Newly expanded partnership between nation’s leading respiratory hospital and renowned New York- based health care system celebrates successes of first year of service
Researchers at the Yale School of Medicine have identified a chemical inhibitor that limits the growth of lung tumor cells. The inhibitor works by partially disrupting glycosylation, the addition of sugar chains to proteins.
A study by researchers from The Saban Research Institute of Children’s Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants.
Steroids for women at risk of preterm birth improve lung development and reduces risk of severe respiratory distress in babies.
Worsening depression symptoms are associated with shorter survival for lung cancer patients, particularly those in the early stages of disease, according to a new U.S. study.
Researchers at the University of Illinois at Chicago have been awarded a $1.5 million grant from the Agency for Healthcare Research and Quality to study the impact of diagnostic error on outcomes for pulmonary patients and the use of lung-function testing in primary care. Studies suggest 30 to 50 percent of patients may have an incorrect diagnosis.
Penn Medicine researchers, along with colleagues at Cincinnati Children's Hospital and Boston University, have received a $5.2 million, seven-year grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) to study the cellular and molecular mechanisms that promote lung regeneration.
Moon Nahm’s groundbreaking research is on the threshold of aiding researchers in producing vaccines at prices that will propel their widespread use and help protect the estimated 1.6 million children, most of them under the age of 5, who die yearly from S. pneumoniae infections.
A survey of international members of the American Thoracic Society (ATS) found that 96 percent of respondents agreed that climate change is occurring and 81 percent indicated that climate change has direct relevance to patient care. Compared to a similar survey of American ATS members, more international physician members reported that climate change was affecting their patients “a great deal” or a “moderate amount” (69 percent international vs. 44 percent U.S.).
A Yale-led research team has identified a new blocking mechanism that acts like a dimmer switch and inhibits lung tumor cell growth.
The Perlmutter Cancer Center at NYU Langone Medical Center has named noted clinician-scientist Kwok-Kin Wong, MD, PhD, as its new Chief of Hematology and Medical Oncology.
Researchers working in four labs at UT Southwestern Medical Center have found a chink in a so-called “undruggable” lung cancer’s armor – and located an existing drug that might provide a treatment.
A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) and middle ear infection (otitis media), according to a study by researchers at Georgia State University.
Heart disease patients enrolled in a clinical trial - designed to test whether a stronger dose of the influenza vaccine can prevent death or hospitalization due to a heart attack, heart failure, stroke or pneumonia - have begun receiving their first flu shots in Toronto and Boston.
A Yale Cancer Center team completed a multi-institutional analysis of treatment options for patients with newly diagnosed EGFR-mutant non-small cell lung cancer (NSCLC) with brain metastases to determine the best option for treatment.
Members of the Global Alliance for Chronic Diseases are funding more than thirteen international research projects into the prevention and management of chronic lung diseases.
A new study led by Anurag Singh, MD, of Roswell Park Cancer Institute and presented at the American Society for Radiation Oncology (ASTRO) 2016 Annual Meeting suggests that a single high-intensity SBRT dose can be as effective as three slightly lower doses of radiation.
St. Jude Children’s Research Hospital scientists have discovered a previously unrecognized form of macrophage in mice; the immune cells survived chemotherapy and protected against life-threatening lung infections.
Two new studies from the University of Iowa suggest that gene therapy may be a viable approach for treating or preventing lung disease caused by cystic fibrosis (CF).
Jonathan Samet, M.D., M.S. of the University of Southern California Keck School of Medicine, will tackle the issue of tobacco and health, explaining how solid research can drive gains in public health.
The American Thoracic Society (ATS) and the Japanese Respiratory Society (JRS) have published new clinical practice guidelines for the diagnosis and management of lymphangioleiomyomatosis (LAM), a rare lung disease that primarily affects women of child-bearing age.
Cells in the lung are constantly exposed to oxygen and intermittently exposed to other environmental factors, resulting in a susceptibility to oxidative injury. Both alcohol use disorders (AUDs) and cigarette smoking heighten pulmonary oxidative stress, likely due to antioxidant depletion. Pulmonary oxidative stress damages innate immunity, which can contribute to increased pneumonia susceptibility and severity. This study sought to understand whether measures of pulmonary oxidative stress in upper airway fluid are comparable to measures in the lower airways, and whether either compartment is preferentially affected by AUDs and/or smoking. If upper airways’ and lower airways’ oxidative stress indices are similar, less invasive methods to assess pulmonary oxidative stress, such as mini-bronchoalveolar lavage (mini-BAL) or sputum evaluations, could be used in research and clinical settings.
