After eight years of failed treatment for persistent atrial fibrillation (AF), Janet Szilagyi, 78 of Clayton, New Jersey, became the first patient in the United States to undergo cardiac ablation – a procedure in which an electrophysiologist will scar or destroy tissue in the heart that’s allowing incorrect electrical signals to cause an abnormal heart rhythm – using an intraoperative imaging and mapping system recently cleared by the Food and Drug Administration (FDA).
University of Illinois at Chicago researchers have discovered a way turn pluripotent stem cells into atrial cells. The discovery will enable them to better study atrial fibrillation, the most common heart rhythm disorder.
New research led by investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center suggests that the location of immune cells in the body determines whether they help or harm the development of heart disease. The study supports the view that the immune system directly impacts heart failure—still the leading cause of death for men and women in the United States.
The addition of a nurse-led intervention for hypertension management to health insurance coverage was more effective in lowering blood pressure (HPB) than the provision of health insurance alone in the Sub-Saharan country of Ghana, a region of Africa where HPB is rampant, according to a study publishing online on May 1 in the journal PLOS Medicine.
UCLA geneticists have created a technique to hunt for hormones that influence how organs and tissues communicate with each other. The method enabled them to find naturally occurring molecules that play major roles in Type 2 diabetes, obesity and cardiovascular disease.
Medicare and Medicaid beneficiaries with end-stage heart failure seeking OHT and LVAD implantation will be drastically affected if the proposed cuts are implemented, according to UAB research.
UT Southwestern cardiologist Dr. Ambarish Pandey has been named a Texas Health Resources Clinical Scholar. Funding from this award will bolster his studies developing novel approaches to prevent heart failure and improve heart failure outcomes at a health system level.
Scientists at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago have identified a gene called FoxM1 as a promising target for treatment of pulmonary hypertension, or high blood pressure in the lung arteries. Patients with this severe lung disease that damages the right side of the heart have a five-year survival rate of 50 percent. The study results, published in the American Journal of Respiratory and Critical Care Medicine, will drive development of new drugs to reverse a process called vascular remodeling, or thickening of lung artery walls – a key feature in pulmonary hypertension.
Mandatory public reporting of coronary artery bypass grafting (CABG) results in Massachusetts was associated with better patient outcomes compared to national findings, according to a recent study. Results of the 13-year Massachusetts experience were presented in a plenary session of the American Association for Thoracic Surgery’s 98th Annual Meeting.
PHILADELPHIA – Susan Brozena, MD, FACC, FAHA, an emeritus associate professor of Cardiovascular Medicine in the Perelman School of Medicine at the University of Pennsylvania, received the 2018 Lifetime Achievement Award from the American Heart Association. This award celebrates a professional who has had a pioneering career and has made an exceptional impact on their patients, the Philadelphia community and the field of cardiology.
A study by researchers from the National University of Singapore (NUS) and the University of Sao Paulo revealed that a beltway constructed to divert heavy-duty diesel vehicles traffic in the Brazilian city of Sao Paulo has reduced public health damage associated with exposure to diesel.
PHILADELPHIA – Two biostatisticians from the Center for Clinical Epidemiology and Biostatistics and professors of Biostatistics in Biostatistics and Epidemiology Mingyao Li, PhD, and Sharon Xie, PhD, have been elected fellows of the American Statistical Association, the largest professional organization for statisticians in the United States.
Doctors may do more good for diabetes patients by getting their cholesterol and blood pressure under control than by intensifying their glucose control.
Drinking kefir may have a positive effect on blood pressure by promoting communication between the gut and brain. Kefir is a fermented probiotic milk beverage known to help maintain the balance of beneficial bacteria in the digestive system. Researchers will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego.
Drinking kefir may have a positive effect on blood pressure by promoting communication between the gut and brain. Kefir is a fermented probiotic milk beverage known to help maintain the balance of beneficial bacteria in the digestive system. Researchers will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego.
Study of Mendelian randomization results detects factor called horizontal pleiotropy in close to 50 percent of significant causal relationships, a finding of great importance for detecting biomarkers for drug development and disease management
Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in mice, shedding light on the biology of this fatal disease.
According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub.
A major issue that limits modeling to predict cardiac arrhythmia is that it is impossible to measure and monitor all the variables that make our hearts tick, but researchers have now developed an algorithm that uses artificial intelligence to model the electrical excitations in heart muscle. Their work, appearing in Chaos, draws on partial differential equations describing excitable media and echo state networks to cross-predict variables about chaotic electrical wave propagations in cardiac tissue.
People who are 30 pounds or more overweight may want to slim down a bit even if they don’t have high blood pressure or any other heart disease risk, according to scientists at Wake Forest Baptist Medical Center.
