Feature Channels: Pharmaceuticals

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ROCHESTER, Minn. – Despite increased attention to opioid abuse, prescriptions have remained relatively unchanged for many U.S. patients, research led by Mayo Clinic finds. The research, published in The BMJ, shows that opioid prescription rates have remained flat for commercially insured patients over the past decade. Rates for some Medicare patients are leveling but remain above where they were 10 years ago.

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The University of Illinois at Chicago College of Pharmacy and the UIC/National Institutes of Health Center for Botanical Dietary Supplements Research will host an open-to-the-public garden walk and lecture to celebrate the first and only urban medicinal plant garden in Chicago.

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• When opioids are prescribed following surgery, approximately four percent of the general patient population will continue using opioids for an extended time period • Race and household income were not significant risk factors for prolonged opioid use • Physicians’ prescribing practices may influence patient risk • Patients in the worker’s compensation setting experienced the highest rates of prolonged opioid use

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Cornell University’s College of Agriculture and Life Sciences announced Aug. 1 the renaming of the New York State Agricultural Experiment Station (NYSAES) to Cornell AgriTech.

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Mount Sinai researchers have discovered that certain drug cocktails help targeted therapies attack cancer more efficiently while lessening common side effects, according to a study published today in Cancer Research.

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A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs.

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Healthcare teams in patient care settings can develop policies and procedures to minimize the impact of drug shortages by incorporating new guidelines published today by ASHP (American Society of Health-System Pharmacists). The ASHP Guidelines on Managing Drug Product Shortages provide a framework for responding to drug shortages and outline best practices to improve quality of patient care.

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Ramnath Subbaraman, a Tufts University School of Medicine assistant professor of public health and community medicine, has been selected to receive a 2018 Clinical Scientist Development Award from the Doris Duke Charitable Foundation. The award supports his research to improve tuberculosis care in India.

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Johns Hopkins Medicine researchers say their small survey of nearly 100 health care practitioners who are members of the Sexual Medicine Society of North America revealed that only half routinely ask their patients directly about their sexual orientation. In addition, the survey found, of those who do not ask, more than 40 percent say that sexual orientation is irrelevant to patients’ care, a position contrary to longstanding clinical evidence.

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"HIV/AIDS is a known killer. Today, we could wipe it off the face of the earth if we simply shared. That’s a priceless opportunity that we can’t afford … to miss." Patricia Davidson, nursing expert and dean of the Johns Hopkins School of Nursing explains why stigma, lack of awareness, and over-the-top pricing prevent people from being able to use Truvada, also known as PrEP, which is 99 percent effective at preventing HIV infection.

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Fujirebio Inc., a consolidated subsidiary of Miraca Holdings Inc., (Head office: Shinjuku-ku, Tokyo, President and CEO: Yoshihiro Ashihara, hereinafter “Fujirebio” or “the Company”) announced today that it has entered into an agreement with US-based Janssen Pharmaceuticals, Inc. (hereinafter “Janssen”) to develop and commercialize an AMYLOID β 42/40 RATIO assay.

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MedTest Holdings, the solution provider of choice offering integrated products and services for decentralized clinical diagnostic testing, today announced the debut of its new corporate name—MedTest Dx—at the upcoming 2018 American Association for Clinical Chemistry (AACC) Annual Scientific Meeting.

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Communication breakdown among nurses and doctors is one of the primary reasons for patient care mistakes in the hospital.

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Seriously, does anyone really like peas? More importantly, should parents pressure kids to eat them anyway, and does it hurt or help the child?

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In a series of experiments with mice, Johns Hopkins investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol.

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PHILADELPHIA— The United States Congressional Budget Office estimates that 5 percent of the country’s gross domestic product (GDP) is spent on medical tests and procedures that do not improve patient outcomes. In an effort to reduce unnecessary testing, procedures and related spending, the federal Centers for Medicare & Medicaid Services (CMS) has named Penn Medicine and two other organizations among a select few health care organizations in the country designated as a “qualified provider-led entity” (QPLE).

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Pairing an online patient dashboard with “nudges” to doctors tripled statin prescribing rates in a clinical trial led by Penn Medicine researchers. The study used two nudges, active choice framing to prompt physicians to make a decision on prescriptions, and peer comparison feedback which provided physicians with information on their performance relative to other physicians.

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New research by University of Utah S.J. Quinney College of Law Professor Jorge Contreras published in Science examines how sharing —and not sharing — resources in biomedical research can complicate the development of important medical advances on the 20th anniversary of the introduction of the “anticommons” theory.

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Two units of plasma given in a medical helicopter on the way to the hospital could increase the odds of traumatically injured patients with severe bleeding surviving by 10 percent, according to the results of a national clinical trial.

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On-demand (virtual) health solutions enable the patient to undergo a therapeutic process with a computer acting as a virtual clinician • The licensed clinicians supervise the process, leveraging mass data collection for clinical insights not otherwise available in a regular clinical setting • On-demand tele-therapy can be a more efficient and effective model, and directly contributes to reducing the economic burden of health

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John Wherry, PhD, has been appointed the new chair of the department of Systems Pharmacology and Translational Therapeutics at Penn. He is an international leader in the study of T cell exhaustion, which prevents optimal control of infections and can hamper anti-tumor immune responses.

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Assistant Professor Jungkyu (Jay) Kim microengineered a chip that replicates the human cornea and can be used to help speed up the drug-evaluation process for eye medications.

