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Women's Health, Aging, Cellular Aging, Exercise, Epidemiology, geriatric research, Sedentary Lifestyles

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 18-Jan-2017 3:00 PM EST

Medicine

Science

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Monkeys, Rhesus Monkeys, Calories, Diet, Longevity, Aging

Calorie Restriction Lets Monkeys Live Long and Prosper

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Settling a persistent scientific controversy, a long-awaited report shows that restricting calories does indeed help rhesus monkeys live longer, healthier lives. A remarkable collaboration between two competing research teams — one from the University of Wisconsin-Madison and one from the National Institute on Aging — is the first time the groups worked together to resolve one of the most controversial stories in aging research.

Medicine

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Shark, Parkinson's Disease, Steroid, Protein, Nervous System, Lewy Body Dementia

Steroid Originally Discovered in the Dogfish Shark Attacks Parkinson’s-Related Toxin in Animal Model

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A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease. The clustering of this protein, alpha-synuclein (α-synuclein), is the hallmark of Parkinson’s and dementia with Lewy bodies, suggesting a new potential compound for therapeutic research.

Medicine

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Medicaid, Affordable Care Act , medicaid expansion, Economic Impact, Health Insurance

Medicaid Expansion Boosts Michigan’s Economy and Will More Than Pay for Itself

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Michigan’s Medicaid expansion has boosted the state’s economy and budget, and will continue to do so for at least the next five years, a new study finds.

Medicine

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Cancer, Cancer Research, Ut Southwestern

Researchers Uncover Mechanism for Cancer-Killing Properties of Pepper Plant

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– UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years.

Medicine

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St. Jude Children's Research Hospital, Infection, Antibiotic, Antibiotic Resistance, Immune System, VRE, blood stream infection, bacterial biofilm, Biofilm, Enterococcus faecium

Infant’s Prolonged Infection Reveals Mutation That Helps Bacteria Tolerate Antibiotics

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A life-threatening infection in an infant with leukemia led to a St. Jude Children’s Research Hospital discovery of how prolonged infection sets the stage for bacterial persistence despite antibiotic susceptibility.

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Seth Blackshaw, Brain, Suprachiasmatic Nucleus, ScN, Fever, Jet Lag, Temperature

Here's Why You Don't Feel Jet-Lagged When You Run a Fever

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A clump of just a few thousand brain cells, no bigger than a mustard seed, controls the daily ebb and flow of most bodily processes in mammals -- sleep/wake cycles, most notably. Now, Johns Hopkins scientists report direct evidence in mice for how those cell clusters control sleep and relay light cues about night and day throughout the body.

Medicine

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Sunlight, Sunlight Exposure, T Cells, Infection, Vitamin D, Hydrogen Peroxide

Sunlight Offers Surprise Benefit — It Energizes Infection Fighting T Cells

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Researchers have found that sunlight, through a mechanism separate than vitamin D production, energizes T cells that play a central role in human immunity. The findings suggest how the skin, the body’s largest organ, stays alert to the many microbes that can nest there.

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Travel, toddler injuries, Car Seat Safety, family vacation, Holiday Travel, children and travel

Poll: Some Parents Forgo Car Seats, Other Safety Measures While Traveling

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But what some parents may not plan for ahead of vacation: accidental poisoning risks, gun safety and Uber rides.

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Protein in Urine Linked to Increased Risk of Memory Problems, Dementia

People who have protein in their urine, which is a sign of kidney problems, may also be more likely to later develop problems with thinking and memory skills or even dementia, according to a meta-analysis published in the December 14, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Medicine

Science

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Kansas State University, KSU, K-State, Edgar Chambers, Edgar Chambers IV, Food Safety, Celebrity Chefs, Cooking show

Celebrity Chefs Have Poor Food Safety Practices

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Celebrity chefs are cooking up poor food safety habits, according to a Kansas State University study. Kansas State University food safety experts Edgar Chambers IV and Curtis Maughan, along with Tennessee State University's Sandria Godwin, recently published "Food safety behaviors observed in celebrity chefs across a variety of programs" in the Journal of Public Health.

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Pediatric Cancer, Cancer, personalized medicine, digital health, Oral Health, UCLA, UCLA School of Dentistry, Artificial Intelligence, drug, drug dosing, Drug Therapy

‘Turbocharged Artificial Intelligence’ Could Personalize Combination Therapy in Pediatric Leukemia

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UCLA researchers show the potential of their digital health platform to help treat acute lymphoblastic leukemia by being able to personalize drug dosages and combinations

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'Rewired' Cells Show Promise for Targeted Cancer Therapy

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A major challenge in truly targeted cancer therapy is cancer’s suppression of the immune system. Northwestern University synthetic biologists now have developed a general method for “rewiring” immune cells to flip this action around. When cancer is present, molecules secreted at tumor sites render many immune cells inactive. The Northwestern researchers genetically engineered human immune cells to sense the tumor-derived molecules in the immediate environment and to respond by becoming more active, not less.

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Canner, Suicide, Emergency, Injury

Attempted Suicide Rates and Risk Groups Essentially Unchanged, New Study Shows

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Johns Hopkins investigators report that their analysis of a national database representing more than 1 billion emergency department visits shows that over a recent eight-year period, nothing much has changed in the rates of unsuccessful suicide attempts, or in the age, gender, seasonal timing or means used by those who tried to take their lives in the United States.

Medicine

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Roland Griffiths, Cancer, Drugs, Anxiety, Psilocybin

Hallucinogenic Drug Psilocybin Eases Existential Anxiety in People with Life-Threatening Cancer

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In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushrooms."

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Parkinson's Disease, Gene Mutation

Gene Mutation Linked to Early Onset of Parkinson’s Disease in Caucasians

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A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson’s disease, according to new research from Iowa State University. The effect is particularly dramatic for young-to-middle-age adults.

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Breastfeeding, Womens Health, Maternal And Child Health, disparities in healthcare, Minority Health, Access To Care

Study Shows Alarming Disparities in Health Outcomes Could Be Prevented by Breastfeeding

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Lack of paid leave and outdated maternity care are barriers to breastfeeding that disproportionately impact families of color. This is the first study to show how these disparities translate into differences in health outcomes.

Medicine

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Alzheimers disease, Dementia, Alzheimer's, Amyloid, Neuroscience, Biochemistry, brain blood vessel, Cognitive Impairment

Unique Structure of Brain Blood Vessel Amyloid Latest Clue to Alzheimer’s Development?

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A team of neuroscience and biochemistry researchers at Stony Brook University have made a novel discovery that illustrates for the first time the difference between amyloid buildup in brain blood vessels and amyloid buildup around brain neurons.

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Reflux and Ulcer Medications Linked to Kidney Stones and Chronic Kidney Disease

• Individuals who took proton pump inhibitors or histamine receptor-2 blockers for heartburn, acid reflux, or ulcers had elevated risks of developing kidney stones. • In individuals without acute kidney injury, proton pump inhibitors were linked with a higher risk of developing chronic kidney disease or kidney failure compared with histamine receptor-2 blockers. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

Medicine

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Pregnancy and Childbirth, Longevity, Aging, Gerontology, advanced maternal age, OB GYN

Older First-Time Mothers Are Also More Likely to Live Longer

The average age of a woman giving birth for the first time has risen dramatically in the United States over the past 40 years, driven by factors like education or career. A new study by researchers at University of California San Diego School of Medicine found that women choosing to become first-time mothers later in life may increase their chances of living into their 90s.







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