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7-Sep-2018 10:05 AM EDT
1 in 4 Older Adults Prescribed a Benzodiazepine Goes on to Risky Long-Term Use, Study Finds
Michigan Medicine - University of Michigan

They may start as well-intentioned efforts to calm anxiety, improve sleep or ease depression. But prescriptions for sedatives known as benzodiazepines may lead to long-term use among one in four older adults who receive them, according to new research. That’s despite warnings against long-term use of these drugs, especially among older people.

Released: 10-Sep-2018 9:40 AM EDT
U-M cancer researcher awarded $6.5M Outstanding Investigator Award to explore precision oncology
Michigan Medicine - University of Michigan

A new grant to University of Michigan Rogel Cancer Center member Arul Chinnaiyan, M.D., Ph.D., will provide long-term support to increase understanding of genetic markers to leverage targeted treatments for cancer.

Released: 10-Sep-2018 9:00 AM EDT
Mayo Clinic se une a otros hospitales en la apertura de una compañía sin fines de lucro para fármacos genéricos
Mayo Clinic

Mayo Clinic se une a la coalición de otros siete hospitales a fin de inaugurar Civica Rx, compañía sin fines de lucro para fármacos genéricos que ayudará a los pacientes a afrontar la escasez y el alto costo de algunos medicamentos que salvan vidas.

6-Sep-2018 5:05 AM EDT
Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals
SLAS

A new review explores how improved safety screening strategies and methods are improving the pharmaceutical discovery and development process. The authors outline several fundamental methods of the current drug screening processes and emerging techniques and technologies that promise to improve molecule selection. In addition, the authors discuss integrated screening strategies and provide examples of advanced screening paradigms.

   
Released: 7-Sep-2018 1:05 PM EDT
Finding That Links ALS/Ataxia to Cellular Stress Opens New Approaches for Treatment
University of Utah Health

Scientists at University of Utah Health report for the first time that a protein, called Staufen1, accumulates in cells of patients suffering from degenerative ataxia or amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.

Released: 7-Sep-2018 10:15 AM EDT
New Flexible Robotic Scope Enables Physicians to Remove Large Colorectal Lesions without Surgery
NYU Langone Health

Robotic scope enables physician to successfully remove lesions that cannot be removed by endoscopy without the patient needing surgery.

Released: 7-Sep-2018 10:05 AM EDT
New Guidelines for Traumatic Brain Injury – Built with Input from Rehabilitation Professionals
Wolters Kluwer Health: Lippincott

Clinical practice guidelines play a critical role in promoting quality care for patients with traumatic brain injury (TBI). A new set of guidelines for rehabilitation of patients with moderate to severe TBI – incorporating insights from the rehabilitation professionals responsible for providing care from initial assessment through long-term follow-up – is introduced in the September issue of the Journal of Head Trauma Rehabilitation (JHTR), official journal of the Brain Injury Association of America. The journal is published in the Lippincott portfolio by Wolters Kluwer.

4-Sep-2018 4:00 PM EDT
NYS Sepsis Reporting Mandate Appears to Improve Care, Reduce Deaths
American Thoracic Society (ATS)

A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who are critically ill, according to a new study published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

Released: 6-Sep-2018 2:05 PM EDT
Dr. Anthony Wynshaw-Boris Elected President of the American Society of Human Genetics
Case Western Reserve University

Anthony Wynshaw-Boris, MD, PhD, the James H. Jewell MD ’34 Professor of Genetics and chair of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center and Rainbow Babies & Children’s Hospital, has been elected as president of the American Society of Human Genetics, the primary professional membership organization for human genetics worldwide.

Released: 6-Sep-2018 2:05 PM EDT
Northwestern Memorial Hospital joins elite group of hospitals to sign relationship-building agreement with the United Arab Emirates
Northwestern Medicine

Northwestern Memorial Hospital has been selected as a preferred provider of exceptional medical care for patients from the United Arab Emirates (UAE.) Northwestern Medicine joins a select network of leading US hospitals, including Mayo Clinic, Johns Hopkins Medicine, and Cleveland Clinic, that will provide specialized care to citizens of the UAE.

Released: 6-Sep-2018 1:05 PM EDT
Penn Extends its Global Reach to Improve Health Care Education and Quality of Care in Southeast Asia
Perelman School of Medicine at the University of Pennsylvania

Penn Medicine and Penn Nursing have launched a formal alliance with the Vingroup – an enterprise that encompasses a newly formed private not-for-profit university project, VinUni, as well as the largest and leading private health service provider in Vietnam, Vinmec – in an effort to improve health care and to create new undergraduate and graduate medical training programs in Vietnam.

