Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.
A team of Dartmouth investigators have engineered therapeutic cells encapsulated in nanoporous capsules to secrete antitumor molecules from within the tumor.
The most detailed study to date showing how electrical stimulation accelerates wound healing has been carried out in 40 volunteers by University of Manchester scientists.
"Innovations in Neuromodulation," a preconference of the International Neuromodulation Society 12th World Congress, presents updates and opinions from representatives of early–stage companies and venture capitalists to approximately 200 investors, entrepreneurs, device company executives, and medical professionals.
Trending news releases with the most views in a single day. Topics include: tick-borne disease, 3D printing, childhood cancer and obesity, nursing, low-back pain, brain cells, and fluid dynamics.
Trending news releases with the most views in a single day. Topics include: vision research, DOE research, aging, mental health, children's health, cancer, tick-borne disease, and drone technology.
Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite. This discovery opens up a promising new avenue for the development of therapies to treat and prevent malaria.
Trending news releases with the most views in a single day. Topics include: WWII and PTSD, stem cells, cancer, racial segregation, supplements and glaucoma, medical research, cybersecurity, vision research, and physics.
The Global Biological Standards Institute (GBSI) has launched a video competition as part of its #authenticate campaign, which is designed to raise awareness in the life science community about the powerful role cell authentication can play in improving research reproducibility and fidelity.
Trending news releases with the most views in a single day. Topics include: new biotech treatment for radiation proctitis, 3D printing in children's health, work and brain health, the importance of medical research, multi-institute collaboration on medical education technology, tax cuts and the economy, cancer survival, and Alzheimer's research.
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Trending news releases with the most views in a single day. Topics include: Underage drinking, dieting, electrical engineering, neurology and genetics, Nepal earthquake, breast cancer, and supercomputing.
Herceptin has been touted as a wonder drug for women with HER2-positive breast cancer, an aggressive form of the disease that is fueled by excess production of the HER2 protein. However, not all of these patients respond to the drug, and many who do respond eventually acquire resistance.
Trending news releases with the most views in a single day. Topics include: exercise and obesity, Focused Ultrasound to treat uterine fibroids, neurology, diet supplements and cancer (day 4 in top 10), genetics, geology, skin cancer, sleep and Alzheimer's, and water conservation.
Trending news releases with the most views in a single day. Topics include: diet supplements and cancer, pancreatic cancer, bird flu, parenting, respiratory health, physics from the DOE office of science, breast cancer awareness, and childhood cancer survivors.
University at Buffalo researchers have discovered a way to easily and effectively fasten proteins to nanoparticles – essentially an arranged marriage – by simply mixing them together. The biotechnology, described April 20 online in the journal Nature Chemistry, is in its infancy. But it already has shown promise for developing an HIV vaccine and as a way to target cancer cells.
Trending news releases with the most views in a single day. Topics include:sustainability, COPD, neurology, cancer, sleep, food, and genetics.
Trending news releases with the most views in a single day. Topics include: robotics, nicotine and alcohol, stem cells, vision, cancer, pregnancy, racial disparities in smoking risk, and herbal therapy for cardiac hypertrophy
New paper in the journal, Molecular Therapy – Methods & Clinical Development, describes how Melligen cell lines coupled with a live cell encapsulation technology such as Cell-in-a-Box® can reverse Type I Diabetes per a team at the University of Technology Sydney and the University of Sydney in Australia.
By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.
CENTOGENE AG (“CENTOGENE”) announces the launch of the world’s largest genetic mutation database for rare diseases, CentoMD®.
In a new study, researchers report progress toward perfecting a radical new method of producing vaccines using genetically modified corn. The approach could lead to an oral hepatitis B vaccine that requires no refrigeration and costs less than $1 per dose to manufacture.
Findings Shed Light on the Development of Blood Cancers
New research from an Iowa State University economist found consumers were willing to spend more for biotech potato products with reduced levels of a chemical compound linked to cancer.
University of Washington researchers have developed a new injectable polymer that strengthens blood clots, called PolySTAT. Administered in a simple shot, the polymer finds unseen injuries and has the potential to keep trauma patients from bleeding to death before reaching medical care.
A plastic used in filters and tubing has an unusual trait: It can produce electricity when pulled or pressed. This ability has been used in small ways, but now researchers are coaxing fibers of it to make even more electricity for a wider range of applications from green energy to “artificial muscles.” They will report progress on a novel form of this plastic at the 249th National Meeting & Exposition of the American Chemical Society.
