After a spinal cord injury, a significant amount of secondary nerve damage is caused by inflammation and internal scarring that inhibits the ability of the nervous system to repair itself.
Balancing school and sleep; Researchers report link between cells associated with aging and bone loss; Discovery of new prostate cancer biomarkers could improve precision therapy...
Scientists at Children’s Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease. HME causes multiple, disabling bone outgrowths (called exostoses or osteochondromas) and skeletal deformities, and such drugs could potentially spare patients the prospect of numerous, sometimes difficult childhood surgeries, while also reducing their risk of cancer.
More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting.
Doctors believe there is some good to be found in nicotine, the highly addictive drug in tobacco products. Lung experts at The Ohio State University Wexner Medical Center are testing whether nicotine can help people with a chronic inflammatory lung disease called sarcoidosis.
An exploration of the latest understanding of the complex mechanisms behind OA pain offers new possibilities and potential treatment targets for osteoarthritis (OA) pain. New areas of research discussed include the use of combination therapies and the development of biomarkers to target effective pain treatment.
“Expanding our patients’ access to safe, effective, and affordable biologic and biosimilar therapies is a top priority of the rheumatology community. Therefore, the American College of Rheumatology applauds new legislative and regulatory developments that will expedite the approval of new therapies, increase competition, and lower the cost of these drugs.
A study led by a biomedical researcher at Iowa State University found that a potential treatment for spinal muscular atrophy, a leading genetic cause of infant mortality, shows promise in animal models.
A study lead by Northern Arizona University bioengineer Zach Lerner found that wearing a robotic exoskeleton—a leg brace powered by small motors—could alleviate crouch gait in children with cerebral palsy.
Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae. When chemically modified, this "alginate" reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis. The research is, however, still in its infancy.
After-school activities like sports, clubs, dance lessons and volunteering provide important enrichment opportunities for schoolchildren, but too much participation without enough downtime, or participating for the wrong reasons could lead to unhealthy levels of stress in children.
Mayo Clinic researchers have reported a causal link between senescent cells – the cells associated with aging and age-related disease – and bone loss in mice. Targeting these cells led to an increase in bone mass and strength. The findings appear online in Nature Medicine.
Early surgery to repair tears of one of the shoulder rotator cuff muscles provides lasting improvement in strength, function, and other outcomes, reports a study in the August 16, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
Hospital for Special Surgery is giving new meaning to the term "patient care." The hospital took patients with cerebral palsy and other physical conditions on an adaptive surfing trip on Long Island.
The University of New Mexico Comprehensive Cancer Center began helping New Mexicans with blood disorders a little more than one year ago. It is the state’s only bone marrow transplant program. The program offers treatment choices for people with lymphoma and myeloma and will expand to help people with other blood disorders.
A neck condition called cervical myelopathy, which compresses the spinal cord, was severely limiting Kenneth Caudle's activity as both a firefighter and a family man. After a spinal fusion surgery in his neck, Mr. Caudle has returned to a full range of activities at the fire station and at home.
A short exposure to an alternating magnetic field might someday replace multiple surgeries and weeks of IV antibiotics as treatment for stubborn infections on artificial joints, new research suggests.
In addition to refining treatment recommendations and reorganizing information to be presented in a more user-friendly format, the team expanded the guidelines, last updated in 2008, to include information on screening, evaluation, diagnosis and treatment–based classifications. The guidelines are used by physical therapists in clinical settings, insurers/payers, policy-makers, graduate students and educators.
The XIVth International Congress of Paediatric Laboratory Medicine (ICPLM) and the Task Force on Paediatric Laboratory Medicine (TF-PLM) of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), invite you to the Congress in Durban, South Africa on October 20-22nd 2017.
Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages. Its aggressiveness, rarity and diversity continue to hinder efforts to identify effective therapies for people with this malignancy. Patient-derived orthotopic xenografts (PDOX) are unique models where a patient’s individual tumor is grown in mice. Such xenografts have long shown great promise in modeling how sarcoma and other cancers can respond to and resist therapies, but their feasibility for use in individual patients in clinical settings remains unknown.
A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16. In a recent study, researchers showed that allowing surgeons to prep on a 3D-printed model of the patient’s hip joint cut by about 25 percent the amount of time needed for surgery when compared to a control group.
A new study published in the HSS Journal by HSS anesthesiologist Michael K. Urban, MD, PhD, sheds light on reducing cardiac complications in orthopedic surgery.
Bone fracture risk due to weightlessness is a significant challenge for future space missions. Here on earth, individuals who cannot bear weight on a limb or limbs due to injury, aging or disease, risk bone deterioration that can impact their quality of life.
