Feature Channels: Digestive Disorders

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Released: 12-Jun-2018 2:05 PM EDT
New Cell Transplant Program, One of Few in the Country, Giving Pancreatitis Patients a Better Option
University of North Carolina Health Care System

The Chronic Pancreatitis and Autologous Islet Cell Transplant Program, created by Chirag S. Desai, MD, is helping patients improve their quality of life by eliminating severe pain and reducing or ending the use of narcotic pain medications, while preventing brittle diabetes.

4-Jun-2018 8:00 AM EDT
Scientists Identify Foods that Fight Disease
American Society for Nutrition (ASN)

Nutrition 2018 will feature the latest research into how adding certain foods to our diet might help lower risk for diabetes, cancer, neurodegenerative diseases and other health issues.

4-Jun-2018 8:00 AM EDT
Childhood Obesity: Insights on Risk Factors and Prevention
American Society for Nutrition (ASN)

The factors that contribute to overweight and obesity are complex, but one pattern is clear: having obesity during childhood increases the likelihood of having obesity as an adult. The Nutrition 2018 meeting will feature new research on factors that may contribute to childhood obesity, as well as factors that can help kids maintain a healthy weight.

4-Jun-2018 8:00 AM EDT
The Latest Science on Breastfeeding
American Society for Nutrition (ASN)

Guidelines recommend breastfeeding as the best source of nutrition for most babies. The Nutrition 2018 meeting will feature new research findings on the nature of breast milk and how breastfeeding may affect the health of both moms and babies.

7-Jun-2018 9:00 AM EDT
MD Anderson announces 2018 Andrew Sabin Family Fellows
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center has named eight researchers to the third annual class of Andrew Sabin Family Fellows. As part of the Andrew Sabin Family Fellowship Program, each researcher will receive $100,000 in funding over two years. The Andrew Sabin Family Foundation established the program through a $30 million endowment to encourage creativity, innovation and highly impactful cancer research in four categories: basic science, clinical, physician-scientist, and population and quantitative science.

Released: 6-Jun-2018 2:30 AM EDT
Investigadores de Mayo Clinic avanzan en elaboración de análisis de ADN para cáncer de hígado
Mayo Clinic

Un grupo de investigadores de Mayo Clinic y Exact Sciences Corporation terminaron un estudio de fase II para comparar un conjunto de marcadores del ADN frente a la alfafetoproteína, como método para analizar el cáncer de hígado.

Released: 5-Jun-2018 5:05 PM EDT
Pesquisadores da Mayo Clinic estão mais próximos de desenvolver um teste de DNA para o câncer de fígado
Mayo Clinic

Um grupo de pesquisadores da Mayo Clinic e da Exact Sciences Corporation concluiu um estudo de fase II que realizou uma comparação entre um conjunto de marcadores de DNA e a alfafetoproteína como método para testar o câncer de fígado. Os pesquisadores apresentaram suas conclusões na conferência Digestive Disease Week (Semana das doenças digestivas) de 2018, em Washington, D.C.

Released: 5-Jun-2018 5:05 PM EDT
Mayo Clinic的研究人员在开发肝癌DNA测试上更近了一步
Mayo Clinic

来自Mayo Clinic和Exact Sciences Corporation的一组研究人员已经完成了一项II期研究,将一组DNA标记物作为一种检测肝癌(liver cancer)的方法与甲胎蛋白进行了比较。 研究人员在华盛顿特区举行的2018年消化疾病周(Digestive Disease Week)会议上介绍了他们的发现。

Released: 5-Jun-2018 12:05 PM EDT
Cedars-Sinai Research Identifies Gut Gas Linked to Diarrhea
Cedars-Sinai

Cedars-Sinai investigators have for the first time identified a gas produced in gut that could improve the diagnosis and treatment of patients with two common intestinal illnesses—small intestine bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS).

Released: 5-Jun-2018 10:45 AM EDT
Exploring Targeted Second-Line Therapy for Advanced Colorectal Cancer
Rutgers Cancer Institute of New Jersey

Targeted therapy with anti-VEGF and anti-EGFR antibodies both improve outcomes when added to chemotherapy in the treatment of colorectal cancer. However, some previous studies suggested the combination of the two antibodies may have a negative interaction. Those studies were done without selecting patients for KRAS mutations. Investigators from the ECOG-ACRIN Cancer Research Group led by Howard S. Hochster, MD, FACP, associate director for clinical research and director of gastrointestinal oncology at Rutgers Cancer Institute of New Jersey, explored the anti-VEGFR antibody ramucirumab in second-line treatment.

