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Article ID: 708096

Cost-Effectiveness Opinions by French National Health Authority Improved Pricing Decisions

ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, the official journal of ISPOR, announced the publication of new research showing that the use of cost-effectiveness opinions issued by the French National Health Authority improved the information available to support the pricing decisions for new hepatitis C drugs.

Released:
18-Feb-2019 3:35 AM EST
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Article ID: 707958

Numares, Mayo Clinic Laboratories announce collaboration to develop new diagnostic tests using distinctive nuclear magnetic resonance technology

Mayo Clinic

Numares and Mayo Clinic Laboratories have announced a collaboration to develop clinical diagnostic tests that will measure clusters of risk factors as opposed to individual biomarkers. The unique testing will use nuclear magnetic resonance (NMR) technology, focusing on cardiovascular disease, kidney disease and liver cancer — among a few other specific diseases.

Released:
12-Feb-2019 11:00 AM EST
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  • Embargo expired:
    11-Feb-2019 10:00 AM EST

Article ID: 707694

Increases in the Percentage of Alcohol in Beverages may Contribute to Underestimates of the U.S. Drinking Level

Research Society on Alcoholism

There have been dramatic increases in the United States in alcohol-related problems. During the past decade the death rate from all types of alcoholic liver disease increased by more than 40%, alcohol-related emergency department visits increased by 62%, and the prevalence of alcohol use disorder among adults increased by nearly 50%. Despite these increases in alcohol-related morbidity and mortality, there have not been notable increases seen in U.S. per capita alcohol consumption.

Released:
7-Feb-2019 8:05 AM EST

Social and Behavioral Sciences

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Article ID: 707471

Saint Joseph’s University Bioethicist Calls for Safe Injection Sites; Proposes Customized Model for Philadelphia

Saint Joseph's University

University’s nationally-recognized Institute of Clinical Bioethics collaborates with local institutions on newly published paper proposing a model for safe injection sites designed to prevent the deaths of thousands of Philadelphians vulnerable to an opioid overdose.

Released:
4-Feb-2019 12:30 PM EST
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Article ID: 707342

The Medical Minute: Living donors may benefit transplant patients

Penn State Health

For a patient awaiting a new organ – namely a liver or kidney – living donation provides a viable alternative and can often shorten a recipient’s wait time.

Released:
31-Jan-2019 12:05 PM EST
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  • Embargo expired:
    31-Jan-2019 11:00 AM EST

Article ID: 707205

Commonly Used Anti-Rejection Drug Could be Repurposed to Treat Some Liver Cancers

Health Sciences at the University of Pittsburgh

Research in animal models suggest that liver cancers with a mutation in the β-catenin gene could respond to treatment with rapamycin, a commonly used immunosupressant.

Released:
29-Jan-2019 1:30 PM EST
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Article ID: 707318

Research Identifies Pathway Connecting Some ARV Drugs With Liver Disease

University of Kentucky

Research out of the University of Kentucky has identified a potential pathway by which certain ARV drugs -- commonly given to patients with HIV -- give rise to liver disease.

Released:
31-Jan-2019 10:05 AM EST
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Article ID: 706972

Why Liver Transplant Waitlists Might Misclassify High-Risk Patients

Cedars-Sinai

A new study in the journal Gastroenterology reveals that the standard method for ranking patients on the waitlist for lifesaving liver transplantation may not prioritize some of the sickest candidates for the top of the list.

Released:
24-Jan-2019 9:00 AM EST
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Article ID: 706851

Study Shows Low-Sugar Diet Effective in Boys with Nonalcoholic Fatty Liver Disease

University of California San Diego Health

Researchers at University of California San Diego School of Medicine found that a diet low in free sugars (those added to foods and beverages and occurring naturally in fruit juices) resulted in significant improvement in nonalcoholic fatty liver disease (NAFLD) in adolescent boys.

Released:
22-Jan-2019 12:05 PM EST
  • Embargo expired:
    22-Jan-2019 11:00 AM EST

Article ID: 706693

Liver Transplant for Alcohol-Related Liver Disease in U.S.

JAMA - Journal of the American Medical Association

The proportion of liver transplants in the United States for alcohol-associated liver disease increased between 2002 and 2016, with much of the increase associated with a decrease in liver transplant for hepatitis C virus infection because of antiviral therapy. This observational study used data from the United Network for Organ Sharing for all liver transplants during the 15-year period and the national study group consisted of nearly 33,000 patients, including 9,438 patients with a diagnosis of alcohol-associated liver disease. Study findings suggest five-year survival after transplant was lower in patients with alcohol-associated liver disease.

Released:
17-Jan-2019 3:05 PM EST

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