Feature Channels: Women's Health

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Many people would be surprised to learn that among developed countries, the United States not only has the highest rate of maternal mortality (death during pregnancy or within one year of birth), but that it increased 56% between 1990 and 2015. Older age and conditions such as diabetes, high blood pressure and obesity increase the risk, which is why the American Society of Anesthesiologists (ASA) says expectant mothers should talk with their obstetrician and physician anesthesiologist to develop a plan that ensures the safest pregnancy, childbirth and recovery.

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New research from FSU has found that Seeking Safety, a cognitive behavior-based intervention program, is a promising program for reducing incarcerated women’s symptoms of depression and post-traumatic stress disorder. FSU College of Social Work Associate Professor and Associate Director of the Institute for Justice Research and Development Stephen J. Tripodi.

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The discovery highlights alternative treatment options to pharmaceutical medications.

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Much like cancer, sepsis isn’t simply one condition, but rather many conditions with varying clinical characteristics that could benefit from different treatments, according to a study involving more than 100,000 patients. The findings could explain why several recent clinical trials have failed.

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In a study published today in the Nature Communications, researchers from King's College London have shown how skin vaccination can generate protective CD8 T-cells

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Last year, an estimated 18 million cancer cases existed worldwide. This year, an estimated 1.76 new cancer cases will be diagnosed and 606,000 cancer deaths will occur in the United States. The number of cancer survivors worldwide is also growing, with more than 15.5 million cancer survivors in the United States alone – a figure expected to double in the coming decades. Ongoing research is necessary to help prevent and treat cancer. This is a selection of related research that will be presented during ACSM's 66th Annual Meeting – May 28-June 1 in Orlando, Florida.

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More than 50 percent of cancer drugs currently used have originated from natural products. Researchers have received $801,000 from the Florida Department of Health for a project to investigate the use of marine natural compounds as potential treatments of triple negative breast cancers. This form of breast cancer, which represents about 12 percent of breast cancers diagnosed in the U.S., can be very aggressive and easily spread to other organs, particularly the brain and the lungs.

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NIBIB-funded researchers used photoacoustic imaging for rapid measurement of metabolic rate of individual cells from breast tumors—information that can help guide treatment strategies.

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The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) will be holding a complimentary CME program, “Improving Cardiovascular Care in Women and Underserved Populations” on May 30th in New York City. The program is part of a joint initiative called A New Beat which is dedicated to advocating for women and minorities rising as leaders in the field of cardiology, so they can provide better access and improve care for all patients.

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Treating postpartum depression (PPD) in low-income mothers of color requires an understanding of each person’s lived experience, and practitioners should consider interventions that develop broadly from a community level in order to improve outcomes for their clients, according to a University at Buffalo social work researcher.

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Pregnancy-related deaths and serious maternal complications during and after childbirth continue to rise in the United States, with wide variation across hospitals. New research published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA), reports on a new risk-adjusted, composite measure that allows maternal and newborn outcomes to be reported in a single measure. This measure is based on readily available data that are collected by all hospitals and could be used to provide accurate and meaningful feedback on outcomes.

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As células do câncer têm, metaforicamente falando, inúmeros truques na manga para sobreviver frente à quimioterapia, radioterapia e outros tratamentos contra o câncer. Agora, os pesquisadores na Mayo Clinic decifraram um desse truques usando linhagens de células e células de câncer derivadas do paciente.

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A clinical trial underway at Roswell Park Comprehensive Cancer Center will assess a brand-new immunotherapy approach — reprogramming a patient’s blood stem cells to generate a lasting supply of two types of immune cells — in patients with recurrent cancer of the ovaries, fallopian tubes or peritoneum.

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Girls and women face considerable adversity due to the effects of sexism, oppression, discrimination and prejudice, but some are also well-equipped and have the right resources to confront and surmount challenges in their lives, according to psychological practice guidelines released by the American Psychological Association.

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A new finding by researchers at The University of Texas at Dallas and UT Southwestern Medical Center shows that several species of bacteria reside in bladder tissue of postmenopausal women who experience recurrent urinary tract infections (RUTIs).

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The University of Illinois at Chicago will launch a new effort to reduce the health disparities experienced by women and babies living in historically underserved and marginalized communities, thanks to a $4.7 million Healthy Start grant from the Health Resources and Services Administration, or HRSA. Efforts will include leveraging community health workers, social workers and doulas in the Chicago neighborhoods of Auburn-Gresham, Englewood and South Shore to improve health outcomes for pregnant women participating in the program and their children.

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A team of Brazilian researchers has developed a strategy that slows the growth of triple negative breast cancer cells by cutting them off from two major food sources.

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A subpopulation of bone cells releases factors that can halt the growth of breast cancer that’s traveled to the bone, putting the cells in stasis.

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Men who delay starting a family have a ticking “biological clock” — just like women — that may affect the health of their partners and children, according to Rutgers researchers.

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A UT Southwestern study suggests why urinary tract infections (UTIs) have such a high recurrence rate in postmenopausal women – several species of bacteria can invade the bladder walls.

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Uma mastectomia menos invasiva que deixa a superfície da mama intacta se tornou uma opção mais segura para pacientes, incluindo aquelas em que o câncer de mama espalhou para os ganglios linfáticos próximos ou aquelas que têm fatores de risco para complicação cirúrgicas, mostra o estudo da Mayo Clinic.

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50 percent of women miss their postpartum checkup after giving birth. A quality improvement project now has new mothers screened for preeclampsia at their newborn’s pediatric appointments.

