The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the opioid epidemic, a University of Pittsburgh Graduate School of Public Health analysis revealed today.
The University of Texas at El Paso’s Minority AIDS Research Center (MARC) is the subrecipient of a $1 million implementation grant to target substance use disorders and opioid use disorders in five rural counties along the Texas-Mexico border.
Abandoned Buildings, Fear of Calling Police Contribute to High Rate of Fatal Overdoses in Philadelphia, New Study Shows
The United States has seen a 200% increase in the rate of deaths by opioid overdose in the last 20 years. But many of these deaths were preventable. Naloxone, also called Narcan, is a prescription drug that reverses opioid overdoses, and in more than 40 states — including Pennsylvania — there is a standing order policy, which makes it available to anyone, without an individual prescription from a healthcare provider.
Luis M. Tuesta, Ph.D., assistant professor in the Department of Psychiatry and Behavioral Sciences at the University of Miami Miller School of Medicine, has been awarded the Avenir Award from the National Institute on Drug Abuse, part of the National Institutes of Health, to study the epigenetic mechanisms of microglial activation and their role in shaping the behavioral course of opioid use disorder.
While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests. People who took acetaminophen rated activities like “bungee jumping off a tall bridge” as less risky than people who took a placebo.
To better understand the effect of the COVID-19 pandemic on cannabis and CBD use, the UCLA Cannabis Research Initiative has launched the Cannabis, CBD and COVID Survey.
As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor. Now UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA receptor. The findings were published online today in the journal Nature.
In a study, a team of Penn State researchers report that an algorithm they developed may be able to spot illicit online pharmacies that could be providing customers with substandard medications without their knowledge, among other potential problems.
People have traded in nightclubs and dance festivals for virtual raves and Zoom happy hours as a result of lockdowns during the COVID-19 pandemic—yet, many are using drugs in these socially distanced settings, according to a new study by researchers at NYU Grossman School of Medicine and the Center for Drug Use and HIV/HCV Research at NYU School of Global Public Health.
In the midst of the COVID-19 pandemic, opioid misuse and addiction continue to devastate communities around the US.
FACULTY Q&ABoth fatal and nonfatal overdoses have increased this year compared to last, according to a recent report by the Overdose Data Mapping Application Program. And, anecdotal information suggests that compared to last year, people in recovery are relapsing at alarming rates.Faculty from the University of Michigan School of Nursing’s Center for the Study of Drugs, Alcohol, Smoking and Health discuss why the pandemic has hit people with substance abuse problems especially hard and the expanded role of virtual recovery programs.
Mizuho OSI®, a leading manufacturer of specialty surgical tables and pressure injury abatement solutions would like to announce the publication of a new clinical study titled “23-hour Total Hip Replacement Requiring Only 3.5 Opioid Pills Through 6 Weeks: A Non-selected Prospective Consecutive One Year Cohort”, by Andrew Wickline MD, now appearing in the peer-reviewed Journal of Orthopedic Experience & Innovation (JournalOEI)
A recent study from IUPUI found risk factors for substance use disorder affect age groups differently and proposes a primary prevention strategy for substance use disorder that is individualized for people within defined age groups.
Watch live and recorded press conferences at https://www.acs.org/content/acs/en/pressroom/news-room/press-conferences.html. Press conferences will be held Monday, Aug. 17 through Thursday, Aug. 20, 2020
Both fatal and nonfatal overdoses have increased this year compared to last, according to a recent report by the Overdose Data Mapping Application Program. And, anecdotal information suggests that compared to last year, people in recovery are relapsing at alarming rates. Faculty from the University of Michigan School of Nursing's Center for the Study of Drugs, Alcohol, Smoking and Health discuss why the pandemic has hit people with substance abuse problems especially hard and the expanded role of virtual recovery programs.
A press conference on this topic will be held Tuesday, Aug. 17, at 9 a.m. Eastern time online at www.acs.org/fall2020pressconferences.
University of Wisconsin–Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies. These antibodies may contribute to some of the negative side effects of long-term opioid use.
Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.
The “secret shopper” study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.
Affiliates with Notre Dame’s Wilson Sheehan Lab for Economic Opportunities found that greater exposure to the opioid crisis increases the chance that a child’s mother or father is absent from the household and increases the likelihood that he or she lives in a household headed by a grandparent.
Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought.
Sanford Burnham Prebys Medical Discovery Institute has been awarded a $4.5 million grant from the National Institutes of Health (NIH) to identify new therapies for mental health disorders. The research will be headed by Layton Smith, Ph.D., and Michael Jackson, Ph.D., of the Institute’s Conrad Prebys Center for Chemical Genomics. The funding supports the discovery of new classes of drugs that target “orphan” receptors to treat psychological conditions such as schizophrenia, depression, anxiety and substance abuse.
