Feature Channels: All Journal News

• share
• favorite_border

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.

• share
• favorite_border

A novel insect-inspired flying robot, developed by TU Delft researchers from the Micro Air Vehicle Laboratory (MAVLab), has been presented in Science (14 September 2018). Experiments with this first autonomous, free-flying and agile flapping-wing robot improved our understanding of how fruit flies control aggressive escape manoeuvres.

• share
• favorite_border

When it comes to breast cancer subtype in the Garden State, researchers from Rutgers University and the New Jersey State Cancer Registry find that non-Hispanic black women and women between the ages of 20 to 39 have higher rates of triple-negative disease than females aged 50 to 64 and those of other races and ethnicities.

• share
• favorite_border

Researchers generated stable lines of spinal cord neural stem cells in culture. Transplanted into a rat model of spinal cord injury, the cells enabled robust regeneration of functional neurons along the length of the spine.

• share
• favorite_border

Some kindergartners and first-graders suspended from school can find it challenging to reverse the negative trajectory in their academic life, says a University of Michigan researcher.

• share
• favorite_border

Astrocytes' important role in brain function suggests they are also involved in disease. Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified an astrocyte subpopulation as the dominant cell type to spring into action in vivo (in a living organism) in a neuroinflammatory disease setting. The study published today in eNeuro.

• share
• favorite_border

New study indicates common satellite imaging technologies vastly underestimate number of fires in Florida, detecting only 25 percent of burn area.

• share
• favorite_border

Researchers examined the costs associated with screening for prostate cancer, including treatment, for three years after diagnosis. They estimated that for men diagnosed in each of 2004, 2005, 2006, and 2007, the total cost for treating and screening for each group would be $1.2 billion for three years after diagnosis.

• share
• favorite_border

The research will not only aid basic understanding of brain development, but also provide a foundation for understanding the cellular origins of brain disorders caused by errors in development. These anatomical defects include Joubert syndrome, Dandy-Walker malformation and pontocerebellar hypoplasia. The database will enable future studies tracing the cellular origins of childhood brain tumors such as medulloblastoma, astrocytoma and ependymoma. Researchers worldwide can interact with the data via an interface St. Jude has created called Cell Seek.

• share
• favorite_border

Argonne scientists have developed a neural network that can identify the structure of molecules in the gas phase, offering a novel technique for national security and pharmaceutical applications.

• share
• favorite_border

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.

• share
• favorite_border

Vanderbilt-Ingram Cancer Center researchers have answered questions about the incidence and timing of rare but sometimes fatal reactions to the most widely prescribed class of immunotherapies.

• share
• favorite_border

Printed electronics use standard printing techniques to manufacture electronic devices on different substrates like glass, plastic films, and paper. Interest in this area is growing because of the potential to create cheaper circuits more efficiently than conventional methods. A new study published in AIP Advances provides insights into the processing of copper nanoparticle ink with green laser light.

• share
• favorite_border

In an unusual observation, astronomers used the National Science Foundation's Very Long Baseline Array (VLBA) to study the effects on radio waves coming from a distant radio galaxy when an asteroid in our Solar System passed in front of the galaxy. The observation allowed them to measure the size of the asteroid, gain new information about its shape, and greatly improve the accuracy with which its orbital path can be calculated.

• share
• favorite_border

Researchers at the University of New Hampshire will undertake the largest study ever conducted on intimate partner violence among lesbian, gay, bisexual and other sexual minority college students thanks to a grant from the National Science Foundation.

• share
• favorite_border

As if college were not difficult enough, more than one-third of first-year university students in eight industrialized countries around the globe report symptoms consistent with a diagnosable mental health disorder, according to research published by the American Psychological Association.

• share
• favorite_border

For thousands of years, humans have relied on storytelling to engage, to share emotions and to relate personal experiences. Now, psychologists at McMaster University are exploring the mechanisms deep within the brain to better understand just what happens when we communicate.

• share
• favorite_border

Placing trust in doctors to advocate for their health needs, older adults rarely ask for referrals to specialists, specific prescriptions, express concerns or follow-up after medical visits.

