Feature Channels: Cardiovascular Health

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UT Southwestern Medical Center geneticist Dr. Helen Hobbs is the 2018 recipient of the Harrington Prize for Innovation in Medicine for her discovery of a novel way to reduce cholesterol. Dr. Hobbs, Director of the Eugene McDermott Center for Human Growth and Development, Professor of Internal Medicine and Molecular Genetics, is the fifth recipient of the Harrington Prize and the first woman to be honored.

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Researchers have identified a therapeutic target to prevent or delay heart failure from pressure overload of the heart, and a potential biomarker for the same. They say their animal studies carry clinical and translational potential.

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Announcement of the fifth annual Harrington Prize for Innovation in Medicine being awarded to Helen H. Hobbs, MD, investigator of the Howard Hughes Medical Institute and Professor of Internal Medicine and Molecular Genetics at the University of Texas Southwestern Medical Center.

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Among U.S. teenagers and young adults with severe obesity, a new study finds that only a small percentage undergo weight loss surgery, even though it is broadly considered the most effective long-term weight loss therapy. The study results, from high-volume surgical centers across five states, will be presented Monday at ENDO 2018, the Endocrine Society’s 100th annual meeting in Chicago, Ill.

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Oral micronized progesterone (OMP) may diminish hot flashes and night sweats in perimenopausal women, new research from Canada reports. The results will be presented on Monday, March 19 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

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An Ohio integrated health system and a national social enterprise have announced a new alliance to mobilize tens of millions of dollars for underinvested communities—starting with a $45 million effort to scale up economic opportunity and improve health outcomes in Toledo and the surrounding region over the next decade.

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New research presented at ENDO 2018 links semen count to other health problems

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Hospitalized patients with stable coronary artery disease (CAD) may need frequent glucose monitoring to prevent hypoglycemia and death, new research reports. The results will be presented in a poster on Saturday, March 17 at ENDO 2018, the annual 100th meeting of the Endocrine Society in Chicago, Ill.

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Van Andel Research Institute (VARI) Chief Scientific Officer Peter Jones, Ph.D., D.Sc., will be awarded an honorary doctorate from South Africa’s Stellenbosch University (SU) in recognition of a lifetime of scientific achievement and dedication to improving cancer treatment.

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Older patients with colorectal cancer are at an increased risk of developing cardiovascular disease and congestive heart failure, according to a study published in Journal of Clinical Oncology. The study also finds that morbidities such as diabetes and hypertension negatively interact with chemotherapy designated for colorectal cancer, which adds to the patient’s increased risk for cardiovascular morbidity.

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Scientists are one step closer to understanding how cells reshape their surfaces to internalize material from their surroundings, thanks to collaboration among researchers from two South Dakota universities and the National Institutes of Health.

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A 12-week mobile health, or mHealth, program not only kept cardiac rehab patients from losing ground, it appeared to help them maintain and even gain fitness.

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A new, large-scale study – led by researchers at the Smith Center for Outcomes Research in Cardiology at Beth Israel Deaconess Medical Center (BIDMC) and published online today in Circulation: Cardiovascular Quality and Outcomes – examined the relationship between 30-day episode spending for inpatient and post-discharge care and patient mortality following a hospital admission for heart attack.

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Physician-researchers from the Cardiac Center at Children’s Hospital of Philadelphia (CHOP) presented new findings on pediatric cardiovascular disease at the American College of Cardiology’s 67th Annual Scientific Session & Expo 2018 in Orlando, Fla. Among many abstracts presented were emergency department visits in patients with congenital heart disease, social risk factors for readmission, factors predicting mortality after prolonged critical illness and more.

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Largest study to date addressing the prevalence of metabolic abnormalities in testicular cancer survivors who received prior chemotherapy publishes findings in the latest issue of JNCCN

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Whether caused by an undetected birth defect or by a heart attack (myocardial infarction), when a heart sustains damage, it can be difficult to repair.

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The Great Recession, spanning 2008 to 2010, was associated with heightened cardiovascular risk factors, including increased blood pressure and glucose levels.The connections were especially pronounced among older homeowners and people still in the work force,

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Genetic mutations linked to heart disease have been considered a leading cause of sudden infant death syndrome, but a new study by Mayo Clinic, British and Danish researchers finds they are to blame for far fewer SIDS deaths than previously thought. The findings are opening new lines of inquiry into possible causes of the syndrome and may help prevent unnecessary genetic testing of surviving family members. The study results appear in the Journal of the American College of Cardiology.

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Las mutaciones genéticas vinculadas con la cardiopatía han sido consideradas como la causa principal del síndrome de muerte infantil súbita, pero un nuevo estudio de Mayo Clinic con investigadores británicos y daneses descubrió que son culpables de muchas menos de esas muertes de lo que se pensaba.

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Two types of blood pressure medications — alpha blockers and alpha 2 agonist — show increased variability in blood pressure measurements between doctor visits, which is associated with an increased risk of death, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.

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Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have found that incorporating underused, but available, imaging technologies more precisely predicts who’s at risk for heart attacks and similar threats — in time to prevent them.

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Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have found that incorporating underused, but available, imaging technologies, such as PET/CT scans, more precisely predicts who’s at risk for heart attacks and similar threats — in time to prevent them.

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The stress of open-heart surgery significantly reduces patients’ vitamin D levels, but aggressive supplementation with vitamin D3, just before and after surgery, can completely eliminate the observed drop in vitamin D, researchers have found.

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African-American men successfully lowered their high blood pressure to healthy levels when aided by a pharmacist and their local barber, according to a new study from the Smidt Heart Institute.

