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New Insight Into How the Immune System Sounds the Alarm

Salk scientists unveil how a critical molecule turns on T cells.

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How to Become a T Follicular Helper Cell

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Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive their differentiation had remained unclear. Now, a team of researchers at the La Jolla Institute for Allergy and Immunology has identified a pair of master regulators that control the fate of TFH cells.

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Diversion of an HIV Vaccine Immune Response by Antibodies Reactive with Gut Microbiome

A recent HIV vaccine trial testing the HIV envelope as an immunogen was unsuccessful for protection against HIV infection. A new study has found that this vaccine selectively recruited antibodies reactive with both the HIV envelope and common intestinal microbes — a phenomenon previously reported by the same investigators to occur in the setting of acute HIV infection.

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Evolutionary War Between Microorganisms Affecting Human Health, IU Biologist Says

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Health experts have warned for years that the overuse of antibiotics is creating “superbugs” able to resist drugs treating infection. Now scientists at Indiana University and elsewhere are finding evidence that an invisible war between microorganisms may also be catching humans in the crossfire.

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Immunotherapy: 5 Ways to Stop Cancer

"Immunotherapy: 5 Ways to Stop Cancer" features five 1-minute animated videos that provide a quick overview of the five most common immunotherapies in use: monoclonal antibodies, checkpoint inhibitors, cancer vaccines, adoptive cell therapy, and oncolytic viruses.

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What Cancer Patients Should Know: Latest Immunotherapy News From ASCO

Learn the latest news in cancer immunotherapy for melanoma, lung cancer, leukemia, liver cancer, and other cancer types.

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Doctors at Cincinnati Children’s Remind Parents about the Importance of Vaccination

Doctors at Cincinnati Children’s Hospital Medical Center want to remind parents about the importance of immunizing their children when preparing to send their children back to school.

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Lingering Lymphocytes Lash Out Against Leishmania

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Immune cells that hang around after parasitic skin infection help ward off secondary attack. These skin squatters may prove to be the key to successful anti-parasite vaccines.

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Poverty and Child Development, Race and Heart Health, Pot to Treat Pain, and More Top Stories 21 July 2015

Other topics include genetics to predict prostate cancer, Facebook and body image, bioengineered immune cell response, and more...

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Alefacept Preserves Beta Cell Function in Some New-Onset Type 1 Diabetes Patients Out to Two Years

Individuals with new-onset type 1 diabetes who took two courses of alefacept (Amevive®, Astellas Pharma Inc.) soon after diagnosis show preserved beta cell function after two years compared to those who received a placebo.