Feature Channels: OBGYN

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Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern Medical Center researchers.

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Pregnant teens in the U.S. have long been known to face increased health risks and pregnancy complications, but a new study for the first time finds that girls ages 13 or younger who get pregnant face even greater risks. These very young girls are significantly more likely to experience preterm birth, cesarean delivery, and admission to the intensive care unit (ICU) compared to older pregnant teens.

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Once again this year, the Neonatal Intensive Care Unit (NICU) at Cedars-Sinai Guerin Children’s celebrated Halloween with special hand-sewn costumes for the medical center’s smallest babies. The costumes are designed for babies as little as 2 pounds and are based on characters in famous children’s books.

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New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

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The LJI team plans to use their new map of the Lassa virus surface glycoprotein to design a much-needed vaccine.

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UW Medicine researchers compared vaginal samples collected from 95 young women or adolescent study participants in Kenya before or after they began having sexual intercourse. They found a sharp increase in proteins that control the immune response, including IL-1β, IL-2, and CXCL8, during the first year after becoming sexually active.

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Autistic people are more vulnerable to depression and anxiety during pregnancy, according to new research from the University of Cambridge.

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尊敬的妙佑医疗国际：我的偏头痛断断续续发作已有五年了，为此我饱受折磨。最近，我发现自己平时服用的口服药物似乎也没那么有效了。我知道市面上有一些更新型的药物，但一位朋友建议我试一试Botox注射。她很认真地告诉我，正是这种药物使她的慢性头痛得到了控制。我想请问一下，Botox注射的安全性怎么样？是如何起作用的？这种药物的治疗方案是什么？需要结合使用其他头痛药物吗？答：Botox又名A型肉毒杆菌毒素，其于2010年经美国食品药品管理局批准用于治疗慢性偏头痛。这种药物并不能根治此病。使用Botox注射治疗头痛的患者通常需要每三个月接受一次注射。

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ESTIMADA MAYO CLINIC: venho sofrendo com enxaquecas intermitentes há mais ou menos cinco anos. Recentemente, a terapia oral que venho usando parece não estar mais fazendo efeito. Apesar de saber que novos medicamentos estão disponíveis, uma amiga sugeriu que eu experimentasse injeções de Botox. Ela jura que as injeções deixaram seus níveis de dores de cabeça sob controle. Essas injeções são seguras e como o Botox funciona? Qual é o cronograma de tratamento e eu também precisaria tomar outros medicamentos para dor de cabeça? RESPOSTA: a toxina Onabotulínica A, ou Botox, foi aprovada pela Food and Drug Administration (Administração de Alimentos e Medicamentos dos Estados Unidos) em 2010 para tratar enxaquecas. Não se trata de uma cura. As pessoas que recebem injeções de Botox para dores de cabeça geralmente recebem o tratamento mais ou menos a cada três meses.

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ESTIMADA MAYO CLINIC: He sufrido migraña de forma intermitente durante aproximadamente cinco años. En el último tiempo, la terapia oral que he recibido pareciera ser menos eficaz. Si bien sé que existen medicamentos más nuevos, una amiga me sugirió que pruebe las inyecciones de bótox. Mi amiga jura que el bótox controló sus dolores de cabeza crónicos. ¿Cuán seguras son estas inyecciones? ¿Cómo funciona el bótox? ¿Cuál es el plan de tratamiento? ¿También tendría que tomar otro medicamento para el dolor de cabeza? RESPUESTA: La onabotulinumtoxina A, o el bótox, fue aprobada por la Administración de Alimentos y Medicamentos en el 2010 para el tratamiento de los dolores de cabeza por migraña crónicos. No es una cura. Las personas que reciben inyecciones de bótox para los dolores de cabeza suelen recibir el tratamiento aproximadamente cada tres meses.

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Building upon a long history, the UC San Diego has launched a new Human Milk Institute to accelerate research into the nature, biology and therapeutic potential of human milk to prevent or treat both infant and adult diseases. The new institute is believed to be the first of its kind in the United States.

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On Wednesday, November 2, 2022, MacNeal Hospital will host an interactive demonstration in which members of the community can observe and try out the da Vinci surgical system. The event will be held from 11 am to 4 pm at the Oak Park lobby entrance. Acquired by Loyola Medicine in 2021, the da Vinci robots are used for minimally invasive procedures at MacNeal. In this interactive experience, members of the community have an opportunity to learn first-hand how MacNeal physicians perform urologic, gynecologic and general surgeries using this advanced technology.

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The latest articles that have been added to the Environmental Health channel.

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Women at risk of pregnancy loss who need a specialist surgical procedure could benefit from a single-stranded suture thread to reduce risk of infection, results from the C-STICH clinical trial found.

