Attention has focused on how NSAIDs may cause dysfunction of the immune system. Researchers now have found that sub-acute pretreatment with the NSAID carprofen before experimental heart attack in mice impaired resolution of acute inflammation following cardiac injury.
Diabetics are at least twice as likely as nondiabetics to die of heart disease. They’re also at a greater risk of heart attack. With a two-year, $53,000 fellowship from the American Heart Association, Quincy Hathaway, a doctoral candidate in the West Virginia University School of Medicine, is examining how a certain protein, called PNPase, influences mitochondria’s performance in heart cells.
MyoKardia, a clinical-stage biopharmaceutical company pioneering precision medicine for the treatment of cardiovascular diseases, today announced the launch of the MyoSeeds™ Research Grants Program, a new initiative to support original, independent research in the biology and underlying mechanisms of cardiomyopathies and precision heart disease treatment with the goal of improving the lives of patients.
In a remarkable new genetic discovery, researchers at the Peter Munk Cardiac Centre, University Health Network (UHN), Ted Rogers Centre for Heart Research and The Hospital for Sick Children (SickKids) have found strong evidence that rare DNA variations can lead to Tetralogy of Fallot (ToF).
Separated entry and exit doors for calcium keep energy production smooth in the powerhouses of heart cells.
Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. More than 200 million people worldwide suffer from the condition.
A new study finds that patients who underwent TAVR had a significantly shorter length of stay and were significantly less likely to be transferred to a skilling nursing facility compared to patients who underwent SAVR.
A new wearable ultrasound patch that non-invasively monitors blood pressure in arteries deep beneath the skin could help people detect cardiovascular problems earlier on and with greater precision. In tests, the patch performed as well as some clinical methods to measure blood pressure. Applications include real-time, continuous monitoring of blood pressure changes in patients with heart or lung disease, as well as patients who are critically ill or undergoing surgery.
A new $3 million, five-year grant from the National Heart, Lung and Blood Institute will allow researchers to determine whether a unique program designed to educate people with uncontrolled hypertension — also known as high blood pressure — about the importance of getting their blood pressure under control can help reduce the risk of developing chronic and expensive-to-treat secondary cardiovascular conditions among this high-risk group.
In a proof of concept study, scientists at Johns Hopkins report they have successfully performed 3D personalized virtual simulations of the heart to accurately identify where cardiac specialists should electrically destroy cardiac tissue to stop potentially fatal irregular and rapid heartbeats in patients with scarring in the heart. The retrospective analysis of 21 patients and prospective study of five patients with ventricular tachycardia, the researchers say, demonstrate that 3D simulation-guided procedures are worthy of expanded clinical trials.
Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. When combined with a nuclear DNA mutation in mice, one mitochondrial variant made heart disease worse, while another variant conferred protection.
The University of Chicago Medicine and Almoosa Specialist Hospital, a private hospital in the Al-Ahsa region of Saudi Arabia offering comprehensive medical care, have signed a collaboration agreement.
Epidemiological studies have established a strong correlation between inhaling ultrafine particles from incomplete combustion and respiratory and cardiovascular diseases. Still, relatively little is known about the mechanisms behind how air particulates affect human health. New work with carbon nanodots seeks to provide the first model of how ultrafine carbon-based particles interact with the lung tissues. Researchers created a 3D lung cell model system to investigate how carbon-based combustion byproducts behave as they interact with human epithelial tissue. They discuss their work in Biointerphases.
In mouse experiments, scientists have shown a way to hit an immunological “reset button” that ends inappropriately sustained inflammation. This reset reverses the pathologic enlargement and pumping failure of the heart, and it suggests a therapeutic approach to treating human heart failure.
The Hypertrophic Cardiomyopathy Program at the University of Maryland Heart & Vascular Center (UMHVC) has been recognized as a Center of Excellence by the Hypertrophic Cardiomyopathy Association (HCMA) – one of about 30 Centers of Excellence nationwide and the only HCMA-recognized center in Maryland.
In addition to reducing overall heart failure by 25 percent, increased physical activity benefited two heart failure subtypes defined by cardiac function: reduced ejection fraction, which typically has a worse prognosis, and preserved ejection fraction, which is more common in older adults, especially women and racial-ethnic minorities.
A study led by researchers at the Peter Munk Cardiac Centre (PMCC) at UHN suggests that the model used by the Canadian Institute for Health Information (CIHI) significantly underestimates mortality in specialized heart surgery centres. The findings show that CIHI's model does not capture all of the medical problems that patients at high risk for surgery have.
The Cardiovascular Research Foundation (CRF) has announced the press conference schedule for late-breaking trials and late-breaking clinical science that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2018 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place September 21-25 in San Diego, California.
Having atrial fibrillation (AFib) can increase your risk for stroke and heart failure. It’s vital to know your risk and get help before it strikes.