Released: 6-Sep-2018 11:05 AM EDT
Mayo Clinic joins hospitals to launch a not-for-profit generic drug company
Mayo Clinic

Mayo Clinic joins a coalition of seven hospitals in launching Civica Rx, a not-for-profit generic drug company that will help patients by addressing shortages and high prices of lifesaving medications. The company, which is organized as a Delaware nonstock, not-for-profit corporation, will be headquartered in Utah.

Released: 6-Sep-2018 10:30 AM EDT
Harvard Medical School Announces 2018 Media Fellows
Harvard Medical School

Harvard Medical School has selected the 2018 fellows for its annual Media Fellowship program, Sept. 24-28. The program, now in its 21st year, brings top health and science journalists together with preeminent researchers and physician-scientists for a weeklong educational immersion.

   
Released: 6-Sep-2018 8:05 AM EDT
Single-Dose Drug Can Shorten Flu Symptoms By About a Day, Studies Suggest
University of Virginia Health System

A single dose of a new influenza drug can significantly shorten the duration of the illness in teens and adults, according to a study published in the prestigious New England Journal of Medicine.

Released: 6-Sep-2018 8:05 AM EDT
Roswell Park Team Identifies Possible Cause of Resistance to Prostate Cancer Treatment
Roswell Park Comprehensive Cancer Center

A Roswell Park-led research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target. Their findings were published in the journal Nature Communications.

Released: 5-Sep-2018 1:30 PM EDT
Multi-Disciplinary Structure Provides Best Care for Maternal Fetal Medicine
University of Arkansas for Medical Sciences

Charlotte and Emelia Dubs are just starting to toddle around their world. The 1-year-old twin girls from Conway spend their days exploring, laughing, blowing kisses and keeping their parents, Kenzie Butcher-Dubs and Morgan Dubs, on their toes.

Released: 5-Sep-2018 1:05 PM EDT
Metabolism-Focused Startup Aims to Shorten Time Between Scientific Insight and Therapies
University of California, Los Angeles (UCLA), Health Sciences

A new “virtual” drug development startup company, Enspire Bio, will channel the knowledge and financial resources necessary to translate basic science — the bedrock of medicine — into powerful treatments. And, in a notable departure from traditional approaches, the translation will occur in the heart of the research lab.

Released: 5-Sep-2018 1:05 PM EDT
UCLA’s epilepsy center offers hope to people with drug-resistant seizures
University of California, Los Angeles (UCLA), Health Sciences

Thirty to 40 percent of people with epilepsy — more than 1 million Americans — continue to experience seizures despite taking medication. Experts at the UCLA Seizure Disorder Center at UCLA Health want to change that picture. Their message to people with epilepsy as well as their doctors is simple: Referral to a full-service epilepsy center can help.

Released: 5-Sep-2018 9:00 AM EDT
Pathologists Confront the Opioid Crisis
College of American Pathologists (CAP)

The CAP releases position statement creating solutions for combating the opioid crisis

4-Sep-2018 8:05 AM EDT
Hypertension Drugs Could Prevent Memory Loss in Lupus Patients, Study Suggests
The Rockefeller University Press

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus (SLE). The study, which will be published September 5 in the Journal of Experimental Medicine, shows that ACE inhibitors—a class of drugs commonly used to treat hypertension—can block this process in mice and might therefore be used to preserve the memory of lupus patients.

31-Aug-2018 11:30 AM EDT
NIH Director Francis S. Collins to Deliver ENDO 2019 Presidential Plenary
Endocrine Society

The Endocrine Society has confirmed the plenary program speaker line-up for ENDO 2019, the world's largest event for endocrine science and medicine. This year features a presidential plenary from Francis S. Collins, M.D., Ph.D., Director of the National Institutes of Health (NIH), the largest supporter of biomedical research in the world. Other noteworthy speakers are Robert Califf, M.D., Duke University School of Medicine and former Food & Drug Administration (FDA) Commissioner, and Cori Bargmann, Ph.D., Rockefeller University and head of the Chan Zuckerberg Initiative’s science work.

Released: 5-Sep-2018 8:05 AM EDT
RxHealth™ Raises $1.8 Million Seed Round, Launches Bulk Prescription™ to Population Health Programs
Mount Sinai Health System

Digital medicine platform Rx.Health, a Mount Sinai Health System spinoff and provider of RxUniverse™, recently announced that it has raised $1.8 million in seed funding.

31-Aug-2018 12:05 PM EDT
Three Outstanding Biomedical Researchers in Life Sciences, Physical Sciences & Engineering, and Chemistry win the 2018 Blavatnik Regional Awards for Young Scientists
Blavatnik Family Foundation/New York Academy of Sciences

The Blavatnik Family Foundation and the New York Academy of Sciences today announced the three winners and six finalists of the 2018 Blavatnik Regional Awards for Young Scientists.

