Feature Channels: Dermatology

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ROSEMONT, Ill. (October 4, 2022) — There are many ways to get rid of unwanted facial and body hair, but shaving with a razor is one of the most common and inexpensive methods. Unfortunately, using a razor sometimes can lead to razor bumps, also called shaving bumps. Board-certified dermatologists share simple tips that can help treat this skin condition.

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A clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus those who initially got targeted therapies (52 percent survival rate). Progression-free survival, where the cancer is stable or improving, was also trending in favor of those who started on immunotherapy.

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Hand eczema is one of the most common forms of eczema, causing dry, itchy, and irritated skin affecting the whole hand, including the fingers. This skin condition can negatively impact a person’s quality of life because we use our hands often. In recognition of Eczema Awareness Month in October, board-certified dermatologists share information about the causes of hand eczema and how it can be treated to keep the condition from worsening.

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Two recent UC Davis studies reveal how skin forms differently across different areas of the body from the face and underarms to the palms of our hands and feet. By profiling the changes in skin, researchers found that the differences have a direct impact for how various skin diseases form across the body.

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Apremilast (brand name Otezla) has helped psoriasis patients achieve clearer skin and ease the symptoms of their psoriatic arthritis. Now, new data from researchers at the Perelman School of Medicine at the University of Pennsylvania shows it could also help people with psoriasis shed unhealthy body fat and therefore improve cardiovascular health, a well-known vulnerability for those with psoriasis.

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Researchers from Tel Aviv University deciphered, for the first time, a mechanism that enables skin cancer to metastasize to the brain and managed to delay the spread of the disease by 60% to 80% using existing treatments.

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Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research out of The Wistar Institute now provides evidence of novel, reliable biomarkers that predict therapy response using advanced computer technology.

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The latest research and expert commentary on pain management.

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A team of engineers and doctors at the University of Minnesota Twin Cities have designed a unique 3D-printed light-sensing medical device that could help millions of people worldwide with lupus and other light-sensitive diseases.

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The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. This special edition features upcoming oral presentations by MD Anderson researchers at the European Society for Medical Oncology (ESMO) Congress 2022 focused on clinical advances across a variety of cancer types. Highlights include promising early data from a novel T cell therapy for solid tumors, targeted therapy progress in rare and advanced cancers, biomarkers of immunotherapy response, and features associated with clinical outcomes in leptomeningeal disease. More information on ESMO content from MD Anderson can be found at MDAnderson.org/ESMO.

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In early experiments, Jianjun Guan and his team found that after applying a single dose of their wound dressing into wounds in young diabetic mice, the wounds completely closed at day 14. Wounds that were treated only with the hydrogel or were untreated were reduced to roughly half of their original size.

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Researchers at Sanford Burnham Prebys, led by Ze’ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, these findings could lead to a new class of drugs to selectively treat melanoma, the most severe form of skin cancer.

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The latest research on plants brought to you by Newswise.

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Performed early after surgery, a procedure called microneedling can improve the final appearance of surgical scars – with best results if done within six to seven weeks, reports a study in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

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In a new study published in the Proceedings of the National Academy of Sciences (PNAS), Moffitt Cancer Center used mathematical and computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations.

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Combining techniques in nanotechnology and optics, researchers produced tiny (nanometric) diamond particles so small that they are capable of penetrating skin to deliver medicinal and cosmetic remedies. In addition, they created a safe, laser-based optical method that quantifies nanodiamond penetration into the various layers of the skin and determines their location and concentration within body tissue in a non-invasive manner – eliminating the need for a biopsy.

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The number of atopic dermatitis patients is on the rise. Chula’s dermatologists advise patients and their families to understand the causes of this incurable disease by focusing on making adjustments, reducing the time spent in air-conditioned environments, and avoiding stress and sunlight while keeping the skin moisturized.

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A substance produced by gut microorganisms can lead to scarring and blood vessel damage in patients with scleroderma, a new study suggests. Researchers say they will examine whether drugs or food products, like virgin olive oil, can block the formation of the compound in the gut to treat fibrosis.

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Tattoo inks are unregulated in the U.S. A team has analyzed what is in some inks, and it doesn’t always match what’s on ingredient labels. Once the study is complete, they will publish their results on a website for consumers and tattoo artists. They will present their results at ACS Fall 2022.