5-Jun-2018 9:00 AM EDT
Penn Medicine Gastrointestinal Bleeding Research Points to Need for Updated Medicare Policies
Perelman School of Medicine at the University of Pennsylvania

Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with gastrointestinal bleeding following an evaluation of patients with the condition.

Released: 4-Jun-2018 6:05 PM EDT
Research Scientist Scores Induction Into Women’s Basketball Hall of Fame
Cedars-Sinai

For 19 years, Lisa Thomas, former professional basketball player and Cedars-Sinai laboratory investigator of inflammatory bowel disorders and immunobiology, thought her glory days as a forward and center for collegiate and professional teams were behind her. And then she got a phone call that returned her to the hardwood courts of her youth. On June 9, Thomas will be one of 96 players from the now-defunct Women’s Professional Basketball League to be inducted as “Trailblazers” into The Women’s Basketball Hall of Fame.

Released: 4-Jun-2018 2:05 PM EDT
Experimental drug restores some bladder function after spinal cord injury, study finds
Ohio State University

An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function, new research suggests.

Released: 4-Jun-2018 12:05 PM EDT
Epitope Diagnostics, Inc. Introduces New 2-Hour Human ACTH ELISA Kit
70th AACC Annual Scientific Meeting Press Program

Epitope Diagnostics is proud to introduce a new adrenocortocotropic hormone (ACTH) ELISA Kit, which measures ACTH levels with high sensitivity and robust assay performance characteristics.

Released: 4-Jun-2018 10:20 AM EDT
Researchers discover how colon cancer mutates to escape the immune system
University of California, Los Angeles (UCLA), Health Sciences

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

Released: 2-Jun-2018 11:05 AM EDT
New Treatment Combination Improves Outcomes for Some Patients with Colorectal Cancer
Roswell Park Comprehensive Cancer Center

Research to be presented at the ASCO 2018 Annual Meeting suggests that a new treatment combination can extend survival for many patients with advanced colorectal cancer and that its efficacy compares favorably to single-agent approaches.

2-Jun-2018 8:00 AM EDT
Genomic Markers Can Predict the Presence of Lynch Syndrome across a Broad Spectrum of Cancers
Memorial Sloan Kettering Cancer Center

Microsatellite instability (MSI) and DNA mismatch repair (MMR) deficiencies can predict Lynch syndrome (LS) across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center (MSK), who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology. This finding suggests that LS is linked to more types of cancer than previously thought, prompting a call for germline testing for LS in all individuals with MSI-high (MSI-H)/mismatch repair deficient (MMR-D) tumors.

Released: 1-Jun-2018 3:40 PM EDT
Digestive Disease Week 2018: NewYork-Presbyterian Experts Available for Interview
New York-Presbyterian Hospital

Experts are available for online, print and broadcast interviews.

Released: 1-Jun-2018 9:05 AM EDT
Anti-cancer agent Ciclopirox Prodrug’s first-in-human Clinical Trial to be presented at ASCO 2018
University of Kansas Cancer Center

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago.

Released: 31-May-2018 8:00 AM EDT
Infection Rates After Colonoscopy, Endoscopy at US Specialty Centers Are Far Higher Than Previously Thought
Johns Hopkins Medicine

The rates of infection following colonoscopies and upper-GI endoscopies performed at U.S. outpatient specialty centers are far higher than previously believed, according to a Johns Hopkins study published online this month in the journal Gut.

Released: 30-May-2018 3:30 PM EDT
Virtual Colonoscopy Can Attract Younger Americans to Follow New ACS Colorectal Cancer Screening Guidelines
American College of Radiology (ACR)

Virtual colonoscopy (CT Colonography) — shown to increase colorectal cancer screening rates at a lower cost than standard colonoscopy — can help jump-start the transition to screening Americans starting at age 45 as new American Cancer Society Screening guidelines recommend.

Released: 30-May-2018 1:05 PM EDT
Northwestern Medicines's Chief of Gastrointestinal Surgery available to comment on Colon Cancer Screening Recommendation Change
Northwestern Medicine

The American Cancer Society this week changed its advice on getting screen for colorectal cancer and is recommending that screening start five years earlier, from age 50 to age 45.

Released: 30-May-2018 11:05 AM EDT
As Colorectal Cancer Rises in Young People, New Guidelines Recommend Screening Start at 45
University of Colorado Cancer Center

Study published today the journal Cancer recommends colorectal cancer screening start at age 45, five years younger than currently recommended for both men and women of all races and ethnicities.

