Wolters Kluwer, a leading global provider of information and point of care solutions for the healthcare industry, and the European Hematology Association (EHA) are pleased to announce the launch a new open access journal, HemaSphere. Part of the Lippincott portfolio, the journal was launched today at the 22nd Annual Congress of the European Hematology Association in Madrid.
HIV-positive women with CMV in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV to their infants. The research also found that they are nearly 30 times likelier to transmit CMV to their infants.
A simple blood test could improve treatment for more than 1 in 6 stage 2 colon cancer patients, suggests new Mayo Clinic research. The researchers also discovered that many patients who could benefit from the test likely aren’t receiving it. The findings were published in the Journal of Gastrointestinal Surgery.
Today, a team of investigators at Children’s Hospital Los Angeles launched OncoKidsSM, a next-generation sequencing-based panel specifically designed for pediatric cancers.
Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leukemias and solid tumors. The findings open possibilities for new clinical approaches.
A new, minimally invasive system which uses radiofrequency energy instead of open surgery to create access for patients needing hemodialysis, is reliable, with minimal complications, according to data published in the American Journal of Kidney Diseases.
At a glance: People with low levels of vitamin A living in households with people who have TB were 10 times more likely to develop the disease themselves. The study findings suggest that vitamin A supplementation may offer powerful protection against the deadly disease among high-risk individuals. TB, one of the top infectious disease killers globally, hits especially hard in low- and middle-income countries, where vitamin A deficiencies are common.
Studying mice, researchers at Washington University School of Medicine in St. Louis have shown that a natural sugar called trehalose revs up the immune system’s cellular housekeeping abilities. These souped-up housecleaners then are able to reduce atherosclerotic plaque that has built up inside arteries. Such plaques are a hallmark of cardiovascular disease and lead to an increased risk of heart attack.
Rush University Medical Center is offering a new, implantable cardiac device to reduce the risk of stroke in patients with atrial fibrillation, providing an alternative to the long-term use of blood thinners.
Memory loss, language problems and other symptoms of cognitive decline are strongly associated with diseases of the small blood vessels in the brain, according to a study published in the International Journal of Geriatric Psychiatry.
A new study conducted by researchers from Tulane University finds reducing target systolic blood pressure below current recommendations significantly reduces the risk of cardiovascular disease and preventable death.
It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications.
A research team from the National University of Singapore led by Assistant Professor Takaomi Sanda, Principal Investigator from the Cancer Science Institute of Singapore and Department of Medicine at NUS Yong Loo Lin School of Medicine, has provided new insights into the molecular mechanism affecting how genes are produced during normal T-cell development, and contributing to leukaemia formation.
Blood thinners, such as aspirin, reduce the risk of thrombus formation but also interfere with the initial clot formation that is essential for preventing blood loss from the wounds. Now researchers have discovered that a molecule plays a role in thrombus development, but not the initial clot formation, suggesting a new avenue for developing more specific and protective blood thinners.
The University of Kansas Cancer Center joins Blood Cancer Research Partnership
Garret FitzGerald, MD, FRS, director of the Institute for Translational Medicine and Therapeutics in the Perelman School of Medicine at the University of Pennsylvania, has received a $1 million Merit Award from the American Heart Association (AHA) to help the millions of patients with high blood pressure improve their condition.
Coronary artery disease (CAD) is a leading cause of death worldwide. Despite dozens of regions in the genome associated with CAD, most of the genetic components of heart diseases are not fully understood, suggesting that more genes are out there to be found. A team found 15 new risk genes for coronary artery disease.
Brian Samuels, M.D., says there is an increase of eye pressure throughout the morning, and that pressure comes and goes throughout the day. This fluctuation is a known risk factor for the progression of glaucoma.
A new discovery may be the key to stopping shortages of vital blood-clotting cells that can represent the difference between life and death. The finding also could offer big benefits for premature babies.
One in three patients hospitalized for medical problems experienced a drop in their red blood cell count due to the hospitalization – a concept called hospital-acquired anemia, new research showed.
Research findings to be published about new blood test technology that will greatly reduce errors in labwork and improve care in public health and infectious disease. Press briefing scheduled for May 16, reserve press access to live virtual event now.
A study at the University of Nebraska Medical Center (UNMC) found that a novel device can significantly reduce contamination of blood cultures, potentially reducing risky overtreatment and unnecessary use of antibiotics for many patients. This approach could also substantially reduce healthcare costs, according to the study. Thousands of U.S. patients get their blood drawn every day for blood cultures in order to diagnose serious infections such as sepsis, which can be a deadly condition. A small but significant percentage of the blood cultures are contaminated, due in part to skin fragments containing bacteria that are dislodged during a blood draw. This leads to false results that can mislead clinicians into thinking a patient has a potentially serious bloodstream infection. The consequences are costly and put patients at risk.