   
Released: 4-Sep-2018 1:05 PM EDT
Three Penn Medicine Gene Therapy Innovators Receive International Award for Pioneering Work to Treat Childhood Blindness
Perelman School of Medicine at the University of Pennsylvania

Three Penn Medicine ophthalmology innovators received the 2018 António Champalimaud Vision Award for their revolutionary work leading to the first successful gene therapy to cure an inherited cause of childhood blindness.

Released: 4-Sep-2018 1:05 PM EDT
Synthetic DNA Technology Provides a Novel Strategy for Effective Delivery of a Complex Anti-HIV Agent
Wistar Institute

Wistar scientists have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics for infectious agents as well as for diverse implications in therapeutic delivery.

Released: 4-Sep-2018 12:05 PM EDT
R.I. Schools Offer Dual Degree in Pharmacy, Physician Assistant Studies
University of Rhode Island

URI Doctor of Pharmacy (PharmD) students can apply to Johnson & Wales’ Master of Science in Physician Assistant Studies (MSPAS) program after completing their fourth year of the six-year pharmacy program. Applications began in the spring.

Released: 4-Sep-2018 11:05 AM EDT
Internationally Renowned Interventional Cardiologist Named to Key Cardiac Posts at NYU Langone Health
NYU Langone Health

Craig A. Thompson, MD, MMSc , whose seminal, pioneering achievements are now a standard of care for re-vascularization of totally blocked coronary arteries, has been named director of cardiac catheterization laboratories at NYU Langone Health System .

Released: 4-Sep-2018 11:05 AM EDT
Department of Defense Grant Awarded to NYU’s Dr. Brian Schmidt and Columbia’s Dr. Nigel Bunnett to Investigate Drugs that Inhibit Receptors in Pain-Sensing Nerves
New York University

The Department of Defense (DoD) has awarded Brian Schmidt, DDS, MD, PhD, director of the Bluestone Center for Clinical Research at New York University College of Dentistry (NYU Dentistry) and Nigel Bunnett, PhD, professor in the Departments of Surgery and Pharmacology at Columbia University, a joint $2.4 million, three-year grant to study how receptors inside nerve cells generate chronic (long-lasting) pain. Three painful medical conditions prevalent in military personnel and veterans—headache, nerve injury, and infectious colitis—will be investigated.

Released: 4-Sep-2018 11:00 AM EDT
Focused Delivery for Brain Cancers
Washington University in St. Louis

Hong Chen, assistant professor of biomedical engineering in the school of Engineering & Applied Science, and assistant professor of radiation oncology at the School of Medicine, reached across disciplines to develop a more focused drug delivery system that can target tumors lodged in the brainstem.

Released: 4-Sep-2018 10:15 AM EDT
NYIT Receives NSF Grant, Aims to Strengthen Regional STEM Innovation
NYIT

Researchers from New York Institute of Technology (NYIT) have secured $426,621 in funding from the National Science Foundation (NSF) for the acquisition of a micro-computed tomography machine.

   
Released: 4-Sep-2018 10:05 AM EDT
Mount Sinai Launches Television Series on CUNY TV
Mount Sinai Health System

The Mount Sinai Health System has launched a new television series called Mount Sinai Future You, featuring clinicians, researchers, and patients discussing how innovations in science, medicine, and new models of care are changing the course of health care.

Released: 4-Sep-2018 9:50 AM EDT
Study: Massachusetts ICU Nurse Staffing Regulations Did Not Improve Patient Mortality and Complications
Beth Israel Lahey Health

In 2014, Massachusetts lawmakers passed a law requiring a 1:1 or 2:1 patient-to-nurse staffing ratio in intensive care units (ICU) in the state, as guided by a tool that accounts for patient acuity and anticipated care intensity. The regulations were intended to ensure patient safety in the state’s ICUs, but new research led by physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) and published today in Critical Care Medicine found the staffing regulations were not associated with improved patient outcomes.

Released: 31-Aug-2018 9:45 AM EDT
Researchers Compare Chemotherapy Regimens for Best Outcomes in Invasive Bladder Cancer
Moffitt Cancer Center

Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Moffitt Cancer Center researchers examined data from more than 800 surgical patients with advanced bladder cancer.

Released: 31-Aug-2018 12:15 AM EDT
New Guideline Aids in Diagnosing Idiopathic Pulmonary Fibrosis
American Thoracic Society (ATS)

A new international guideline has been developed to help physicians diagnosis idiopathic pulmonary fibrosis (IPF), a rare and often fatal lung disease whose cause is unknown.

