Feature Channels: Clinical Trials

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Released: 14-Jan-2020 12:30 PM EST
Unfruitful: Eating More Produce Will Not Cure, Stop Prostate Cancer
UC San Diego Health

University of California San Diego School of Medicine researchers report that patients with prostate cancer assigned to eat seven or more servings of vegetables and fruits daily saw no extra protection from the increased consumption of micronutrients, running contrary to current thought.

Released: 13-Jan-2020 6:05 PM EST
John Theurer Cancer Center Investigators Report Effectiveness of New Treatment for Refractory Multiple Myeloma
Hackensack Meridian Health

Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey were part of the CANDOR global phase III clinical trial for patients with refractory (persistent) multiple myeloma. The study was selected as the prestigious plenary presentation at the 61st American Society of Hematology (ASH) Annual Meeting, the world's leading conference for hematologic cancers and blood disorders, held in Orlando in December.

Released: 13-Jan-2020 3:25 PM EST
UPMC First in the U.S. to Implant Wireless Retinal Device
Health Sciences at the University of Pittsburgh

UPMC is the first center in the U.S. to implant a wireless retinal device to treat advanced age-related macular degeneration.

Released: 12-Jan-2020 9:05 AM EST
Grant to help UniSA researchers develop personalised cancer treatment
University of South Australia

Personalised cancer treatment is one step closer to becoming a reality for more patients, thanks to a Cancer Council Beat Cancer Project grant awarded to University of South Australia researcher Dr Stephanie Reuter Lange to explore how computer-based modelling can optimise cancer treatment and remove the need for expensive clinical trials.

Released: 9-Jan-2020 8:05 AM EST
University of Colorado Cancer Center named National Pancreas Foundation Center of Excellence
University of Colorado Cancer Center

Due in part to advanced surgical techniques, more effective medicines, and a multidisciplinary approach to treating the disease, University of Colorado Cancer Center is able to operate on 30+ percent of pancreatic cancer patients, nearly double the national average.

7-Jan-2020 12:00 AM EST
Penn Medicine Shows Giving Entire Course of Radiation Treatment in Less Than a Second is Feasible
Perelman School of Medicine at the University of Pennsylvania

Cancer patients may one day be able to get their entire course of radiation therapy in less than a second rather than coming in for treatment over the course of several weeks, and researchers in the Abramson Cancer Center of the University of Pennsylvania have taken the first steps toward making it a reality

Released: 7-Jan-2020 1:50 PM EST
Zinc, Folic Acid Supplements Fail to Enhance Male Fertility
University of Utah Health

Zinc and folic acid, a pair of dietary supplements long touted as an effective treatment for male infertility, failed to improve pregnancy rates, sperm counts, and sperm potency in a new study conducted at University of Utah Health and other medical centers in conjunction with the National Institutes of Health. According to the researchers, the finding presents the most definitive evidence to date that so-called fertility supplements do not live up expectations.

3-Jan-2020 3:55 PM EST
Dana-Farber Cancer Institute to Establish Chen-Huang Center for EGFR Mutant Lung Cancers
Dana-Farber Cancer Institute

Dana-Farber Cancer Institute will create the Chen-Huang Center for EGFR (epidermal growth factor receptor) Mutant Lung Cancers to stimulate research, promote clinical trials, and strengthen the Institute’s capabilities for studying and treating lung cancer.

Released: 6-Jan-2020 5:05 PM EST
Can the flu shot help fight cancer?
RUSH

Physicians and scientists at Rush University Medical Center have found that injecting tumors with influenza vaccines, including some FDA-approved seasonal flu shots, turns cold tumors to hot, a discovery that could lead to an immunotherapy to treat cancer. The study results were published December 30th in the Proceedings of the National Academy of Sciences.

Released: 6-Jan-2020 4:35 PM EST
AATS Releases Statement on Transparency of Clinical Research Data
American Association for Thoracic Surgery (AATS)

In response to continued discussion on the validity of the conclusions of the EXCEL trial, The American Association for Thoracic Surgery (AATS) has released a statement calling for the release of all trial data.

Released: 6-Jan-2020 11:50 AM EST
University of Rhode Island, BayCare and Butler Hospital team up to test retinal scanning for early detection of Alzheimer's disease
University of Rhode Island

The five-year, $5 million Atlas of Retinal Imaging in Alzheimer’s Study (ARIAS) is sponsored by BayCare Health System’s Morton Plant Hospital and St. Anthony’s Hospital and funded largely by Morton Plant Mease Health Care Foundation and St. Anthony’s Hospital Foundation in Pinellas County, Florida.

