcomes in clinical trials for patients with Batten disease.
Christian Nolen usually plays guitar on stage, but the professional guitarist recently underwent an open craniotomy and played notes from Deftones songs while a neurosurgical team worked to remove a tumor (glioma) from his brain. B-roll is available.
Sleep is a fundamental need, just like food or water. “You’ll die without it,” said Keith Hengen, an assistant professor of biology at Washington University in St. Louis. But what does sleep actually accomplish? For years, the best researchers could say is that sleep reduces sleepiness — hardly a satisfying explanation for a basic requirement of life.
About three years before he retired, David Campbell noticed something weird happening as he typed.
For military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions are a leading cause of post-traumatic stress disorder, anxiety, depression and suicide among veterans.
Differences in blood flow in the retina could explain why some migraine patients experience visual symptoms while others do not, according to UCLA study.
High levels of folic acid or vitamin B12 deficiency can affect fetal brain development in mice, according to a new study from researchers at the University of California, Davis.
Research tests a novel neurobiological model of how the brain acts as a psi (e.g. telepathy, clairvoyance, precognition, or mind-matter interactions) inhibitor and concludes that the frontal lobes of the brain act as a filter to inhibit humans' innate psi abilities.
In and out of the workplace, people often keep adverse information about themselves secret because they worry that others will judge them harshly. But those fears are overblown, according to new research from the McCombs School of Business.
The Wistar Institute is pleased to announce the recruitment of Filippo Veglia, Ph.D., to the Ellen and Ronald Caplan Cancer Center, where he joins Wistar’s Immunology, Microenvironment and Metastasis Program as an Assistant Professor.
A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease.
Diffuse gliomas are malignant brain tumors that cannot be optimally examined by means of conventional MRI imaging. So-called amino acid PET scans are better able to image the activity and spread of gliomas.
For children, the world is full of surprises. Adults, on the other hand, are much more difficult to surprise.
People who have more disrupted sleep in their 30s and 40s may be more likely to have memory and thinking problems a decade later, according to new research published in the January 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that sleep quality causes cognitive decline. It only shows an association.
Radon, a naturally occurring radioactive gas produced when metals like uranium or radium break down in rocks and soil, is a known cause of lung cancer. Now new research has found exposure to high levels of this indoor air pollutant is associated with an increased risk of another condition in middle age to older female participants with ischemic stroke.
Chronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to new research published in The Journal of Head Trauma Rehabilitation (JHTR), the official journal of the Brain Injury Association of America. The journal is published in the Lippincott portfolio by Wolters Kluwer.