A Phase III clinical trial involving 101 centers in 21 countries revealed the monoclonal antibody blinatumomab to be more effective than standard chemotherapy for treatment of advanced acute lymphoblastic leukemia (ALL). Study findings were published in the March 1 online issue of the New England Journal of Medicine.
Yale scientist Craig M. Crews is the recipient of the 2017 Outstanding Achievement in Chemistry in Cancer Research Award granted by the American Association of Cancer Research (AACR).
Dr. Kerin Adelson discusses the in-house specialty pharmacy at Smilow Cancer Hospital with HemeOnc Today
Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research at the University of Illinois at Chicago.
An experimental gene therapy that turns a patient's own blood cells into cancer killers worked in a major study. Article by the Associated Press.
It’s what’s missing in the tumor genome, not what’s mutated, that thwarts treatment of metastatic melanoma with immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in Science Translational Medicine.
Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.
Fred Hutchinson Cancer Research Center today announced the recipients of the Harold M. Weintraub Graduate Student Award, which recognizes the outstanding achievement of graduate studies in the biological sciences. The thirteen award recipients were chosen by a selection committee of Fred Hutch faculty members and students for the quality, originality and significance of their work, and for representation of a diverse range of research topics.
A research team comprised of members from The University of Kansas Cancer Center, Stowers Institute for Medical Research, and Children’s Mercy are looking at ways to target cancer stem cells to ensure that once a cancer patient goes into remission, they are not at risk of their cancer returning.
The National Comprehensive Cancer Network® (NCCN®), through funding from the NCCN Foundation® and Kidney Cancer Association, has published a German translation of the NCCN Guidelines for Patients®: Kidney Cancer.
• Dairy consumption appears to lower risk for breast cancer • High consumption of yogurt linked to reduced risk of breast cancer • Higher intake of some cheeses tied to slightly increased risk
Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.
After three rounds of competition — one of which involved a public vote — a software tool developed by researchers at Fred Hutchinson Cancer Research Center and the University of Basel to track Zika, Ebola and other viral disease outbreaks in real time has won the first-ever international Open Science Prize.
Choosing among cancer treatments increasingly involves determining whether tumor cells harbor specific, mutated “oncogenes” that drive abnormal growth and that may also be especially vulnerable or resistant to particular drugs. But according to a new study led by UCSF researchers, in the case of the most commonly mutated cancer-driving oncogene, called KRAS (pronounced “kay-rass”), response to treatment can change as tumors evolve, either when a normal copy of the gene from the other member of the matched chromosome pair is lost, or when the cancers cells evolve to produce additional copies of the mutated form of the gene.
Scalp cooling can lessen some chemotherapy-induced hair loss – one of the most devastating hallmarks of cancer – in certain breast cancer patients, according to a new multicenter study from UC San Francisco, Weill Cornell Medicine and three other medical centers. A majority of the study’s patients, all women with stage 1 or 2 breast cancer who underwent scalp cooling, retained more than half of their hair after completing chemotherapy, the investigators learned.
Led by associate professor of pathology and Yale Cancer Center member Don Nguyen, PhD, the researchers analyzed RNA from patients with disease that was limited to the lungs as well as cancers that had spread.
Susan Baserga selected as a finalist for the 2017 Connecticut Technology Council Women of Innovation program
Dr. Cary Gross, a professor of medicine and cancer researcher at Yale University School of Medicine discusses his 80-year-old father's diagnosis with Hodgkin’s disease.
Jeffrey A. Drebin, MD, PhD, has been named the new Chairman of the Department of Surgery at Memorial Sloan Kettering Cancer Center (MSK). Dr. Drebin brings to MSK decades of experience as a world-class surgical oncologist specializing in pancreaticobiliary, upper gastrointestinal and liver surgery.
A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person’s immune system are best suited to fight cancer. The findings will be published February 24 in Science Immunology.
In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.
Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.
MSK researchers used the genome-editing tool CRISPR to create more potent chimeric antigen receptor (CAR) T cells that don't tire as easily when attacking cancer cells. The unexpected findings were published in the journal Nature on February 22 and underscore the potential of genome editing to advance immunotherapy for cancer.
Four Yale School of Medicine researchers have been elected to the prestigious Connecticut Academy of Science and Engineering (CASE).
The Connecticut Academy of Science and Engineering has elected 24 of the state’s leading experts in science, engineering, and technology to membership in the academy, including 11 new members from Yale.
