People who have received two or three doses of an mRNA COVID-19 vaccine are significantly more likely to have milder illnesses if infected with the Delta or Omicron coronavirus variants than those who are unvaccinated, according to a nationwide study involving a team of University of Utah researchers.
The GW School of Medicine and Health Sciences is recruiting participants for the final stage of a clinical trial to evaluate two Omicron-specific vaccines. The study, known as the COVID-19 Variant Immunologic Landscape (COVAIL) trial, is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). The George Washington University School of Medicine and Health Sciences has received funding support as an agreement under NIH contract number 75N91019D00024 to Leidos Biomedical Research in Frederick, Maryland.
The study of individuals from six countries finds that Europeans support transferring COVID-19 vaccines to poorer nations and prioritising those with the greatest need regardless of their country of residence.
The symptoms reported after administration of the Pfizer-BioNTech COVID-19 vaccine were comparable overall to those for approved non–SARS-CoV-2 vaccines in this study including 7,800 children younger than age 5.
A vaccine that could protect against new variants of SARS-CoV-2 and also potentially protect against other coronaviruses is one step closer to reality thanks to College of Medicine researchers.
FAU researchers and collaborators provide the most updated guidance to health care providers and urge how widespread vaccination with these boosters can now avoid the specter of future and more lethal variants becoming a reality.
Five experts from the Perelman School of Medicine at the University of Pennsylvania have been elected to the National Academy of Medicine (NAM), one of the nation’s highest honors in the fields of health and medicine. Regina Cunningham, Elizabeth Howell, Steven Joffe, Katalin Karikó, and Drew Weissman are among the 100 new members, elected by current NAM members.
New research published in the October 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network confirms the safety of mRNA vaccines in people with cancer undergoing immunotherapy treatment.
People with HIV who have moderate immune suppression appear to be at greater risk of severe COVID-19 “breakthrough” infection after vaccination, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
It’s that time of year: costumes, candy and trick-or-treating. As families celebrate this season, Johns Hopkins Children’s Center experts are available for interviews on a variety of tips to help ensure a safe and fun Halloween.
Rutgers New Jersey Medical School is one of nearly 80 sites in the United States that will enroll participants in a new study to evaluate whether tecovirimat is effective in treating human monkeypox.
People living with HIV must be included in clinical trials for new tuberculosis vaccine candidates currently in the development pipeline, say experts on an international panel convened last year to address gaps in the current TB vaccine landscape. Their recommendations appear in a new paper published today in The Lancet HIV.
Flu season is here. Rutgers Cancer Institute expert shares what cancer patients and their families need to know.
“Smart surveillance” for viral spillover from animals to humans, targeted preparedness & drug/vaccine research, & worldwide cooperation on stopping disease spread are required to reduce deaths & lessen economic consequences of the next pandemic, according to an international team of scientists.
University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer treatments. The genes control the immune system of the host, contributing to how fiercely the body responds to a COVID-19 infection.
A meta-analysis of 32 studies showed that the immune system within the vagina ebbs and flows, depending on menstrual-cycle stage. The analysis identified 53 distinct messages that immune cells sent to one another.
Referrals to Cambridge’s long COVID clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine.
One year after mass vaccination against COVID-19 was launched, inactivated virus vaccines accounted for half of the doses administered worldwide.
The coronavirus 2019 disease (COVID-19) pandemic has affected millions worldwide and claimed multiple lives. The elderly—aged above 60 years—remain the most vulnerable group.
The complex, multiple factors influencing COVID-19 vaccine hesitancy and scepticism among UK South Asian communities mean ‘quick fix’ solutions to increase uptake of the vaccines will be ineffective, according to new research published by JRSM Open.
An international team of researchers has demonstrated that among patients hospitalized for influenza, those who were vaccinated had less severe infections, including reducing the odds for children requiring admittance to an intensive care unit by almost half.
As COVID-19 wreaks havoc across the globe, one characteristic of the infection has not gone unnoticed. The disease is heterogeneous in nature with symptoms and severity of the condition spanning a wide range.
In a new study published online ahead of print in the journal Vaccine, Moffitt Cancer Center researchers identify factors associated with high and low COVID-19 vaccine acceptance among cancer patients.
The National Institutes of Health has awarded Amelia Escolano, Ph.D., assistant professor in The Wistar Institute’s Vaccine & Immunotherapy Center, the 2022 NIH Director’s New Innovator Award.
In one of the largest single-center COVID-19 cohort studies to date, researchers at the Icahn School of Medicine at Mount Sinai, using samples collected during the peak of the pandemic in New York City, have identified a key driver of COVID-19 disease severity.
In this population-based surveillance, the authors found that myocarditis/pericarditis 0 to 7 days after mRNA vaccination in persons aged 5 to 39 years occurred in approximately 1 in 200,000 doses after the first dose and 1 in 30,000 doses after second dose of the primary series, and 1 in 50,000 doses after the first booster. The incidence varied markedly by age and sex, however, with a disproportionate number of cases occurring in male persons, notably among adolescents after dose 2 and first boosters.
Rutgers Robert Wood Johnson Medical School’s Department of Pediatrics recently launched a website that presents multilingual resources about COVID-19 vaccines in children and young adults.