   
Released: 6-Jan-2020 10:20 AM EST
Novel Research That Could Advance Testing, Treatment for Concussions Showcased in the January Issue of AACC’s The Journal of Applied Laboratory Medicine
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

In a special brain health collection, AACC’s The Journal of Applied Laboratory Medicine highlights the innovative clinical tests that laboratory medicine experts are developing to improve care for concussions.

1-Jan-2020 8:55 AM EST
Some genetic sequencing fail to analyze large segments of DNA
UT Southwestern Medical Center

Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical Center.

Released: 3-Jan-2020 4:35 PM EST
Eine Studie hat ergeben, dass eine weniger aggressive Chemotherapie nach der Erstbehandlung von metastasiertem Kolorektalkarzinom vorteilhafter ist
Mayo Clinic

Ein Studie von Mayo Clinic an 5540 Patienten mit metastasiertem kolorektalem Karzinom hat ergeben, dass für Patienten, deren Krankheit unter Kontrolle ist, eine Erhaltungs-Chemotherapie nach der Erstbehandlung nützlicher als eine aggressivere Behandlung ist.

Released: 3-Jan-2020 4:05 PM EST
研究发现转移性结直肠癌初始治疗后转用温和化疗更有益
Mayo Clinic

项在5,540名转移性结直肠癌患者中进行的Mayo Clinic研究发现,对于病情得到控制的患者而言,在初始治疗后进行维持化疗比激进治疗更有益。

Released: 3-Jan-2020 3:45 PM EST
Une étude révèle qu’une chimiothérapie moins agressive après un traitement initial du cancer colorectal métastatique est plus bénéfique
Mayo Clinic

Une étude de Mayo Clinic portant sur 5 540 patients atteints d'un cancer colorectal métastatique révèle que la chimiothérapie d’entretien réalisée après le traitement initial est plus bénéfique pour les patients dont la maladie est sous contrôle, par rapport à un traitement plus agressif.

Released: 3-Jan-2020 3:40 PM EST
Estudo descobre que quimioterapia menos agressiva após o tratamento inicial de câncer colorretal metastático é mais benéfica
Mayo Clinic

Um estudo da Mayo Clinic que envolveu 5.540 pacientes com câncer colorretal metastático revelou que a quimioterapia de manutenção após o tratamento inicial é mais benéfica para pacientes cuja doença está sob controle, em contraste com um tratamento mais agressivo.

Released: 3-Jan-2020 3:20 PM EST
دراسة تكتشف أن العلاج الكيميائي الأقل شدة يعود بفائدة أكبر بعد المعالجة الأولية لسرطان القولون والمستقيم النقيلي
Mayo Clinic

اكتشفت دراسة أجرتها Mayo Clinic شملت 5540 مريضًا من مرضى سرطان القولون والمستقيم النقيلي أن تلقي علاج المداومة الكيميائي بعد المعالجة الأولية كان أكثر فائدة للمرضى الذين يعانون من مرض يمكن السيطرة عليه، مقارنةً بالمزيد من العلاج المكثف

Released: 3-Jan-2020 3:05 PM EST
Estudio descubre que quimioterapia menos agresiva después del tratamiento inicial del cáncer colorrectal metastásico es más beneficiosa
Mayo Clinic

Un estudio de Mayo Clinic que abarcó a 5540 pacientes con cáncer colorrectal metastásico descubre que la quimioterapia de mantenimiento después del tratamiento inicial es más beneficiosa para los pacientes cuya enfermedad está bajo control que el tratamiento más agresivo.

Released: 3-Jan-2020 8:05 AM EST
Drug Trial Seeking First Ever Treatment for Dangerous Side Effect of Prader-Willi Syndrome
Michigan Medicine - University of Michigan

A worldwide research effort is underway for finding a treatment option for hyperphagia, the most common genetic cause of life-threatening childhood obesity.

Released: 2-Jan-2020 1:15 PM EST
Alzheimer 'tau' protein far surpasses amyloid in predicting toll on brain tissue
University of California, San Francisco (UCSF)

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center.

Released: 31-Dec-2019 11:00 AM EST
Trial Suggests Babies in Intensive Care Can be Better Protected From Parental Bacteria
Johns Hopkins Medicine

For sick or prematurely born babies spending their first days of life in a hospital’s neonatal intensive care unit (NICU), the soothing voice and gentle touch of a loving parent can have a tremendous impact toward a positive outcome — that is, unless mom or dad’s visit leaves the infant with something extra: a dangerous bacterial infection.

Released: 26-Dec-2019 11:50 AM EST
Yale Cancer Center launches Center for Community Engagement and Health Equity
Yale Cancer Center/Smilow Cancer Hospital

Yale Cancer Center (YCC) announces the launch of the Center for Community Engagement and Health Equity (CEHE). Building on YCC’s longstanding commitment to high-quality, expert, and patient-centered cancer care, screening, and prevention across the state of Connecticut, the new Center is dedicated to ensuring cancer health equity and improving outcomes with an emphasis on traditionally underserved neighborhoods.

