A basic science discovery by researchers at the Johns Hopkins Bloomberg School of Public Health reveals a fundamental way cells interpret signals from their environment and may eventually pave the way for potential new therapies.
UCLA has received seven grants totaling $6.4 million from the California Bureau of Cannabis Control. The awards will fund studies on topics ranging from the toxicity of inhaled and second-hand cannabis smoke to employment conditions in California’s cannabis industry.
By combing the ocean for antimicrobials, scientists at the University of Wisconsin–Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice.
Research may lead to identifying novel therapies for cardiac patients
Pairs of antibodies may be more effective than single antibodies at preventing and treating COVID-19, according to a new study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University in New York. The study, published November 19 in the Journal of Experimental Medicine (JEM), also suggests that in addition to blocking SARS-CoV-2’s entry into cells, the antibodies may combat the virus by enlisting various types of white blood cells to fight the infection.
Hertz Fellow Cheri Ackerman, Cofounder and CEO of Concerto Biosciences, has received the Hertz Foundation’s Harold Newman and David Galas Entrepreneurial Initiative Award. She plans to use the $25,000 grant to help her company find solutions for human health and agriculture using unique ensembles of microbes.
Texas Biomedical Research Institute (Texas Biomed) in San Antonio, Texas, was awarded $1 million from the Bill & Melinda Gates Foundation to test the efficacy of human monoclonal antibodies (MAbs) for the treatment of SARS-CoV-2 infection. MAbs are human-made proteins meant to mimic human immune system antibodies. Texas Biomed Professors Luis Martinez-Sobrido, Ph.D. and Jordi B. Torrelles, Ph.D. will co-lead the project to evaluate the protective efficacy of these MAbs in small rodent models, developed at Texas Biomed, on behalf of the Coronavirus Immunotherapy Consortium (CoVIC), an international nonprofit consortium evaluating MAb therapeutics for COVID-19.
Rutgers School of Public Health instructor, Stephanie Shiau, has been awarded a Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health R21 grant to examine the effect of HIV infection and/or exposure during pregnancy on epigenetic patterns in children.
While prostate cancer originates within the prostate, metastasis, or the spread of a tumor from the site of origin to other organs, remains a leading cause of death among people with the disease. Prostate tumors can metastasize to a number of different organs, including the liver, lymph nodes and bone.
Researchers at Washington University School of Medicine in St. Louis have identified a molecule that protects mice from brain infections caused by Venezuelan equine encephalitis virus (VEEV), a mosquito-borne virus notorious for causing fast-spreading, deadly outbreaks in Mexico, Central America and northern South America.
Experts trained a computer to tell which skin cancer patients may benefit from drugs that keep tumors from shutting down the immune system’s attack on them, a new study finds.
School of Medicine awarded $2.6M; receives two of 13 grants nationally
A new nationwide study of more than 50,000 individuals—coordinated by Columbia researchers—is now underway to determine factors that predict disease severity and long-term health impacts of COVID-19.
A new study from researchers at the University of Chicago has found that neuronal population dynamics in the motor cortex are very different during reaching and grasping behavior, challenging a popular theory that indicated intrinsic, dynamic patterns control motor behaviors.
The AMSSM Collaborative Research Network (CRN) is pleased to announce the recipients of the 2020 AMSSM CRN $300K Research Grant. Drs. Jonathan Drezner, Kimberly Harmon and Aaron Baggish will serve as co-principal investigators for their research project titled "Outcomes Registry for Cardiac Conditions in Athletes (the ORCCA Study): a Prospective, Multisite Research Study."
Shantanu Chakrabartty’s laboratory has been working to create sensors that can run on the least amount of energy. His lab has been so successful at building smaller and more efficient sensors, that they’ve run into a roadblock in the form of a fundamental law of physics.Sometimes, however, when you hit what appears to be an impenetrable roadblock, you just have to turn to quantum physics and tunnel through it.
Health care workers — particularly nurses — have a higher prevalence of SARS-CoV-2 infection than non-health care workers, according to researchers at Rutgers, which released baseline results from a large prospective study of participants at Rutgers and affiliated hospitals recruited during the early phase of the COVID-19 pandemic.
People who experience a crisis related to their behavioral health are often met by teams poorly equipped to respond to their disease, including police or emergency room teams. Now, Johns Hopkins Medicine and 14 other hospitals across Maryland have received $45 million in funding to start an initiative aimed at reducing unnecessary emergency department use and police interactions for substance use and mental health crises.
Children under age 2 who take antibiotics are at greater risk for childhood-onset asthma, respiratory allergies, eczema, celiac disease, obesity and attention deficit hyperactivity disorder, according to a paper written jointly by Mayo Clinic and Rutgers researchers. While previous studies have looked at the association of antibiotics with single diseases, this is the first to look at the association across many diseases.
The Department of Energy’s Oak Ridge National Laboratory and three partnering institutions have received $4.2 million over three years to apply artificial intelligence to the advancement of complex systems in which human decision making could be enhanced via technology.
A study from researchers at Washington University School of Medicine in St. Louis and St. Jude Children's Research Hospital in Memphis showed that, contrary to expectations, most people with severe COVID-19 do not suffer from unbridled inflammation. The findings suggest that anti-inflammatory therapies may not be helpful for most COVID-19 patients.
The Maryland state agency dedicated to containing the state’s health care costs has awarded Baltimore’s two academic medical centers $43 million over five years to take on the type 2 diabetes epidemic as part of a statewide population health initiative.
The bodies of people with uncontrolled diabetes appear to be the perfect environment for a common type of superbug to thrive unchecked and do its worst damage, according to new research by University of Pittsburgh School of Medicine scientists.