The American Chiropractic Association (ACA) and chiropractors nationwide will observe National Chiropractic Health Month (NCHM) this October by sharing information on back pain prevention and the value of a conservative approach to treatment with the theme “Back to Basics.”
3.6 out of 1000 children in the U.S. are diagnosed with cerebral palsy. Their symptoms can include abnormal gait patterns such as crouch gait, characterized by excessive flexion of the hips, knees, or ankles. A pilot study led by Columbia Engineering’s Sunil Agrawal was published today in Science Robotics that demonstrates a robotic training method that improves posture and walking in children with crouch gait by enhancing their muscle strength and coordination.
A new study led by researchers at University Hospitals Coventry and Warwickshire (UHCW) NHS Trust and the University of Warwick has recommended an alternative method of pain relief for patients undergoing knee replacement surgery.
Wolters Kluwer, a leading global provider of information and point of care solutions for the healthcare industry, announces the release of Postoperative Orthopaedic Rehabilitation, a new book published in partnership with the American Academy of Orthopaedic Surgeons (AAOS) that serves as a go-to reference for anyone involved with orthopaedic surgery and the resulting rehabilitation. Edited by Dr. Andrew Green, Dr. Roman Hayda, and Dr. Andrew C. Hecht, Postoperative Orthopaedic Rehabilitation covers rehabilitation protocol for orthopaedic procedures and provides readers with a deeper understanding of patient management in each phase of treatment.
For patients undergoing surgery to repair a bunion deformity of the foot, non-weight-bearing x rays taken immediately after surgery can provide a good estimate of the risk that the bunion will return over time, reports a study in the current issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
A professor at the University of Birmingham has been appointed to a key role focusing on developing research to improve treatment and outcomes for patients with arthritis.
Better education to coaches and parents about the effects of single sport specialization is critical, say researchers presenting their work today at the American Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Canada.
The arthroscopic superior capsule reconstruction (SCR) surgical technique can offer patients with irreparable rotator cuff repairs the opportunity to return to sports and jobs that require heavy physical work, as presented in research today at the American Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada.
Pain medicine specialists at Rush have helped develop, and are among the first in the country to provide, a noninvasive treatment for knee arthritis that uses cooled radio energy to target and interrupt pain signals. Known as “Coolief,” the procedure can provide several months of relief from chronic arthritis pain for patients for whom surgery is not an option.
Young patients who suffer patellar dislocations are at a higher risk of recurring dislocations, especially long-term after their initial injury, according to research presented today at the American Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada. Researchers received the Herodicus Award, presented to the best resident paper featured at the meeting, and determined by the Herodicus Society.
Increasing numbers of elbow-related injuries in professional baseball pitchers has led to research studying risk factors, especially those that can be modified and adjusted to help prevent lost playing time. Decreased shoulder flexion and external rotation were identified as key predictors of injuries to pitchers during the season, according to a study presented today at the American Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada.
Surgery is an effective and safe option to treat patients with pectoralis major tendon (PMT) ruptures, generally demonstrating a low risk of re-rupture and complications, according to research presented today at the American Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada.
Whey protein supplements aren’t just for gym buffs according to new research from McMaster University. When taken on a regular basis, a combination of these and other ingredients in a ready-to-drink formula have been found to greatly improve the physical strength of a growing cohort: senior citizens.
Treatment for osteoporosis may also help prevent gum disease, according to new University at Buffalo research that examined the prevalence of periodontitis in postmenopausal women.
The treatment of osteosarcoma, the most common tumor of bone, is challenging. A study led by The University of Texas MD Anderson Cancer Center found a drug known as bone metastasis-targeting peptidomimetic (BMTP-11) has potential as a new therapeutic strategy for this devastating illness.
Two University of Kentucky researchers have been awarded a $2.1 million, five-year grant to study how massage might aid in the recovery of muscle mass and reduce muscle atrophy, with implications for the elderly, the ill, and those recovering from injury.
In a new study published in Prosthetics and Orthotics International, Mayo Clinic researchers describe the direct medical costs of falls in adults with a transfemoral amputation. In this type of amputation, the leg is amputated above the knee. This work “provides a comparison for policymakers when evaluating the value of more expensive … technologies,” say the authors.
JFK promoted an image of himself as a young, healthy, strong-bodied man. But this image belies the truth: that Kennedy’s life was plagued by illnesses and he required strong medication to perform his tasks as president. This paper sheds light on JFK’s back problems and how they affected his life.