Feature Channels: Heart Disease

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3-Apr-2018 9:05 AM EDT
Adult-like Human Heart Muscle Grown from Patient-specific Stem Cells
Columbia University School of Engineering and Applied Science

Researchers have developed a radically new approach to growing in the lab adult-like human heart muscle from human induced pluripotent stem cells in only four weeks. They compressed the development timeframe into a faster, more complete transition to cardiac maturity than any other team has done so far. They formed cardiac tissues from early-stage iPSC-derived cardiomyocytes, soon after the initiation of spontaneous contractions, by subjecting the cells encapsulated in hydrogel to increasingly intense physical conditioning.

Released: 4-Apr-2018 12:05 PM EDT
Bayshore Medical Center Now Offers Minimally Invasive Procedure to Deliver Chemotherapy Directly to a Tumor
Hackensack Meridian Health

Hackensack Meridian Health Bayshore Medical Center is proud to announce that it has expanded services to offer transcatheter arterial chemoembolization, also known as transarterial chemoembolization, or TACE. TACE is an image-guided, non-surgical procedure used to treat malignant lesions in the liver. Performed in the Interventional Radiology department, an X-ray guided catheter delivers chemotherapy medication and embolization materials into the blood vessels in the liver that lead to the tumor.

Released: 4-Apr-2018 9:00 AM EDT
Get Ready for Move More Month
Monday Campaigns

The American Heart Association will kick off Move More Month to rally everyone – individuals, friends and families, neighborhoods, communities, schools, and workplaces to join together and move for health, fun and togetherness. To keep up the momentum after Move More Month, the Monday Mile is a great way to kick off each week by moving and getting exercise. Some strategies for getting started with during Move More Month are included as well.

Released: 4-Apr-2018 8:05 AM EDT
New Study: Pecans Improved Certain Markers Related to Cardiometabolic Health in Overweight and Obese Adults
American Pecan Council

Eating a handful of pecans every day for four weeks improved certain markers of cardiometabolic disease risk, including insulin sensitivity, among a group of overweight and obese adults with excess abdominal fat, according to a new study.

Released: 4-Apr-2018 8:05 AM EDT
First Loretta Rogers Chair in Immunobioengineering to Study Heart from Unique Angle
University Health Network (UHN)

The Ted Rogers Centre for Heart Research today announces that Dr. Slava Epelman has accepted the brand new role of Loretta Rogers Chair in Immunobioengineering.

Released: 3-Apr-2018 2:05 PM EDT
New Weapon in Fight Against Dementia
University of Delaware

A University of Delaware researcher is investigating a novel compound's role in combating age-related chronic diseases like mild cognitive disorder and dementia. The study is funded by a grant from the National Institute on Aging.

Released: 2-Apr-2018 3:00 PM EDT
Reducing Odds of Hospital Readmissions with Better Transitions of Care
Thomas Jefferson University

Patients treated for heart attack were 48 percent less likely to have a sudden return to the hospital when educated using a multi-factored discharge and follow-up program

Released: 2-Apr-2018 9:05 AM EDT
People with Diabetes Visit the Dentist Less Frequently, Despite Link Between Diabetes and Oral Health Complications
New York University

Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University’s Brody School of Medicine.

Released: 28-Mar-2018 1:20 PM EDT
Largest-Ever Genetic Study of Stroke Provides New Insight Into the Disease
University of Maryland School of Medicine

An international research group studying 520,000 people from around the world has identified 22 new genetic risk factors for stroke, tripling the number of gene regions known to affect stroke risk. These results provide new clues on stroke mechanisms and could help scientists identify drug targets for treatment. The work is the largest genetic study on stroke ever.