Released: 30-Aug-2018 10:05 PM EDT
NUS researchers use AI to successfully treat metastatic cancer patient
National University of Singapore (NUS)

A translational research team led by the National University of Singapore (NUS) has harnessed CURATE.AI, a powerful artificial intelligence (AI) platform, to successfully treat a patient with advanced cancer, completely halting disease progression. This new development represents a big step forward in personalised medicine.

   
28-Aug-2018 9:30 AM EDT
New Program Boosts Use of HIV Medications in Injection-Drug Users
Ohio State University

A relatively simple effort to provide counseling and connect injection-drug users with resources could prove powerful against the spread of HIV in a notoriously hard-to-reach population, new research suggests.

Released: 30-Aug-2018 4:00 PM EDT
Explainer: What is inflammation?
Van Andel Institute

Inflammation is the body’s reaction to a harmful stimulus, such as infection with a virus like the flu, an injury like a cut or scrape or chronic conditions such as Crohn’s disease. Although it is a normal and important part of our immune system’s defenses, when it sticks around too long it can be

Released: 30-Aug-2018 1:05 PM EDT
School of Medicine Researchers Receive $18 Million Grant to Study Connections between Heart Health and Cognition
Atrium Health Wake Forest Baptist

The National Institute on Aging, part of the National Institutes of Health (NIH), has awarded Wake Forest School of Medicine researchers a five-year grant worth more than $18 million to study the connections between heart health and brain health among participants in the Multi-Ethnic Study of Atherosclerosis (MESA).

Released: 30-Aug-2018 12:05 PM EDT
ACR Statement Regarding the Recent CMS Guidance on Indication-Based Formulary Design
American College of Rheumatology (ACR)

While we appreciate the agency’s efforts to make prescription medications more affordable, we have serious concerns about a new CMS guidance to allow Medicare Part D plan sponsors to implement indication-based formulary designs that allow plans to select drugs for their formularies based only on the disease indications they want to use.

Released: 30-Aug-2018 10:05 AM EDT
Selling Access to Human Specimens: Survey Reveals Public Attitudes
Michigan Medicine - University of Michigan

Universities that aim to raise money for research by selling access to their biobanks to private companies should tell patients, a new survey shows – and saying what the money will be used for will likely encourage patients to donate

27-Aug-2018 7:00 AM EDT
Cleveland Clinic-Led Trial Shows Unprecedented Slowing in Progressive Multiple Sclerosis
Cleveland Clinic

A promising drug slowed brain shrinkage in progressive multiple sclerosis (MS) by nearly half, according to new research led by Cleveland Clinic. Very limited therapies are currently available for this disabling form of the disease. The definitive results of the phase 2 trial – published in the New England Journal of Medicine – showed that the drug ibudilast decreased progression of brain atrophy in progressive MS patients by 48 percent versus placebo.

24-Aug-2018 3:05 PM EDT
Spinal Muscular Atrophy Drug May Be Effective If Started Later Than Previously Shown
American Academy of Neurology (AAN)

A drug shown to be effective in the treatment of babies with the rare muscle-wasting disease spinal muscular atrophy may be effective for muscle control even when treatment is started in children seven months and older, according to a study published in the August 29, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. Previous studies focused on children younger than seven months old.

27-Aug-2018 1:15 PM EDT
Scientists Take Big step Toward Finding Non-addictive Pain Killer
Atrium Health Wake Forest Baptist

With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.

Released: 29-Aug-2018 1:05 PM EDT
Access to 3D printing is changing the work in research labs
McMaster University

A group of McMaster researchers has designed and built specialized hardware for their research using an in-house 3D printer. The new lab instrument is capable of collecting massive amounts of data that will help these researchers in their quest to discover new antibiotics.

Released: 29-Aug-2018 12:05 PM EDT
New National Training Program Aims to Mainstream Glycosciences
UC San Diego Health

Over the next five years, the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, will award approximately $20 million to four academic centers to launch a new national Career Development Consortium for Excellence in Glycosciences.

Released: 29-Aug-2018 9:00 AM EDT
Single-Step Nasal Spray Naloxone Easiest to Deliver According to New Research
Binghamton University, State University of New York

Single-step nasal spray naloxone is the easiest to deliver, according to new research led by faculty at Binghamton University, State University at New York.

Released: 28-Aug-2018 11:05 AM EDT
Wolters Kluwer and the Family Physicians Inquiries Network Enter Publishing Partnership
Wolters Kluwer Health: Lippincott

Wolters Kluwer Health announced today it will begin electronic publishing of Evidence-Based Practice, the official journal of the Family Physicians Inquiries Network (FPIN). The monthly journal, which focuses on topics relevant to the daily practice of family medicine, will be curated in the Lippincott portfolio beginning in September 2018.



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