Drug overdoses are psychologically traumatic events that can lead to symptoms of post-traumatic stress disorder (PTSD), according to a study focused on female sex workers in Baltimore City led by researchers at the Johns Hopkins Bloomberg School of Public Health.
A longitudinal study of more than 230 teens and young adults in Washington state finds that teens may be more likely to use marijuana following legalization – with the proliferation of stores and increasing adult use of the drug -- than they otherwise would have been.
Johns Hopkins researchers have demonstrated that behavior therapy that exposes people to memories of their trauma doesn’t cause relapses of opioid or other drug use, and that PTSD severity and emotional problems have decreased after the first therapy session.
Tufts awards seed funding to 8 projects that seek to address the complex individual & community challenges wrought by the opioid epidemic. The inaugural awards of the Tufts Initiative on Substance Use and Addiction demonstrate a multidisciplinary drive to address this pressing public health crisis.
A new study by researchers at the Johns Hopkins Bloomberg School of Public Health found that the odds of a fatal opioid overdose were 1.5 times higher for individuals with one to two visits to the emergency department for any medical issue than for people with no hospital visits.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Funded by the Defense Advanced Research Projects Agency, a team of internationally acclaimed researchers led by UNC School of Medicine’s Bryan L. Roth, MD, PhD, aims to create new medications to effectively and rapidly treat depression, anxiety, and substance abuse without major side effects.
Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer side effects, according to a new study from an international team of researchers. The study, published in Proceedings of the National Academy of Sciences (PNAS), was conducted using cells from humans and mice with inflammatory bowel disease, which can cause chronic pain.
In a sign that designer drugs are becoming more prevalent in Australia, synthetic cathinones – commonly known as ‘bath salts’ – have been detected in the nation’s wastewater in the largest study of its kind in the country.
Fentanyl is not typically part of hospital tests for illicit drug use, however, a new University of Maryland study found after expanding testing that fentanyl, linked to most fatal overdoses in Maryland, tops the list of drugs detected in overdose patients at two Baltimore hospital ERs. The researchers suggest addition of fentanyl to routine drug tests.
A study led by University of Kentucky Markey Cancer Center researchers showed that patients who already used opioids, sedatives or antidepressants prior to colorectal surgery experience significantly more complications post-surgery.
The $2.7 million grant from the National Institutes of Health will enable researchers to identify interventions that will lead to a healthier, more resilient Native American community.
Middle-aged and older adults who identify as lesbian, gay, or bisexual have higher rates of using certain substances in the past year than those who identify as heterosexual, according to a new study led by researchers at NYU Grossman School of Medicine and the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health.
Users of high-potency cannabis are four times more likely to report associated problems, and twice as likely to report anxiety disorder, than users of lower-potency strains, according to new research from the University of Bristol.
Of nearly 6,500 commercially insured patients treated in EDs nationwide for an overdose or other opioid-related medical complications, only 16 percent accessed opioid use disorder (OUD) medications or another form of treatment within three months of the ED visit.
S&T-developed Chemical Agents Reactions Database can help federal, state and local agencies check if chemicals found in illegal labs can make illicit drugs, poisons or warfare agents.
Prevention efforts to combat the opioid crisis by limiting early exposure are working in the pediatric population, according to a study released as part of the American Academy of Orthopaedic Surgeons’ (AAOS) Virtual Education Experience. The study found that between 2004 and 2017 opioid prescription rates decreased from 60% to 27.8%, a 52% drop, in pediatric patients between 10-18 years old who sought care for a minor fracture or dislocation in an acute care setting. However, patients in the South and Midwest were more frequently prescribed opioids, pointing to a need for further preventative measures.
When Kentucky Gov. Andy Beshear announced the early release of some Kentucky inmates due to COVID-19 concerns, the team behind the HEALing Communities Study worked quickly to fast-track one of the evidence-based practices for preventing opioid deaths that was due to launch later this year: the distribution of naloxone to individuals at highest risk for overdose, particularly those being released from local jails.
Job skills training for low-income youth does more than just help them get better jobs – it makes them significantly less likely than others to use some illicit drugs, even 16 years later.
Is the lockdown leading us to drink more alcohol or spend more time gambling online or watching pornography? Researchers today launch a survey aimed at tracking how our habits have changed in response to our forced isolation.
A new West Virginia University research collaborative is working to address the many challenging conditions facing the state and Appalachia.
UAB is launching a pilot program aimed at getting more opioid users into treatment, using telemedicine in three rural counties and emploing the Alabama One Health Record®, a statewide health information exchange, to track outcomes in these patients.
Offering $750 to emergency medicine physicians exponentially increased those trained to prescribe buprenorphine.
The generation a person was born into – Silent Generation, Baby Boomer, Generation X or Millennial – strongly predicts how likely they are to die from a drug overdose, and at what age. Within each generation, there was a steady march toward greater overdose risk at younger ages.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
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