Released: 26-Dec-2019 10:10 AM EST
U-M Approach Could Improve the Accuracy of Cancer Clinical Trials
Michigan Medicine - University of Michigan

An innovative approach to analyzing the medical scans of patients in clinical trials could help ensure the accuracy of trial results while reducing the workload for busy oncologists, according to a new study by researchers at the University of Michigan Rogel Cancer Center.

23-Dec-2019 11:00 AM EST
Proton Therapy Lowers Risk of Side Effects in Cancer Patients Compared to Traditional Radiation
Perelman School of Medicine at the University of Pennsylvania

Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical

Released: 20-Dec-2019 4:45 PM EST
New study shows pregnant women with HIV often not given recommended treatment
Ann and Robert H. Lurie Children's Hospital of Chicago

Pregnant women living with HIV don’t always receive antiretroviral medications recommended for use in pregnancy, according to a recent study published in Jama Network Open this week. Ann & Robert H. Lurie Children's Hospital of Chicago’s researchers collaborated in the multi-site Surveillance Monitoring for ART Toxicities (SMARTT) study of the Pediatric HIV/AIDS Cohort Study (PHACS) network.

Released: 20-Dec-2019 1:10 PM EST
Saint Louis University’s Enrico Di Cera Honored by AAAS
Saint Louis University Medical Center

Saint Louis University’s Enrico Di Cera, M.D., has been named a Fellow of the American Association for the Advancement of Science (AAAS) for his distinguished contributions to science.

Released: 20-Dec-2019 10:25 AM EST
GB Sciences Announces Outstanding Results from Preclinical Study of Its Parkinson's Disease Formulations
GB Sciences, Inc.

GB Sciences, Inc. (OTCQB: GBLX) announced significant preclinical results for their Parkinson's disease ("PD") formulations from the midterm report for their preclinical study being performed by Dr. Lee Ellis of the National Research Council (NRC) in Halifax, Nova Scotia, CANADA.

Released: 20-Dec-2019 10:15 AM EST
Clinical trials planned for brain tumor ‘GPS’ maps
Case Western Reserve University

A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real time with patients at Cleveland Clinic under a three-year, $600,000 V Foundation grant.

16-Dec-2019 1:45 PM EST
Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial
Mayo Clinic

A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenance chemotherapy after initial treatment is more beneficial for patients whose disease is under control, compared with more aggressive treatment.

19-Dec-2019 10:00 AM EST
Researchers Identify Potential Formula for Blood Cancer Vaccine
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.

Released: 19-Dec-2019 9:45 AM EST
Backed by Yale Cancer Center research, FDA approves new drug for advanced bladder cancer
Yale Cancer Center/Smilow Cancer Hospital

The U.S. Food & Drug Administration (FDA) granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

Released: 18-Dec-2019 4:20 PM EST
Battery-powered headgear could short-circuit joint pain
University of Texas Health Science Center at Houston

Tired of living with painful arthritic knees, 54-year-old Deborah Brown’s interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).

Released: 18-Dec-2019 3:10 PM EST
Alzheimer's study shows promise in protecting brain from tau
University of Washington School of Medicine

In the search for an Alzheimer’s cure, the scientific community has focused on drugs to lessen the buildup of amyloid protein in the brain. But new research published today in Science Translational Medicine finds that targeting tau pathology shows promise.The discovery came by looking at what could make worms resistant to pathological tau protein. That’s when researchers discovered the role of the MSUT2 gene. The latest study applied to mice as well. And held true in autopsy samples of Alzheimer's patients.

Released: 17-Dec-2019 12:20 PM EST
First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis
University of North Carolina School of Medicine

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis (OA). Principal investigator of the study, Ari Isaacson, MD, clinical associate professor of vascular and interventional radiology in the UNC School of Medicine, says the results are positive.

Released: 16-Dec-2019 5:05 PM EST
Thomas Gajewski receives immuno-oncology award from ESMO
University of Chicago Medical Center

The European Society for Medical Oncology (ESMO) has named Thomas Gajewski, MD, PhD, Abbvie Foundation Professor of Cancer Immunotherapy in the Ben May Department for Cancer Research and Professor of Pathology and Medicine at the University of Chicago, as the recipient of the 2019 ESMO Immuno-Oncology Award for his groundbreaking work uncovering why some patients are resistant to immunotherapy and how to restore the anti-cancer immune response.

