Young adults who combine alcohol and cannabis use experience fewer negative consequences when they stick with a single type of drink versus consuming multiple types of alcohol, according to a new study. In addition, by avoiding cannabis concentrate they may steady or lower their overall consumption. The findings suggest that for those who choose to sustain their levels of alcohol and cannabis use, judicious choice of products may reduce the risks.
Giving nurse practitioners the authority to prescribe buprenorphine has brought that gold standard treatment for opioid addiction to people who might not have had access to it before, according to a new study led by Tracy Klein, PhD, associate professor at the Washington State University College of Nursing in Vancouver.
UCLA has received seven grants totaling $6.4 million from the California Bureau of Cannabis Control. The awards will fund studies on topics ranging from the toxicity of inhaled and second-hand cannabis smoke to employment conditions in California’s cannabis industry.
Before the COVID-19 pandemic, information about the dangers of vaping was emerging. To investigate the potentially serious health and respiratory implications of vaping, Mayo Clinic researchers wanted to better understand the factors influencing vaping in the community.
A Rutgers expert discusses the many impacts of COVID-19 on people with substance use disorder and what treatment providers, policymakers and researchers are doing to help.
Both fatal and nonfatal overdoses have increased this year compared to last, according to a recent report by the Overdose Data Mapping Application Program. And, anecdotal information suggests that compared to last year, people in recovery are relapsing at alarming rates.
A wave of new studies shows what happens when surgical teams work together to reduce the emphasis on, and supply of, opioid painkillers while still seeking to ease surgery patients’ pain.
Medical diagnoses involving alcohol-related disorders, substance-related disorders and suicidal thoughts and behaviors – commonly referred to as diseases of despair – increased in Pennsylvania health insurance claims between the years 2007 and 2018, according to researchers.
Study Highlights
• The full impact of COVID-19 on alcohol use is not yet known, but rates have been rising during the first few months of the pandemic
• There’s an urgent need for public health and medical responses to address harmful alcohol use
An epidemic that was already raging before COVID-19 arrived has flared up in recent months, according to a real-time tracking system in Michigan. It shows a 15 percent rise in suspected opioid overdose deaths since March, compared with the same time last year, and a 29% rise in first responders’ use of the rescue drug naloxone.
A new study suggests that patients with opioid use disorder may be identified using information available in electronic health records, even when diagnostic codes do not reflect this diagnosis. The study demonstrates the utility of proxies coding for DSM-5 criteria from medical records to generate a quantitative DSM-5 score that is associated with opioid use disorder severity. The study methods are unique in deriving a severity score that aims to mirror severity scores from more traditional interview-based diagnostic procedures.
Nearly one-third of students who reported misusing prescription opioids as high school seniors between 1997 and 2000, but did not have a history of medical use, later used heroin by age 35, according to a University of Michigan study.
Scientists at Wake Forest School of Medicine have recorded real time changes in dopamine and serotonin levels in the human brain that are involved with perception and decision-making. These same neurochemicals also are critical to movement disorders and psychiatric conditions, including substance abuse and depression.
US veterans with unhealthy alcohol use who reduce their drinking may gain some improvement in chronic pain symptoms and use of other substances, according to a study in Alcoholism: Clinical and Experimental Research. Hazardous drinking is common in the US, and frequently co-occurs with chronic pain, depression and anxiety, and with tobacco, cannabis or cocaine use. Many people use alcohol and other substances to mask or self-manage pain and psychiatric symptoms, although there is little evidence to support such use. If, conversely, a reduction in drinking (or use of treatment for alcohol misuse) were to benefit co-occurring conditions or substance use, this could support an integrated approach to screening or treatment. The new analysis assessed the impact of drinking reduction on improvement of chronic pain, psychiatric symptoms, and other substance use among US veterans with unhealthy alcohol use – a population with high rates of these co-occurring conditions.
The NIH has awarded NYU College of Dentistry researchers Nigel Bunnett, PhD, and Brian Schmidt, DDS, MD, PhD, a $3.9 million grant to study targeting endosomal receptors for the treatment of chronic pain. The five-year grant will support Bunnett and Schmidt’s collaborative research, which aims to ultimately yield improved pain management without the need for opioids.
College students with physical and cognitive disabilities use illicit drugs more, and have a higher prevalence of drug use disorder, than their non-disabled peers, according to a Rutgers study.
Opioid use disorder and overdose have reached unprecedented levels around the world. In the United States, remediation of pain is one of the most common reasons American adults seek healthcare. Therefore, it is vital that clinicians practicing in diverse roles and settings have a clinical understanding of pain and substance use disorders as well as knowledge about public health and opioid policy interventions.
The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the opioid epidemic, a University of Pittsburgh Graduate School of Public Health analysis revealed today.
The University of Texas at El Paso’s Minority AIDS Research Center (MARC) is the subrecipient of a $1 million implementation grant to target substance use disorders and opioid use disorders in five rural counties along the Texas-Mexico border.
