Treatment with biologics does not increase the risk of a second malignancy in rheumatoid arthritis patients who have a history of cancer, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting.
Compared to controls, patients with psoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid arthritis – two autoimmune diseases often treated with similar drugs that can cause liver damage.
For patients with osteoarthritis of the knee, a minimally invasive procedure called cooled radiofrequency ablation (CRFA) provides better pain reduction and functional improvement compared to steroid injection of the knee, concludes a study in Regional Anesthesia & Pain Medicine, published by Wolters Kluwer.
A Montreal Clinical Research Institute discovery sheds light on osteocalcin, a hormone produced by our bones that affects how we metabolize sugar and fat.
Senior Nicholas Bieno is teaming up with Professor of Engineering Brian Johns to create a virtual reality surgical simulator for a procedure that repairs hip fractures.
According to research published in Regional Anesthesia and Pain Medicine, using more than one type of pain medicine to target different pain pathways has been shown to decrease pain while reducing side effects of knee replacement surgery.
For younger patients with severe damage to the rotator cuff muscles, a "reverse" shoulder replacement provides lasting improvement in shoulder function, according to a study in The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
A research participant at the University of Louisville with a complete spinal cord injury, who had lost motor function below the level of the injury, has regained the ability to move his legs voluntarily and stand six years after his injury.
A new class of drugs for blood cancers such as leukemia and multiple myeloma is showing promise. But it is hobbled by a problem that also plagues other cancer drugs: targeted cells can develop resistance. Now scientists, reporting in ACS Central Science, have found that insights into a rare genetic disease known as NGLY1 deficiency could help scientists understand how that resistance works — and potentially how drugs can outsmart it.
Think the shorter winter days, ice and snow put your older loved one at greater risk for a fall and broken hip? Think again. A preliminary study presented at the ANESTHESIOLOGY® 2017 annual meeting shows that the majority of falls occur during warm months, and a greater number of the falls happen indoors rather than out.
A new five-year study of nearly 1,600 patients finds that genetic testing can help determine the safest dose of the blood thinner warfarin, with fewer side effects, in patients undergoing joint replacement surgery.
NewYork-Presbyterian will hold a dedication ceremony today to celebrate the renaming of The Spine Hospital to the Daniel and Jane Och Spine Hospital at NewYork-Presbyterian, in recognition of the visionary $25 million gift by longtime supporters Daniel and Jane Och.
A team of neuroscientists has uncovered a neural network that can restore diaphragm function after spinal cord injury. The network allows the diaphragm to contract without input from the brain, which could help paralyzed spinal cord injury patients breathe without a respirator.
Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a study from McMaster University's Stem Cell and Cancer Research Institute and published in Nature Cell Biology.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.
Results of a University of Nebraska Medical Center study published in the Oct. 10 issue of PLOS ONE, found if the standard supplementation of 400 IUs of vitamin D is increased to 800 IUs daily there are reductions in the number of premature and preterm babies with extremely low bone density.
Surgeons at The Johns Hopkins Hospital have for the first time used a real-time, image-guided robot to insert screws into a patient’s spine. With last week’s surgery, Johns Hopkins joins the growing number of hospitals in the United States that offer robotic-assisted spine surgery.
About 850 people worldwide have been diagnosed with FOP in the last five decades. Contrast that to the fewer than 100 individuals with POH who have been identified around the world. POH is usually first noticed in babies with the appearance of small “rice-grain” particles of bone under the skin. The bone continues to grow deeper in the first layer of fat next to skin cells and progresses deeper into connective tissue such as skeletal muscle and joints.
The Hackensack University Medical Center Foundation has received a substantial donation from Celgene Corporation to advance multiple myeloma research and transformational medicine that improve patient outcomes at Hackensack Meridian Health - John Theurer Cancer Center. Supported by Celgene, a global biopharmaceutical leader in the discovery, development and delivery of treatment for diseases like multiple myeloma (MM), funds will help to establish the Multiple Myeloma Institute (MMI) – a leading-edge research facility at the Seton Hall-Hackensack Meridian School of Medicine scheduled to open in 2018.
Rowan University School of Osteopathic Medicine has been awarded the first of a five-year grant from the U.S. Department of Health and Human Services to administer three Area Health Education Center programs. When completed, funding for the award will exceed $1.5 million.
One out of every 25 children will develop scoliosis, or curvature of the spine. While some are babies or toddlers when diagnosed, most cases occur during the pre-teen years.
ProMedica Toledo Hospital is the first in Ohio to acquire BrightMatter™ technology, an innovative solution that combines advanced imaging, planning, navigation and robotics for complex brain tumor and spinal surgery.
A study is testing whether a pressure-detecting shoe insole can help people with knee osteoarthritis walk in a way that reduces knee strain
Elementary school children with craniofacial anomalies show the highest levels of anxiety, depression and difficulties in peer interactions when compared to youths with craniofacial defects in middle and high schools. The findings suggest that keeping a close watch for these signs and educating the child’s peers about their condition may be necessary for this age group.
Karun Sharma, MD, PhD, Director of Interventional Radiology, and colleagues at Sheikh Zayed Institute for Pediatric Surgical Innovation at Children’s National Health System in Washington, DC, have completed their clinical trial to treat benign but painful bone tumors (osteoid osteoma) in children.
