Pediatric Impact of COVID-19 and Other Respiratory Infections Clinical Prediction Tool for Prioritizing Respiratory Syncytial Virus Prevention Products for High-Risk Infants During Current Limited Availability of Nirsevimab in the United States
Patients with fibromyalgia and irritable bowel syndrome (IBS) who take multiple medications are more likely to develop severe drug intolerance than healthy patients, UT Southwestern Medical Center researchers reported. Their findings, published in The Journal of Allergy and Clinical Immunology: In Practice, could help health professionals prescribe drugs for patients and identify treatment plans for multiple drug intolerance syndrome (MDIS).
By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers. Their findings, reported in the Journal of Experimental Medicine, could lead to new treatments for these diseases that avoid the serious side effects of current therapies.
Over 150 researchers from across the University of Utah gathered to form new connections and share groundbreaking research on topics from antibiotic resistance to autoimmune diseases.
Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer immunotherapies.
A study led by Yale scientists, published April 25 in the journal Science Immunology, investigated the potential causes associated with T cell exclusion using a genome-wide screen of more than 1,000 human proteins.
The American Association of Immunologists (AAI) today announced its publishing partnership with Oxford University Press (OUP). OUP will publish the AAI journals, The Journal of Immunology (The JI) and ImmunoHorizons (IH), beginning in 2025.
Today the American Association of Immunologists (AAI), one of the world’s largest organizations of immunologists and scientists in related disciplines, is proud to announce the launch of its new brand identity.
Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.
A groundbreaking study has recognized the cGAS-STING signaling pathway as a formidable ally in the immune system's battle against cancer. This pivotal discovery may pave the way for innovative immunotherapies capable of amplifying the body's inherent defenses to detect and eradicate cancer cells, signifying a substantial advance towards more potent cancer treatments.
This method is a major leap forward for scientists investigating how proteins do their jobs in the immune system. “This method basically creates an entire new kind of world of experiments that people can do..."
Alexander Gow, Ph.D., professor and associate director of the Center for Molecular Medicine and Genetics and professor of pediatrics and neurology at the Wayne State University School of Medicine, received an award from the National Multiple Sclerosis Society for a study into the causes of multiple sclerosis.
The grant will explore the early roots of Multiple Sclerosis (MS) in patients that Gow believes may begin years — perhaps even decades — before symptoms become apparent.
Miriam Merad, MD, PhD, a world-renowned immunologist, has been appointed Dean for Translational Research and Therapeutic Innovation of the Icahn School of Medicine at Mount Sinai. The appointment reaffirms Icahn Mount Sinai’s commitment to pioneering medical progress and catalyzing the rapid advancement of research innovation. Dr. Merad, the Mount Sinai Professor in Cancer Immunology, will also continue to serve as the founding Chair of the Department of Immunology and Immunotherapy, Director of the Marc and Jennifer Lipschultz Precision Immunology Institute, and Director of the Human Immune Monitoring Center.
As Dean, Dr. Merad aims to elevate early clinical trials at Icahn Mount Sinai, streamline the clinical trial process, cultivate a culture of mechanistic clinical trials throughout the campus, and forge stronger partnerships with the pharmaceutical and biotech sectors.
May is Asthma and Allergy Awareness Month – the ideal time to get the word out on the different types of asthma, as well as the different triggers and treatments.
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Yale School of Medicine immunobiologist Akiko Iwasaki, PhD, will receive the 2024 Nakaakira Tsukahara Memorial Award from the Brain Science Foundation of Japan.
In the wake of the COVID-19 pandemic, many families worried about the long-term effects posed by the SARS-COV-2 virus. Now, researchers found that a SARS-COV-2 infection likely does not increase the risk of asthma development in pediatric patients. The findings were published today in the journal Pediatrics.
Wistar's Dr. Abdel-Mohsen has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.
A mutation in a protein regulating natural killer (NK) cells’ function is at the root of immune deficiency in some people with a rare genetic condition characterized by cognitive and developmental delay, seizures, and other manifestations. The findings also have broader implications for immunity and cell therapies.
The Federation of American Societies for Experimental Biology (FASEB) bestows its highest honor, FASEB Excellence in Science Awards, to three women scientists.
Researchers with McMaster University have crafted the first-ever guidelines to help prepare families who plan to build their child’s tolerance to common food allergens.
By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses. Their findings, reported in Nature Microbiology, could eventually lead to new ways to prevent or treat viral infections or thwart autoimmune diseases.
Wondering why some COVID-19 breakthrough cases feel milder than others? A groundbreaking study led by researchers at the Uniformed Services University (USU) sheds light on this phenomenon, offering insights into post-vaccination immunity dynamics.
Roundup of recent research involving UT Southwestern faculty members: Antibody treatment lowers risk for food allergies; Weight-loss surgery support offered for teens; Racial disparities found among pregnant patients with multiple sclerosis; Gestational age increased at start of COVID-19 pandemic
Researchers at the Keck School of Medicine, University of Southern California, have discovered that a protein called Piezo1 prevents a type of immune cell in the lung from becoming hyperactivated by allergens.
The American Association of Immunologists today announced the selection of Trainee Members as a Major Symposium speakers for the IMMUNOLOGY2024™ meeting – the premier immunology conference bringing together the best minds, sharing cutting-edge research, and providing opportunities to connect –to be held in Chicago May 3-7, 2024.
The American Association of Immunologists (AAI) is proud to announce the outcome of its recent elections, in which voting members of the association selected the officers and committee leaders who will guide the organization in the years ahead.
Infectious diseases specialists call the medical field to be ready to deal with the impact of climate change on spreading diseases, such as malaria, Valley fever, E-coli and Lyme disease.
Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.
Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine published a new study in the Journal of Infectious Diseases investigating the short-lived antibody response following SARS-CoV-2, the virus that causes COVID.
Researchers identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.
Researchers at the UNC School of Medicine have found that a metabolic enzyme called Acetyl-CoA Carboxylase causes T cells to store fat when they are in solid tumors, rather than burning fat for energy.
Nobel Laureate Brian Kobilka, MD, and NASA Astronaut Jessica Meir, PhD, are among the highlighted speakers who will attend the American Physiology Summit, the American Physiological Society’s (APS) flagship annual meeting.
“We are hoping to use this competition not just as a way to examine the capacity of people to predict vaccination outcomes, but also as a way to address an important public health question,” says Peters.
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Recognizing exceptional scientific contributions and noteworthy service to the American Association of Immunologists (AAI) and the wider immunology community, AAI announces its 2024 class of Distinguished Fellows.