There is no evidence that the COVID-19 vaccination increases the incidence of Guillain-Barré syndrome, a rare neurological disorder in which the body’s immune system attacks the nerves, according to a Rutgers-led study.
Ochsner Health shares advice on the 2022 flu vaccine for kids
Scientists from the Nikol'skii Mathematical Institute of RUDN University built a mathematical model that describes the self-sustaining propagation of virus concentration waves – autowaves – in a tissue or cell culture, taking into account their competition for resources, that is the infected cells. The authors applied the constructed model to study variants of the new coronavirus, Delta and Omicron. It turned out that the autowave with the higher speed of spatial propagation wins, while the slow autowave dies. The studied processes relate to the competition and evolution of viral strains in the upper respiratory tract in vivo. In addition, the proposed approaches can be used when creating new methods for studying viruses in vitro.
In a study of more than 80 men and women from Baltimore, Maryland, Johns Hopkins researchers have added to evidence that COVID-19 booster shots are essential for maintaining long-term immunity against infection, particularly among older adults.
Evangelical Christians who sought information from their religious leaders about getting the COVID-19 vaccine were significantly less likely to be vaccinated, while evangelicals who spoke with a health care provider about the vaccine were more likely to be vaccinated, according to a new Virginia Commonwealth University-led study involving a survey of 531 self-identified evangelical Christians in the U.S.
Researchers from the University of California, Los Angeles (UCLA) have developed a Zika vaccine technology that is highly effective and safe in preclinical mouse models.
Amid the loosening of COVID-19 precautions and a sharp increase in flu cases in the Southern Hemisphere, Cedars-Sinai experts are warning the public to prepare for a bad flu season this year.
Texas already has a moderately high rate of flu cases in September. This doesn’t look good for flu season, which was uncharacteristically low last year because of masks and people isolating. Houston Methodist experts are encouraging the community to get the flu shot early. Experts say cases aren't usually seen this high until December, which is when the season usually peaks.
Since becoming available, vaccines against COVID-19 have been vital in preventing deaths.
Irvine, Calif., Sept. 26, 2022 – The University of California, Irvine has been awarded a five-year, $13.8 million contract from the National Institute of Allergy and Infectious Diseases to conduct detailed immune profiling of lipid nanoparticles to increase understanding of their role in enhancing vaccine protective responses and in causing side effects.
With the rollout of boosters of life-saving vaccines, new treatments, and a large population already infected, the U.S. is in a less vulnerable place than it was in 2020. However, the death toll, while lower than before, is still at around 400 deaths per day from COVID-19 in the U.S.
FINDINGS Women with COVID in pregnancy who are subsequently vaccinated after recovery, but prior to delivery, are more likely to pass antibodies on to the child than similarly infected but unvaccinated mothers are. Researchers who studied a mix of vaccinated and unvaccinated mothers found that 78% of their infants tested at birth had antibodies.
In the early stages of the COVID-19 pandemic, the coronavirus was everywhere – stuck to our cellphone screens, smeared on our mail, dangling from doorknobs, even clinging to our cereal boxes. Except that it wasn’t. Despite public health guidance suggesting surfaces be disinfected to stop the spread of COVID-19, the virus wasn’t significantly transmitted through inanimate surfaces and objects, what microbiologists call “fomites.” As with all respiratory viruses – from the flu to the common cold – transmission was and remains almost exclusively airborne. Emanuel Goldman, a professor of microbiology at the Rutgers New Jersey Medical School, was among the first scientists to challenge conventional wisdom by warning that hygiene theater – overzealous disinfection of surfaces – had “become counterproductive” for public health.
A Providence study released online today in the Journal of the American Medical Association sheds new light on the added benefit of a booster dose of a COVID-19 mRNA vaccine among previously vaccinated individuals.
Researchers from Northern Arizona University and the University of Washington School of Medicine in collaboration with the Washington National Primate Research Center received a five-year, $7.5 million grant from the National Institutes of Health to fund a groundbreaking project that they hope will result in a safe and effective vaccine for Valley Fever.
A recently discovered virus in a Russian bat that is similar to SARS-CoV-2, the virus behind COVID-19, is likely capable of infecting humans and, if it were to spillover, is resistant to current vaccines.
National Comprehensive Cancer Network Advisory Committee on COVID-19 Vaccination and Pre-exposure Prophylaxis details clarified expert consensus to help guide providers on latest data and information, available at NCCN.org/covid-19.
LJI research shows that a "slow delivery, escalating dose" vaccination strategy can prompt B cells to spend months mutating and evolving their pathogen-fighting antibodies.
Jasmin A. Tiro, PhD, MPH, has joined the University of Chicago Medicine Comprehensive Cancer Center as the new Associate Director of Cancer Prevention and Population Sciences. Tiro was formerly Professor of Population and Data Sciences at Harold C. Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center in Dallas.
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Though well-known as a respiratory illness, COVID-19 can also affect the nervous system. Now, researchers reporting in ACS Infectious Diseases have developed a new tool and possible vaccine candidate that could help scientists understand how SARS-CoV-2 could be invading these cells.
COVID-19 infection increases the risk of potentially life-threatening blood clots for at least 49 weeks, according to a new study of health records of 48 million unvaccinated adults from the first wave of the pandemic.
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