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Immunology

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Medicine

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Merkel cell carcinoma , immune therapy, Immunotherapy, Skin Cancer, Cancer, “killer” (CD8) T cells , Cd8 T Cells, Paul Nghiem, MCC, KLL, Natalie Miller, KLL-specific T cells

Immune Responses Against a Virus-Related Skin Cancer Suggest Ways to Improve Immunotherapy

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Researchers at Seattle’s Fred Hutchinson Cancer Research Center and the University of Washington say a new study suggests ways to improve immune therapy for certain cancers including a virus-associated form of Merkel cell carcinoma, a rare, aggressive skin cancer.

Medicine

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immunotheraphy, Obesity, Medical Research

Mayo Clinic Researchers Identify Cancer-Fighting Drugs That Help Morbidly Obese Mice to Lose Weight

Scientific investigations sometimes result in serendipitous discoveries which shift the investigations from one focus to another. In the case of researchers at Mayo Clinic in Arizona, studies addressing obesity’s impact on cancer treatment resulted in an unexpected discovery that shifted the focus from cancer to obesity.

Medicine

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Parents Struggle with When to Keep Kids Home Sick From School; Experts on Peanut Allergies Weigh In on New Guidelines; A Better Way to Test for Jaundice, and More in the Children's Health News Source

Click here for the latest research and features on Children's Health.

Medicine

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Leishmania, persistent infection, Latent Infection, Immune System

Persistent Infection Keeps Immune Memory Sharp, Leading to Long-Term Protection

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Microbes can persist in people for years after an illness, even in people who are healthy and immune to recurrence. Now, researchers have found a clue to this seeming paradox: Persistent microbes are constantly multiplying and being killed, keeping the immune system prepared for any new encounters.

Medicine

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"Mysterious" Non-Protein-Coding RNAs Play Important Roles in Gene Expression, NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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Greenberg Bladder Cancer Institute, Bladder Cancer Advocacy Network , BCAN, David McConkey, Cancer, bladder

Young Scientists Get Boost in Funding From Johns Hopkins and Bladder Cancer Advocacy Network

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Young scientists interested in bladder cancer research can compete for up to two awards totaling $100,000 from a joint effort between the Johns Hopkins Greenberg Bladder Cancer Institute and the Bladder Cancer Advocacy Network (BCAN).

Medicine

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Inflammatory And Autoimmune Diseases, Rheumatology, Inflammation, Fibromyalgia, Obesity, Exercise, Exercise and chronic disease, Weight Loss, Diabetes, Immunology

Exercise … It Does a Body Good: 20 Minutes Can Act as Anti-Inflammatory

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It’s well known that regular physical activity has health benefits, including weight control, strengthening the heart, bones and muscles and reducing the risk of certain diseases. Recently, researchers at University of California San Diego School of Medicine found how just one session of moderate exercise can also act as an anti-inflammatory. The findings have encouraging implications for chronic diseases like arthritis, fibromyalgia and for more pervasive conditions, such as obesity.

Medicine

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Ut Southwestern, Tuberculosis, smurf1, Macrophages, Ubiquitin, ubiquitin ligase, Autophagy

UT Southwestern Scientists Identify Protein Central to Immune Response Against Tuberculosis Bacteria

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UT Southwestern Medical Center researchers have identified a protein that is central to the immune system’s ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

Medicine

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Immunizations, Vaccines, Vaccine Safety, Trump

Trump Committee on Vaccine Safety a Concern, Could Threaten Kids' Health, According to Experts From @UChicagoMed

Medicine

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Cytomegalovirus, Microbiology And Immunology

Researchers Develop New Compound to Fight Cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus, human cytomegalovirus (CMV) from reproducing and protect immunocompromised patients, like those with HIV, on chemotherapy, with transplants and infants from the effects of the disease, according to Penn State College of Medicine researchers.