Released: 28-Mar-2018 8:30 AM EDT
Highest Safety Rating Awarded to Cardiac Catheterization Laboratory at The Mount Sinai Hospital
Mount Sinai Health System

For 20 consecutive years, Mount Sinai holds "two-star" rating from New York State Department of Health for percutaneous coronary interventions

Released: 26-Mar-2018 9:05 AM EDT
Lung Transplant Drug Enters Human Testing After Decades of Work
University of Virginia Health System

The drug, regadenoson, is already commonly used to image cardiac patients’ hearts. But the UVA research suggests it could be put to another, lifesaving purpose.

16-Mar-2018 11:05 AM EDT
Boosting Enzyme May Help Improve Blood Flow, Fitness in Elderly
Perelman School of Medicine at the University of Pennsylvania

A well-studied enzyme called SIRT1 declines in the blood vessels with age and restoring it reverses the effects of vascular aging in mice. After receiving a supplement called NMN, older mice showed increased capillary density, blood flow, mobility, and endurance

15-Mar-2018 6:45 PM EDT
Scientists Pinpoint Cause of Vascular Aging in Mice
Harvard Medical School

-Scientists identify mechanism behind vascular aging, muscle demise in mice. -Treatment with chemical compounds reversed vascular aging, stimulated blood vessel growth and blood flow, boosted exercise capacity in aging animals. -Findings set the stage for therapies in humans to stave off a range of conditions linked to vascular aging.

Released: 22-Mar-2018 8:00 AM EDT
Technology, Expertise and Collaboration Are Key in Quality Cardiovascular Care
Atrium Health Wake Forest Baptist

People with heart and vascular conditions have benefited from technologies and treatments introduced in recent years. But traditional qualities such as expertise and teamwork are essential in making the most effective use of new products and procedures, says David Zhao, M.D., chief of cardiovascular medicine at Wake Forest Baptist Medical Center.

Released: 20-Mar-2018 6:05 PM EDT
Western Diet Depletes Artery-Protecting Immune Cells
La Jolla Institute for Immunology

New research from scientists at the La Jolla Institute for Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, which exacerbate atherosclerotic plaque buildup that occurs in cardiovascular disease. The team has also found that high density lipoproteins (HDL)—more commonly known as “good cholesterol”—counteract this process, helping the protective immune cells maintain their identity and keep arteries clear.

20-Mar-2018 8:45 AM EDT
Scott & White Medical Center Selected as Patient Navigator Program: Focus MI Diplomat Hospital
Baylor Scott and White Health

Scott & White Medical Center – Temple, part of Baylor Scott & White, is one of 15 U.S. hospitals selected to participate in the American College of Cardiology Patient Navigator Program: Focus MI Quality Campaign as a “Diplomat Hospital.” This is an expanded version of the original Patient Navigator Program launched in 2013. Scott & White – Temple was one of 35 pioneering hospitals chosen to provide personalized services to heart disease patients to help them avoid a quick return to the hospital.

19-Mar-2018 9:55 AM EDT
Limiting Work Shifts for Medical Trainees Affects Satisfaction, But Not Educational Outcomes
Johns Hopkins Medicine

Limiting first-year medical residents to 16-hour work shifts, compared to “flexing” them to allow for some longer shifts, generally makes residents more satisfied with their training and work-life balance, but their training directors more dissatisfied with curtailed educational opportunities. That’s one conclusion of a new study published online March 20 in the New England Journal of Medicine.

18-Mar-2018 1:45 PM EDT
Oral Micronized Progesterone May Decrease Perimenopausal Hot Flashes, Night Sweats
Endocrine Society

Oral micronized progesterone (OMP) may diminish hot flashes and night sweats in perimenopausal women, new research from Canada reports. The results will be presented on Monday, March 19 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

Released: 19-Mar-2018 1:05 PM EDT
Quintupling Inhaler Medication May Not Prevent Asthma Attacks in Children
Case Western Reserve University

Children with mild to moderate asthma do not benefit from a common practice of increasing their inhaled steroids at the first signs of an asthma exacerbation, according to clinical trial results published in The New England Journal of Medicine. Researchers found short-term increases in inhaled steroids did not prevent attacks in children aged 5 to 11, and may even slow a child’s growth.

