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Medicine

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Asthma

Study Shows Combination Drug Therapy for Asthma Patients Is Safe

A post-marketing safety study mandated by the U.S. Food and Drug Administration has shown that a combination drug therapy for the treatment of asthma is safe and effective.

Medicine

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Asthma, Children, Pediatric, Gene, Viral Illness, Respiratory

Study Found a Gene Associated with Asthma in Children Who Had a Viral Illness Early in Life

Results of a study published in PLOS ONE show that asthma risk increased 17 times when children who had bronchiolitis in the first two years of life also had a common variation of the Plasminogen activator inhibitor-1 (PAI-1) gene.

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Nanoparticle That Mimics Salmonella Counteracts Chemotherapy Resistance, Protein’s Role in Cell Division, A Novel MRI Method, and MORE in the Cancer News Source

Click here to go directly to the Cancer News Source

Science

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Tubercolosis, Tuberculosis treatment

Collaborations Pharma, Inc. And Rutgers Announce NIH Award to Develop Treatments for Tuberculosis

The National Institute of Allergy and Infectious Diseases (NIAID) recently awarded $149,388 to Collaborations Pharma, Inc. (CPI) to initiate a partnership with Rutgers aimed at developing a series of compounds for treating tuberculosis (TB).

Medicine

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Lung Cancer, K-ras-induced lung cancer, Rutgers University, Princeton University, New Jersey

Cutting Off the Cancer Fuel Supply

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Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell’s ‘fuel supply’ by targeting a cellular survival mechanism known as autophagy.

Medicine

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Telomerase, Mary Armanios, Emphysema, Pulmonary Fibrosis, Gene, NAF1

New Disease Gene Linked to Telomerase Abnormalities in Some Cases of Pulmonary Fibrosis and Emphysema

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Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis.

Medicine

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LISA, LISA, or Less Invasive Surfactant Administration, Preemies

Best Strategy to Prevent Chronic Lung Disease in Preterm Infants

The study compared seven different ventilation strategies. Based on data collected from 30 different trials and over 5,500 infants younger than 33 weeks’ gestational ag.,

Medicine

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apnea of prematurity, breathing pauses, low oxygenation, Running, Neuromodulation, prematuri, Preemie

Inspired by Evolution: A Simple Treatment for a Common Breathing Problem Among Premature Infants

As humans evolved over many thousands of years, our bodies developed a system to help us when we start running and suddenly need more oxygen. Now, using that innate reflex as inspiration, UCLA researchers have developed a noninvasive way to treat potentially harmful breathing problems in babies who were born prematurely.

Medicine

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Pre-term infants, extremely low birthweight babies, Microbiome, Airway microbiome, Lung Disease, Bronchopulmonary Dysplasia, Lactobacillus, Firmicutes, Proteobacteria, dysbiosis, Neonatal Intensive Care Unit

Discovery of Infants’ Airway Microbiomes May Help Predict Lung Disease

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Researchers have found that the infant airway is already colonized with bacteria when a baby is born — and this is true for infants born as early as 24 weeks gestation. The pattern of colonization appears to have an important link to later severe neonatal lung disease.

Medicine

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Lung Cancer, BMI1, CEBPa, Nsclc, non-small cell lung cancer (NSCLC)

Researchers From CSI Singapore Discover New Way to Inhibit Development of Lung Cancer

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A study led by Professor Daniel Tenen, Director of the Cancer Science Institute of Singapore at the National University of Singapore, found that inhibiting a protein called BMI1 could inhibit the development of lung cancer.

Medicine

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Bidmc, Beth Israel Deaconess, Beth Israel Deaconess Medical Center, Lung Cancer, Lung Cancer Treatment

Researchers Inhibit Tumor Growth in New Subtype of Lung Cancer

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease. A team of investigators led by Elena Levantini, PhD, a research associate in Hematology-Oncology at Beth Israel Deaconess Medical Center (BIDMC), instructor of medicine at Harvard Medical School and a member of the Harvard Stem Cell Institute, have identified a subtype of human adenocarcinoma. The research could help determine which individuals are at greatest risk of developing lung tumors that may be amenable to a new therapy to inhibit their progression.

Medicine

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Guidelines Lungs, guidelines of care, Pulmonary and Respiratory Medicine, Pediatric, Clinical Practice Guidelines, Wheezing

ATS Issues Clinical Practice Guidelines on Diagnosing Persistent Wheeze in Infants

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The American Thoracic Society has issued clinical practice guidelines to help pediatricians and pediatric pulmonologists evaluate infants with recurrent or persistent wheezing. “Official ATS American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing” is published in the Society’s Aug. 1 American Journal of Respiratory and Critical Care Medicine and is available online.

Medicine

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KRAS, Lung Cancer, Ut Southwestern

Scientists Discover New Therapeutic Target for Lung Cancer Driven by KRAS

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UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully.

Medicine

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Revolutionary Surgery Helps Children with Severely Restricted Airways Breathe Without a Tracheostomy

Subcranial rotation distraction is enabling children like Hannah Schow to breathe without a tracheostomy for the first time.

Medicine

Science

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Ut Southwestern, M cells, Tuberculosis, microfold cell

UT Southwestern Researchers Identify New Mechanism of Tuberculosis Infection

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Researchers from UT Southwestern Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore

Medicine

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Medicine & Health, Public Health, Pulmonary and Respiratory Medicine

Beware of Antioxidants, Warns Scientific Review

The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease. Professor Pietro Ghezzi at the Brighton and Sussex Medical School and Professor Harald Schmidt at the University of Maastricht have analyzed the evidence behind this. The result is a clear warning: do not take these supplements unless a clear deficiency is diagnosed by a healthcare professional.

Medicine

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Sepsis, Critical Care, ARDS, Lung Failure, Microbiome, dysbiosis, ICU

What Are Gut Bacteria Doing in Critically Ill Lungs? New Discovery Could Change ICU Care

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No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients.

Medicine

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Rhinovirus, cold, Asthma, Children, Respiratory, Viruses

UW, Purdue Scientists Solve Structure of Cold Virus Linked to Childhood Asthma

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The atomic structure of an elusive cold virus linked to severe asthma and respiratory infections in children has been solved by a team of researchers at the University of Wisconsin–Madison and Purdue University. The findings provide the foundation for future antiviral drug and vaccine development against the virus, rhinovirus C.

Medicine

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Oncology, Cancer, Surgery, Pulmonanry

Revolutionary Surgery for Lung Cancer

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The University of Montreal Hospital Research Centre (CRCHUM) is launching a major international clinical trial to test a minimally invasive and safer surgical approach for patients with lung cancer: video-assisted thoracoscopic (VATS) lobectomy with ultrasonic pulmonary artery sealing.

Medicine

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heart lung machine, Transplant, Intensive Care, ECMO, Extra Corporeal Lung Support

Rush Is First to Receive Honor for Excellence in Life Support Using Temporary, Mechanical Assistance for Heart, Lung Functions

Rush University Medical Center received the ELSO Award for Excellence in Life Support – the most prestigious designation in critical care by the Extracorporeal Life Support Organization. Rush is the only full service adult and pediatric academic medical center in Chicago and Illinois to receive the Designated Gold Level Center of Excellence designation.







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