In a new study, Johns Hopkins researchers found that fewer than half of interviewed caregivers for Baltimore preschool children with asthma were prepared to administer medication for routine management or emergency response to a child's chronic condition.
University of Colorado Cancer Center study shows that common laboratory tests used to determine ROS1 status may return false-negative results, meaning that some patients who could benefit from ROS1-directed therapy may be slipping through the cracks.
Mice deficient in innate lymphoid cells are vulnerable to lethal infection by the bacterial pathogen Yersinia enterocolitica (YE), which causes some forms of food poisoning. Moreover, activation by a cytokine called LIGHT, which is a member of the tumor necrosis factor (TNF) superfamily, is necessary for ILCs to mount an anti-bacterial response.
The batteries of the future may be made out of paper. Researchers at Binghamton University, State University at New York have created a biodegradable, paper-based battery that is more efficient than previously possible
Scientists identify a safe drug that for the first time could treat – and possibly reverse – the thickening of lung artery walls in pulmonary arterial hypertension; clinical trial is expected in 2019
A new study at Texas Biomedical Research Institute is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to establish replication.
Field history matters when trying to apply the optimal amount of nitrogen for sweet potato crops. Cover crops grown in the same plots prior to sweet potato crops affected how much nitrogen was needed.
In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.
Inspired by elements found in nature, researchers at the University of New Hampshire say the puzzle-like wavy structure of the delicate seed coat, found in plants like succulents and some grasses, could hold the secret to creating new smart materials strong enough to be used in items like body armor, screens, and airplane panels.
A team led by scientists at Berkeley Lab found a way to make a liquid-like state behave more like a solid, and then to reverse the process.
Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications.
The second annual edition of “Forces On and Within Cells, a special issue of Molecular Biology of the Cell, the peer-reviewed journal of the American Society for Cell Biology (ASCB), launched August 8, online.
Sleep-related infant deaths are associated with bed-sharing, sleeping position, poverty and other factors
Jorge Henao-Mejia will work to uncover how minute organisms in the gut contribute to obesity and type 2 diabetes, findings which could pave the way from new treatments to reduce the ever-growing number of people diagnosed with these serious medical conditions.
Young children and their families in poor communities were able to make some achievable and sustainable behavioral changes during the longest and largest obesity prevention intervention, but, in the end, the results were insufficient to prevent early childhood obesity.
The first-ever computation of an atomic nucleus, the deuteron, on a quantum chip demonstrates that even today’s rudimentary quantum computers can solve nuclear physics questions.
Virtually all functions in our bodies require precise interactions between radically different types of molecules. Researchers at The University of Texas at Dallas are pursuing what differentiates a fruitful encounter from a dud.
Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills called statins can effectively treat the disease.
Not only can your smartphone serve as your wallet, watch and map, it can also be your digital security blanket. In a new study led by the University of California, Irvine, researchers found that when people are in awkward social situations, having their phones with them offers comfort and helps relieve feelings of isolation.
Proton-irradiated thorium targets are successfully mined for therapeutic radium isotopes.
A study led by researchers at Indiana University has found that human changes to rivers and streams in the United States and Canada do not isolate these natural resources from the effects of climate change.
"In humans, being able to tweak levels of TTR degradation could act as a means of stopping TTR toxicity."
روتشستر، مينيسوتا. – حدد فريق البحث الذي تتولى قيادته Mayo Clinic جينات معينة ترتبط بزيادة خطر الإصابة بسرطان الثدي الثلاثي السلبي. وقد تم نشر أبحاث الفريق اليوم في مجلة المعهد الوطني للسرطان.
由Mayo Clinic领导的一个研究小组已经确认了与三阴性乳腺癌（triple-negative breast cancer）风险增加相关的特定基因。 他们的研究成果于今天发表在《国家癌症研究所杂志》（Journal of the National Cancer Institute）上。
- Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Salk Institute for Biological Studies, have generated the first single cell resolution atlas of genes that control the formation of breast tissue. The atlas provides a comprehensive molecular map that will be used to help researchers understand how breast cancers form and to pinpoint new ways to prevent, diagnose, and treat the disease.
Getting wisdom teeth removed may be a rite of passage for many teens and young adults, but the opioid painkiller prescriptions that many receive could set them on a path to long-term opioid use, a new study finds. Young people who filled an opioid prescription were nearly 2.7 times as likely as peers to still be filling opioid prescriptions months later.
An intervention designed to promote healthy growth that taught first-time moms how to respond with age-appropriate responses to their babies’ needs resulted in children having lower body mass indexes (BMIs) when they were three years old.
400 kilometers above Earth, researchers examined waves in complex plasma under microgravity conditions and found that the microparticles behaved in nonuniform ways in the presence of varying electrical fields. They report some of the first findings from the Plasma-Kristall 4 experiment, a collaboration between the European Space Agency and the Russian State Space Corporation Roscosmos, in Physics of Plasmas.
In nature, the nuclear reactions that form stars are often accompanied by astronomically high amounts of energy, a challenge for nuclear astrophysicists trying to study these reactions; the chances of re-creating such a spark are unfathomably low. However, after recent renovations to its accelerator, one laboratory reported record-breaking performance. Following six years of upgrades to the Electron Cyclotron Resonance Ion Source at the Laboratory for Experimental Nuclear Astrophysics, researchers report improved results, discussed in Review of Scientific Instruments.