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Editor’s Highlights include papers on CRISPR screening, predicting renal toxicity, PAHs and endocrine effects on testicular gap junctions, and vincristine-induced atresia in ovarian follicles

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Experts at Cincinnati Children’s report that the systemic inflammatory process that triggers preterm birth begins in an unexpected location that suggests new ways to develop preventative medications.

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Macrophages in adipose tissue (fat) link obesity to triple-negative breast cancer. Instead of fighting breast cancer, these immune cells actually promote it.

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Below are summaries of recent Fred Hutch research, with links for additional background and media contacts.

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ACSM to release a collection of 14 new pronouncements that present the scientific reviews underlying the updated physical activity guidelines and identify key knowledge gaps for future research in the June issue of Medicine & Science in Sports & Exercise.

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During pregnancy, American Indian mothers are less likely to consume alcohol and no more likely to smoke than white mothers in South Dakota after adjusting for socioeconomic factors.

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In honor of National Women’s Health Week, the REACH Program (Respectful and Equitable Access to Comprehensive Healthcare) at Mount Sinai is hosting a Women’s Health Fair for the Harlem and surrounding communities.

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A less-invasive mastectomy that leaves the surface of the breast intact has become a safe option for more patients, including those whose breast cancer has spread to nearby lymph nodes or who have risk factors for surgical complications, a Mayo Clinic study shows. In the procedure, known as a nipple-sparing mastectomy, surgeons remove breast tissue, leaving the skin, nipple and areola, and immediately rebuild the breasts. The findings are being presented at the American Society of Breast Surgeons annual meeting.

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La mastectomía menos invasiva que conserva intacta la superficie de la mama se ha convertido en una opción segura para más pacientes, incluso para aquellas cuyo cáncer de mama se extendió a los ganglios linfáticos cercanos o tienen factores de riesgo para complicaciones quirúrgicas, revela un estudio de Mayo Clinic.

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Las células cancerosas esconden dentro de sus mangas metafóricas varios trucos para sobrevivir la quimioterapia, la radioterapia y otros tratamientos contra el cáncer. Pero ahora, mediante líneas celulares y células derivadas del cáncer de algunos pacientes, los investigadores de Mayo Clinic descodificaron uno de esos trucos y propusieron una manera de volver a sensibilizar a las células del cáncer de mama al tratamiento.

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Using the mobile app Babyscripts reduced in-person prenatal care visits while maintaining patient and provider satisfaction, according to research published in JMIR mHealth and uHealth by physician researchers from the George Washington University

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A systematic examination of the tumor and the tissue surrounding it — particularly normal cells in that tissue, called fibroblasts — has revealed a new treatment target that could potentially prevent the rapid dissemination and poor prognosis associated with high-grade serous carcinoma (HGSC), a tumor type that primarily originates in the fallopian tubes or ovaries and spreads throughout the abdominal cavity.

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A team of researchers at UCLA's Jonsson Comprehensive Cancer, Cedars-Sinai Cancer Center and Dana-Farber Cancer Institute have newly identified 34 genes that are associated with an increased risk for developing the earliest stages of ovarian cancer.

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Awareness campaign kicking off Myositis Awareness Month aims to ensure the over 75,000 people with the disease are diagnosed and get treated

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Add this to the list of what to expect: Getting up earlier, at least in the first trimester. New research from finds that women and mice both shift their daily schedules earlier by up to a few hours during the first third of their pregnancy. A study by researchers in Arts & Sciences and at the School of Medicine shows how impending motherhood induces changes in daily timing of a mother which, when disrupted, may put a pregnancy at risk, as reported in the Journal of Biological Rhythms.

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Cancer cells have various tricks up their metaphorical sleeves to survive in the face of chemotherapy, radiotherapy and other cancer treatments. Now researchers at Mayo have decoded one of those tricks using cell lines and patient-derived cancer cells, and proposed a way to resensitize breast cancer cells to treatment.

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The findings will enable personalized medicine approaches to disease prediction and potential new therapies for PCOS

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An international group of researchers has taken one of the first major steps in finding the biological changes in the brain that drive fetal alcohol spectrum disorder. New work using chaos theory to analyze brain signals, discussed in the journal Chaos, shows the long-term effects. Researchers found that teenagers who were exposed to alcohol while in the womb showed altered brain connections that were consistent with impaired cognitive performance.

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A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

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An investigational drug that may block harmful antibodies from passing through the placenta of an expectant mother to the fetus is the focus of a new clinical trial led by Kenneth Moise, MD, a maternal-fetal medicine specialist at UTHealth.

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A new study examined APS at the cellular level and found that two drugs reduced development of blood clots in mice affected with the condition.

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Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how “smart” diagnostic-imaging machines identify cancers—and uncovering clues outside the tumor to tell whether a patient will respond well to chemotherapy.

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Many women suffer from premenstrual syndrome, or PMS. But some experience a severe and possibly disabling subset of PMS known as premenstrual dysphoric disorder.

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National Comprehensive Cancer Network to adapt NCCN Guidelines® for Breast, Cervical, and Rectal Cancer to better meet cancer burden and resource levels in Bolivia.

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A new study suggests that Oncotype DX-guided treatment could reduce the cost for the first year of breast cancer care in the U.S. by about $50 million (about 2 percent of the overall costs in the first year). The study by Georgetown Lombardi Comprehensive Cancer Center and National Cancer Institute researchers was published April 24, in JNCI.

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A new study of adults who were referred for evaluation of a suspected sleep disorder suggests that women tend to underreport snoring and underestimate its loudness.