Released: 19-Mar-2018 11:05 AM EDT
ProMedica, LISC Launch $45M Partnership
ProMedica

An Ohio integrated health system and a national social enterprise have announced a new alliance to mobilize tens of millions of dollars for underinvested communities—starting with a $45 million effort to scale up economic opportunity and improve health outcomes in Toledo and the surrounding region over the next decade.

15-Mar-2018 4:50 PM EDT
Frequent Glucose Monitoring Helps Prevent Hypoglycemia, Death in Hospitalized Heart Disease Patients
Endocrine Society

Hospitalized patients with stable coronary artery disease (CAD) may need frequent glucose monitoring to prevent hypoglycemia and death, new research reports. The results will be presented in a poster on Saturday, March 17 at ENDO 2018, the annual 100th meeting of the Endocrine Society in Chicago, Ill.

Released: 16-Mar-2018 2:55 PM EDT
Van Andel Research Institute Chief Scientific Officer Awarded Honorary Doctorate
Van Andel Institute

Van Andel Research Institute (VARI) Chief Scientific Officer Peter Jones, Ph.D., D.Sc., will be awarded an honorary doctorate from South Africa’s Stellenbosch University (SU) in recognition of a lifetime of scientific achievement and dedication to improving cancer treatment.

Released: 14-Mar-2018 3:40 PM EDT
Study Examines How Hospital Payments for Heart Attack Care May Affect Patient Outcomes
Beth Israel Lahey Health

A new, large-scale study – led by researchers at the Smith Center for Outcomes Research in Cardiology at Beth Israel Deaconess Medical Center (BIDMC) and published online today in Circulation: Cardiovascular Quality and Outcomes – examined the relationship between 30-day episode spending for inpatient and post-discharge care and patient mortality following a hospital admission for heart attack.

Released: 14-Mar-2018 3:30 PM EDT
CHOP Researchers Highlight Advances in Pediatric Heart Disease at American College of Cardiology 67th Annual Scientific Session & Expo 2018
Children's Hospital of Philadelphia

Physician-researchers from the Cardiac Center at Children’s Hospital of Philadelphia (CHOP) presented new findings on pediatric cardiovascular disease at the American College of Cardiology’s 67th Annual Scientific Session & Expo 2018 in Orlando, Fla. Among many abstracts presented were emergency department visits in patients with congenital heart disease, social risk factors for readmission, factors predicting mortality after prolonged critical illness and more.

Released: 13-Mar-2018 10:45 AM EDT
Testicular Cancer Survivors Need Adequate Screening for Long Term Heart Disease Risks
National Comprehensive Cancer Network® (NCCN®)

Largest study to date addressing the prevalence of metabolic abnormalities in testicular cancer survivors who received prior chemotherapy publishes findings in the latest issue of JNCCN

9-Mar-2018 3:05 PM EST
The Great Recession Took a Toll on Public Health, Study Finds
University of California, Los Angeles (UCLA), Health Sciences

The Great Recession, spanning 2008 to 2010, was associated with heightened cardiovascular risk factors, including increased blood pressure and glucose levels.The connections were especially pronounced among older homeowners and people still in the work force,

7-Mar-2018 10:05 AM EST
Genetic Heart Diseases Cause Fewer SIDS Deaths Than Previously Thought, Study Finds
Mayo Clinic

Genetic mutations linked to heart disease have been considered a leading cause of sudden infant death syndrome, but a new study by Mayo Clinic, British and Danish researchers finds they are to blame for far fewer SIDS deaths than previously thought. The findings are opening new lines of inquiry into possible causes of the syndrome and may help prevent unnecessary genetic testing of surviving family members. The study results appear in the Journal of the American College of Cardiology.

