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Baby’s Breath: A New Way to Study Neonatal Lung Disease

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Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies.

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Clinical Trial Offers New Drug Combo to Fight Lung Cancer

The 1,000 people in New Mexico fighting lung cancer may soon be able to breathe easier. The first of more than 10 new lung cancer clinical trials has just opened under the direction of Yanis Boumber, MD. The phase 3 clinical trial, called “Neptune,” opened January 28. It compares a combination of two immune drugs with standard chemotherapy.

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Rat Study Shows that Renal Denervation Helps to Bring Drug-Resistant Hypertension under Control

Most clinical studies have shown that renal denervation—a procedure that disrupts the nerves in the kidneys and prevents them from relaying signals—can treat drug-resistant hypertension, although a number have shown the procedure to be ineffective. A new study in American Journal of Physiology—Regulatory, Integrative and Comparative Physiology supports that renal denervation can treat hypertension and suggests that failures may be due to incomplete procedure. This research is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program.

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UCLA–Stanford Researchers Pinpoint Origin of Sighing Reflex in the Brain

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A new UCLA-Stanford study has pinpointed two tiny clusters of neurons in the brain stem that are responsible for transforming normal breaths into sighs. The discovery may one day allow physicians to treat patients with breathing disorders.

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Using Steroids Before Late Preterm Delivery Reduces Neonatal Respiratory Problems

Researchers from Columbia University Medical Center and NewYork-Presbyterian have found that using corticosteroids in mothers at risk for late preterm delivery reduced the incidence of severe respiratory complications in their babies.

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Another Smoking-Related Airway Condition Linked to Breathing Issues Discovered

Expiratory central airway collapse may have a stronger connection to underlying lung disease than previously believed. CT scans may make it a valuable biomarker for impending or worsening lung disease.

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Users of Cherry-Flavored E-Cigarettes May Be Exposed to Higher Levels of Respiratory Irritant

An analysis of 145 different electronic-cigarette flavoring products reveals that many e-cigarette users may be exposed to a potentially harmful chemical, benzaldehyde. The highest concentrations were detected in vapor from cherry-flavored products.

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Fiber-Rich Diet May Reduce Lung Disease

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A diet rich in fiber may not only protect against diabetes and heart disease, it may reduce the risk of developing lung disease, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

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Long-Term Exposure to Ozone May Increase Lung and Cardiovascular Deaths

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Adults with long-term exposure to ozone (O3) face an increased risk of dying from respiratory and cardiovascular diseases, according to the study “Long-Term Ozone Exposure and Mortality in a Large Prospective Study” published online ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

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UT Southwestern Researchers Identify Process That Causes Chronic Neonatal Lung Disease

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Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants.

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E-Cigarettes, As Used, Aren’t Helping Smokers Quit, Study Shows

Electronic cigarettes are widely promoted and used to help smokers quit traditional cigarettes, but a new analysis from UC San Francisco found that adult smokers who use e-cigarettes are actually 28 percent less likely to stop smoking cigarettes.

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Lung Cell Found to Act as Sensor, Regulator of Immune Response

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An uncommon and little-studied type of cell in the lungs has been found to act like a sensor, linking the pulmonary and central nervous systems to regulate immune response in reaction to environmental cues. The cells, known as pulmonary neuroendocrine cells or PNECs, are implicated in a wide range of human lung diseases, including asthma, pulmonary hypertension, cystic fibrosis and sudden infant death syndrome, among others.

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Even Children with Higher IQs Behave Better When Their Sleep Apnea Is Fixed

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Many doctors will ask about quality of sleep when children have problems at school, but new research shows it’s just as important to pay attention to how high achievers are sleeping.

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Veterans and Civilian Patients at Risk of ICU-Related PTSD Up to a Year Following Hospital Discharge

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One in ten patients is at risk of having new post-traumatic stress disorder (PTSD) related to their ICU experience up to a year post-discharge. This was the finding from a multicenter, prospective cohort research study of veterans and civilians. The research was published online ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

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Long-Term Ozone Exposure Increases Acute Respiratory Disease Syndrome Risk in Critically Ill Patients

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Critically ill patients who are exposed to higher daily levels of ozone are more likely to develop acute respiratory disease syndrome (ARDS), according to a new study published online ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. ARDS is a life-threatening inflammatory lung illness in which patients fail to obtain enough oxygen to the lungs. While previous research has shown a clear association between cigarette smoke and ARDS, the study “Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome” by Lorraine Ware, MD, of Vanderbilt University School of Medicine and colleagues is the first to demonstrate a risk related to ozone.

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Genetic Variation Linked to Respiratory Disease

A UA researcher and clinician team has discovered that genetic mutations in a protein associated with asthma can affect a person’s susceptibility to a variety of lung diseases — and could lead to new treatments.

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Statins May Lower Risk of Heart Disease in People with Sleep Apnea

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A new study has revealed that cholsterol-lowering statins may help reverse the mechanisms that increase the risk of heart disease in people with sleep apnea.

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Vitamin D Deficiency Does Not Increase Risk and Severity of OSA

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A recent study of elderly men found no evidence that obstructive sleep apnea (OSA) increased in severity (or prevalence) as a result of vitamin D deficiency.

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The Leonard C. Goodman Institute for Investigative Reporting Is Now Accepting Submissions

The deadline for this round of proposals is January 15, 2016. Candidates will be notified of decisions by the end of February 2016. The Institute pays a competitive rate--and covers expenses--for investigative reporting that advances social and economic justice. All stories are published in In These Times magazine and on InTheseTimes.com.

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