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Certain liver cells may help prevent organ rejection after transplant and other conditions, study finds

Mayo Clinic

Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value. The study, published in Liver Transplantation, finds that liver mesenchymal stromal cells have immunoregulatory qualities that make them more effective than similar cells derived from adipose, or fat, tissue and bone marrow.

Channels: Immunology, Kidney Disease, Liver Disease, Transplantation,

Released:
20-Jan-2020 2:25 PM EST

New Drug Prevents Liver Damage, Obesity and Glucose Intolerance in Mice on High-Fat Diet

Georgetown Lombardi Comprehensive Cancer Center

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body’s glucose balance.

Channels: Clinical Trials, Liver Disease, Obesity, Pharmaceuticals, Weight Loss, National Institutes of Health (NIH), Grant Funded News,

Released:
20-Jan-2020 10:50 AM EST
Research Results
Newswise: John Theurer Cancer Center Participating in Early-Phase Study of Immunotherapy-Boosting Treatment

John Theurer Cancer Center Participating in Early-Phase Study of Immunotherapy-Boosting Treatment

Hackensack Meridian Health

Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey are participating in a first-in-patients clinical trial assessing VE800, a novel bacteria-containing therapy, in combination with the immunotherapy drug nivolumab. Laboratory research has suggested that VE800 may enhance the effectiveness of drugs like nivolumab.

Channels: Cancer, Digestive Disorders, Immunology, Liver Disease, Microbiome, OBGYN,

Released:
16-Jan-2020 1:55 PM EST
Research Results
  • Embargo expired:
    15-Jan-2020 5:00 AM EST

Heterogeneity of Liver Cancer Cells Helps Explain Tumor Progression in Patients, Mount Sinai Research Found

Mount Sinai Health System

Many liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect the rate at which the cancer grows, Mount Sinai researchers report. The immune system’s contribution to this heterogeneity can have major clinical implications.

Channels: Cancer, Clinical Trials, Liver Disease, Nature (journal), All Journal News,

Released:
14-Jan-2020 12:05 PM EST
Feature
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Machine keeps human livers alive for one week outside of the body

University of Zurich

Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week.

Channels: Biotech, Cancer, Engineering, Liver Disease, Technology, Transplantation, Nature (journal), All Journal News,

Released:
13-Jan-2020 1:15 PM EST
Research Results
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'Ageotypes' provide window into how individuals age, Stanford study reports

Stanford University School of Medicine

What's your type? That question could gain new meaning, thanks to scientists who've categorized how humans age into different classes dubbed "ageotypes," reports a new study from the Stanford University School of Medicine.

Channels: Aging, Autoimmune Diseases, Cell Biology, Genetics, Immunology, Kidney Disease, Liver Disease, Nature (journal), All Journal News,

Released:
13-Jan-2020 12:50 PM EST
Research Results
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NUS and A*STAR scientists identify promising liver cancer-killing compounds with novel drug-screening platform

National University of Singapore

Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)’s Genome Institute of Singapore (GIS) have discovered four potential drug compounds that target hepatocellular carcinoma (HCC), the most common type of liver cancer.

Channels: All Journal News, Cancer, Liver Disease,

Released:
29-Dec-2019 9:05 PM EST
Research Alert
Newswise: UTHealth’s Cynthia Ju awarded NIH grants for liver injury research

UTHealth’s Cynthia Ju awarded NIH grants for liver injury research

University of Texas Health Science Center at Houston

Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

Channels: Liver Disease, Pharmaceuticals, Surgery, Grant Funded News, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH),

Released:
20-Dec-2019 10:50 AM EST
Research Results


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