Physicians from Cedars-Sinai and Stanford Children’s Health are teaming up to offer the newest treatments and surgical techniques to patients born with heart defects.
The new collaboration between the two prominent institutions features doctors from the Smidt Heart Institute’s Guerin Family Congenital Heart Program at Cedars-Sinai and the Betty Irene Moore Children’s Heart Center at Lucile Packard Children’s Hospital Stanford. Both teams focus on treating patients born with heart defects who require specialized care throughout their lives.
When compared with nondrinkers, men and women who had one or more alcoholic drinks per day had an overabundance of oral bacteria linked to gum disease, some cancers, and heart disease. By contrast, drinkers had fewer bacteria known to check the growth of other, harmful germs.
The bacteria that reside on and within our bodies are known to have a significant influence on our health. New research suggests wiping out the gut microbiota could improve heart functioning and potentially slow the cardiac damage that occurs with heart failure.
A team led by Columbia University Biomedical Engineering Professor Gordana Vunjak-Novakovic has designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts.
Media registration is now open online for TCT 2018 (Transcatheter Cardiovascular Therapeutics), the annual Scientific Symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine, attracting more than 10,000 attendees from 90 countries all over the world.
Scientists at The Scripps Research Institute have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate.
• Megan Gagliardi was diagnosed with dilated cardiomyopathy at 18 years old.
• Dilated cardiomyopathy is a condition in which the heart’s ability to pump blood is decreased because the left ventricle — the heart’s main pumping chamber — is enlarged and weakened.
• Gagliardi received a heart transplant on her 19th birthday and is doing well six years later.
Clinical trial planning is underway at MedStar Heart & Vascular Institute to determine whether a novel stem cell therapy will improve heart function for patients with heart failure.
People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers.
Steven Eaise was 47 years old when he was diagnosed with colon cancer in 2015. Today, a unique part of him lives on thanks to a music therapy project. Music therapists at UAB recorded Steven’s heartbeat, then incorporated it into a song, using his heartbeat in place of the drums. The Eaises were given a recording of the song after he passed away.
A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin).
A new substudy, published today in the Journal of the American College of Cardiology, analyzed outcomes in PRECISION based on the presence or absence of aspirin use with specific NSAIDs (nonsteroidal anti-inflammatory drugs).
Nathan Bryan, PH.D., one of the nation’s leading experts on the critically important role of nitric oxide in health and disease prevention will tell health care providers and the scientific community attending the Experimental Biology 2018 Conference,” Most, if not all of, chronic diseases are caused by decreased nitric oxide production. Regrettably we are a nation of low NO people. The impact of low NO will lead to increase disease and enormous cost.”
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation
A new paper published in Circulation by researchers at La Jolla Institute for Allergy and Immunology reports successful vaccination of atherosclerotic mice with a small chunk of protein snipped out of "bad cholesterol." Vaccination reduced plaque levels in test mice, and other experiments with human blood samples identified the class of T cells likely responsible for positive outcomes. The paper suggests that a comparable strategy could form the basis of a human vaccine.
As a sophomore and the star point guard of the Camas (Washington) High School Papermakers, it seemed Jake Hansel had a world of opportunities to play college ball. But all that changed for Hansel, now a Gonzaga University freshman studying mechanical engineering.
Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.
Select adult patients born with a single functioning ventricle (pumping chamber of the heart), and who have undergone a surgical operation called the ‘Fontan procedure’ during childhood, are now being enrolled in a global first clinical trial, led by a multi-disciplinary team of heart and lung physicians, to examine the effects of a portable, non-invasive medical device never before tested on patients with this cardiac condition.
Beta blockers have become a prescription drug staple for recovering heart attack patients. However, these blood pressure-reducing medications cannot be tolerated by many patients who are at higher risk for developing cardiovascular disease, including those with chronic obstructive pulmonary disease (COPD) and asthma, the elderly, and diabetics. As seen in the March 26 issue of Thyroid, researchers at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) now pose a new treatment for patients with beta blocker intolerance: thyroid hormone therapy.
More people are receiving coronary revascularization under Michigan's Medicaid expansion (the Healthy Michigan Plan). A new analysis finds that the expansion hasn’t caused significant problems for patients.
New leadless pacemakers are less invasive and cause fewer complications than standard pacemakers. A leadless pacemaker does not have wires or create a bulge under the skin. The size of a large vitamin pill, the device is deployed with a catheter and is secured to heart muscle inside the lower right pumping chamber.
UIC researchers have confirmed for the first time the association of a chromosomal genetic variant with increased risk of AFib in Latinos. Latino patients were found to be at a 2.3-fold increased risk for developing AFib if they carried this common genetic variant, which is labeled rs10033464 SNP at chromosome 4q25.