Metastasis is a leading contributor to many deaths related to cancer, but the exact mechanisms for how broken cellular function appears in cells far removed from a cancer’s primary tumor remain an area of ongoing research. Scientists at the University of Minnesota Twin Cities confirmed a link between healthy-tumor hybrid cells and metastatic tumors for the first time in live animals. In APL Bioengineering, they discuss how they studied the distinct, heterogenous gene expression profiles found in human hybrid cells and how hybrid cells spontaneously occur in mouse models.
An in-depth study of retired football and hockey players—including cognitive, psychological, and brain imaging techniques—finds no increase in the rate of early-onset dementia, reports the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of America, JHTR is published by Wolters Kluwer.
Uma equipe de pesquisa liderada pela Mayo Clinic identificou genes específicos associados a um maior risco de desenvolver câncer de mama triplo-negativo. A pesquisa foi publicada hoje no Journal of the National Cancer Institute.
روتشستر، مينيسوتا. – أشارت دراسة أولية نُشرت في عدد أغسطس الصادر من Mayo Clinic Proceedings أن بكتيريا الأمعاء قد تكون مسؤولة لدى بعض الأشخاص عن عدم قدرتهم على إنقاص الوزن، على الرغم من التزامهم باتباع نظام غذائي صارم وتمارين رياضية منتظمة Mayo Clinic Proceedings.
With obesity continuing to rise in America, researchers decided to look at a sample of college students to better understand how drinking affects what they eat, both that night and for their first meal the next day.
The warming ocean may cause the larvae of bottom-dwelling snails to hatch earlier in the spring, when waves are larger, potentially impacting their ability to survive and serve as food for other sea creatures. A Rutgers University–New Brunswick study sheds new light on the sensory organs the snail larvae use to feel – and perhaps even hear – whether the water is turbulent or wavy, and improve their odds of being carried to a good habitat where they can settle down as adults.
Using genetic sequencing to understand the evolutionary relationships among pathogens, an international team of researchers—including several from the Center for Drug Use and HIV/HCV Research (CDUHR) at New York University—has developed a new method to determine how effective interventions are against the spread of infectious diseases like HIV.
Johns Hopkins scientists report they have identified two potential new drug targets for the treatment of HIV. The finding is from results of a small, preliminary study of 19 people infected with both HIV—the virus that causes AIDS—and the hepatitis C virus. The study revealed that two genes—CMPK2 and BCLG, are selectively activated in the presence of type 1 interferon, a drug once used as the first line of treatment against hepatitis C.
A research team led by Fergus Couch, Ph.D., a geneticist at Mayo Clinic, has identified specific genes associated with an increased risk for developing triple-negative breast cancer. Their research was published in the Journal of the National Cancer Institute.
An Australian study of midwives’ views on water immersion during labour and birth shows almost 90 per cent believe the practice should be offered to all pregnant women.
Un equipo investigativo dirigido por el Dr. Fergus Couch, genetista de Mayo Clinic, identificó los genes específicos que se relacionan con mayor riesgo para cáncer de mama triple negativo. El estudio se publicó en la Revista del Instituto Nacional del Cáncer.
Researchers at the Department of Energy’s SLAC National Accelerator Laboratory have developed a new imaging technique to better understand the mechanisms that lead to hearing loss when aminoglycosides are introduced to the body. Using the lab’s Linac Coherent Light Source (LCLS) X-ray laser and Stanford Synchrotron Lightsource (SSRL), SLAC researchers, in collaboration with researchers at Stanford University, were able to observe interactions between the drugs and bacterial ribosomes at both extremely low and room temperatures, revealing never-before-seen details.
Penn Team Eradicates Hepatitis C in 20 Patients Following Lifesaving Transplants from Infected Donors
Bangladesh, Haiti, Malawi, Nepal and Tanzania each has fewer than five health facilities that can properly diagnose and treat cardiovascular diseases, chronic respiratory diseases and diabetes, a new UCLA study reports.
Prescriptions for diabetes medications increased in the first two years after states expanded eligibility for Medicaid as part of the Affordable Care Act, compared to states that didn’t expand Medicaid, according to a new analysis by researchers from UChicago and USC.
Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods of time.
For a new study, UF/IFAS researchers used nine years of data to find out whether snail kites are reproducing after they move, and how these findings might change conservation strategies.
Sulfur isotopes can serve as tracers of atmospheric oxygen, and new data collected from the present-day atmosphere in China by an international team of researchers, led by the University of California San Diego, indicate remarkable similarity to the isotopic footprint found in ancient rocks. This opens up new interpretations of the Archean Period’s sulfur isotope sedimentary signature—a proxy for the origins and evolution of atmospheric oxygen and early life on Earth.
A review of nearly 582,000 heart attack cases over 19 years showed female patients had a significantly higher survival rate when a woman treated them in the ER, according to research from faculty at the University of Minnesota-Twin Cities, Washington University in St. Louis and Harvard.
Does digital eyestrain cause lasting damage? Should children use reading or computer glasses? As kids go back to school this month for more time with screens and books, the American Academy of Ophthalmology is arming parents with the facts, so they can make informed choices about their children’s eye health.
Researchers have found an important contributor to heart pathology caused by the cancer drug doxorubicin — disruption of metabolism that controls immune responses in the spleen and heart. This allows chronic, non-resolving inflammation that leads to advanced heart failure.
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