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Rates of prenatal care among foreign-born Latinx pregnant people decreased below expected levels during the 2016 presidential campaign – likely reflecting the effects of harmful anti-immigrant rhetoric, reports a study in the November issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.

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While hormone therapy was associated with higher self-reported quality of life in white women, Black women actually experienced lower overall quality of life under the same treatment.

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The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a combination approach to overcome PARP inhibitor resistance in breast and ovarian cancers, a deeper understanding of STAT3 mutations as drivers of disease progression, insights into the “obesity paradox” in men with advanced melanoma, a prognostic model for rapidly progressing vestibular schwannoma, and a role for cellular trafficking proteins in creating a metastasis-promoting lung cancer microenvironment.

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A total of 54 Mercy Medical Center physicians were recognized in Baltimore magazine’s November 2022 “Top Doctors” issue, representing 28 separate specialties.

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Currently, the U.S. leads western nations in infant mortality and cardiac birth defects are a leading cause. New research harnesses the power of AI to detect dangerous cardiac abnormalities prenatally. Resulting medical protocols implemented at birth in those at-risk could go a long way toward saving lives.

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Newly published research is the first to show that stillbirth can be inherited and tends to be passed down through male members of the family. That risk preferentially comes from the mother’s or father’s male relatives—their brothers, fathers, grandfathers, uncles, or male cousins. But the odds of a couple losing a baby to stillbirth are even greater when the condition comes from the father’s side of the family.

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Five experts from the Perelman School of Medicine at the University of Pennsylvania have been elected to the National Academy of Medicine (NAM), one of the nation’s highest honors in the fields of health and medicine. Regina Cunningham, Elizabeth Howell, Steven Joffe, Katalin Karikó, and Drew Weissman are among the 100 new members, elected by current NAM members.

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妙佑医疗国际(Mayo Clinic) 研究人员发现，借助人工智能(AI)算法来分析临产妇女的变化模式，可以帮助确定产妇能否顺利进行阴道分娩，以及阴道分娩能否确保母婴平安。这些研究结果已发表在《PLOS ONE》期刊上。

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Pesquisadores da Mayo Clinic descobriram que o uso de algoritmos de inteligência artificial (IA) para analisar padrões de mudanças em gestantes em trabalho de parto pode ajudar a identificar se o parto vaginal terá bons resultados para mães e bebês. Os resultados foram publicados na revista PLOS ONE.

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Los investigadores de Mayo Clinic descubrieron que utilizar algoritmos de inteligencia artificial para analizar patrones de cambio en las mujeres durante el trabajo de parto puede ayudar a identificar si el parto vaginal será exitoso y si se obtendrá resultados positivos tanto en la mamá como en el bebé. Los resultados de esta investigación se publicaron en PLOS ONE.

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Women who used chemical hair straightening products were at higher risk for uterine cancer compared to women who did not report using these products, according to a new study from the National Institutes of Health. The researchers found no associations with uterine cancer for other hair products that the women reported using, including hair dyes, bleach, highlights, or perms.

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Women who experience more hot flashes and night sweats during menopause may have more of a brain biomarker called white matter hyperintensities, according to a new study published in the October 12, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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The environment could be playing a critical role in the expression of polycystic ovary syndrome (PCOS) in women living in Alabama, as compared to women in California, according to a new study published in the Journal of Clinical Endocrinology & Metabolism.

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Michelle and Jeff were excited to build their new family together, but when she received the distressing news that her developing baby was diagnosed with spina bifida, she looked for the best treatment. She was referred to the world’s first stem cell clinical trial.

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Women with polycystic ovary syndrome (PCOS) in Alabama may be more likely to have excessive hair growth and insulin resistance, whereas women with PCOS in California may be more likely to have higher testosterone levels, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Researchers have discovered a novel, non-invasive way to measure blood flow to the brains of newborn children at the bedside – a method that has the potential to enhance diagnosis and treatment across medicine, a Michigan Medicine study suggests.

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Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women’s tumors do not respond to therapy.

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Johns Hopkins Children’s Center researchers will present on several different topics at the AAP Experience National Conference & Exhibition.

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A meta-analysis of 32 studies showed that the immune system within the vagina ebbs and flows, depending on menstrual-cycle stage. The analysis identified 53 distinct messages that immune cells sent to one another.

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Telemedicine-driven program cut the time from an initial new patient visit to fertility treatment from more than two months to 41 days

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Three babies have been born after receiving the world’s first spina bifida treatment combining surgery with stem cells. This was made possible by a landmark clinical trial at UC Davis Health known formally as the “CuRe Trial: Cellular Therapy for In Utero Repair of Myelomeningocele.”