Curated News: Grant Funded News

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The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND). This research project aims to evaluate whether delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) alone or in combination can potentially alter DNA methylation, which is a biological process that can create a change in the expression of certain genes.

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A group of international collaborators led by researchers from the University of Pittsburgh identified new genetic associations that can predict individual susceptibility to Takayasu arteritis.

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A new computational method from the McKelvey School of Engineering helps scientists validate the accuracy of microscopic images

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University of South Australia thermal energy researcher Professor Frank Bruno has been awarded almost $1 million by the Federal Government to find a solution to agricultural pollution in Australia and India.

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The nation’s largest colorectal cancer advocacy organization keeps fighting to lower the screening age and increase access in Kentucky, Nebraska, Rhode Island, and Texas.

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Researchers recently created detailed simulations showing how stiff red blood cells flow through blood vessels, deforming and colliding along the way.

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Despite many occurrences of red tide and blue green algae in Florida waters, the understanding of the health effects of exposure to these blooms is limited. Researchers will evaluate short- and long-term health effects of exposure to harmful algal blooms (HABS) in Florida to capture key areas of human exposure and a wide demographic population profile. They also will evaluate the potential effect of exposure to COVID-19 on susceptibility to HABs and health outcomes in this study population.

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Dr. Jennifer Kraschnewski, professor of medicine, public health sciences and pediatrics at Penn State College of Medicine, has received $2.69 million through the Patient-Centered Outcomes Research Institute (PCORI) to establish projects aimed at addressing COVID-19 health disparities among nursing home residents and racial and ethnic minorities.

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A study from researchers at Washington University School of Medicine in St. Louis has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue to why the bacteria have been linked to nutritional problems such as malnutrition and stunted growth.

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An enzyme in the colon lining releases hydrogen peroxide – a known disinfecting compound- to protect the body from gut microbial communities. Findings from the UC Davis Health study points to importance of considering a different approach to treating gut inflammation and bacterial imbalance in the colon.

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Hackensack Meridian – Meridian Health Foundation received a grant for $25,000 from the TD Charitable Foundation to support the Reducing Barriers to Mammograms at the Shore program, which provides free mammograms, diagnostic screenings and procedures to women in Monmouth and Ocean County who are low-income, have no available financial resources, are experiencing financial hardship, or are uninsured or underinsured.

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What happens when different strains of bacteria are present in the same system? Do they co-exist? Do the strongest survive? In a microbial game of rock-paper-scissors, researchers at the University of California San Diego’s BioCircuits Institute uncovered a surprising answer.

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New study in mice finds that a high-fat diet allows cancer cells to outcompete immune cells for fuel, impairing immune function and accelerating tumor growth. Findings suggest new strategies to target cancer metabolism, improve immunotherapies.

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Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes. The study, which will be published December 9 in the Journal of Experimental Medicine (JEM), reveals that inhibiting a protein called OCA-B protects mice from type 1 diabetes by limiting the activity of immune cells that would otherwise destroy the pancreas’ insulin-producing β cells.

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Engineers have created 3D printed patient-specific models of the aorta that can aid presurgical planning and improve outcomes of minimally invasive valve replacement.

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The University of Chicago Medicine has received an $8 million donation from AbbVie, as part of the research-based global biopharmaceutical company’s broader $50 million, five-year investment in philanthropic partners to support underserved Black communities across the United States.

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The San Diego Supercomputer Center (SDSC) at UC San Diego announced that its new Expanse supercomputer formally entered service for researchers following a program review by the National Science Foundation (NSF), which awarded SDSC a grant in mid-2019 to build the innovative system.

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Two Cornell University researchers are looking into a new way to meet the growing demand for wireless services in the U.S.

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A professor at the University of Arkansas at Little Rock has received a $133,333 grant from the National Endowment for Humanities to publish the most complete edition of 18th-century French philosopher Louise Dupin’s unpublished treatise “Work on Women.” 

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The MIPT Center for Photonics and 2D Materials has been named among the winners of the eighth competition for megagrants from the Russian government. The funding will go toward research on advanced nanophotonics: quantum materials and artificial intelligence.

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DALLAS – Dec. 8, 2020 – Two studies led by UT Southwestern researchers shed new light on how the brain encodes time and place into memories. The findings, published recently in PNAS and Science, not only add to the body of fundamental research on memory, but could eventually provide the basis for new treatments to combat memory loss from conditions such as traumatic brain injury or Alzheimer’s disease.

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Researchers at Rutgers Robert Wood Johnson Medical School have reported the first instance of COVID-19 triggering a recurrence of Guillain–Barré Syndrome – a rare disorder where the body’s immune system attacks nerves and can lead to respiratory failure and death.