Water-borne algal blooms from farm fertilizer runoff can destroy aquatic life and clog rivers and lakes, but scientists will report today that they are working on a way to clean up these environmental scourges and turn them into useful products. The algae could serve as a feedstock for biofuels, and the feedstock leftovers could be recycled back into farm soil nutrients.
Squid are the ultimate camouflage artists, blending almost flawlessly with their backgrounds so that unsuspecting prey can’t detect them. Using a protein that’s key to this process, scientists have designed “invisibility stickers” that could one day help soldiers disguise themselves, even when sought by enemies with tough-to-fool infrared cameras.
Biocompatible and biodegradable, cellulose materials are being studied for use in high-performance composites and optical films, and to deliver medicine in pills. But before a material can be commercialized, its impact on human health must be determined.
Researchers at the Stowers Institute for Medical Research have developed a high-resolution method that can precisely and reliably map individual transcription factor binding sites in the genome, vastly outperforming standard techniques
Nanometer-sized “drones” that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis.
Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite. The method is the newest attempt to develop a vaccine that prevents transmission of the malaria parasite from host to mosquito.
While methods for identifying immunogenic hotspots, or epitopes, are evolving rapidly, technologies to redesign the hotspots while maintaining biotherapeutic activity and stability are far less developed.
NIBIB-funded researchers have developed a novel 3D vaccine that could provide a more effective way to harness the immune system to fight cancer as well as infectious diseases. The vaccine spontaneously assembles into a scaffold once injected under the skin and is capable of recruiting, housing, and manipulating immune cells to generate a powerful immune response. The vaccine was recently found to be effective in delaying tumor growth in mice.
To help people with hormone deficiencies, scientists at The Scripps Research Institute have developed a potential new therapy based on an unlikely model: immune molecules from cows. Their research shows that human hormones and antibodies can be fused together—mimicking long, stalk-like cow antibodies.
Scientists will examine living cells at a molecular level to find out how cells become cancerous, how viruses attack animals and humans and how plants can capture more nitrogen through a new collaborative research center called Biochemical Spatio-temporal NeTwork Resource (BioSNTR). The center brings together South Dakota plant and animal scientists, biochemists and biomedical engineers to improve human health and agriculture as part of the state’s science and technology plan.
Researchers identify signaling molecules in intestinal stem cells that can lead to tumors if left unregulated. The findings suggest a new approach to targeting intestinal cancers.
To prepare for people for safely journeying into space for extended periods of time in the future, it's crucial to gain a better understanding of the biophysics involved within reduced gravity and microgravity environments. To this end, a team of University of Delaware researchers is preparing to send transparent microscopic worms called "Caenorhabditas elegans" up to the International Space Station.
Richard Kim, MD, a cardiac surgeon at Children’s Hospital Los Angeles, recently used a 3D printed heart as a model to plan a life-saving procedure for his young patient, Esther Perez.
People’s perceptions of the cost of a drug may affect how much they benefit from the drug, even when they are receiving only a placebo, according to a new study of people with Parkinson’s disease published in the January 28, 2015 online issue of Neurology®, the medical journal of the American Academy of Neurology.
By establishing protein design algorithms that simultaneously optimize drug candidates for both decreased immunogenic epitope content and high level stability and activity, researchers have established a novel testing platform.
A team of oncology and genetic researchers from Georgetown Lombardi and electrical and computer engineers and bioinformatics specialists from Virginia Tech collaborated in an effort designed to study the living cell as an information processing system.
An international team of researchers says climate change, the loss of biosphere integrity, land-system change, and altered biogeochemical cycles like phosphorus and nitrogen runoff have all passed beyond levels that put humanity in a “safe operating space.” Civilization has crossed four of nine so-called planetary boundaries as the result of human activity, according to a report published today in Science by the 18-member research team.
A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice.
In a new study researchers at the UCLA Jonsson Comprehensive Cancer Center have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage.
While considered a delicacy in some parts of the world, snails have found a more intriguing use to scientists and the medical profession offering a plethora of research possibilities.
Innovative scoring system uses “Ann Arbor GVHD score” to better predict how patients will respond, minimize side effects
Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to researchers at Washington University School of Medicine in St. Louis.
UCLA researchers have for the first time developed a method that defines many stages of reprogramming skin or blood cells into pluripotent stem cells. Study analyzed the reprogramming process at the single-cell level on a daily basis. Results determined that stages of cell change were the same across different reprogramming systems and cell types analyzed.
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