Released: 16-Dec-2019 11:40 AM EST
Elizabeth Fox, M.D., named senior vice president of clinical trials research
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital announced today that Elizabeth Fox, M.D., has been named senior vice president of clinical trials research.

Released: 16-Dec-2019 11:05 AM EST
Novel drug purified and developed from Amazon rainforest tree sap being studied for treatment of chronic diarrhea
University of Texas Health Science Center at Houston

A drug purified and developed from the sap of a tree in the Amazon rainforest is now being studied for the treatment of chronic idiopathic diarrhea in non-HIV patients at The University of Texas Health Science Center at Houston (UTHealth) as part of a two-year pilot study.

12-Dec-2019 12:05 PM EST
Nilotinib Appears Safe In Parkinson’s Trial; Drug Thought to Allow Dopamine Replenishment
Georgetown University Medical Center

A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson’s disease finds that it is reasonably safe and well tolerated. Researchers also report finding an increase in dopamine, the chemical lost as a result of neuronal destruction, and a decrease in neurotoxic proteins in the brain among study participants. Finally, they say nilotinib, a tyrosine kinase inhibitor, potentially halts motor and non-motor decline.

13-Dec-2019 1:10 PM EST
Asthma severity linked to microbiome of upper airway
Washington University in St. Louis

A new study led by Washington University School of Medicine in St. Louis suggests there is a link between bacteria that live in the upper airway and the severity of asthma symptoms among children with mild to moderate asthma.

Released: 12-Dec-2019 8:30 AM EST
Clinical Research Pathways Partners with WellStar Health System to Increase Diversity in Clinical Trials
Clinical Research Pathways

Clinical Research Pathways, an Atlanta-based non-profit, announces a grant to Wellstar Health System designed to increase diversity in oncology-related clinical trials

Released: 11-Dec-2019 1:40 PM EST
Jersey Shore University Medical Center Receives Re-Accreditation from the National Accreditation Program for Breast Centers
Hackensack Meridian Health

Hackensack Meridian Health Jersey Shore University Medical Center achieved re-accreditation from the National Accreditation Program for Breast Centers (NAPBC), a program administered by the American College of Surgeons.

Released: 10-Dec-2019 4:50 PM EST
Relato de caso: Células-tronco são um passo em direção à melhoria da função sensorial motora após lesão medular
Mayo Clinic

As células-tronco derivadas da gordura de um paciente oferecem um passo para melhorar - e não apenas estabilizar - a função motora e sensorial de pessoas com lesões na medula espinhal, de acordo com pesquisas anteriores da Mayo Clinic.

Released: 10-Dec-2019 4:05 PM EST
تقرير حالة: الخلايا الجذعية خطوة نحو تحسين الحركة والوظائف الحسية بعد إصابة الحبل النخاعي
Mayo Clinic

تقدم الخلايا الجذعية المأخوذة من دهون المريض خطوة نحو تحسين - وليس مجرد استقرار - في الحركة والوظائف الحسية لمن يعانون من إصابات في الحبل النخاعي، وذلك وفقًا لبحث أولي أجرته Mayo Clinic.

Released: 10-Dec-2019 3:40 PM EST
Umsom Researchers to Test Vaccine Designed to Protect Against Serious Illness From Contaminated Food and Water
University of Maryland School of Medicine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli (ETEC), and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

Released: 10-Dec-2019 11:35 AM EST
Mayo Clinic, W. L. Gore & Associates announce Avobis Bio, a joint venture for new regenerative therapies
Mayo Clinic

Mayo Clinic and W. L. Gore & Associates Inc., a global materials science company, have formed a joint venture to advance the development of implantable cell therapies to treat debilitating conditions with no cure. Avobis Bio will combine Mayo Clinic's clinical and cell expertise and Gore’s expertise in material sciences to address some of the most challenging medical issues.

9-Dec-2019 12:00 AM EST
Giving Common Antibiotic Before Radiation May Help Body Fight Cancer
Perelman School of Medicine at the University of Pennsylvania

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy

9-Dec-2019 10:50 AM EST
Yale Cancer Center study suggests new approaches needed to manage ibrutinib-related toxicities in CLL patients
Yale Cancer Center/Smilow Cancer Hospital

New findings by Yale Cancer Center (YCC) and Smilow Cancer Hospital researchers show that as the use of the drug ibrutinib climbs in patients with chronic lymphocytic leukemia (CLL), so do the rates of patients who stop taking the drug.

Released: 9-Dec-2019 2:45 PM EST
Research at Argonne's Advanced Photon Source leads to new Ebola drug
Argonne National Laboratory

Scientists using specialized beamlines at Argonne's Structural Biology Center (SBC), a facility for macromolecular crystallography at the Advanced Photon Source, derived insights that led to the discovery of a promising new drug for Ebola.

   


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