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As the U.S. Army modernizes weapons systems and combat vehicles, researchers at Missouri S&T are developing lightweight and ultra-high-strength steels for next-generation combat vehicles that improve blast resistance and lower transportation costs.“Missouri S&T offers one of only seven metallurgical engineering programs in the U.

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The COVID-19 Testing Impact Calculator is a free resource that shows how different approaches to testing and other mitigation measures, such as mask use, can curb the spread of the virus in any organization.

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A multi-disciplinary, multi-institutional group has identified a solution to two of most pressing issues in a key fuel cell component — the catalyst used to drive the reactions.

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Henry Ford Health System today announced a $16 million gift to its Henry Ford Pancreatic Cancer Center (HFPCC), which was launched in 2018 by an initial $20 million gift from the same donor, who wishes to remain anonymous. The gift will bolster the HFPCC’s clinical and translational research endeavors in the fight against this devastating disease, for which the five-year survival rate is only 9 percent.

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UIC’s Energy Resources Center, UIC-ERC, will receive $1.8 million over a 3 year period, beginning in 2021.

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Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine learning algorithm to create human liver organoids with blood and bile handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

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Researchers at Washington University School of Medicine in St. Louis have found a novel form of the Alzheimer’s protein tau in the fluid surrounding the brain and spinal cord. This form of tau — known as MTBR tau — indicates what stage of Alzheimer’s a person is in and tracks with tangles of tau protein in the brain.

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Researchers at La Jolla Institute for Immunology (LJI) have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.

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In a new paper in the journal Nature, BIDMC researchers shed light on the role of antibodies and immune cells in protection against SARS-CoV-2, the virus that causes COVID-19, in rhesus macaques.

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A new study by the UC Davis MIND Institute finds a connection between gestational age and ADHD in children with Down syndrome. An earlier gestational age is linked to higher ADHD symptoms later in childhood.

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A team of Cornell University scientists will use acoustic technology to develop efficient and affordable ways to manage soil-dwelling pests and their predators, thanks to a two-year grant from the USDA.

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DALLAS – Dec. 3, 2020 – A team led by UT Southwestern has derived a new “intermediate” embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.

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Researchers inactivated the gene for CHD7 — whose mutation causes congenital birth defects — in mouse embryos, and then rigorously probed how this change in developing cardiac neural crest cells caused severe defects in the outflow tract and great arteries, leading to perinatal lethality.

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A team of physicists and biologists investigate the effect that the geometry of the biological environment has on cellular movement. Their findings are published in the journal Science.

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The Rutgers Institute for Health, Health Care Policy and Aging Research has received $10 million in funding from the Robert Wood Johnson Foundation and Rutgers University to support the New Jersey Population Health Cohort study – the largest study to date to explore factors that influence health and well-being in New Jersey.

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An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher is identifying the unique biology that may make Black women more susceptible to aggressive breast cancer.

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University of Pittsburgh researchers reveal a molecular basis for the deep and fundamental connection between the disruption in circadian rhythms and predisposition to substance abuse.

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Researchers at Harvard Medical School have successfully reversed age-related vision loss in animals as well as eye damage stemming from with a condition mimicking human glaucoma, a leading cause of blindness around the world.

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Proof-of-concept study represents first successful attempt to reverse the aging clock in animals through epigenetic reprogramming.

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Anita Kinney, professor at the Rutgers School of Public Health and associate director for Population Science and Community Outreach at Rutgers Cancer Institute of New Jersey, is one of ten recipients across the nation of an American Cancer Society and Pfizer community grant of $399,892 to support investigation into reducing racial health disparities in cancer care through precision oncology and immunotherapy.

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A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn’s disease, may disrupt calcium regulation.

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Nanoengineers at the University of California San Diego have developed new and improved probes, known as positive controls, that could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe. The advance could help expand testing to low-resource, underserved areas.

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FAU researchers have received a two-year, $675,000 grant from the National Institute of Aging to test a mathematical model designed to optimize social and physical engagement in this population. The objective of the study is to identify strategies that will facilitate and enhance social interactions with and among older adults and counter age-related decline by pinpointing activities that will allow the social life of older adults to flourish.

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University of California San Diego has been selected by the NIH to lead and administer an international seven-year, $28-million grant for HIV/AIDS clinical trials.

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The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, has been re-funded for the next seven years by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and collaborating NIH Institutes.

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When medically complex children are hospitalized, linking hospitalists to their regular outpatient providers through an inpatient consultation service were more likely to improve outcomes, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

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A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve Board of Governors found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis.

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The uniquely human ability to read is the cornerstone of modern civilization, yet very little is understood about the effortless ability to derive meaning from written words. Scientists at UTHealth have now identified a crucial region in the temporal lobe, know as the mid-fusiform cortex, which appears to act as the brain’s visual dictionary.