Medicine

Science

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Antibody, B Cell Receptor, Differentiation, germinal center

Tailored Organoid May Help Unravel Immune Response Mystery

Cornell and Weill Cornell Medicine researchers report on the use of biomaterials-based organoids in an attempt to reproduce immune-system events and gain a better understanding of B cells.

Medicine

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Immunotherapy, Yale Cancer Center, Bladder Cancer

Yale Expert on Novel Immunotherapy Research in Bladder Cancer

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Medicine

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CAR-T, Lymphoma, KTE-C19, Cellular Therapy, Immunotherapy, Moffitt Cancer Center

Immune Cell Therapy Shows Promising Results for Lymphoma Patients, Says Moffitt Researchers

TAMPA, Fla. – Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors. The body has two types of lymphocytes that can develop into lymphoma – B cells and T cells. B-cell lymphomas account for 85 percent of all non-Hodgkin lymphomas and 30 percent of those patients are diagnosed with diffuse large B-cell lymphoma.

Medicine

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Velculescu, Tumors, Immunotherapy, Cancer, Mutations, Johns Hopkins, Valsamo Anagnostou, checkpoint inhibitors

Cancers Evade Immunotherapy by 'Discarding the Evidence' of Tumor-Specific Mutations

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Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells.

Medicine

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Vagus Nerve Stimulation, Vagus Nerve, Vagus Nerve Stimulator, kilohertz frequency, virtual vagotomy, Inflammatory And Autoimmune Diseases, Inflammatory Arthritis, Inflammatory, IN, autoimmunde disorders, Inflammatory Bowel Disorder, Crohn's Diease, afferent , efferent

Buzzing the Vagus Nerve Just Right to Fight Inflammatory Disease

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Electrical vagus nerve stimulation can help fight inflammatory diseases like Crohn's or arthritis but can also contribute somewhat to inflammation. Engineers have tweaked the buzz to keep the good effects and minimize those less desirable. Their innovation could be adapted to existing medical devices with relative ease.

Medicine

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Peanut Allergy, Allergist, Acaai

Expert Allergist Available to Advise Parents on Preventing Peanut Allergy by Introducing Their Infant to Peanut-Containing Foods

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Medicine

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Glioblastoma, glioblastoma multiforme (GBM, Immunotherapy, Gene Therapy, Brain Cancer, Cancer, Malignant Brain Tumor, Brain Tumor

Immunotherapy, Gene Therapy Combination Shows Promise Against Glioblastoma

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In a new University of Michigan study, gene therapy deployed with immune checkpoint inhibitors demonstrates potential benefit for devastating brain cancer.

Science

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Lymphoma, Affimed, Natural Killer Cells, Cord Blood, Stem Cell

MD Anderson and Affimed Announce Clinical Immuno-Oncology Development Collaboration

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The University of Texas MD Anderson Cancer Center and Affimed N.V., a clinical stage biopharmaceutical company focused on discovering and developing highly targeted cancer immunotherapies, today announced an exclusive strategic clinical development and commercialization collaboration to evaluate Affimed’s TandAb technology in combination with MD Anderson’s natural killer cell (NK) product.

Medicine

Channels:

targeted cancer therapy, Immune Cells, nanoparticle drug delivery

New Technique Uses Immune Cells to Deliver Anti-Cancer Drugs

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Penn State biomedical engineers have created a smart, targeted drug delivery system using immune cells to attack cancers.

Medicine

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Immune Cells, Immunotherapy, Resistance

New Study Highlights Role for Immune Cells in Cancer’s Ability to Evade Immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system. One of these escape mechanisms involves a type of immune cell called myeloid-derived suppressor cells (MDSCs). A recent study led by Sharon Evans, PhD, Professor of Oncology and Immunology at Roswell Park Cancer Institute, provides new insight into how MDSCs enable tumor cells to circumvent immune attack and offer the potential for improving cancer immunotherapy. The research has been published today in the journal eLife.







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