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The Accreditation Council for Pharmacy Education (ACPE) has elevated The University of Texas at El Paso's School of Pharmacy to "candidate" status, taking the school one step closer to earning full accreditation in 2021. Candidate status provides graduates from UTEP’s Doctor of Pharmacy (Pharm.D.) program the same rights and privileges that they would have from a fully accredited pharmacy program. Graduates will be able to take the North American Pharmacist Licensure Examination (NAPLEX) to become licensed to practice in any state in the United States.

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Published in Addiction, a new paper lays out some of the factors that lead policymakers to look for easy answers to complex problems related to opioid addiction.

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Patients who sought care for a sprained ankle in states that were found to be "high prescribers" of opioids were approximately three times more likely to receive a prescription for the drugs than those treated in "low-prescribing" states, according to new research. Additional results of the study show that patients who received prescriptions for long courses of the drugs (e.g. more than 30 tablets of oxycodone 5 mg) were five times more likely to fill additional opioid prescriptions over the next 6 months than those who received just a few days' supply (e.g. 10 tablets of less).

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Researchers at the RIKEN Center for Integrative Medical Science in Japan have discovered how antibodies secreted in the gut promote the growth of beneficial bacteria. Their study, which will be published July 24 in the Journal of Experimental Medicine, shows that immunoglobulin A (IgA) antibodies can alter the expression of bacterial genes, allowing different bacterial species to cooperate with each other and form a community that can protect the body from disease.

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A team of researchers recently discovered a new aspirin polymorph that’s predicted to dissolve faster than current form I aspirin tablets, which would mean faster pain relief after ingestion. Greater dissolving efficiency also means that each tablet would require less of the compound. Chunhua (Tony) Hu, New York University, will present the painstaking story of aspirin IV alongside its structural definition at the 68th Annual Meeting of the American Crystallographic Association.

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A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.

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Technologies that are reducing costs and changing the ways in which researchers and clinicians process and use therapeutic cells are showcased in the August 2018 special issue of SLAS Technology.

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A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

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Chicago’s only hospital-based medical flight program began flying a more advanced helicopter this month, an Airbus EC145.

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En los adultos de más de 70 años, la exposición a la anestesia general y a una cirugía se relaciona con un ligero deterioro de la memoria y de las capacidades de pensamiento, dice un nuevo estudio de Mayo Clinic.

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The PhRMA Foundation has released its 2017 Annual Report, highlighting the work of its grant awardees and progress on other initiatives and projects. The Foundation awarded more than $3 million last year in funding to support the research projects of early career scientists and to advance important health care initiatives, including improving value in health care. The Foundation provided more than 40 awards, grants and fellowships.

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The study compared the performance of weekly and monthly CAM2038, with the current standard of care, a daily sublingual dose of buprenorphine/naloxone. Results showed the drug’s non-inferiority on the primary responder rate outcome, which was based upon highly sensitive urine testing detecting illicit opioids. The data suggests that injectable buprenorphine is efficacious and may have advantages.

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This summer, UTEP School of Pharmacy students have been visiting recovering women addicts at a treatment center in Nashville, Tennessee, or standing on the Cliffs of Moher on the western coast of Ireland. Since March, dozens of students from the Doctor of Pharmacy program’s inaugural class at The University of Texas at El Paso have traveled across the country and overseas to engage in unique learning experiences designed to prepare future pharmacists to better serve diverse communities and cultures.

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Two dozen distinguished individuals and one corporate partner will be honored by the UWM Alumni Association on Oct. 12, 2018. The eclectic, inspiring and accomplished list of awardees is now available.

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UK researcher Don Helme is partnering with the Kentucky Attorney General’s office to gauge public opinion on a new drug deactivation pouch, part of a larger effort to develop solutions to the state’s opioid epidemic. Four counties have received Deterra, the deactivation pouch.

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Contrary to popular belief across college campuses, attention deficit hyperactivity disorder (ADHD) medications may fail to improve cognition in healthy students and actually can impair functioning, according to a study by researchers at the University of Rhode Island and Brown University.

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With more than $2 million from the National Institute of Neurological Disorders and Stroke, a team at GW led by Chiara Manzini, PhD, will study the CC2D1A gene and its role in the development of autism in males versus females.

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Roy Ervin Twyman, MD, PhD, an academic neurologist with nearly 20 years’ experience in neuroscience pharmaceutical drug development, will join the NeuroVision Imaging Inc. Board of Directors on July 20.

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NYU Langone study serves as an important reminder of how stressful pregnancy can be on the female body and heart, causing a lot of physiological changes, and potentially unmasking risk factors that can lead to heart attack.

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David Coy, MD, PhD, has been named chief of radiology at Virginia Mason to succeed Lucy Glenn, MD, who recently retired.

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Designation from the National Cancer Institute denotes the highest level of scientific excellence.

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PHILADELPHIA – Penn Wissahickon Hospice and Caring Way received the Circle of Life® award from the American Hospital Association (AHA) for expanding the reach of innovative palliative and end-of-life care to the community. Penn was among three programs nationwide to receive this honor, along with Arizona Palliative Home Care Program and Palliative Care and Western Connecticut Health.

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Southern Research announced today that accomplished researcher Dr. Babu L. Tekwani has joined the Birmingham-based organization as Distinguished Fellow and Chair of the Infectious Disease Department in Drug Discovery.

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A new study in which Lawrence Livermore National Laboratory scientists compared drug responses in the brains of rodents to drug responses of brain cells cultured in Lab-developed “brain-on-a-chip” devices may be a critical first step to validating chip-based brain platforms, LLNL researchers said.

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According to Clarivate Analytics’ Journal Citation Reports, the 2017 impact factors for AAPS’ journals were all highly ranked in the category of Pharmacology and Pharmacy.