24-May-2018 6:00 PM EDT
Study Suggests Obese Children Who Drink Recommended Amount of Milk Have Less Risk of Metabolic Syndrome
University of Texas Health Science Center at Houston

Obese children who consume at least two servings of any type of cow’s milk daily are more likely to have lower fasting insulin, indicating better blood sugar control, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

Released: 24-May-2018 10:05 AM EDT
New Jersey Health Care Providers, Community Members, and Researchers Come together to Address Disparities and Improve Screening Opportunities for Colorectal and Lung Cancers
Rutgers Cancer Institute of New Jersey

Health care providers, community members, and researchers from across New Jersey came together at the ‘Conference for Change’ event, hosted by the New Jersey Primary Care Association and sponsored by ScreenNJ to address the need to improve screening rates for colorectal and lung cancers.

Released: 23-May-2018 1:40 PM EDT
Wolters Kluwer and American College of Gastroenterology Announce Publishing Partnership
Wolters Kluwer Health: Lippincott

Wolters Kluwer Health announced today a publishing partnership with the American College of Gastroenterology (ACG) that adds three titles to the Lippincott portfolio. Beginning in January 2019, Wolters Kluwer will publish ACG’s flagship scientific publication, The American Journal of Gastroenterology, as well as two additional official publications, Clinical and Translational Gastroenterology (CTG) and ACG Case Reports Journal.

22-May-2018 10:05 AM EDT
Surveillance Intensity Not Associated with Earlier Detection of Recurrence or Improved Survival in Colorectal Cancer Patients
University of Texas MD Anderson Cancer Center

A national retrospective study led by researchers at The University of Texas MD Anderson Cancer Center found no association between intensity of post-treatment surveillance and detection of recurrence or overall survival (OS) in patients with stage I, II or III colorectal cancer (CRC). Published in the Journal of the American Medical Association, the study is the largest of surveillance intensity in CRC ever conducted.

Released: 17-May-2018 1:05 PM EDT
Fight Colorectal Cancer Advocate Walking 2,800 Miles Across the U.S. To Raise Awareness of Preventable Disease
Fight Colorectal Cancer

Chad Schrack, a Fight Colorectal Cancer advocate is walking from Washington, D.C. to Venice Beach, California to honor his wife, a colorectal cancer survivor and all those affected by the second-leading cancer killer in the U.S.

Released: 17-May-2018 1:05 PM EDT
New Blood Test Rapidly Detects Signs of Pancreatic Cancer
University of California San Diego

UC San Diego researchers have developed a test that can screen for pancreatic cancer in just a drop of blood. The test, which is at the proof-of-concept stage, provides results in under an hour. It's simple: apply a drop of blood on a small electronic chip, turn the current on, wait several minutes, add fluorescent labels and look at the results under a microscope. If a blood sample tests positive for pancreatic cancer, bright fluorescent circles will appear.

   
Released: 17-May-2018 12:05 PM EDT
Northwestern Medicine Expert Available to Comment on First Non-Opioid to Treat Withdrawal Symptoms
Northwestern Medicine

The U.S. Food and Drug Administration has approved the first non-opioid treatment to ease sudden withdrawal from opioids. Lucemyra was approved for up to 14 days of treatment for adults to ease common withdrawal symptoms like vomiting, diarrhea, muscle pain and agitation.

Released: 17-May-2018 12:05 PM EDT
Polly’s Run Races Against Pancreatic Cancer
University of New Mexico Comprehensive Cancer Center

Polly’s Run, a fundraiser to support pancreatic cancer research, will take place Sunday, June 3, at Tiguex Park near Albuquerque’s Old Town. The event will feature a 5K run/walk that starts at 8:30 a.m. and a Kid’s K that starts at 9:30 a.m. All proceeds benefit the Polly Rogers Pancreatic Cancer Research Fund at The University of New Mexico Comprehensive Cancer Center.

Released: 17-May-2018 10:05 AM EDT
Ovarian Cancer Drug Shows Promise in Pancreatic Cancer Patients with BRCA Mutation
Perelman School of Medicine at the University of Pennsylvania

A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. An international team of researchers led by the Perelman School of Medicine and the Basser Center for BRCA at the University of Pennsylvania reported their findings this week in JCO Precision Oncology.

14-May-2018 1:05 PM EDT
Under Certain Conditions, Bacterial Signals Set the Stage for Leukemia
University of Chicago Medical Center

A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.

Released: 16-May-2018 12:05 PM EDT
Colon Cancer Cells Use Mysterious RNA Strands to Avoid Cell Death
Case Western Reserve University

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other RNAs, the intriguing strands do not appear to encode proteins and are termed “long non-coding RNAs” or “lincRNAs.”A new study showed some lincRNAs could be targeted by drug developers to halt colon cancer.