Researchers at the University of California San Diego have identified new mechanisms in neurons that cause Alzheimer’s disease. In particular, they discovered that changes in the structure of chromatin, the tightly coiled form of DNA, trigger neurons to lose their specialized function and revert to an earlier cell state. This results in the loss of synaptic connections, an effect associated with memory loss and dementia.
A team of scientists from Albert Einstein College of Medicine has received a five-year, $4.9 million grant from the National Institutes of Health (NIH) to establish a research center to investigate HIV- and human papillomavirus (HPV)-related cancers in Africa.
A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19.
The Connecticut Lions Eye Research Foundation has awarded a grant to Smilow Cancer Hospital at Yale New Haven and Yale Cancer Center.
The National Institute for Aviation Research (NIAR) has received another $13.7 million contract from the United States Air Force Research Laboratory (AFRL) to extend the Modeling for Affordable, Sustainable Composites (MASC) research program.
The United States may have set itself up for the spread of a pandemic without even knowing it.According to new research from the McKelvey School of Engineering at Washington University in St. Louis, pollution may bear part of the blame for the rapid proliferation in the United States of SARS-CoV-2, the virus responsible for the spread of COVID-19.
DALLAS – Nov. 12, 2020 – UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.
An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.
A collaboration to accelerate research to cure type 1 diabetes and improve lives.
Plastomics Inc., an agricultural biotech start-up developing the next generation of trait delivery technology, has been awarded a competitive grant from the United Soybean Board (USB) to develop disease resistant soybeans.
Military and law-enforcement personnel repeatedly exposed to low-level blasts have significant brain changes – including an increased level of brain injury and inflammation – compared with a control group, a new study has found.
Scientists at Sanford Burnham Prebys Medical Discovery Institute, University of California San Diego School of Medicine and Hopp Children’s Cancer Center Heidelberg (KiTZ) have demonstrated that personalized drug screens can be used to identify new therapeutic candidates for medulloblastoma. The approach measures the effectiveness of therapeutics using tumor cells obtained from a biopsy and can be performed in a few days—making it one of the quickest sources of information used in clinical decision-making.
The study showed that health insurance expansions increased early-stage cancer diagnoses, while rates of late-stage cancer decreased.
Researchers have discovered a previously undescribed set of neurons called saccade-vergence burst neurons that help control our eyes as they view in three-dimensional space. Models had predicted the existence of such neurons, which are in the mid-brain’s central mesencephalic reticular formation.
While quick-acting inhalers and medications can reduce inflammation during an asthma attack, people with asthma have few tools to prevent the next attack from coming. Now researchers at La Jolla Institute for Immunology (LJI) have discovered that blocking two immune molecules at the same time is key to preventing asthma attacks in a mouse model.
Researchers at Rutgers University, the Copenhagen Prospective Studies on Asthma in Childhood and the University of Copenhagen have described for the first time how delivery by caesarean section interferes with a baby’s ability to obtain beneficial germs from the mother’s microbiome, and how this can lead to early childhood asthma.
Researchers from the Pittsburgh Center for Pain Research uncovered additional complexities behind mechanical allodynia – the sensation of pain from innocuous stimuli, such as light touch.
Thomas S. Valley, MD, of the University of Michigan has been selected as the first-ever recipient of the ATS/CHEST Foundation Research Grant in Diversity. The focus of the research grant is clinical research that contributes to the understanding of the pathophysiology of treatment of conditions related to pulmonary, critical care, or sleep medicine that disproportionately affects underrepresented minority patient groups.
Peter Jackson, MD, of Virginia Commonwealth University, has been named the first recipient of the CHEST Foundation/ATS Research Grant in COVID and Diversity.
Intellia Therapeutics Receives Grant to Develop Curative CRISPR/Cas9 In Vivo Sickle Cell Disease Treatments
The SilverLining Safe Climate Research Initiative has awarded a $500,000 grant to a Cornell University engineering researcher, who will model the effects of introducing reflective aerosols into the stratosphere, which could deflect enough sunbeams to reduce Earth’s temperature and limit climate change impact.
The Michigan Translational Research and Commercialization (MTRAC) Innovation Hub for Advanced Computing at Wayne State University recently awarded a combined $270,000 in funding to three transformative innovation research projects led by Wayne State researchers. These projects aim to tackle deep technology opportunities in high impact sectors, such as artificial intelligence (AI)/machine learning, augmented reality (AR) and intelligent automation.
A team of researchers from Michigan State University, University of Michigan and tech-training company SIMmersion received a $3 million grant from the National Institute of Mental Health to develop a virtual reality training tool for youth with autism spectrum disorder, or ASD, to improve their social skills as they transition from high school to the workforce.
Michigan Tech physicist Issei Nakamura has received a National Science Foundation (NSF) CAREER Award for his research on computational methods to simulate how polymeric liquids interact with electric charges.
The University of Arkansas at Little Rock is part of a coalition of universities and industry partners that are developing a curriculum to increase cybersecurity talent focused on health care with $6.3 million in funding from the National Security Agency. UA Little Rock will work with the University of Louisville, the University of North Florida, Bluegrass Technical and Owensboro Technical, the Forge Institute, and a coalition of industry partners to develop a training curriculum focused on health care cybersecurity.
According to the National Institute of Mental Health (NIMH), in 2017 approximately 13% of adolescents in the United States, or 3.2 million children aged 12 to 17, had at least one major episode of depression. While many recover from such an episode, a significant portion will develop severe depression or a chronic mood disorder. There is an urgent need to identify adolescents who are at higher risk for serious problems and may benefit from aggressive treatment.
An artificial intelligence technique — machine learning — is helping accelerate the development of highly tunable materials known as metal-organic frameworks (MOFs) that have important applications in chemical separations, adsorption, catalysis, and sensing.
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