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Protein pathways that are closely linked to changes in both triglyceride and hemoglobin A1c levels in diabetic patients have been identified in new research by the Intermountain Medical Center Heart Institute in Salt Lake City.

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Patients who undergo a transcatheter aortic valve replacement, or TAVR — a minimally-invasive surgical procedure that repairs a damaged heart valve — experienced a significant increase in their quality of life, according to a new study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

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Doctors often cite the high price of a prescription drug as a reason they don't prescribe it, while patients similarly say that cost is a main reason they quit taking a drug. Removing this financial barrier might increase the use of evidence-based therapies, improve patient adherence to those medications, and potentially save lives. That theory was tested in a study of heart attack survivors led by the Duke Clinical Research Institute; findings were presented March 11 at the American College of Cardiology annual scientific sessions meeting in Orlando.

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Data presented from a Late-Breaking Clinical Trial has the potential to change the standard of care for HER2-positive breast cancer patients undergoing chemotherapy.

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Today, in a late-breaking featured clinical research session at the American College of Cardiology Scientific Sessions 2018, researchers from Penn Medicine present first-of-its-kind data on the impact of real-time CYP2C19 genotype results when prescribing antiplatelet drugs in the clinic.

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Doctors evaluating patients for blockages in the heart are aided by having a good roadmap of the vascular terrain before they can insert stents to clear the impasse. Two technologies have been used with equal success, but now a study presented March 10 at the American College of Cardiology annual meeting by Duke cardiologists shows that the newer method carries a much lower cost, potentially saving each patient at least $800.

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Patients who receive cardiac positron emission testing (PET) imaging instead of single photon emission computed tomography (SPECT) scan experienced a significant increase in the detection of severe obstructive coronary artery disease, according to researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

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ORLANDO: Cleveland Clinic researchers found that implementing a four-step protocol for the most severe type of heart attack not only improved outcomes and reduced mortality in both men and women, but eliminated or reduced the gender disparities in care and outcomes typically seen in this type of event. The research was presented at the American College of Cardiology’s 67th Annual Scientific Session and published in the Journal of the American College of Cardiology.

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Hackensack Meridian Health Bayshore Medical Center has resumed normal operations, accepting all emergency patients into the Emergency Department and continuing regularly scheduled procedures in the wake of needed repairs after a small fire and water damage forced the temporary closure of a limited number of inpatient care areas on February 25. As a result, the hospital also elected to transport patients to nearby Hackensack Meridian Health hospitals and to divert ambulances.

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Children with mitochondrial diseases who suffered acute metabolic strokes benefited from rapid intravenous treatment with the amino acid arginine, experiencing no side effects from the treatment. In half of the stroke episodes, patients showed clinical improvements in symptoms such as seizures and partial paralysis.

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Heart-attack sufferers who receive treatment during periods when interventional cardiologists are away at academic conferences are more likely to survive in the month after their heart attack than patients receiving treatment during nonmeeting days.

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A simple dietary supplement (L-arginine) was found to improve birth outcomes, paving the way for future clinical trials to test this inexpensive and safe intervention.

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One of the nation’s leading cardiologists is challenging the new hypertension guidelines, perhaps sparing up to 10 million people from unnecessarily aggressive blood pressure treatments. His team’s study results appear March 7 in the Journal of the American College of Cardiology.

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UC San Diego Health is the first hospital in California to use the fifth generation troponin test to detect damage to the heart. The test was approved in the United States in 2017.

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Julie Work always ate healthy and exercised regularly. Then, she passed out behind the wheel, went to a cardiologist and learned she needed a pacemaker. After recovery, she signed up for exercise boot camp and pushed herself to the limit. She needed to two pacemaker adjustments to keep up with her intense exercise regime.

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A study of mouse healing after severe heart attacks focused on the heart and spleen, measuring types and numbers of immune cells; types and amounts of lipid signaling compounds; expression of enzymes that produce those signaling compounds; and which enzymes are key to resolution of inflammation.

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SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today in Cell Reports, also identified several potential therapeutic targets that could prevent or reverse the effects of LCM.

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Giving birth to a child can be described as a sacred, spiritual and life-changing experience. It can also be fraught with pain, fear, complications and injury to both child and mother. For Dr. Steve Corns, associate professor of engineering management and systems engineering at Missouri University of Science and Technology, the key to removing some of the uncertainty associated with giving birth may lie not with woman or man, but with machine — machine learning, to be precise.

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A study published in the March 5 online edition of the Proceedings of the National Academy of Sciences (PNAS) describes how the supercomputers at the San Diego Supercomputer Center at UC San Diego were used to simulate the merger of a G-protein “mimetic nanobody” to a G-protein-coupled receptor (GPCR), the largest and most diverse group of membrane receptors in animals, plants, fungi, and protozoa.

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New research from the Endocrine Society and Avalere Health finds that clinicians lack the resources to identify, assess and manage patients who are at a high risk of developing hypoglycemia, or episodes of dangerously low blood sugar.

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Physicians at Ohio State University are taking an innovative approach to improve care for patients receiving aortic valve replacements. They’re working alongside biomedical engineers from Ohio State’s College of Engineering, who have developed a way to model and predict potential complications so they can be avoided.

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The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn’t much help in predicting which nanoparticles will successfully enter the cells of living animals.

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Chest Pain Centers recognized for providing necessary care, resources to patients with heart attack symptoms.

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A new study debunks the “obesity paradox,” a counterintuitive finding that showed people who have been diagnosed with cardiovascular disease live longer if they are overweight or obese compared with people who are normal weight at the time of diagnosis.