Researchers at The University of Kansas Cancer Center are collaborating on the “lab-on-a-chip,” a testing platform that captures and performs analysis of various biomarkers, which are actively released by tumor cells into blood. Rather than the usual invasive and costly biopsy, the credit-card size devices will screen for circulating markers that are released from cancer cells within patients’ blood.
Melanoma patients’ response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center report at the ASCO-Society for Immunotherapy in Cancer meeting in Orlando.
For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC), hormone maintenance therapy (HMT) may significantly improve survival, according to a new study from researchers at The University of Texas MD Anderson Cancer Center.
In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40% chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors.
In two recent studies, researchers at UC Davis have shown that placental tissue can provide critical information about the epigenetic landscape that influences fetal development.
UKanQuit, a joint inpatient program between the University of Kansas Medical Center and The University of Kansas Hospital, is helping more smokers quit the habit
The New Mexico Senate “Lobos” tip off against the House of Representatives “Aggies” on Wednesday, March 1, at Santa Fe High School. The hotly-contested game is a fun event for those on the court, on the bench and in the stands. But everyone knows that the real opponent is cancer.
Women with early-stage breast cancer who had an intermediate risk recurrence score (RS) from a 21-gene expression assay had similar outcomes, regardless of whether they received chemotherapy, a new study from The University of Texas MD Anderson Cancer finds.
A recent Yale study may have found a new way to fight brain cancer.
An analysis of a patient’s deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.
The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission.
A recent study from the UCSF Center for Translational and Policy Research on Personalized Medicine and the UCSF Helen Diller Family Comprehensive Cancer Center identified opportunities to address the barriers to coverage of hereditary cancer panels, as published in JNCCN.
The first successful randomized trial of its kind provides preliminary evidence that telephone-based smoking cessation counseling given to smokers shortly after undergoing lung cancer screening can be effective at helping people stop smoking.
Molecular Cancer Therapeutics reports on this treatment for hermangiosarcama
A drug given to reduce the side effects of strong post-surgery pain medications resulting in a reduced length of hospital stay for patients who have undergone major gastrointestinal or bladder cancer procedures is found to have similar benefit for some patients undergoing surgery for testicular cancer. An investigator at Rutgers Cancer Institute of New Jersey explored the impact of alvimopan in those patients who underwent RPLND.
A bladder cancer drug discovered and developed at The University of Kansas Cancer Center is set to become its first cancer drug to go from bench to bedside.
Recognizing a critical need to address disparities in cancer care, The University of Texas MD Anderson Cancer Center has been designated as an ECHO superhub for oncology by the ECHO Institute at the University of New Mexico Health Science Center (UNMHSC). MD Anderson is one of just nine ECHO superhub sites in the world and the first focused on oncology.
HIV/AIDS researchers at Fred Hutchinson Cancer Research Center are pioneering efforts across disciplines to advance preventative and curative approaches against the disease.
A team from The University of Texas MD Anderson Cancer Center describes this week in the journal Nature a series of preclinical experiments using patient-derived tumor xenografts (PDXs) and mouse models that point to potential treatments for patients with a rapidly-progressing and resistant subgroup of tumor cells.
Researchers from Memorial Sloan Kettering Cancer Center (MSK) today published a seminal review of the rapidly evolving field of precision oncology, which allows doctors to recommend therapies based on a genetic understanding of a person’s cancer. Appearing in the special cancer-focused February 9 issue of Cell, the article — “Implementing Genome-Driven Oncology” — presents a critically self-reflective but solutions-focused perspective on this approach to cancer treatment.
A single blood test and basic information about a patient’s medical status can indicate which patients with myelodysplastic syndrome (MDS) are likely to benefit from a stem cell transplant, according to new research by scientists at Dana-Farber Cancer Institute.
To celebrate Valentine’s Day, The University of New Mexico Lobo Men’s and Women’s basketball teams are joining forces to honor all those who have beaten breast cancer, still face it, or have lost to it. They plan to hold their Lobos Love Pink basketball games during the same week to raise awareness for breast cancer.
Ludwig researchers discover that circular DNA, once thought to be rare in tumor cells, is actually very common and seems to play a fundamental role in tumor evolution
Immunotherapy has been a game changer for the oncology field, but typical models used to assess the value of cancer treatments don’t take into account the unique characteristics of this therapy, according to experts at the 2016 annual meeting of the Society for Immunotherapy of Cancer (SITC).
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