A new study finds that genetic testing can help determine the safest dose of the blood thinner warfarin, with fewer side effects, in patients undergoing joint replacement surgery.
Physician and healthcare professional advocates from the American College of Rheumatology (ACR) are joined by rheumatology patients on Capitol Hill this week to urge lawmakers to address the significant drug cost and access issues affecting millions of Americans living with arthritis and other rheumatologic diseases.
Nova Southeastern University (NSU) announces the largest philanthropic gift in its history from Tampa-area cardiologist Dr. Kiran C. Patel and his wife, pediatrician Dr. Pallavi Patel. The commitment will significantly expand its programs in osteopathic medicine and health care sciences, and be used to develop a new 27-acre campus for NSU in Clearwater, Fla.
A major health problem in older people is age-associated osteoporosis — the thinning of bone and the loss of bone density that increases the risk of fractures. Researchers have now detailed an underlying mechanism leading to that osteoporosis.
Patients with "metal on metal" (MoM) artificial hips are at risk of complications caused by adverse reactions to metal debris (ARMD). A study in the September 20, 2017 issue of The Journal of Bone & Joint Surgery confirms that blood metal .
Vanderbilt’s Scott Arthur, M.D., recently performed the state’s first knee surgery using a newly approved implant containing a patient’s regrown cartilage cells.
About two-thirds of U.S. adults will struggle with low back pain during their lifetime. ReActiv8 is a surgically-implanted device that delivers mild electrical stimulation to nerves in key lower back muscles. Unlike other nerve treatments, ReActiv8 does not mask a patient’s pain.
A study by researchers at Hospital for Special Surgery and Harvard Medical School suggests new guidelines may be in order for evaluating and treating lower extremity pain. They found a significant association between foot pain and knee or hip pain.
The Endocrine Society today announced it has selected 14 leaders in the endocrinology field as winners of its prestigious 2018 Laureate Awards.
Nearly 282,000 people in the U.S. live with paralysis following a spinal cord injury (SCI). A review of more than 90 studies found that electrical stimulation may help restore function in those paralyzed after SCI. The article is published in Physiology.
The Keck School of Medicine of USC is one of three institutions to share a highly competitive Cyber-Physical Systems Frontier grant to develop a brain-computer interface to restore walking and lower extremity sensation for people with paraplegia
Alina Franke registered to donate her bone marrow in Hamburg, Germany, in 2009. She wound up being the one person in 24 million around the world on the Be The Match registry to be the perfect match that Jimmy Roberson needed.
A new drug that boosts bone formation has been shown to reduce the risk of fracture in women with osteoporosis when compared to one of the most commonly used osteoporosis medications, according to findings from UAB reported online in NEJM.
Before the Cartiva implant was available, individuals who experienced severe toe pain from arthritis had no options for relieving the pain that would allow them to remain active.
Researchers in Germany have demonstrated that hematopoietic stem cell (HSC) transplants can be improved by treatments that temporarily prevent the stem cells from dying. The approach, which is described in a paper to be published September 7 in The Journal of Experimental Medicine, could allow those in need of such transplants, including leukemia and lymphoma patients, to be treated with fewer donor stem cells while limiting potential adverse side effects.
The United States’ National Institutes of Health (NIH) has awarded New York Institute of Technology (NYIT) Professor of Life Sciences Michael Hadjiargyrou, Ph.D., a multi-year grant to study a newly discovered musculoskeletal specific gene, Mustn1, and to determine its role in cartilage regeneration and skeletal repair. Hadjiargyrou’s research will also begin to elucidate a new and as yet uncharacterized protein family important for cartilage and bone biology.
After a spinal cord injury, a significant amount of secondary nerve damage is caused by inflammation and internal scarring that inhibits the ability of the nervous system to repair itself.
Balancing school and sleep; Researchers report link between cells associated with aging and bone loss; Discovery of new prostate cancer biomarkers could improve precision therapy...
Scientists at Children’s Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease. HME causes multiple, disabling bone outgrowths (called exostoses or osteochondromas) and skeletal deformities, and such drugs could potentially spare patients the prospect of numerous, sometimes difficult childhood surgeries, while also reducing their risk of cancer.
More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting.
Doctors believe there is some good to be found in nicotine, the highly addictive drug in tobacco products. Lung experts at The Ohio State University Wexner Medical Center are testing whether nicotine can help people with a chronic inflammatory lung disease called sarcoidosis.
An exploration of the latest understanding of the complex mechanisms behind OA pain offers new possibilities and potential treatment targets for osteoarthritis (OA) pain. New areas of research discussed include the use of combination therapies and the development of biomarkers to target effective pain treatment.
“Expanding our patients’ access to safe, effective, and affordable biologic and biosimilar therapies is a top priority of the rheumatology community. Therefore, the American College of Rheumatology applauds new legislative and regulatory developments that will expedite the approval of new therapies, increase competition, and lower the cost of these drugs.
A study led by a biomedical researcher at Iowa State University found that a potential treatment for spinal muscular atrophy, a leading genetic cause of infant mortality, shows promise in animal models.
A study lead by Northern Arizona University bioengineer Zach Lerner found that wearing a robotic exoskeleton—a leg brace powered by small motors—could alleviate crouch gait in children with cerebral palsy.
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