Craig A. Thompson, MD, MMSc , whose seminal, pioneering achievements are now a standard of care for re-vascularization of totally blocked coronary arteries, has been named director of cardiac catheterization laboratories at NYU Langone Health System .
Professor of Psychology Melinda Green is greatly expanding her research on eating disorders with the notification that she’s been awarded a grant for nearly $400,000 from the National Institute of Mental Health.
The latest research, features and announcements in healthcare in the Healthcare News Source
The National Institute on Aging, part of the National Institutes of Health (NIH), has awarded Wake Forest School of Medicine researchers a five-year grant worth more than $18 million to study the connections between heart health and brain health among participants in the Multi-Ethnic Study of Atherosclerosis (MESA).
Biomedical Engineering Professor Rita Alevriadou has spent most of her career, which spans two decades, on cardiovascular disease. Her current research on the effects of blood flow on our artery walls recently earned a $1.8 million grant from the National Institutes of Health (NIH).
Heart attack patients given a different type of breathing tube by paramedics had better survival rates than those treated by traditional intubation breathing tube methods – findings that could potentially save more than 10,000 lives annually, researchers report.
Results of a clinical trial led by MedStar Heart & Vascular Institute using transcatheter aortic valve replacement provided a “strong signal” that it is safe for patients with low surgical risk, potentially helping to open the way for broader use of the minimally invasive procedure, also known as TAVR.
Over the next five years, the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, will award approximately $20 million to four academic centers to launch a new national Career Development Consortium for Excellence in Glycosciences.
The novel program in Advanced Congenital Cardiac Therapies (ACCT) allows for patients to be evaluated for heart transplantations and ventricular assist devices (VAD).
Middle-aged and older women who exercise moderately to vigorously, three times a week for at least 30 minutes, were able to significantly reduce cardiac risk factors in just six months.
Now scientists of the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences are using research from several large global studies to develop an updated, international approach of identifying a healthy diet.
A study comparing two breathing tubes used by paramedics during out-of-hospital cardiac arrest shows that the King laryngeal tube was superior to the more commonly used endotracheal tube, according to findings of the Pragmatic Airway Resuscitation Trial.
Munich, Germany: Researchers at Cleveland Clinic, University of Oxford and University of Erlangen have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries.
A study led by Columbia University cardiologist Mathew Maurer showed that tafamidis reduces deaths from a type of heart failure called transthyretin amyloid cardiomyopathy. The drug could be one of the first effective treatments for the disease.
Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart — a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.
Patients with cardiovascular disease who develop major internal bleeding are much more likely to be diagnosed with cancer, a large international clinical trial has found. Patients with gastrointestinal (GI) bleeding are 18 times more likely to be diagnosed with GI tract cancer, and those who major genitourinary (GU) tract bleeding are 80-fold more likely to be diagnosed with GU cancer, than patients without internal GI or GU bleeding, respectively.
Study by Rutgers Physician Finds Medicaid Eligibility Expansion May Have Contributed to Decrease
States that expanded eligibility for their Medicaid program in 2014 when the Affordable Care Act (ACA) was implemented, saw fewer uninsured patients among major cardiac-related hospitalizations in the first year compared with states that did not expand the program.
A leading cardiologist at Beth Israel Deaconess Medical Center shares what he eats for breakfast
Columbia researchers developed a UVC light-diffusing system to sterilize skin-penetrating medical devices. The system could prevent infections in people with these devices.
People are falling into a trap of greater inactivity during middle age, according to new research from The University of Texas Health Science Center at Houston (UTHealth), which calls for its findings to be considered in future national physical activity guidelines.
Individual variations in genetic makeup and gut bacteria may explain the different effects of antibiotics on blood pressure, a new rat study suggests. The findings are published ahead of print in Physiological Genomics.
Albeir Mousa, a professor of vascular surgery at West Virginia University, has used an innovative, faster method for ruling out DVT in patients before they have an ultrasound. He and his research team found that measuring the level of a specific protein—called D-dimer—in a patient’s blood may predict whether a time-intensive ultrasound is warranted. The “Annals of Vascular Surgery” has published the team’s results.
As part of a new study, researchers at the University of Notre Dame aim to create a more optimal computer network for solving complex problems — using heart cells.
The hearts of newborn piglets can almost completely heal themselves after experimental heart attacks, the first time this ability to regrow heart muscle has been shown in large mammals. This regenerative capacity disappears by day three after birth, researchers report in the journal Circulation.
Seattle Children’s today announced the opening of its newest regional clinic, Seattle Children’s North Clinic, which will provide convenient access to pediatric specialty care services for families in north King, Snohomish, Whatcom and Skagit counties. The 37,000-square-foot clinic is located on Providence Regional Medical Center Everett’s Colby Campus at 1815 13th St.
Researchers at the University of California San Diego School of Medicine report that women whose mothers lived to at least age 90 were more likely to also live to 90, free of serious diseases and disabilities.
Tulane University research could shed light on the molecular details of Alzheimer’s and Parkinson’s.
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