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The World Health Organization and the White House have declared the growing monkeypox outbreak a public health emergency, with the Centers for Disease Control and Prevention recommending that people seek medical care immediately if they develop a new, unexplained skin rash or lesion on any part of their body that they think could be monkeypox.

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In a new study published in the Journal of Clinical Oncology, Moffitt Cancer Center physicians, along with a team of international researchers from eight other cancer centers, report on their identification of high-risk patients with stage 3A disease and microscopic lymph node metastases who would benefit from adjuvant therapy.

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The latest research and expert commentary on the monkeypox outbreak.

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Bringing home a new baby is a joyous time for any parent. For first time parents, bringing home a new baby can unlock a wide range of emotions—from excitement to nervousness. As you adjust to parenthood, you’ll notice that your baby has the softest skin, however, you may notice scaly, greasy patches develop on their scalp.

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Ultraviolet (UV) protection from the sun and avoiding indoor tanning play an important role in reducing a person’s risk for skin cancer — the most common cancer in the U.S. and one of the most preventable cancers. A new article published in the reveals that UV protective behaviors are lacking in American Indians/Alaskan Natives, highlighting the importance of educating this population about the need to protect themselves from harmful UV rays.

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Do leaves of three make you itchy? A Penn State Health dermatologist talks about poison ivy – how to avoid it and how to treat the rash.

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The American Academy of Dermatology supports the National Academies of Sciences, Engineering, and Medicine’s recommendation that the U.S. EPA conducts an ecological risk assessment of UV filters to characterize possible risks to aquatic ecosystems and the species that live in them. As the report released today makes clear, the science in this area is limited and inconclusive.

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We rate this claim as mostly true. Among the ways monkeypox can spread is by "Touching objects, fabrics (clothing, bedding, or towels), and surfaces that have been used by someone with monkeypox," according to the Centers for Disease Control and Protection.

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The Burn Center at MedStar Washington Hospital Center admitted its first patient on July 13, 1972. And for a half-century, the Burn Center has provided groundbreaking surgical, critical, and rehabilitative care that has benefited many individuals across the Washington metropolitan region, including firefighters, members of law enforcement, and 10 people injured during the terrorist attacks on the Pentagon on Sept. 11, 2001.

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JMIR Publications recently published "Patients’ Experiences of Telemedicine for Their Skin Problems: Qualitative Study" in JMIR Dermatology which reported that this qualitative study aimed to explore patients’ perceptions of a teledermatology service linking public primary care clinics to the national specialist dermatology clinic in Singapore.

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JMIR Publications recently published "Effectiveness of Pediatric Teleconsultation to Prevent Skin Conditions in Infants and Reduce Parenting Stress in Mothers: Randomized Controlled Trial" in JMIR Pediatrics and Parenting which reported that mothers of infants are prone to experiencing parenting stress, which adversely affects mothers’ and children’s well-being. Additionally, studies have reported that atopic dermatitis (AD) among offspring enhances parenting stress, and postnatal maternal psychological problems can increase the risk of AD in children.

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Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.

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At a time when social media and celebrity icons are driving increased demand for fuller, "pouty" lips, a natural-looking and harmonious appearance of the lips is perceived as most attractive, reports a study in the August issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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Clinical advances include treating hematologic cancers with effective targeted therapies, circulating tumor DNA as a biomarker for recurrence with colorectal liver metastases, and using magnetic resonance imaging (MRI) to guide surgical decisions for patients with lateral pelvic lymph node metastases in rectal cancer. Laboratory findings offer new understanding of the pancreatic cancer immune microenvironment, melanoma cell states, TP53 mutation status in acute myeloid leukemia (AML), and potential targets for metastatic prostate cancer and GNAS-mutant colorectal cancer.

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Hereditary hair loss, also known as androgenetic alopecia or pattern hair loss, is the most common form of hair loss in both men and women, affecting millions of people worldwide.

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Stress is a part of life. Whether your stressors are small or large, they can impact both your mental and physical well-being.

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MD Anderson and Obsidian Therapeutics announce FDA clearance of an Investigational New Drug Application for the novel TIL therapy OBX-115, developed under a strategic collaboration. The first-in-human Phase I study will be led at MD Anderson.

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People with mild or moderate eczema may gain some relief from their condition by adjusting their diets, but there are important downsides that make diets for eczema not a choice to take lightly, says McMaster University researcher Derek Chu.

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The latest research news in Climate Science on Newswise.

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