Intermountain Healthcare Precision Genomics has developed a new gene panel that will provide clinical utility to classify and diagnose certain types of blood cancers.
The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments, reports a new study led by UCL researchers.
Studies found that non-medical use of prescription stimulant medications is a growing problem in the U.S. and that using these medications in ways not prescribed can lead to serious adverse health outcomes, with the risk increasing if they are taken by non-oral routes.
Recap of program featuring biotech startups building platforms in the fight against the opioid crisis.
How do plants space out their roots? A Japanese research team has identified a peptide and its receptor that help lateral roots to grow with the right spacing. The findings were published on December 20, 2018 in the online edition of Developmental Cell.
Media advisory: To contact corresponding study author Scott E. Hadland, M.D., M.P.H., M.S., email Jenny Eriksen at [email protected]. The full study, invited commentary and a summary podcast are linked to this news release and a visual abstract is below.
New research from NYU School of Medicine and Boston Medical Center published online January 18 in JAMA Network Open shows that increased marketing of opioid products to physicians -- from consulting fees to free meals -- is associated with higher opioid prescribing rates and elevated overdose deaths in the U.S.
Loyola Medicine has announced that Daniel P. Isacksen, Jr. has been named regional chief financial officer, a promotion from his post as regional senior vice president of finance and assistant treasurer.
University at Buffalo researchers received an $880,000 grant to help quicken the development of generic equivalents of contraceptives and other drugs delivered vaginally or to the uterus, such as by intrauterine devices (IUD).
Chiropractors from across the nation gathered in Washington, D.C. today to urge members of Congress to increase coverage of non-drug approaches to pain management to help combat the opioid crisis. The Advocacy Day event is part of the American Chiropractic Association’s annual meeting, the 2019 National Chiropractic Leadership Conference (NCLC).
For patients undergoing surgery, having a baby, or needing emergency treatment following a traumatic incident, odds are the hands-on anesthesia care essential to their comfort and safety will be provided by a Certified Registered Nurse Anesthetist (CRNA).
The University of Delaware's Kelvin Lee has received the 2019 Marvin J. Johnson Award in Microbial & Biochemical Technology from the American Chemical Society’s Division of Biochemical Technology.
يعتقد الباحثون وجود ارتباط بين اليقظة والتخفيف من الأعراض التي تعاني منها النساء في سن اليأس، وذلك وفقًا لدراسة أُجريت في Mayo Clinic ونُشرت مؤخرًا في Climacteric: مجلة الجمعية الدولية لسن اليأس. اكتشف الباحثون أن الوعي قد يكون مفيدًا بشكل خاص للنساء اللواتي يعانين من انقطاع الطمث ويعانين من التهيج والقلق والاكتئاب.
Scientists at Washington University School of Medicine in St. Louis have developed a gene therapy that blocks axonal degeneration, preventing axon destruction in mice and suggesting a therapeutic strategy that could help prevent the loss of peripheral nerves in multiple conditions.
The 3D structure of McbBCD, an enzyme (protein) that makes the potent antibiotic microcin B17 from a smaller protein known as a peptide, as revealed by X-ray crystallography. The red spheres show chemical "cycles" formed by the enzyme that are required for antibacterial activity. Image: Dmitry Ghilarov High Res MEDIA CONTACT Todd Bates 848-932-0550 [email protected] YOU MAY ALSO LIKE Scientists Use Bear Saliva to Rapidly Test for Antibiotics Scientists at Rutgers and universities in Russia, Poland and England have solved a nearly 30-year mystery – how the molecular machinery works in an enzyme that makes a potent antibiotic. The findings, which appear in the journal Molecular Cell, provide the tools to design new antibiotics, anticancer drugs and other therapeutics.
The College of American Pathologists (CAP) today published the first-ever evidence-based clinical practice guideline to help laboratories use quantitative image analysis (QIA) in HER2 immunohistochemistry (IHC) testing for breast cancer. The guideline was published in an early online edition of the Archives of Pathology & Laboratory Medicine.
Researchers at Johns Hopkins Medicine say they have added to evidence that rapid resistance gene sequencing technology can accurately speed the identification of specific antibiotic-resistant bacteria strains that sicken and kill some patients. A report on a proof of concept study, published in the January 2019 issue of Antimicrobial Agents and Chemotherapy, suggests the technology has the potential to hasten the “personalized” choice of antibiotics critically ill patients need.
A new collection of reviews and original research illustrate how new technologies and advanced cell culture are accelerating basic research, drug discovery and drug development.
1 in 10 children and about 1 in 6 adults with private insurance received antibiotics they didn’t need at least once in 2016, a new Michigan Medicine study suggests.
Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children’s Hospital of Philadelphia. The patients used less than 25 percent of the drugs, suggesting a potential risk of opioid diversion.
The High Flux Isotope Reactor and the Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory have reached new levels of increased science productivity. In 2018, a record high of more than 500 scientific instrument publications were produced between HFIR and SNS—based on neutron beamline experiments conducted by more than 1,200 US and international researchers who used the world-leading facilities.