David Warburton, MD, of Children’s Hospital Los Angeles (CHLA) has been awarded more than $2.3 million from the Department of Defense for the development of an innovative endoscopic device for performing noninvasive, quantitative analysis of lung epithelial cell metabolism during lung injury.
Pediatric otolaryngologist George Harris, MD, FACS, FAAP, who specializes in aerodigestive track disorders, has joined Loyola Medicine.
The American College of Radiology applauds members of the House Ways and Means Committee for standing against planned cuts to Medicare reimbursement for low-dose computed tomography (LDCT) lung cancer screening.
In a study appearing in the September 13 issue of JAMA, Jouke T. Annema, M.D., Ph.D., of the Academic Medical Center, Amsterdam, and colleagues examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung cancer.
Tuberculosis persists in many patients after they receive drug therapies, while others relapse after being successfully cured of symptoms, according to a study published in Nature Medicine. The findings highlight the importance of immune systems in eradicating the disease, and provide markers to test new treatments.
For patients with advanced lung cancer, a non-invasive liquid biopsy may be a more effective and suitable alternative to the gold standard tissue biopsy to detect clinically relevant mutations and help guide their course of treatment.
Acute exacerbations of chronic obstructive pulmonary disease, or COPD, are associated with significant long-term lung function loss, according to research published online, ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
The Society of Thoracic Surgeons (STS) officially announced the public launch of its patient website, ctsurgerypatients.org, which offers immediate and easy access to expert, multimedia content on heart, lung, and esophageal diseases and operations.
Inconsistencies across studies and sampling errors remain major barriers to understanding how the lung microbiome changes with tuberculosis, according to a review published today in Clinical Microbiology Reviews.
The U.S. Preventive Services Task Force (USPSTF) recommends screening for latent tuberculosis infection in populations at increased risk. The report appears in the September 6 issue of JAMA.
A post-marketing safety study mandated by the U.S. Food and Drug Administration has shown that a combination drug therapy for the treatment of asthma is safe and effective.
Results of a study published in PLOS ONE show that asthma risk increased 17 times when children who had bronchiolitis in the first two years of life also had a common variation of the Plasminogen activator inhibitor-1 (PAI-1) gene.
The National Institute of Allergy and Infectious Diseases (NIAID) recently awarded $149,388 to Collaborations Pharma, Inc. (CPI) to initiate a partnership with Rutgers aimed at developing a series of compounds for treating tuberculosis (TB).
Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell’s ‘fuel supply’ by targeting a cellular survival mechanism known as autophagy.
Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis.
The study compared seven different ventilation strategies. Based on data collected from 30 different trials and over 5,500 infants younger than 33 weeks’ gestational ag.,
As humans evolved over many thousands of years, our bodies developed a system to help us when we start running and suddenly need more oxygen. Now, using that innate reflex as inspiration, UCLA researchers have developed a noninvasive way to treat potentially harmful breathing problems in babies who were born prematurely.
Researchers have found that the infant airway is already colonized with bacteria when a baby is born — and this is true for infants born as early as 24 weeks gestation. The pattern of colonization appears to have an important link to later severe neonatal lung disease.
A study led by Professor Daniel Tenen, Director of the Cancer Science Institute of Singapore at the National University of Singapore, found that inhibiting a protein called BMI1 could inhibit the development of lung cancer.
Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease. A team of investigators led by Elena Levantini, PhD, a research associate in Hematology-Oncology at Beth Israel Deaconess Medical Center (BIDMC), instructor of medicine at Harvard Medical School and a member of the Harvard Stem Cell Institute, have identified a subtype of human adenocarcinoma. The research could help determine which individuals are at greatest risk of developing lung tumors that may be amenable to a new therapy to inhibit their progression.
The American Thoracic Society has issued clinical practice guidelines to help pediatricians and pediatric pulmonologists evaluate infants with recurrent or persistent wheezing. “Official ATS American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing” is published in the Society’s Aug. 1 American Journal of Respiratory and Critical Care Medicine and is available online.
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