Therapy that involved bone marrow stem cells did not improve cardiac function in patients following a heart attack, according to a study.
Researchers have shown that endocrine progenitor stem cells exist in the adult human pancreas, and they have demonstrated that these stem cells can be transformed into insulin-producing cells.
A study has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells.
Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves.
A new study published this week in the Proceedings of the National Academy of Sciences online Early Edition provides compelling visual evidence that hematopoietic, or blood-forming, stem cells prefer a solitary life.
New study may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease. Researchers found that the sympathetic nervous system plays a critical role in coaxing bone marrow stem cells into the bloodstream.
Researchers in the lab of Whitehead Institute Member and MIT professor of biology Harvey Lodish have discovered a way to multiply an adult stem cell 30-fold, an expansion that offers tremendous promise for treatments such as bone marrow transplants and perhaps even gene therapy.
Analyzing the complete gene-expression profiles of both cloned and fertilization-derived stem cells in mice, scientists at Whitehead Institute for Biomedical Research now have concluded that the two are indistinguishable.
Scientists have developed a precisely defined stem cell culture system free of animal cells and used it to derived two new human embryonic stem cell lines.
This research is the first to demonstrate a way to genetically correct sickle cell disease using RNA interference. The technique should be broadly applicable to use therapeutically in stem cells or malignant cells.
Working with heart attack-stricken mice, a team of University of Wisconsin-Madison scientists has shown that embryonic stem cells may one day live up to their clinical promise.
UW-Madison scientists have found a new way to sneak drugs past the blood-brain barrier by engineering and implanting progenitor brain cells derived from stem cells to produce and deliver a critical growth factor that has already shown clinical promise for treating Parkinson's disease.
In a series of experiments in animals, researchers at Johns Hopkins have successfully used a technique that tracks mesenchymal stem cells via magnetic resonance imaging (MRI) to monitor the progress of the cells in repairing tissue scarred by heart attack.
A new study suggests that stem cells act as construction supervisors, directing the work of other cells, rather than doing the heavy lifting themselves.
New experiments that prevented rat sperm stem cells from changing permanently into sperm have brought researchers one step closer to coaxing such cells to behave like embryonic stem cells, capable of growing into many other types of cells in the body.
Stem cells derived from human heart tissue develop into multicellular, spherical structures called cardiospheres that express the normal properties of primitive heart tissue, smooth muscle and blood vessel cells, according to a study by Johns Hopkins researchers.
A single cell with the potential to repair damaged heart muscle tissue...regenerate injured bone...create new cartilage or skin...even reverse nerve damage. Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.
Stem Cell Research 101 is a one-day primer on the science, ethics and politics of stem cell research for policymakers, journalists and interested citizens. Tuesday, Nov. 15, in Washington, D.C.
Scientists at the Salk Institute for Biological Studies have identified a crucial cellular signal that controls the fate of stem cells in the brains of adult mice.
Researchers have discovered the presence of functional ion channels in human embryonic stem cells. These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become all cell types of the body, to conduct and pass along electric currents.
Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital.
An encouraging study has shown that transplantation of bone marrow stem cells into the heart improves heart function and blood flow in heart attack patients for up to six months.
Scientists at Whitehead Institute for Biomedical Research have successfully demonstrated that a theoretical"”and controversial"”technique for generating embryonic stem cells is indeed possible.
A Children's Hospital Boston surgeon has isolated fetal cells from amniotic fluid (mesenchymal stem cells, a generation removed from embryonic stem cells) and used them to grow new tracheal tissue to repair a congenital tracheal defect in utero.
Researchers working with human embryonic stem cells have uncovered the process responsible for the single-most tantalizing characteristic of these cells: their ability to become just about any type of cell in the body, a trait known as pluripotency.
Scott Gilbert's "˜Bioethics and the New Embryology' lays out the science of stem cells and other issues.
A team of scientists has used a non-invasive imaging technique, called SPECT/CT, to successfully trace stem cells' destinations after being injected into the body to treat animal hearts damaged by myocardial infarction, or heart attack.
An international team of researchers has discovered that human embryonic stem cell lines accumulate changes in their genetic material over time.
National and international scientists, including those from the University of Virginia Health System, will announce findings from a significant number of studies showing that adult stem cells from adipose tissue (fat) could eventually be used to treat injured or damaged tissues.
A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.
A University of Dayton research laboratory may hold the key to someday discovering what causes infertility and certain kinds of cancer.
Researchers at UT Southwestern Medical Center have determined that stem cells in a certain region of the brain may be the source of a particular type of incurable brain tumor and may be implicated in other types of brain cancers as well.
Sen. Bill Frist's recent Frist-flop on stem cell research has drawn the ire of his esteemed colleagues who call it fiscally irresponsible to spend scarce federal dollars. But what of the $10 billion for the dysfunctional MDS? Or the billions it will cost to deposit space garbage?
Children with very high-risk acute lymphoblastic leukaemia (ALL) benefit if they receive a blood stem cell transplant from a compatible related donor rather than chemotherapy, according to an article.
Researchers have discovered that a single protein regulates secretion levels in the fruit fly's salivary gland and its skin-like outer layer.
Results of a study show that stem cell therapy can be used effectively to treat heart attacks in pigs. In just two months, stem cells harvested from another pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 percent.
Using nanoparticles, scientists have for the first time delivered genes into the brains of living mice with an efficiency comparable to viral vectors with no observable toxic effect. They also have activated brain stem cells in vivo, potentially to replace those destroyed by disease.
An expert panel of stem cell scientists, primatologists, philosophers and lawyers has concluded that experiments implanting, or grafting, human stem cells into non-human primate brains could unintentionally shift the moral ground between humans and other primates.
Physicians in Sweden and Norway collaborated with USC researchers to successfully produce functioning neurons from adult stem cells harvested from the ventricle area of a donor's brain.
Scientists at the U-M Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells. Called hematopoietic stem cells, they give rise to all the different types of specialized cells in blood.
According to research published today, investigators have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells.
Heart specialists at Johns Hopkins believe they have figured a way around a persistent barrier to successful adult stem cell therapy for millions of Americans who have survived a heart attack but remain at risk of dying from chronic heart failure.
Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells.
Johns Hopkins scientists have developed a way to study the earliest steps of human blood development using human embryonic stem cells grown in a lab dish instead of the embryos themselves.
Regenerative medicine scientists at the University of Florida's McKnight Brain Institute have created a system in rodent models that for the first time duplicates neurogenesis -- the process of generating new brain cells -- in a dish.
Baby and wisdom teeth, along with jawbone and periodontal ligament, are non-controversial sources of stem cells that could be "banked" for future health needs, according to a National Institutes of Health researcher who spoke today at the American Dental Association's national media conference.
New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells. Findings offer new ideas on disease states.
The premature use of stem cell therapy could put many patients at risk of viral or prion diseases unless appropriate safety systems are in place, warn experts.
Researchers in the lab of Whitehead Institute Member Rudolf Jaenisch have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently.
A comprehensive study from Canada's Robarts Research Institute has pinpointed two genes that shed significant light on why stem cells divide and develop less vigorously as we age.
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