Ziva Cooper, research director of the UCLA Cannabis Research Initiative, has been awarded a $3.5 million grant from the National Institutes of Health to conduct a five-year study assessing the pain-relieving effects of cannabis and cannabinoids, the chemicals in the cannabis plant.
Endocytosis, a fundamental process that cells use to take in macromolecules, functions a lot like an airlock on a spaceship – but squishier, says Dr. Gunther Hollopeter, assistant professor of molecular medicine at the Cornell University College of Veterinary Medicine.
Signaling a potential major change in cervical cancer screening options for American women, a new study found that mailed self-sampling kits that test for HPV — the virus that can cause cervical cancer — helped significantly more women get screened for the cancer.
Tulane neuroscience professor Jeffrey Tasker was awarded a $2.1 million grant to study the effects of stress on the brain and how severe stress contributes to mental health disorders.
An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia who relapse
Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new biomarker using a noninvasive imaging method that tracks mitochondrial activity in lung tumors.
University of Utah mechanical engineers are developing the world’s first truly bionic legs, a self-powered prosthetic limb with a computer processor and motorized joints in the ankle and knee that enable an amputee to walk with more power, vigor and better balance.
Rutgers, The State University of New Jersey was selected as one of five new hubs under the National Institutes of Health’s Research Evaluation and Commercialization Hubs (REACH) program to speed up the translation of biomedical discoveries into commercially viable diagnostics, devices, therapeutics, and tools to improve patient care, enhance health, and train the next generation of innovators.
The five-year study, which will involve 40 diabetic women and 40 nondiabetic women, is expected to cost $2.7 million. Researcher hopes it will eventually free diabetic women from osteoporosis, one of many diseases that strike diabetics more forcefully than the general population.
The newly developed system prioritizes patients so that cancer doctors have conversations about their values and goals before it is too late.
In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.
A Cooperative Research Center (CRC) has been established by the National Institutes of Health at three institutions including the Lawrence Livermore National Laboratory (LLNL), the University of California, Irvine (UCI) and the University of California, Davis, with a single goal to enhance and accelerate the development of vaccines for Chlamydia trachomatis genital infections.
A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory (LLNL). The center includes two University of California campuses – Irvine and Davis.
Though identifying data typically are removed from medical image files before they are shared for research, a Mayo Clinic study finds that this may not be enough to protect patient privacy.
A Penn State-led, multi-disciplinary and multi-institutional research team aims to develop an innovative robotic training system to reduce the number of complications associated with CVC placement.
CWRU's W. Henry Boom, MD, and a team of collaborators nationally received the first installment of a seven-year contract, totaling $30 million in its first year from the National Institute of Allergy and Infectious Diseases of the NIH, to establish three immunology research centers to accelerate TB vaccine development.
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.
INCLUDE project aims to address conditions and apply knowledge to larger population
Swapping a single amino acid in a simple bacterial protein changes its structure and function, revealing the effects of complex gene evolution, finds a new study published in the journal eLife. The study—conducted using E. coli bacteria—can help researchers to better understand the evolution of transporter proteins and their role in drug resistance.
Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.
Compared with other world groups, the DNA of Melanesian populations carries some of the largest percentage of ancestry from now-extinct Neanderthals and Denisovans. A genomic study of Melanesians suggests that certain genetic variants inherited from archaic human-like species may have helped these modern people adapt to their tropical island environment.
A biomedical engineering professor at Binghamton University, State University of New York is trying to find a cure for diabetes from several different angles, and three federal grants totaling nearly $1.2 million will aid her and her research team in that quest.
A genetic link has now been found for some instances of Sudden Infant Death Syndrome, or SIDS. The new UW Medicine research study is the first such to make an explainable link.
Organic chemists have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs – including one most commonly used to treat ovarian cancer – are produced. Their discovery, published today in the journal Chem, gives drug makers a crucial building block for creating medicines that, so far, are made with complex processes that result in a lot of waste.
As part of an effort to improve long-term outcomes, a national team led by a researcher at Penn Medicine has launched a study--funded by a $9.8 million grant from the NIH--to better understand clinical and biological processes that occur after transplant and lead to the development of these complications.
Wistar and collaborating institutions have received a major grant from the National Institutes of Health to further research on new melanoma targeted therapies integrating the role of the tumor microenvironment in influencing response to therapy and development of resistance.
