Feature Channels: OBGYN

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Researchers have identified two new biological markers of cystic fibrosis (CF), a genetic disease which affects children and young adults, leaving them with lifelong health complications including digestive problems and persistent lung infections. The findings, published in the journal ACS Central Science, shed new light on the underlying mechanisms of CF and could lead to improved prognosis and better therapies for a disease which is quite variable, affecting different children in different ways, say researchers.

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In American women, breast cancer is the second most common cancer and the second leading cause of cancer death. Using data, algorithms and lab experimentation, a biomedical engineer at Washington University in St. Louis is studying breast cancer at the most basic level – the cells – to look for clues about how the cancerous cells metastasize.

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The study, conducted in mice, found that exposure to air pollution during the equivalent of the first or second trimester in humans was linked to more negative birth outcomes than exposure later in pregnancy.

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University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining failure of retinoic acid trials against breast cancer and offers a possible strategy for their use.

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Uncircumcised men with high levels of anaerobic penile bacteria at higher risk for HIV

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Saint Louis University obstetricians are leading a clinical trial at SSM Health St. Mary’s Hospital that investigates a possible approach to treat postpartum hemorrhage, the leading cause of perinatal maternal death around the world.

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Jersey Shore University Medical Center and Hackensack University Medical Center are the first hospitals in New Jersey to be recognized by the NJBC for breastfeeding supportive practices. This includes providing the availability of reasonable breaks for mothers to express milk or to nurse their child, and access to a private space for expressing milk or nursing their child.

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While research has demonstrated the positive impact a woman’s social support network and faith community can have on influencing decisions to breastfeed, little is known regarding the influence of Islamic traditions on the breastfeeding beliefs and practices of African American Muslims.

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A new study has found that children born extremely premature to women who are overweight or obese before the pregnancy are at an increased risk for low scores on tests of intelligence and cognitive processes that influence self-regulation and control, according to researchers at Wake Forest Baptist Medical Center.

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Providers in the Veterans Health Administration (VA) system vary in their testosterone prescribing practices, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. This is the first study to examine provider and site predictors of testosterone prescribing in the VA.

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Exposure to environmental pollutants during pregnancy may increase the risk of asthma for as many as three consecutive generations, according to new research.

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For the subset of women with BRCA mutations who have already had ovarian cancer, risk-reducing mastectomy might not be worth the price tag. New research from the Duke Cancer Institute finds that for many women in this unique group, prophylactic mastectomy does not produce a substantial survival gain versus breast cancer screening alone and is not cost-effective.

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A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

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While the Zika virus is primarily transmitted by mosquitoes, research has shown that the disease can affect semen and sperm and can therefore be spread through sexual intercourse.

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Heart disease is the number one killer of women. However, most women are not treated for the disease until they in their 50s and 60s. This release talks about how women with risk factors need to talk to their doctors in their 40s and get ahead of the game. Also mentions recent study on subject.

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Scientists have found a single protein—Ptbp2—controls a network of over 200 genes central to how developing sperm move and communicate. The protein works by regulating how RNA is processed during each stage of sperm development.

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A UAB obstetric surgeon will lend her skills to African women by treating obstetric fistula, a common complication of childbirth in the developing world that causes incontinence.

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St. Jude Children’s Research Hospital has advanced understanding of risk factors for premature ovarian insufficiency, which should aid identification of cancer patients most likely to benefit from fertility preservation.

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Pelvic girdle pain (PGP) is a common condition that causes pain and physical impairment, most frequently during the antepartum (before delivery) period. A new guideline for evidence-based physical therapy practice for PGP during pregnancy appears in the Journal of Women's Health Physical Therapy, official journal of the Section on Women's Health (SOWH) of the American Physical Therapy Association. The journal is published by Wolters Kluwer.

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A gel aimed at preventing HIV, which is being trialled in Africa, is only used by women with their male partner’s approval.

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The majority of reproductive-age and pregnant women who use opioids for non-medical purposes also use at least one other substance, ranging from nicotine or alcohol to cocaine, according to a University of Pittsburgh Graduate School of Public Health analysis. It was the first to look at use of multiple substances in a nationally representative group of US women age 18 to 44.

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A form of genetic variation, called differential RNA splicing, may have a role in tumor aggressiveness and drug resistance in African American men with prostate cancer, according to research published out of the George Washington University Cancer Center in Nature Communications.

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Nicole F. Steinmetz, PhD, director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

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When a woman walks into the oncologist’s office, she’s usually not alone. In fact, a new study finds that half of women have at least three people standing behind them, sitting next to them or waiting at home to help.

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A University of Delaware researcher recently received a grant from the National Institutes of Health to develop a new way to examine how cancer cells metastasize. Metastasis is responsible for 90 percent of cancer-related deaths.