The use of antibiotics to treat inflammatory skin conditions like acne and rosacea is decreasing over time, but there has been an increase in prescriptions associated with dermatologic surgical procedures.
A practical resource-based public health approach for the rapid initiation of antiretroviral therapy in HIV-infected individuals living in low- and middle-income countries could save thousands of lives, according to an Essay published January 15 in the open-access journal PLOS Medicine by Mark Tenforde of the University of Washington School of Medicine, and colleagues.
While more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that more 95 percent actually can be treated safely with this class of antibiotics, improving treatment outcomes and reducing the risk of infection with dangerous resistant pathogens such as Clostridium difficile (C. difficile). A review article in the January 15 issue of JAMA recommends best practices for evaluation of reported penicillin allergies and provides clinicians with guidance and tools to help determine appropriate procedures based on the severity of previously reported reactions.
Hospital for Special Surgery and other centers are enrolling patients in a clinical trial to determine if krill oil supplements could improve quality of life for people with lupus.
The University of Texas MD Anderson Cancer Center and Dragonfly Therapeutics, Inc., today announced a strategic collaboration to bring Dragonfly’s TriNKET™ (tri-specific natural killer cell engager therapy) immunotherapy drug candidates to patients in clinical trials beginning in 2019.
Researchers found that personality traits have a significant bearing on a person’s attitudes toward obesity, their implicit theories of weight and their willingness to engage in derisive fat talk or weight discrimination.
There is little benefit for those over 70 taking higher dose vitamin D supplements to improve their bone strength and reduce the risk of falls, new research has revealed.
English patients living in poorer areas are likely to be prescribed more opioids by their GPs, according to a study led by the University of Manchester and University of Nottingham researchers. The research also shows how smoking, obesity and depression are all associated with more prescribing of the drugs for problems such as lower back pain and arthritis.
A new long-acting contraceptive designed to be self-administered by women may provide a new family planning option, particularly in developing nations where access to healthcare can be limited, a recent study suggests. The contraceptive would be delivered using microneedle skin patch technology originally developed for the painless administration of vaccines.
For the first time, researchers at University of California San Diego have used rapid 3D printing technologies to create a spinal cord, then successfully implanted that scaffolding, loaded with neural stem cells, into sites of severe spinal cord injury in rats.
In a pioneering clinical trial that will attack Alzheimer’s disease by targeting inflammation in the brain’s blood vessels, researchers at the George & Anne Ryan Institute for Neuroscience have received regulatory approval to initiate the BEACON Study.
The radioisotope technetium-99m is used in 80 percent of all nuclear medicine imaging procedures worldwide. However, it is often in short supply. Nuclear engineers at Oregon State University are working to produce a comparable radioisotope, molybdenum-99, that can be used instead.
A University of Wisconsin–Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.
In a trial of one of the main class of prescription sleeping pills, half the participants slept through a fire alarm as loud as someone vacuuming next to their bed. But a newer alternative preserves the ability to wake in response to danger signals, according to a new research.
Incorporating pharmacists with an expanded scope into the community or hospital emergency departments (ED) could significantly reduce ED crowdedness, according to a new study.
In studying a bacterium that causes disease in hospitalized people, researchers at Washington University School of Medicine in St. Louis have figured out a key step in the transmission of antibiotic resistance from one bacterium to another. Their insight suggests a new strategy for stopping the spread of antibiotic resistance.
More than half of people who take medical cannabis for chronic pain say they’ve driven under the influence of cannabis within two hours of using it, at least once in the last six months, according to a new survey. One in five of them said they’d driven while ‘very high’ in the past six months.
A special edition of National Geographic on "The Future of Medicine" highlights the innovative stem-cell science of Cedars-Sinai, showing how investigators are seeking to use stem cells and Organ-Chips to tailor personalized treatments for individual patients. Downloadable video available.
The study suggests better measures for accurate dosages of blood thinners in obese patients
A University of South Australia scientist has called for Australia to embrace pharmacogenetic (PGx) testing to deliver medication more effectively and slash around $2.4 billion wasted each year through unsafe and ineffective drug prescriptions.
The American Society of Anesthesiologists (ASA) will host PRACTICE MANAGEMENT™ 2019, Jan. 18-20, in Las Vegas. The three-day meeting will bring together leaders and subject-matter experts in anesthesia to share new research, knowledge and critical skills needed to optimize an anesthesiology practice’s performance.
John “Chip” Tilton, MD, of Case Western Reserve University School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton’s project will address a major challenge in developing nanoscale therapeutics: finding ways to deliver them to the right location inside the body.
Los investigadores de Mayo Clinic junto con otros colaboradores de la Escuela de Medicina de la Universidad de Wake Forest y del Centro de Ciencias de la Salud de la Universidad de Texas en San Antonio publicaron los resultados de un ensayo clínico sobre la seguridad y la factibilidad de extraer células senescentes en un pequeño grupo de pacientes con fibrosis pulmonar.
Wistar, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc. announce the FDA has approved the initiation of a first-in-human clinical trial investigating safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody (DMAb) therapeutic technology for the prevention of Zika virus infection.
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