A study led by physicians at the University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego looked at intensification of initial therapy for all children with Kawasaki Disease in order to prevent IVIG-resistance and associated coronary artery abnormalities by assessing the addition of the medication infliximab to current standard therapy.
With one heartbeat, within one second, cardiologists can get an entire 3-D image of the heart that allows them to look at arteries and heart anatomy with excellent detail and with less medical radiation.
A team of researchers at the University of Florence in Italy and the University of Connecticut Health Center have used a multidisciplinary approach to provide an unprecedented glimpse of what happens to the heart during an "infarction" -- a heart attack -- by looking at how the attack affects electrical activity and calcium release in heart cells.
In a Perspective column today in the New England Journal of Medicine, Penn Medicine cardiologist and Robert Wood Johnson Foundation Clinical Scholar Lisa Rosenbaum, MD, discusses barriers to helping women understand their heart health risks.
More people who have known coronary heart disease die from other causes — such as cancer, and lung and neurological diseases — than heart disease, compared with 20 years ago, according to a Mayo Clinic study published online today in Circulation, an American Heart Association journal.
New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type. The findings may guide the search for improved treatments.
Despite the fact that heart disease is the leading cause of death for both men and women in the U.S., about three-quarters (74 percent) of Americans do not fear dying from it, according to a recent survey from Cleveland Clinic.
Getting too much added sugar in your diet could significantly increase your risk of dying from cardiovascular disease, according to a study published Monday. Sugar-sweetened beverages are the largest source of added sugars in the American diet.
February is American Heart Month reminding all Americans that promotion of heart health is the most critical prevention tool we have available today. Dr. Valentin Fuster shares his top three prevention tips for adults and children.
Pass codes, phone numbers and addresses. We all have a lot of numbers in our heads, but heart experts at The Ohio State University Wexner Medical Center say there are 5 more you need to know to help keep your heart healthy.
A strong sensation of pressure—what some have described as an elephant sitting on one’s chest—can be one of the red flags that someone is experiencing a heart attack and should seek immediate medical assistance. But if you are a woman, waiting to feel this type of pain may be a mistake. Fifty percent of the time a woman has a heart attack, there will be no chest pain involved, explains Dr. Liliana Cohen, a board-certified cardiologist with Rutgers Robert Wood Johnson Medical Group.
Heart transplantation continues to be the “gold standard” treatment for end-stage heart failure, and a large number of patients now live 20 years or more after surgery
Detailed prediction models that project long-term patient mortality following PCI and CABG surgery can be useful for the heart team when determining the best treatment strategy for individual patients
A new device tested first at the University of Michigan may provide a minimally invasive option for the elderly who are facing life-threatening thoracic aneurysms.
A study led by researchers at the University of California, San Diego School of Medicine shows that one of the most widely used systems for predicting risk of adverse heart events should be re-evaluated. A surprise finding was that coronary artery calcium (CAC) density may be protective against cardiovascular events. The study of CAC will be published in the January 15 issue of the Journal of the American Medical Association.
A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.
The symptoms of heart disease are often less obvious in women than in men, and as a result, some experts have recommended changing current medical practice and using separate criteria to identify the disease and predict its progression in women. However, new findings in the “Advancing Women’s Health” issue of Clinical Chemistry, the journal of AACC, suggest that sex-specific criteria do not improve the prognostic accuracy of blood tests for diagnosing heart disease.
Doctors may need to treat high blood pressure in women earlier and more aggressively than they do in men, according to scientists at Wake Forest Baptist Medical Center.
Gurusher Panjrath, M.D., assistant professor of medicine and director of the Heart Failure and Mechanical Support Program at the George Washington University School of Medicine and Health Sciences, was recently published in the journal Science Translational Medicine for his study, "Metabolic Rates of ATP Transfer Through Creatine Kinase (CK Flux) Predict Clinical Heart Failure Events and Death."
For patients with stable coronary artery disease (CAD) who are not experiencing a heart attack and an abnormal stress test, treatment of their narrowed arteries by the common procedure of angioplasty may not provide additional benefits compared to drug therapy alone. This finding results from a survey of more than 4,000 patients with myocardial ischemia, or inadequate circulation, led by cardiologists at Stony Brook University School of Medicine. The survey results are published in the online first edition of JAMA Internal Medicine.
For many households of Mexican descent in the United States, the days following Thanksgiving aren’t only about wrapping gifts but also about wrapping tamales.
Johns Hopkins researchers have developed a more accurate way to calculate low-density lipoprotein (LDL) cholesterol, the so-called “bad” form of blood fat that can lead to hardening of the arteries and increase the risk of heart attack and stroke. If confirmed and adopted by medical laboratories that routinely calculate blood cholesterol for patients, the researchers say their formula would give patients and their doctors a much more accurate assessment of LDL cholesterol.
Researchers from the Intermountain Medical Center Heart Institute, in collaboration with researchers from Johns Hopkins University and the National Institutes of Health, have discovered a simple way to further predict a diabetic patient’s risk for heart disease: by measuring their body mass index or BMI.
A new study highlights the importance of exercise and physical fitness among people with stable coronary artery disease. Researchers at the Johns Hopkins University School of Medicine and Henry Ford Hospital found that higher levels of physical fitness lower the risk of having heart attacks and increase survival in those with coronary artery disease, whether or not they have had a procedure to open up their blocked arteries.
