A new study led by UNC Lineberger Comprehensive Cancer Center researchers identifies distinct patterns of side effects for prostate cancer treatments that patients could use to guide their choices.
Faced with the negative quality-of-life effects from surgery and radiation treatments for prostate cancer, low risk patients may instead want to consider active surveillance with their physician, according to a study released Tuesday by the Journal of the American Medical Association (JAMA).
Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to test the combination therapy using immune checkpoint blockades with therapies targeting myeloid-derived suppressor cells (MDSCs).
An Ontario-led international clinical trial with 1,206 men with localized prostate cancer shows that compressing radiation treatments into four weeks from eight delivers similar outcomes.
New research from Michigan State University indicates that embryonic tissue, key to the development of a baby’s gender, could contribute to an enlarged prostate, or BPH, in men later in life.
Endostatin, a naturally occurring protein in humans, can significantly decrease proliferation of castration-resistant prostate cells in culture, and researchers describe the physiological pathways and signaling evoked by endostatin.
Moffitt Cancer Center and its community partners will once again host the annual Men’s Health Forum on Saturday, March 18, from 8 a.m.-2:30 p.m. at the University of South Florida Marshall Student Center. This marks the 17th year of the forum and baseball legend Ken Griffey Sr. is scheduled to appear.
Men with longer exposure to the drugs finasteride and dutasteride had a higher risk of getting persistent erectile dysfunction than men with less exposure, reports a new study. The persistent erectile dysfunction continued despite stopping these drugs, in some cases for months or years. Prior to the study, there was no strong evidence the drugs cause sexual problems that continue after men stop taking them or that taking these drugs for a longer time increases the chance of experiencing sexual problems.
Cabozantinib, an FDA-approved drug for patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils – the first-responders of the immune system – to infiltrate the tumor. This novel approach, utilizing the innate immune system, produced near-complete clearance of invasive prostate cancers within 48 to 72 hours.
The clinic will help men with genetic predisposition to prostate cancer identify and monitor their risk of the disease.
A female brain’s resident immune cells are more active in regions involved in pain processing relative to males, according to a recent study by Georgia State University researchers.
Marc Bjurlin, DO, (right) director of urologic oncology at NYU Lutheran Medical Center, used state-of-the-art technology to help patient Mikhail Kurbesov beat prostate cancer.
Results from a new prospective clinical trial indicate that high-dose-rate (HDR) brachytherapy administered in a single, 19 Gray (Gy) treatment may be a safe and effective alternative to longer courses of HDR treatment for men with localized prostate cancer.
It is commonly known that testosterone levels decrease as men age, but until last year, little was known about the effects of testosterone treatment in older men with low testosterone. Today, in a group of papers published in the Journal of the American Medical Association (JAMA) and JAMA Internal Medicine, researchers found that testosterone treatment improved bone density and anemia for men over 65 with unequivocally low testosterone. However, testosterone treatment did not improve cognitive function, and it increased the amount of plaque buildup in participants’ coronary arteries.
Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of Radiation Oncology, Medical Ethics, and Health Policy at the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center.
Loss of the protein Importin 11 predicts relapse and metastasis in patients following prostate removal
A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.
Michigan State University researchers are the first to uncover reasons why a specific type of immune cell acts very differently in females compared to males while under stress, resulting in women being more susceptible to certain diseases.
Adding hormonal therapy to radiation treatment can significantly improve the average long-term survival of men with prostate cancer who have had their prostate gland removed, according to a new Cedars-Sinai study published in the Feb. 2 issue of the New England Journal of Medicine. The regimen also can reduce the frequency of spread of the cancer, the study found.
Researchers at NIBIB have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial. Prostate cancer is the fifth leading cause of death worldwide and is especially difficult to diagnose. While prostate cancer is relatively easy to treat in its early stages, it is prone to metastasis and can quickly become deadly. In order to plan how aggressively they should treat the cancer, it is important for doctors to know how far the cancer has progressed. NIBIB researchers have attempted to solve this problem by developing a radiotracer that could identify prostate cancer at all stages.
Researchers have found that prolonged exposure to high temperatures can raise both the skin and core temperature, reducing blood flow to the brain and limbs during exercise and limiting the ability to exercise for long periods. The study, the first of its kind to separate the effects of skin- versus internal-raised temperature (hyperthermia), is published in Physiological Reports.
Posttraumatic stress disorder (PTSD) can develop after a traumatic event or events. Although it is most often associated with military personnel exposed to the trauma of combat, it can also disproportionately affect vulnerable American Indian and Alaskan-Native (AI/AN) populations. Because alcohol use disorders (AUDs) also have a disproportionate impact on AI/ANs, this study compared both lifetime PTSD and past-year AUD among AI/ANs and non-Hispanic Whites (NHWs).
Australian researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body. The discovery may lead to the development of a blood test that could predict whether cancer will spread from the prostate tumour to other parts of the body.
