Curated News: National Institutes of Health (NIH)

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Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds — and possibly streamline the diagnosis and treatment of gliomas, a study suggests. The newly developed system, DeepGlioma, identified mutations used by the World Health Organization to define molecular subgroups of diffuse glioma with an average accuracy over 90%.

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Dr. Pani's research has the potential to significantly impact the health and well-being of border communities.

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A remoção cirúrgica de ambos os ovários está associada a um risco aumentado de Doença de Parkinson e parkinsonismo em mulheres com menos de 43 anos, conforme relatam os pesquisadores da Mayo Clinic na revista médica JAMA Network Open.

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La extirpación quirúrgica de ambos ovarios se asocia con un mayor riesgo de enfermedad de Parkinson y parkinsonismo en mujeres menores de 43 años, informan los investigadores de la Mayo Clinic en JAMA Network Open.

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In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

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The cystic fibrosis transmembrane conductance regulator has been studied for years but the combined efforts of St. Jude Children’s Research Hospital and Rockefeller University have yielded new insights.

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UC San Diego researchers describe why SARS-CoV-2 subvariants spread more rapidly than the original virus strain, and how an early treatment might have made people more susceptible to future infections.

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New research led by Washington University School of Medicine in St. Louis identifies a common genetic signature that may increase a person's risk of developing substance use disorders. The work eventually could lead to universal therapies to treat multiple substance use disorders and potentially help people diagnosed with more than one.

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Roughly one million people die of untreated kidney failure, worldwide, each year. Despite the major personal and economic burden, only a few new approaches have been deployed to treat or cure kidney disease over the last 40 years.

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A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2. It proved as effective as vaccines administered by injection or intranasally in the research. If ultimately approved for human use, it could be a weapon against all COVID-19 variants and boost uptake, particularly in low- and middle-income countries, and among those with an aversion to needles.

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In a new study, University of California, Irvine researchers found that exposure to the compound tetrahydrocannabinol (THC), a component of cannabis, at a young age could lead to depleted ovarian follicles and matured eggs in adulthood by nearly 50 percent.

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Albert Einstein College of Medicine and Montefiore Health System have received a seven-year, $30 million grant from the National Institutes of Health (NIH) to continue support for the Harold and Muriel Block Institute for Clinical and Translational Research at Einstein and Montefiore (ICTR). The latest Clinical and Translational Science Award (CTSA) will ensure the ICTR will further its vision to improve health in the Bronx, Westchester, and lower Hudson Valley by accelerating the translation of scientific discoveries into effective and equitable prevention and treatment approaches.

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The magnitude and quality of a key immune cell’s response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

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Researchers from the Uniformed Services University (USU) have shed light on a fatal neurodegenerative disease that has long afflicted the native Chamorro people living on Guam – a unique and mystifying disorder that has baffled scientists for decades.

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Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.

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In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

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Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited from the body's own immune system cells: a drastic loss of cancer-fighting fervor known as "exhaustion”.