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Dr. Amanda Paulovich of Fred Hutch will lead a multi-institution effort to develop a biological test to predict which treatments will work for patients with ovarian cancer. Photos, video available: http://www.fredhutch.org/en/news/media-relations/bios-photos/paulovich-amanda/photos-graphics-video.html

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Acupuncture, alone or with the medication clomiphene, does not appear to be effective in treating infertility in women with polycystic ovary syndrome (PCOS), according to a new international study including Penn State College of Medicine.

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The proverb, “physician heal thyself,” is probably more relevant today than it was in biblical times with the fast pace of life, the impact of multitasking and the unending bombardment of information, which have made emotional exhaustion almost certain. And this is especially true for obstetricians and gynecologists who experience professional burnout rates between 40 to 75 percent.

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This webinar will provide a forum to highlight the results of current WIC breastfeeding efforts and to discuss innovative strategies between WIC and other community agencies to promote, protect and support breastfeeding.

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A Loyola University Chicago study published this month has found an increase in the percentage of breast cancer patients who were diagnosed in early Stage 1, after the Affordable Care Act took effect. The increases in Stage 1 diagnoses were higher among African American and Latina breast cancer patients.

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Scientists from the University of Birmingham have discovered the link between increased male hormones and metabolic complications such as diabetes and fatty liver disease in patients with polycystic ovary syndrome (PCOS).

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Women who receive human papillomavirus (HPV) testing, in addition to a pap smear, receive a faster, more complete diagnosis of possible cervical precancer, according to a study of over 450,000 women by Queen Mary University of London (QMUL) and the University of New Mexico (UNM) Comprehensive Cancer Center.

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Georgia State University will host the First International Triple Negative Breast Cancer Conference from Sept. 18 to 20.

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A Texas 1115 Medicaid family planning demonstration proposal that would tie coverage to an exclusion of Planned Parenthood would severely constrain access for covered women, thereby defeating, rather than advancing, Medicaid’s core objectives.

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Johns Hopkins researchers report that a molecular diagnostic test accurately distinguishes among the three most common causes of vaginitis, an inflammation of vaginal tissue they say accounts for millions of visits to medical clinics and offices in the U.S. each year.

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As published in JNCCN, a Siteman Cancer Center study uncovered potential to significantly improve NCCN Guidelines-concordant care in patients with early-stage breast cancer.

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Erectile dysfunction drugs such as Viagra and Cialis can cause an adverse reaction during surgery or other procedures requiring anesthesia. Anesthesia and nitric oxide, the key ingredient in Viagra and Cialis should NOT EVER be mixed.

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The medical journal publishing original research in the field of obstetrics and gynecology with the highest impact factor is edited on the campus of the Wayne State University School of Medicine.

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Most UTIs are caused by E. coli that live in the gut and spread to the urinary tract. A new study from Washington University School of Medicine in St. Louis has found that a molecular decoy can reduce the numbers of UTI-causing bacteria in the gut, potentially reducing the risk of recurrent UTI.

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In a study of predominantly African-American women — who have a much higher rate of delivering babies early compared with other racial groups — researchers at Washington University School of Medicine in St. Louis showed that a decrease in the diversity of vaginal microbes of pregnant women between the first and second trimesters is associated with preterm birth.

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Research done at Argonne National Laboratory’s Advanced Photon Source was vital to the process of identifying the structure, which provides a guide for designing a Lassa virus vaccine. Lassa virus is endemic to Africa and kills thousands of people a year; it is particularly deadly for pregnant women.

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Researchers at the University of North Carolina School of Medicine announced the publication of results from a multi-site phase 2 clinical trial with brexanolone, an investigational medication, in the treatment of severe postpartum depression (PPD).

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In a study published today in Cancer Cell, Moffitt Cancer Center researchers report that a newly discovered epigenetic mechanism can lead to the development of castration-resistant prostate cancer. They identified a novel drug that targets this epigenetic mechanism and may be able to combat the deadly form of the disease.

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University of Colorado Cancer Center study pinpoints promising link in the chain of hedgehog signaling that, when broken, could reduce the metastatic potential of breast cancer.

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An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors. The findings, which researchers call a success story for genome mapping, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.

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The latest HPV vaccine could prevent most HPV infections — and millions of cancers — worldwide, according to an article by Cosette Wheeler, PhD, and her collaborators. The article describing the HPV vaccine and strategies to overcome issues with its use was published online by the American Society of Clinical Oncology.

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Grateful for the life-saving care they received at Loyola Medicine, Peter and Heidi Huizenga have made a generous gift to further oncology research and to honor Kathy Albain, MD, FACP, FASCO.

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Abortion fund recipients who have to travel out of state for an abortion travel roughly 10 times farther for their procedures than patients able to get care in their homes states.

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Most women who undergo a cesarean childbirth are prescribed more opioid (narcotic) pain medications than needed upon release from the hospital, a Vanderbilt University Medical Center (VUMC) study shows.