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Medicine

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Transplant

NewYork-Presbyterian/Weill Cornell Medical Center and Weill Cornell Medicine Launch Living Donor Liver Transplant Program

To expand access to life-saving liver transplants for those in need, NewYork-Presbyterian/Weill Cornell Medical Center and Weill Cornell Medicine have unveiled a new living donor liver transplant program. It performed its first such transplant with success in late January.

Medicine

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Regenerative Medicine, Liver Transplantation, Liver Disease, Drug Testing

Scientists Create Most Sophisticated Human Liver Model Yet

Scientists have developed the most sophisticated mini-livers to date. These organoids can potentially help scientists better understand certain congenital liver diseases as well as speed up efforts to create liver tissue in the lab for transplantation into patients.

Medicine

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Ut Southwestern, Liver, Cancer

Study Shows Liver Cells with Whole Genome Duplications Protect Against Cancer

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Researchers at the Children’s Medical Center Research Institute (CRI) at UT Southwestern have discovered that cells in the liver with whole genome duplications, known as polyploid cells, can protect the liver against cancer.

Medicine

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Ut Southwestern, Liver Cancer

Blood Test Plus Ultrasound Boosts Liver Cancer Detection by 40 Percent

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Combining ultrasound imaging with a blood test for high alpha fetoprotein (AFP) levels improves detection of early-stage liver cancer by as much as 40 percent, researchers at UT Southwestern’s Simmons Cancer Center found.

Medicine

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Bioengineer, Stem Cells, Induced Pluripotent Stem Cells, Transplant, Gastro Intestinal, Gastrointestinal, Tissue Engineering, Stem Cell Reports, Cincinnati Children's Hospital Medical Center, Yokohama City University, Pediatrics, Fatty Liver Disease, press release, News Media

Search for Genetically Stable Bioengineered Gut and Liver Tissue Advances

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Before medical science can bioengineer human organs in a lab for therapeutic use, two remaining hurdles are ensuring genetic stability—so the organs are free from the risk of tumor growth—and producing organ tissues of sufficient volume and size for viable transplant into people. Scientists report in Stem Cell Reports achieving both goals with a new production method for bioengineered human gut and liver tissues.

Medicine

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Douglas Mogul, Pediatric, Liver Transplant, Organ

Alternatives to Whole Liver Transplants for Children Have Become Safer, Study Finds

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In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly.

Medicine

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Hepatitis B, Drug Development, capsid assembly, Liver Cancer, Liver Failure, Cancer, molecular biochemistry, Virology

IU Advances Fight Against Hepatitis B with 'Virus-Cracking' Molecules

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Indiana University researchers have found that certain molecules -- several of which are currently under clinical trial -- are able to "crack" the protective shell of the hepatitis B virus, suggesting it may be possible to attack the virus after its already taken hold in the body. There is currently no cure for the virus, which can cause liver failure and cancer.

Medicine

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Pregnancy, intrahepatic cholestasis of pregnancy, Pregnancy Complications, Liver Disease, still birth, Preterm Birth, Itching

$1.19 Million for Rare Liver Disorder in Pregnancy

The University of Adelaide will lead an international, multi-centre project to help find the best treatment for a rare pregnancy complication that can cause increased risk of preterm and still birth, and considerable distress.

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Emerging Drug Could Help Treat a Common Liver Disease

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Treating a liver disease called NASH (non-alcoholic steatohepatitis) is difficult. Now scientists believe they have found a pharmacologic approach that may inhibit NASH, and thus stop deadly conditions that result from NASH.

Medicine

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Liver Disease

New Guidelines Aim to Prevent Medics From Failing to Diagnose Patients with Liver Disease

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New recommendations, led by experts at the University of Birmingham, have been published to improve the use of liver blood tests.


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