Released: 14-May-2018 5:05 PM EDT
Genetic Fixer-Uppers May Help Predict Bladder Cancer Prognosis
Penn State Health

Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers.

9-May-2018 2:45 PM EDT
Deadly Cancers Show Early, Detectable Differences From Benign Tumors
Duke Health

Do metastatic cancer tumors "break bad" or are they "born bad"? In a study publishing the week of May 14 scientists found that in the colorectal tumors they examined, invasive cancers are born to be bad, and this tendency can potentially be identified at early diagnosis.

Released: 11-May-2018 12:05 PM EDT
Exploring the Connection Between Diet, Gut Microbes and Cognitive Decline
RUSH

Are abnormal intestinal microorganisms a risk factor for developing cognitive impairment? Researchers at Rush University Medical Center are trying to answer that question with a new study that will explore how the intestinal microbiota – the bacteria in the intestine –influence the progression of cognitive decline and the development of Alzheimer’s disease.

Released: 11-May-2018 4:05 AM EDT
Queen's University Researchers in Collaboration to Develop a New Treatment for Pancreatic Cancer
Queen's University Belfast

Queen’s University Belfast researchers at the Centre for Cancer Research and Cell Biology (CCRCB) alongside local company Fusion Antibodies plc have secured a prestigious Medical Research Council (MRC) award to develop a new antibody drug for the treatment of pancreatic cancer.

   
Released: 8-May-2018 2:15 PM EDT
New Research: Some Gut Bacteria May Protect Against Intestinal Infection
University of Maryland School of Medicine

Scientists have for the first time found evidence that a microbe in the human gut is associated with protection from typhoid fever infection. If the research is borne out, it could offer an exciting new way to reduce these infections.

2-May-2018 11:30 AM EDT
Tissue Engineered Human Pancreas Cells Successfully Treat Diabetic Mice
Cincinnati Children's Hospital Medical Center

Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice. In a study published by Cell Reports, the scientists use a new bioengineering process they developed called a self-condensation cell culture. The technology helps nudge medical science closer to one day growing human organ tissues from a person’s own cells for regenerative therapy

Released: 7-May-2018 12:30 PM EDT
Study Confirms Curable State Between Single and Widespread Cancers
University of Chicago Medical Center

Using molecular determinants combined with clinical data, UChicago physicians confirm their oligometastasis hypothesis in colorectal cancers with limited spread of disease to the liver.

3-May-2018 2:05 PM EDT
Preclinical MD Anderson Study Suggests ARID1a May Be Useful Biomarker for Immunotherapy
University of Texas MD Anderson Cancer Center

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center. The preclinical study suggests that mutations in ARID1a could be beneficial in predicting immunotherapy success.

Released: 7-May-2018 10:00 AM EDT
Review of Nearly 500 Patient Cases Shows Benefits of Surgery for Congenital Hyperinsulinism
Children's Hospital of Philadelphia

A review of nearly 500 cases of infants with severe congenital hyperinsulinism who underwent partial or near-total removal of their pancreas for persistent hypoglycemia at Children’s Hospital of Philadelphia (CHOP) showed that surgeons can cure virtually all patients with the focal, or localized, form of the rare genetic disease.

Released: 1-May-2018 11:50 AM EDT
Florida Cancer Centers Awarded $1.36 Million to Fight Pancreatic Cancer
Moffitt Cancer Center

The Florida Department of Health’s James and Esther King Biomedical Research Program has armed Moffitt Cancer Center, University of Florida (UF) Health Cancer Center – Gainesville, Sylvester Comprehensive Cancer Center at the University of Miami and numerous collaborating centers with $1.36 million to address cancer disparities and improve outcomes and care for individuals affected by pancreatic cancer.

Released: 1-May-2018 8:05 AM EDT
CAR-T Immunotherapy Eliminates Metastatic Colorectal Cancer in Mice
Thomas Jefferson University

A CAR-T-based immunotherapy successfully kills tumors and prevents metastatic growth, in final preclinical tests before human trials.

16-Apr-2018 6:00 PM EDT
Drinking Kefir May Prompt Brain-Gut Communication to Lower Blood Pressure
American Physiological Society (APS)

Drinking kefir may have a positive effect on blood pressure by promoting communication between the gut and brain. Kefir is a fermented probiotic milk beverage known to help maintain the balance of beneficial bacteria in the digestive system. Researchers will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego.



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