7-Mar-2018 6:05 AM EST
Study Links Type of Blood Pressure Medication to Increased Variability and Higher Risk of Death
Intermountain Medical Center

Two types of blood pressure medications — alpha blockers and alpha 2 agonist — show increased variability in blood pressure measurements between doctor visits, which is associated with an increased risk of death, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.

5-Mar-2018 7:00 AM EST
Testing for Calcium in the Coronary Arteries Provides a Better Way to Predict Heart Attack Events than Stress Testing Alone
Intermountain Medical Center

Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have found that incorporating underused, but available, imaging technologies more precisely predicts who’s at risk for heart attacks and similar threats — in time to prevent them.

7-Mar-2018 7:00 AM EST
Testing for Calcium in the Coronary Arteries Provides Better Way to Predict Heart Attack Events than Stress Testing Alone
Intermountain Medical Center

Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have found that incorporating underused, but available, imaging technologies, such as PET/CT scans, more precisely predicts who’s at risk for heart attacks and similar threats — in time to prevent them.

8-Mar-2018 8:15 AM EST
Stress of Open-Heart Surgery Significantly Reduces Patients’ Vitamin D Levels, But Supplementation Before and After Surgery Helps
Intermountain Medical Center

The stress of open-heart surgery significantly reduces patients’ vitamin D levels, but aggressive supplementation with vitamin D3, just before and after surgery, can completely eliminate the observed drop in vitamin D, researchers have found.

8-Mar-2018 2:45 PM EST
Barbershop-based Healthcare Study Successfully Lowers High Blood Pressure in African-American Men
Cedars-Sinai

African-American men successfully lowered their high blood pressure to healthy levels when aided by a pharmacist and their local barber, according to a new study from the Smidt Heart Institute.

6-Mar-2018 7:00 AM EST
Researchers Identify Proteins Associated with Diabetic Complications and Increased Heart Disease in Diabetic Patients
Intermountain Medical Center

Protein pathways that are closely linked to changes in both triglyceride and hemoglobin A1c levels in diabetic patients have been identified in new research by the Intermountain Medical Center Heart Institute in Salt Lake City.

7-Mar-2018 7:00 AM EST
Transcatheter Aortic Valve Replacement Dramatically Improves Heart Patients’ Quality of Life, Study Finds
Intermountain Medical Center

Patients who undergo a transcatheter aortic valve replacement, or TAVR — a minimally-invasive surgical procedure that repairs a damaged heart valve — experienced a significant increase in their quality of life, according to a new study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

Released: 11-Mar-2018 8:15 AM EDT
Eliminating Cost Barriers Helps Heart Patients Comply with Drug Regimens
Duke Health

Doctors often cite the high price of a prescription drug as a reason they don't prescribe it, while patients similarly say that cost is a main reason they quit taking a drug. Removing this financial barrier might increase the use of evidence-based therapies, improve patient adherence to those medications, and potentially save lives. That theory was tested in a study of heart attack survivors led by the Duke Clinical Research Institute; findings were presented March 11 at the American College of Cardiology annual scientific sessions meeting in Orlando.

11-Mar-2018 10:45 AM EDT
Study: Two Drugs Prevent Heart Problems in Breast Cancer Patients
University of Kentucky

Data presented from a Late-Breaking Clinical Trial has the potential to change the standard of care for HER2-positive breast cancer patients undergoing chemotherapy.

Released: 10-Mar-2018 12:15 PM EST
Precision Medicine: Access to Real-time Genetic Testing Data Impacts Prescriber Behavior following Minimally Invasive Stent Procedure
Perelman School of Medicine at the University of Pennsylvania

Today, in a late-breaking featured clinical research session at the American College of Cardiology Scientific Sessions 2018, researchers from Penn Medicine present first-of-its-kind data on the impact of real-time CYP2C19 genotype results when prescribing antiplatelet drugs in the clinic.

