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Transplant Drug Could Boost the Power of Brain Tumor Treatments, U-M Study Finds

Every day, organ transplant patients around the world take a drug called rapamycin to keep their immune systems from rejecting their new kidneys and hearts. New research suggests that the same drug could help brain tumor patients by boosting the effect of new immune-based therapies.

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A reporter's PressPass is required to access this story until the embargo expires on 1-Oct-2014 1:00 PM EDT

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Surprising Diversity of Antibody Family Provides Clues for HIV Vaccine Design

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Scientists at The Scripps Research Institute (TSRI) have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine.

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Imaging Studies Open a Window on How Effective Antibodies Are Formed

Sometimes, in order to understand what’s happening in the immune system, you just have to watch it. By imaging the immune response, researchers have observed how two types of immune cells, T and B cells, interact with one another during a critical period following infection in order to prepare the best antibodies and establish long-lasting protection.

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Baylor Research Institute Immunology Researchers Obtaining Promising Results with Multiple Sclerosis Vaccine

Thanks to new insights related to dendritic cell vaccines, researchers are investigating a potential vaccine for MS treatment and prevention at the Baylor Institute for Immunology Research (BIIR), a division of Baylor Research Institute. If future research supports early findings, the study could mark an important first in that it attacks MS early while preserving the immune system.

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New Rules for Anticancer Vaccines

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Scientists have found a way to find the proverbial needle in the cancer antigen haystack. The results have the potential to completely change current approaches to generating anticancer vaccines.

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New Insights on an Ancient Plague Could Improve Treatments for Infections

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Dangerous new pathogens such as the Ebola virus invoke scary scenarios of deadly epidemics, but even ancient scourges such as the bubonic plague are still providing researchers with new insights on how the body responds to infections.

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Cancer and the Immune System: A Double-Edged Sword

During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. Researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging with immune system cells and changing the latter’s response to the tumor – for good and bad.

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Gut Bacteria Tire Out T Cells

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Leaky intestines may cripple bacteria-fighting immune cells in patients with common variable immunodeficiency (CVID), a rare hereditary disease. The study may explain why these patients suffer from recurrent bacterial infections.

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T-Bet Tackles Hepatitis

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A single protein may tip the balance between ridding the body of a dangerous hepatitis virus and enduring life-long chronic infection, according to researchers in Germany.

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