Metastasis, or spread of a tumor from the site of origin to additional organs, causes the vast majority of cancer-related deaths, but our understanding of the molecular mechanisms behind metastasis remains limited. A research team led by Dean Tang, PhD, Chair of the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute, examined the multistep process that leads to metastasis and their work, which illuminates the role of prostate cancer stem cells that promote tumor growth and metastasis, has been published online ahead of print in the journal Nature Communications.
How we feel after 1-night stands has a lot to do with our gender -- and evolution.
The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers from the University at Buffalo and Roswell Park Cancer Institute report in a new study.
Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones. However, for some men, prostate cancer recurs despite androgen-deprivation therapy. A team of scientists led by Irwin Gelman, PhD, Professor of Oncology in the Department of Cancer Genetics at Roswell Park Cancer Institute, has identified an 11-gene signature unique to advanced recurrent prostate cancer that they believe will help to identify these aggressive and potentially fatal prostate cancers sooner. The findings have been published online ahead of print in the journal Oncotarget.
A large study of more than 9,000 men has established harmonized reference ranges for total testosterone in men that when applied to assays that have been appropriately calibrated will effectively enable clinicians to make a correct diagnosis of hypogonadism, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
As some national guidelines now recommend against routine prostate cancer screening, the overall rate of men receiving treatment for the disease declined 42 percent, a new study finds.
Johns Hopkins researchers who conducted a dozen focus groups with 70 straight and gay/bisexual Hispanic and African-American males ages 15 to 24 report that gaining a better understanding of the context in which young men grow up will allow health care providers to improve this population’s use of sexual and reproductive health care.
A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. The researchers found that targeting the components of this circuit suppresses advanced prostate cancer development.
An alternative to oral erectile dysfunction medications has been introduced: GAINSWave™ uses high-frequency acoustical waves to treat the root cause of erectile dysfunction.
For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses. The achievement, say researchers at Georgetown University Medical Center who led the research, represents a critical advance in the effort to understand the origin and drivers of this puzzling cancer — the most common in men.
6 tips from Jeff Moore, who runs the compounding pharmaceutics lab at University of the Sciences in Philadelphia, for finding the right cream or lotion to protect your skin from harsh winter weather.
According to the Centers for Disease Control and Prevention (CDC), an estimated 18 percent of men who sought help with a fertility specialist were diagnosed with a male-related infertility. Here are some factors from the Texas A&M College of Nursing that can impact your fertility.
Estrogen or progesterone makes a difference in sexual desire
UCLA researchers have discovered a previously unrecognized type of progenitor cell that, though rare in most regions of the human prostate, is found in uncommonly high numbers in inflamed areas of the gland. These progenitor cells have the ability to initiate prostate cancer in response to genetic changes. The study results suggest inflammation increases overall risk for the disease by increasing the available pool of progenitor cells that can develop into prostate cancer.
Increased stigma and discrimination can affect circadian HPA-axis functioning; the majority of previous studies have been conducted among white heterosexuals, with very little research examining HPA-axis functioning between different minorities. Individuals who identify as both sexual and racial minorities may experience increased stigma and discrimination that can affect this HPA-axis functioning. NYU researchers examined differences in diurnal cortisol rhythm between young, self-identified, white gay men and black gay men.
An international group of researchers report success in mice of a method of using positron emission tomography (PET) scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer.
A new study coauthored by BYU researchers may lead to a more accurate system for early detection, diagnosis, and treatment of prostate cancer. It’s a promising development given prostate cancer is the second most common cancer among men worldwide, responsible for 308,000 deaths in 2012 and estimated to take 26,120 lives in the U.S. alone in 2016.
Men who see themselves as playboys or as having power over women are more likely to have psychological problems than men who conform less to traditionally masculine norms, according to research published by the American Psychological Association.
Researchers at the University of Louisville School of Public Health and Information Sciences have developed a tool for framing the relationship between policy, criminal justice practices and HIV-related factors that impact racial disparities.
Prediction model created by "research parasites" published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer
University of California, Irvine health policy researchers have been awarded $1.2 million by the California Initiative to Advance Precision Medicine to develop more effective ways for prostate cancer patients and their physicians to customize treatment.
Scientists at The Wistar Institute have demonstrated how a protein called TRAP1 – an important regulator of energy production in healthy and cancerous cells – is an important driver of prostate cancer and appears to be a valuable therapeutic target for the disease.
An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.
When it comes to skin care, men have traditionally kept it simple. However, experts say more men are now pursuing healthier, younger-looking skin. Since November is National Healthy Skin Month, dermatologists from the American Academy of Dermatology say now is a great time for men to evaluate their skin care routine and learn more about how to take care of their body’s largest organ.
Twelve weeks of aerobic exercise significantly boosted testosterone levels in overweight and obese men, according to researchers from Tsukuba University and Ryutsu Keizai University in Japan. Increased levels were highest among men who exercised vigorously. The new findings will be presented at the Integrative Biology of Exercise 7 meeting in Phoenix.
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