The United States has seen a 200% increase in the rate of deaths by opioid overdose in the last 20 years. But many of these deaths were preventable. Naloxone, also called Narcan, is a prescription drug that reverses opioid overdoses, and in more than 40 states — including Pennsylvania — there is a standing order policy, which makes it available to anyone, without an individual prescription from a healthcare provider.
Luis M. Tuesta, Ph.D., assistant professor in the Department of Psychiatry and Behavioral Sciences at the University of Miami Miller School of Medicine, has been awarded the Avenir Award from the National Institute on Drug Abuse, part of the National Institutes of Health, to study the epigenetic mechanisms of microglial activation and their role in shaping the behavioral course of opioid use disorder.
Cigarette smoking is associated with frequent substance use and poor behavioral and physical health in sexual and gender minority populations, according to Rutgers researchers.
To better understand the effect of the COVID-19 pandemic on cannabis and CBD use, the UCLA Cannabis Research Initiative has launched the Cannabis, CBD and COVID Survey.
As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor. Now UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA receptor. The findings were published online today in the journal Nature.
People have traded in nightclubs and dance festivals for virtual raves and Zoom happy hours as a result of lockdowns during the COVID-19 pandemic—yet, many are using drugs in these socially distanced settings, according to a new study by researchers at NYU Grossman School of Medicine and the Center for Drug Use and HIV/HCV Research at NYU School of Global Public Health.
FACULTY Q&ABoth fatal and nonfatal overdoses have increased this year compared to last, according to a recent report by the Overdose Data Mapping Application Program. And, anecdotal information suggests that compared to last year, people in recovery are relapsing at alarming rates.Faculty from the University of Michigan School of Nursing’s Center for the Study of Drugs, Alcohol, Smoking and Health discuss why the pandemic has hit people with substance abuse problems especially hard and the expanded role of virtual recovery programs.
Mizuho OSI®, a leading manufacturer of specialty surgical tables and pressure injury abatement solutions would like to announce the publication of a new clinical study titled “23-hour Total Hip Replacement Requiring Only 3.5 Opioid Pills Through 6 Weeks: A Non-selected Prospective Consecutive One Year Cohort”, by Andrew Wickline MD, now appearing in the peer-reviewed Journal of Orthopedic Experience & Innovation (JournalOEI)
A recent study from IUPUI found risk factors for substance use disorder affect age groups differently and proposes a primary prevention strategy for substance use disorder that is individualized for people within defined age groups.
Watch live and recorded press conferences at https://www.acs.org/content/acs/en/pressroom/news-room/press-conferences.html. Press conferences will be held Monday, Aug. 17 through Thursday, Aug. 20, 2020
Both fatal and nonfatal overdoses have increased this year compared to last, according to a recent report by the Overdose Data Mapping Application Program. And, anecdotal information suggests that compared to last year, people in recovery are relapsing at alarming rates.
Faculty from the University of Michigan School of Nursing's Center for the Study of Drugs, Alcohol, Smoking and Health discuss why the pandemic has hit people with substance abuse problems especially hard and the expanded role of virtual recovery programs.
Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.
University of Wisconsin–Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies. These antibodies may contribute to some of the negative side effects of long-term opioid use.
The “secret shopper” study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.
Affiliates with Notre Dame’s Wilson Sheehan Lab for Economic Opportunities found that greater exposure to the opioid crisis increases the chance that a child’s mother or father is absent from the household and increases the likelihood that he or she lives in a household headed by a grandparent.
Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought.
Penn Medicine researchers found that when an “Enhanced Recovery After Surgery” protocol was employed—which optimizes patients’ surgical care before, during, and after surgery—the majority of patients did not need opioids for pain management at one, three, and six months after elective spinal and peripheral nerve surgery.
Sanford Burnham Prebys Medical Discovery Institute has been awarded a $4.5 million grant from the National Institutes of Health (NIH) to identify new therapies for mental health disorders. The research will be headed by Layton Smith, Ph.D., and Michael Jackson, Ph.D., of the Institute’s Conrad Prebys Center for Chemical Genomics. The funding supports the discovery of new classes of drugs that target “orphan” receptors to treat psychological conditions such as schizophrenia, depression, anxiety and substance abuse.
Drug overdoses are psychologically traumatic events that can lead to symptoms of post-traumatic stress disorder (PTSD), according to a study focused on female sex workers in Baltimore City led by researchers at the Johns Hopkins Bloomberg School of Public Health.
A longitudinal study of more than 230 teens and young adults in Washington state finds that teens may be more likely to use marijuana following legalization – with the proliferation of stores and increasing adult use of the drug -- than they otherwise would have been.
Tufts awards seed funding to 8 projects that seek to address the complex individual & community challenges wrought by the opioid epidemic. The inaugural awards of the Tufts Initiative on Substance Use and Addiction demonstrate a multidisciplinary drive to address this pressing public health crisis.
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