Examining people across the spectrum of type 2 diabetes—from healthy to the full-blown disease—Joslin Diabetes Center scientists have found a molecular pathway that offers novel targets for drugs.
Latinos are twice as likely to develop diabetes as Caucasians, and half the Latinos born in the United States in this century are predicted to get the disease. Helping to meet this challenge, Joslin Diabetes Center’s Latino Diabetes Initiative—a comprehensive effort that combines clinical care, patient education, community outreach, research and healthcare team education—has upgraded its website with additional resources for Latinos with diabetes and their families in both English and Spanish.
Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) in individuals with type II diabetes, according to a study conducted by researchers in Chicago. The study indicates leptin resistance, a common characteristic of diabetes, may help prevent the formation of inflexible, fibrous tissue that develops in ALI and ARDS.
A new clinical trial at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is among the first to test surgery specifically for Type 2 diabetes. The aim of the study is to understand whether surgery can control diabetes, as well or even better than the best medical treatment available today. This is the first study of its kind open to patients who are overweight or mildly obese.
Researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego say that medication education is a key factor in helping patients with diabetes better stick to their drug treatments plans.
Researchers are reporting on a promising new approach to treating diabetic wounds, bed sores, chronic ulcers and other slow-to-heal wounds. It may be possible to speed healing by suppressing certain immune system cells.
Diabetes researchers at Washington University School of Medicine in St. Louis have identified a key mechanism that appears to contribute to the blood vessel damage that occurs in people with diabetes.
Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest.
Joslin Diabetes Center researchers have identified a key molecular player that contributes to the increased bleeding that hemorrhagic strokes may cause in people with diabetes.
Breast cancer patients are nearly 50 percent more likely to die of any cause if they also have diabetes, according to a comprehensive review of research conducted by Johns Hopkins physicians.
According to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), found higher Bisphenol A (BPA) levels in women with polycystic ovary syndrome (PCOS) compared to controls. Furthermore, researchers found a statistically significant positive association between male sex hormones and BPA in these women suggesting a potential role of BPA in ovarian dysfunction.
Approximately 19 million U.S. adults reported receiving treatment for diabetes in 2007, more than double the 9 million who said they received care in 1996.
Depression and diabetes appear to be associated with a significantly increased risk of death from heart disease and risk of death from all causes over a six-year period for women, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Patients with diabetes, kidney disease and anemia who don’t respond to treatment with an anti-anemia drug have a higher risk of cardiovascular disease or death, researchers at UT Southwestern Medical Center have found.
New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called “starvation hormone” affects multiple biological systems, including preventing insulin sensitivity and promoting cell survival.
City Tech Nursing Prof. Kathleen Falk's research indicates that a community-based care plan and regular disease marker monitoring made a difference in health outcomes in patients with obstacles to diabetes management.
In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the fact that we no longer live in the Stone Age.
A myriad of inputs can indicate a body’s health bombard pancreatic beta cells continuously, and these cells must consider all signals and “decide” when and how much insulin to release to maintain balance in blood sugar, for example. Reporting in Nature Chemical Biology last month, researchers at the Johns Hopkins University School of Medicine have teased out how these cells interpret incoming signals and find that three proteins relay signals similar to an electrical circuit.
A La Jolla Institute team, led by leading type 1 diabetes researcher Matthias von Herrath, M.D., has demonstrated the effectiveness of a recently developed computer model in predicting key information about nasal insulin treatment regimens in type 1 (juvenile) diabetes. Development of the software, the Type 1 Diabetes PhysioLab® Platform, was funded through the peer-reviewed grant program of the American Diabetes Association.
Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded $600,000 from the American Diabetes Association (ADA) to study the effect of resveratrol, a chemical compound most notably found in red wine and grapes, on impaired glucose tolerance (IGT) in older adults. IGT occurs when blood glucose levels are higher than normal, but not high enough to be considered diabetes. The condition is also known as prediabetes.
For patients living with diabetes, reducing the amount of salt in their daily diet is key to warding off serious threats to their health, a new review of studies finds.
A new study finds that combining the newer diabetes drug exenatide with insulin provides better blood sugar control in patients with type 2 diabetes than insulin alone and helps promote weight loss.
Temple University students create a YouTube channel called Diabetes Diaries, where people with diabetes, or friends and family members of diabetics, can upload videos to tell their stories.
Sally Pinkstaff, M.D., Ph.D., F.A.C.E., F.A.C.P., an endocrinologist at Sinai Hospital of Baltimore, is available as an expert on diabetes- how it can be prevented and how it is treated.
Two studies from the Childhood Obesity Research Center at the Keck School of Medicine of the University of Southern California (USC) have found evidence that Hispanic children and adolescents are genetically predisposed to developing fatty liver disease—a condition that can lead to cirrhosis, cardiovascular disease and diabetes.
Diabetes expert Dr. Deneen Vojta, MD, co-creator of Unitedhealth Group’s Diabetes Prevention and Control Alliance, is available for interviews throughout National Diabetes Awareness Month.
New findings by researchers at UT Southwestern Medical Center suggest that serotonin – a brain chemical known to help regulate emotion, mood and sleep – might also have anti-diabetic properties.
Physicians, nurses and other health care providers can have some of the most up-to-date information on the growing diabetes epidemic at their fingertips, thanks to the release of a new Johns Hopkins guide to the disease now available on all smart phone devices.
A new study of nearly 70,000 women found a clear association between abuse in childhood and adolescence and the risk of type 2 diabetes in adult women.
A donation from the Thomas J. Beatson, Jr. Foundation will broaden access to Joslin's care ambassadors program for youth newly diagnosed with diabetes.
A fatal genetic disorder that frequently takes years to diagnose may soon be detectable with a simple blood test. For patients with Niemann-Pick type C disease, the test will make it possible to begin treatment earlier, when it is more likely to improve quality of life and to further extend lives.
Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly interacts with macrophages, promoting an inflammatory response that can lead to insulin resistance and diabetes.
A University at Buffalo endocrinologist has received a three-year $400,000 Junior Faculty Award from the American Diabetes Society to study the effects of low testosterone levels in young men with type 2 diabetes.
New findings by UT Southwestern Medical Center researchers suggest a novel role for the brain in mediating beneficial actions of the hormone leptin in type 1 diabetes.
Phone calls with a peer facing the same self-management challenges helped diabetes patients manage their conditions and improved their blood sugar levels better than those who used traditional nurse care management alone.
Mount Sinai School of Medicine researchers have found that a gene associated with the onset of Type 2 diabetes also is found at lower-than-normal levels in people with Alzheimer’s disease.
University of Michigan scientists have identified events inside pancreatic cells that set the stage for a neonatal form of non-autoimmune Type 1 diabetes, and may play a role in Type 2 diabetes.
A rapid increase in the number of hospitalizations due to diabetes for young adults – particularly young women – echoes the dramatic increase in rates of obesity across the United States in the last 30 years, according to a U-M study published in Journal of Women’s Health.
A clinical trial at UT Southwestern Medical Center aims to determine whether adding the hormone leptin to standard insulin therapy might help rein in the tumultuous blood-sugar levels of people with type 1 (insulin-dependent) diabetes.
Maike Sander, MD, associate professor of pediatrics and cellular & molecular medicine at the University of California, San Diego School of Medicine has been awarded nearly $5 million by the Beta Cell Biology Consortium (BCBC) to lead an interdisciplinary team in cell therapy research for type 1 diabetes.