Study based at the Icahn School of Medicine at Mount Sinai and other centers finds new system has safety, efficacy benefits for people with type 1 diabetes
This month, the UCLA Jonsson Cancer Center has launched a pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial that will attack cancer cells by simultaneously recognizing two targets – CD19 and CD20 – that are expressed on B-cell lymphoma and leukemia.
The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and the University of California, San Francisco (UCSF), to advance treatments for frontotemporal lobar degeneration (FTLD).
This grant will provide significant research funds for UTEP cancer scientists to understand better the molecular mechanisms, and possible environmental and lifestyle factors that contribute to this multifaceted disease.
Penn Medicine researchers explore a T cell's path to exhaustion and what triggers it.
The effects of a traumatic brain injury (TBI) are pretty clear – problems with memory, headaches, and emotions – but what’s unclear is the underlying pathological causes for those symptoms. According to new research led by researchers at the National Institutes of Neurological Disorders and Stroke (NINDS) in collaboration with the Uniformed Services University (USU), those underlying pathological causes may actually involve more extensive blood vessel damage than previously known. These findings could help target better treatment of these common injuries.
A new study led by UCLA researchers, have found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma, one of the deadliest and most aggressive forms of skin cancer.
The National Institutes of Health (NIH) Director’s New Innovator Award supports highly innovative research proposals and UD's April Kloxin has been honored for her work to tackle idiopathic pulmonary fibrosis.
The award will allow the New Jersey Minority Aging Collaborative (NJMAC), led by the Rutgers Institute for Health, Health Care Policy and Aging Research, to build the infrastructure necessary to enable minority older adults across the state to participate in clinical studies. This will provide researchers and the community with more relevant information and ultimately serve to improve health equity in New Jersey.
In the largest and most diverse genetic study of PTSD to date, scientists from UC San Diego School of Medicine and more than 130 institutions in the Psychiatric Genomics Consortium found that genetics accounts for five to 20 percent of the variability in PTSD risk following a traumatic event.
A team of researchers at the University of Georgia will study how legalized medical cannabis affects people living with chronic pain.
Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson’s and Alzheimer’s disease.
Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.
Penn Medicine has been awarded five grants from the NIH HEAL Initiative, totaling more than $22 million to apply scientific solutions to reverse the national opioid crisis.
University of California, Irvine researcher Kevin Beier, PhD, assistant professor of physiology and biophysics in the School of Medicine, received a 2019 NIH Director’s New Innovator Award to study learning and memory in an effort to discover new treatments for behavioral symptoms of chronic stress and depression. Beier will receive $1.5M in funding over five years.
A new nationwide clinical trial hopes to discover if patients that experience cardiac arrest survive more often and have a better recovery based on how long they have their body temperature cooled.
Xiaochang Zhang, PhD, an assistant professor of human genetics at the University of Chicago, has received a National Institutes of Health (NIH) Director’s New Innovator Award for 2019.
A new test to determine whether antibiotics will be effective against certain bacterial infections is helping physicians make faster and better prescription treatment choices.
UC San Diego researchers investigated how a type of immune cell called a macrophage becomes specialized to the liver. Their study, published October 3, 2019 in Immunity, sets the stage for understanding how macrophage specialization gets disrupted by — or contributes to — liver disease.
The CDC issued new guidance in July on the use of personal protective equipment (masks, gowns) by healthcare providers to protect patients in nursing home facilities from acquiring and spreading antibiotic-resistant germs to others. UMSOM researchers will be testing the new guidelines with $1.1 million CDC grant.
The Congress of Neurological Surgeons Foundation (CNS Foundation) announced a second K12 award will be funded by a generous gift from the Congress of Neurological Surgeons (CNS). The award is made possible through a collaboration with the Foundation of the National Institutes of Health (FNIH) and the National Institutes of Health (NIH).
Notre Dame's Cody Smith has been granted a highly competitive National Institutes of Health Director’s New Innovator Award that will allow him to perform bold research that has the potential to impact a broad area of science.
AACI will present 2019 Public Service Awards to U.S. Representatives Kathy Castor (D-FL) and Fred Upton (R-MI) on Monday, October 21, during the AACI/CCAF Annual Meeting at The Mayflower Hotel in Washington, DC.
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