• share
• favorite_border

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology.

• share
• favorite_border

Medicaid expansion under the Affordable Care Act does not appear to reduce disparities in use of regionalized surgical care among vulnerable persons.

• share
• favorite_border

If you’re looking into the mouth of a brown bear, one of the world’s top predators, your chances of survival probably aren’t good. But a team of Rutgers and other scientists has discovered a technology that rapidly assesses potentially lifesaving antibiotics by using bacteria in saliva from an East Siberian brown bear. The technology involves placing a bacterium from a wild animal’s mouth – or other complex source of microbes with potential antibiotic properties – in an oil droplet to see if it inhibits harmful bacteria, such as Staphylococcus aureus, according to a study published online by the Proceedings of the National Academy of Sciences.

• share
• favorite_border

A team of researchers led by Assistant Professor Yan Ning from the National University of Singapore has developed a new sustainable chemical approach to produce a series of amino acids from woody biomass derivatives such as grass, straw and wood chips from agricultural wastes. The team’s novel chemical method has potential to revolutionise amino acid production of the future and transform the food, pharmaceutical and chemical industries.

• share
• favorite_border

Nearly 2.3 million times last year, Americans learned they had a sexually transmitted disease. But despite these record-high infection rates for chlamydia and gonorrhea, most patients only receive treatment for their own infection – when they probably could get antibiotics or a prescription for their partner at the same time. A team of physicians examines the barriers that stand in the way of getting expedited partner therapy to more people.

• share
• favorite_border

A team led by Marc Ernstoff, MD, of Roswell Park Comprehensive Cancer Center found that a drug complex containing IL-15 is both safe and well tolerated in patients with advanced solid tumors.

• share
• favorite_border

Getting magnetic resonance imaging (MRI) scans twice a year instead of one annual mammogram is far more effective at detecting early breast cancers in young women with a high-risk genetic profile than mammograms alone, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.

• share
• favorite_border

To protect the public from harmful products, legal action can be used against industries, one example of which—a settlement with the tobacco industry—offers useful lessons for confronting several of today’s public health epidemics.

• share
• favorite_border

A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at Washington University School of Medicine in St. Louis. Such a practice could help doctors identify patients at high risk of disease recurrence early after a transplant and help guide treatment decisions.

• share
• favorite_border

Two new studies by scientists at Scripps Research are bringing Ebola virus’s weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection—not only for Ebola virus, but for other closely related pathogens as well.

• share
• favorite_border

Swapping electrons for photons, researchers in the School of Engineering & Applied Science have developed wireless sensors which are not subject to electromagnetic interference and are smaller and generally more flexible than the currently electronics-based technology.

• share
• favorite_border

Physicists at Indiana University have been awarded $2 million from the National Science Foundation to lead an experiment on neutrons that could resolve a fundamental mystery about the universe.

• share
• favorite_border

A major US children's hospital introduced a first-of-its-kind project to eliminate or reduce pain from elective needle procedures in all infants and children, reports a study in PAIN Reports®, part of a special issue on research innovations in pediatric pain. The official open-access journal of the International Association for the Study of Pain (IASP), PAIN Reports is published in the Lippincott portfolio by Wolters Kluwer.

• share
• favorite_border

While news media reporting traffic crashes and fire-related deaths of infants and children is routine and often leads to preventative measures to reduce these deaths, there is little or no news coverage of sleep-related or sudden infants deaths, which contributes to the lack of efforts to prevent these deaths, according to a Rush physician.

• share
• favorite_border

It’s known as the disease that attacks the body but leaves the mind unaffected. But a new study shows that amyotrophic lateral sclerosis, also called ALS or Lou Gehrig’s disease, does affect the mind, especially later in the disease. The study is published in the September 12, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• share
• favorite_border

A new wearable ultrasound patch that non-invasively monitors blood pressure in arteries deep beneath the skin could help people detect cardiovascular problems earlier on and with greater precision. In tests, the patch performed as well as some clinical methods to measure blood pressure. Applications include real-time, continuous monitoring of blood pressure changes in patients with heart or lung disease, as well as patients who are critically ill or undergoing surgery.