The reality of existing insurance coverage precludes effective implementation of four newly released cardiovascular guidelines from the American Heart Association and American College of Cardiology, according to the Academy of Nutrition and Dietetics. The Academy supports the new guidelines and urges public and private insurance carriers to follow the recommendations so that Americans will have access to health care they deserve.
Researchers at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai have successfully tested a powerful gene therapy, delivered directly into the heart, to reverse heart failure in large animal models.
Patients with rheumatoid arthritis, lupus and other chronic forms of inflammatory arthritis can face life-threatening complications, and heart disease tops the list. People with such rheumatic diseases are twice as likely as the average person to develop heart problems.
A minimally invasive procedure is the first effective treatment for patients who are high risk for standard open heart surgery for a leaking heart valve, a study led by a University of Virginia School of Medicine researcher has found.
New research from the Cleveland Clinic shows most patients with diabetes and obesity who undergo gastric bypass not only experience remission of their diabetes and lose significant weight, but they also reduce their risk of having a heart attack by 40 percent and their risk for suffering a stroke by 42 percent, over a 10-year time horizon.
Researchers find a genetic difference in blood clotting mechanisms, which could help explain some of the racial health disparity in heart disease.
Some vegetable oils that claim to be healthy may actually increase the risk of heart disease, and Health Canada should reconsider cholesterol-lowering claims on food labelling, states an analysis in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.130253.
• In patients with chronic kidney disease who lowered their salt intake for two weeks, excess extracellular fluid volume, blood pressure, and protein excretion in the urine all dropped considerably. • If maintained long-term, the effects could reduce a patient’s risk of progressing to kidney failure by 30%.
Current medical guidelines use a one-size-fits-all treatment approach that leads to some patients being on too many medications and others being on too little.
Results of a Johns Hopkins study published today in the journal Diabetes Care found that young and middle-aged women with type 2 diabetes are at much greater risk of coronary artery disease than previously believed.
Among patients with early stages of breast cancer, those whose hearts were more directly irradiated with radiation treatments on the left side in a facing-up position had higher risk of heart disease, according to research letter by David J. Brenner, Ph.D, D.Sc, of Columbia University Medical Center, New York, and colleagues.
Body temperature follows a 24-hour rhythm, peaking during the day, low at night. The benefit might be the conservation of energy while sleeping. It is also critical to be able to adapt to changes in ambient temperature regardless of the time of day. A new mouse study shows how body temperature rhythms are synchronized while maintaining the ability to adapt to changes in environmental temperature day or night.
People with rheumatoid arthritis and other chronic inflammatory conditions are at higher risk of heart disease. Who is in the most danger, why and how best to prevent and detect cardiovascular complications are important questions for physicians and researchers.
Obstructive sleep apnea is known to be associated with an increased incidence of cardiovascular disease. Now a new study indicates that OSA is associated with subclinical myocardial injury, as indicated by increased high sensitivity troponin T (hs-TnT) levels. Elevated hs-TnT levels are predictive of both coronary heart disease (CHD) and heart failure (HF) in the general population. This is the first study to demonstrate an independent association between sleep apnea severity and this marker of early myocardial injury.
There is an association between the influenza virus and cardiovascular events like heart disease and stroke; those with cardiovascular disease should protect themselves against the flu.
Researchers at the University of Illinois at Chicago have identified a protein expressed by human bone marrow stem cells that guides and stimulates the formation of blood vessels. Their findings, which could help improve the vascularization of engineered tissues, were reported online on October 12 in the Journal of Molecular and Cellular Cardiology.
The incidence of chronic pain following cardiac surgery can be reduced in patients when the drug pregabalin is used before surgery and for 14 days post-surgery, according to a study presented at the ANESTHESIOLOGY™ 2013 annual meeting. The study also found that patients at risk of developing long-term post-operative persistent pain can be predicted by conducting pain sensitivity tests at the time of surgery.
Long-term memory loss, difficulty understanding verbal or written communication or impaired ability to pay attention may still occur five years after heart surgery if a patient has a certain gene variation, according to a study presented at the ANESTHESIOLOGY™ 2013 annual meeting. This gene was found to be related to a decline in cognitive capabilities compared to those who do not have the variation.
University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy.
A global hunt for genes that influence heart disease risk has uncovered 157 changes in human DNA that alter the levels of cholesterol and other blood fats – a discovery that could lead to new medications.
Mitochondria are the power plants of cells, manufacturing fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in cell suicide. Now, researchers at Washington University School of Medicine in St. Louis and the University of Padua-Dulbecco Telethon Institute in Italy have shown that mitochondria remarkably also orchestrate events that determine a cell’s future, at least in the embryonic mouse heart. The new study identifies new potential genetic culprits in the origins of some congenital heart defects.
Johns Hopkins University School of Nursing joins worldwide effort to increase awareness and seek a cure for cardiovascular disease.
Genes in mitochondria, the “powerhouses” that turn sugar into energy in human cells, shape each person’s risk for heart disease and diabetes.
A biological ability to compensate for the body’s reduced response to insulin may explain why women typically develop heart disease 10 years later than men, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
University at Buffalo translational researchers are developing a richer understanding of atherosclerosis in humans, revealing a key role for stem cells that promote inflammation.
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