Released: 10-Mar-2018 12:15 PM EST
Non-Invasive Technology Is a Money-Saver for Heart Patients Needing PCI
Duke Health

Doctors evaluating patients for blockages in the heart are aided by having a good roadmap of the vascular terrain before they can insert stents to clear the impasse. Two technologies have been used with equal success, but now a study presented March 10 at the American College of Cardiology annual meeting by Duke cardiologists shows that the newer method carries a much lower cost, potentially saving each patient at least $800.

6-Mar-2018 9:45 AM EST
PET Myocardial Perfusion Imaging More Effective Than SPECT Scans In Detecting Coronary Artery Disease
Intermountain Medical Center

Patients who receive cardiac positron emission testing (PET) imaging instead of single photon emission computed tomography (SPECT) scan experienced a significant increase in the detection of severe obstructive coronary artery disease, according to researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

8-Mar-2018 2:15 PM EST
Heart Attack Protocol Can Improve Outcomes, Reduce Disparities Between Men and Women
Cleveland Clinic

ORLANDO: Cleveland Clinic researchers found that implementing a four-step protocol for the most severe type of heart attack not only improved outcomes and reduced mortality in both men and women, but eliminated or reduced the gender disparities in care and outcomes typically seen in this type of event. The research was presented at the American College of Cardiology’s 67th Annual Scientific Session and published in the Journal of the American College of Cardiology.

Released: 9-Mar-2018 11:45 AM EST
Bayshore Medical Center Regains Standard Operations
Hackensack Meridian Health

Hackensack Meridian Health Bayshore Medical Center has resumed normal operations, accepting all emergency patients into the Emergency Department and continuing regularly scheduled procedures in the wake of needed repairs after a small fire and water damage forced the temporary closure of a limited number of inpatient care areas on February 25. As a result, the hospital also elected to transport patients to nearby Hackensack Meridian Health hospitals and to divert ambulances.

6-Mar-2018 4:30 PM EST
When the Doctor’s Away
Harvard Medical School

Heart-attack sufferers who receive treatment during periods when interventional cardiologists are away at academic conferences are more likely to survive in the month after their heart attack than patients receiving treatment during nonmeeting days.

7-Mar-2018 1:00 AM EST
Renowned Cardiologist Says New Blood Pressure Guidelines Not Good for All
Houston Methodist

One of the nation’s leading cardiologists is challenging the new hypertension guidelines, perhaps sparing up to 10 million people from unnecessarily aggressive blood pressure treatments. His team’s study results appear March 7 in the Journal of the American College of Cardiology.

Released: 7-Mar-2018 11:05 AM EST
New Test Can Diagnose Heart Attack within an Hour
UC San Diego Health

UC San Diego Health is the first hospital in California to use the fifth generation troponin test to detect damage to the heart. The test was approved in the United States in 2017.

Released: 7-Mar-2018 8:05 AM EST
50-Year-Old Woman Thrives in Exercise Boot Camp, Refuses to Let Pacemaker Hold Her Back
Corewell Health

Julie Work always ate healthy and exercised regularly. Then, she passed out behind the wheel, went to a cardiologist and learned she needed a pacemaker. After recovery, she signed up for exercise boot camp and pushed herself to the limit. She needed to two pacemaker adjustments to keep up with her intense exercise regime.

Released: 6-Mar-2018 2:05 PM EST
Mouse Healing May Reveal Targets to Delay or Prevent Human Heart Failure
University of Alabama at Birmingham

A study of mouse healing after severe heart attacks focused on the heart and spleen, measuring types and numbers of immune cells; types and amounts of lipid signaling compounds; expression of enzymes that produce those signaling compounds; and which enzymes are key to resolution of inflammation.

5-Mar-2018 11:00 AM EST
Controlling Ceramides Could Help Treat Heart Disease
Sanford Burnham Prebys

SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today in Cell Reports, also identified several potential therapeutic targets that could prevent or reverse the effects of LCM.



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