• share
• favorite_border

Among older Americans, the poorest are the most likely to have used prescription opioids, according to a University at Buffalo study providing new insights into unexplored contours of the opioid crisis. The study also raises important questions about access to pain management options for the disadvantaged in the current climate of the opioid epidemic.

• share
• favorite_border

New method can make films of atomically thin carbon that are over a foot long.

• share
• favorite_border

About 61 percent of the world’s 356 turtle species are threatened or already extinct, and the decline could have ecological consequences.

• share
• favorite_border

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have found that the anti-malaria drug amodiaquine inhibits the apelin receptor protein, which helps drive the vascularization behind diabetic retinopathy, wet age-related macular degeneration (AMD) and other conditions. Because the drug has been approved to treat malaria for decades, it could move relatively quickly through the pipeline to help patients. The study was published in the journal PLOS ONE.

• share
• favorite_border

Humans arrived on the tropical island of Madagascar more than 6,000 years earlier than previously thought based on an analysis of bones from what was once the world’s largest bird, according to a study led by Stony Brook University researcher Dr. Pat Wright and published today in the journal Science Advances.

• share
• favorite_border

St. Jude Children’s Research Hospital investigators have unraveled the origins and identified mutations associated with a perplexing form of acute leukemia. The landmark study appears today as an advance online publication in the journal Nature and lays the foundation for more effective treatment of patients with the high-risk cancer. The research focused on mixed phenotype acute leukemia (MPAL), a subtype of acute leukemia that accounts for about 3 percent of the estimated 3,500 pediatric cases of acute leukemia diagnosed annually in the U.S. Their treatment is complicated because MPAL does not fit cleanly into a single diagnosis, but includes features of both acute lymphoblastic leukemia and acute myeloid leukemia.

• share
• favorite_border

Using new bioinformatics tools to analyze thousands of human tissue samples, researchers created a new database of daily rhythms in human gene activity—including many genes that regulate how drugs work. Reporting in Science Translational Medicine, scientists say their results could have significant implications for a growing field of study called circadian medicine.

• share
• favorite_border

Omacetaxine (to block protein synthesis) with venetoclax (to block oxidative phosphorylation), was highly effective against CD123+ leukemia stem cells.

• share
• favorite_border

While conventional wisdom says that people don’t like uncertain gains or rewards, a study from the University of Chicago Booth School of Business finds that uncertainty can play an important role in motivating repeat behaviors.

• share
• favorite_border

Researchers from St. Jude Children’s Research Hospital and the University of North Carolina Lineberger Comprehensive Cancer Center have made important discoveries that could lead to better treatment for a rare blood cancer in children that has features of both acute myeloid leukemia and acute lymphoblastic leukemia.

• share
• favorite_border

A team of scientists has uncovered the neural processes mice use to ignore their own footsteps, a discovery that offers new insights into how we learn to speak and play music.

• share
• favorite_border

Research from Michigan State University shows that keeping up with email traffic places high demands on managers, which prevents them from achieving their goals and from being good leaders.

• share
• favorite_border

New York University physicists have created new techniques that deploy machine learning as a means to significantly improve data analysis for the Large Hadron Collider, the world’s most powerful particle accelerator.

• share
• favorite_border

Prof. Yardena Samuels of the Weizmann Institute, working with a global team, has developed a way to target a patient's unique melanoma cells. The immunotherapy creates, in effect, a new drug for each person.

• share
• favorite_border

The majority of partnered, home-dwelling people in the U.S. with dementia are sexually active, according to a University of Chicago Medicine study out this week in the Journal of the American Geriatrics Society.

• share
• favorite_border

In a proof of concept study, scientists at Johns Hopkins report they have successfully performed 3D personalized virtual simulations of the heart to accurately identify where cardiac specialists should electrically destroy cardiac tissue to stop potentially fatal irregular and rapid heartbeats in patients with scarring in the heart. The retrospective analysis of 21 patients and prospective study of five patients with ventricular tachycardia, the researchers say, demonstrate that 3D simulation-guided procedures are worthy of expanded clinical trials.