In a virtual media briefing next Tuesday, May 16, at 11:30 a.m. EDT, noted infectious disease expert Mark Rupp, M.D. will detail the results of a forthcoming journal publication on a new device.
Some of the world's leading experts in the field of autoimmune vasculitis research will present at the 2017 International Vasculitis Symposium in Chicago. Sessions will include information about the latest vasculitis research, and treatment and management of autoimmune vasculitis.
Hundreds of thousands of children with chronic illnesses who used to die are now surviving their disease and treatment—which is amazing. But their brains are being damaged in the process of keeping them alive. This first ever research quantifies the IQ impact of six main illnesses and looks and the common threads that connect them. It also takes next steps on how psychologists can team up with surgeons/oncologists, etc. to help treat kids and their parents, so they can thrive in school and life.
A new study finds that dietary nitrate—a compound that dilates blood vessels to decrease blood pressure—may reduce overstimulation of the sympathetic nervous system that occurs with heart disease. The research team looked specifically at beetroot juice, a source of dietary nitrate, to explore its use as a future targeted treatment option for people with cardiovascular disease.
UT Southwestern research investigating the blood glucose-regulatory actions of the hormone ghrelin may have implications for development of new treatments for diabetes.
An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, “Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome,” which will be published May 9 in The Journal of Experimental Medicine, shows that synthetic versions of this microRNA can reduce intestinal inflammation in mice and suggests a new therapeutic approach to treating patients with Crohn’s disease or ulcerative colitis.
Researchers have developed a new technique that uses modified insulin and red blood cells to create a glucose-responsive “smart” insulin delivery system. In an animal model study, the new technique effectively reduced blood sugar levels for 48 hours in a strain of mice that had Type 1 diabetes.
A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.
At a glance: · New study reveals that blood-brain barrier function relies on the balance between omega-3 fatty acids and other lipids in cells that line blood vessels in the central nervous system. · This lipid make-up keeps the barrier closed by inhibiting the formation of vesicles that shuttle molecules across cells, a process known as transcytosis. · Low levels of vesicles are maintained by the lipid transport protein Mfsd2a. · Disrupting Mfsd2a may be a strategy for opening the blood-brain barrier to deliver drugs into the brain.
New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.
A pilot study among young children with Type 1 diabetes found that a University of Virginia-developed artificial pancreas helped study participants better control their condition.
A new study that followed more than 2,600 men and women for 16 years found that consuming less sodium wasn’t associated with lower blood pressure. The study adds to growing evidence that current recommendations for sodium intake may be misguided.
Winner of the DePuy Synthes Cerebrovascular Award, Fawaz Al-Mufti, MD, presented his research, White Blood Cell Count and Neutrophil‑lymphocyte Ratio Improve Prediction of Delayed Cerebral Ischemia in Good‑grade Subarachnoid Hemorrhage, during the 2017 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
Professor Klaus Ley, M.D., has been selected as this year’s winner of the Eugene M. Landis Award, the Microcirculatory Society’s top honor, in recognition of his pioneering work in vascular biology and microcirculation. The microcirculation comprises all the small blood vessels in all tissues and organs and their contents (blood plasma and blood cells).
In a new study presented today at the APS annual meeting at Experimental Biology 2017, researchers have found that the immune system’s natural killer (NK) cells activate and change in response to placental ischemia. Disrupting these altered cells seems to blunt some of the dangerous complications of the condition, including high blood pressure (hypertension) and inflammation in the mother and growth restriction in the fetus.
New discoveries tied to how food affects our body and why we make certain food choices could help inform nutrition plans and policies that encourage healthy food choices. The Experimental Biology 2017 meeting will showcase groundbreaking research in food policy, nutrition and the biochemistry of food.
Researchers have developed a sensor-filled glove that doctors could wear to accurately measure muscle stiffness, known as spasticity, in patients suffering from stroke, cerebral palsy, multiple sclerosis and other muscle control disorders.
An international team of collaborators retroactively examined the associations between survival among patients diagnosed with invasive epithelial ovarian cancer and those patients’ history of hypertension, heart disease, diabetes, and medications taken for those conditions. They found that while hypertension was linked to better outcomes, diabetes was associated with decreased survival.
A new, first-of-its-kind app is now available to support clinicians with decisions on best practice rehabilitation strategies for patients with arm impairment due to stroke.
The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.
Infection with reovirus, a common but otherwise harmless virus, can trigger the immune system response to gluten that leads to celiac disease, according to new research from the University of Chicago and the University of Pittsburgh School of Medicine.
Ted Rogers Centre for Heart Research study is first to show TNF operating beyond immune system, Caution needed when administering anti-TNF medications
Many hypertension medications currently on the market target the AT1 receptor because of its well-understood role in blood pressure regulation; they block AT1 in order to reduce blood pressure. The AT2 receptor, on the other hand, is still an elusive drug target despite multiple studies of its function. Now, researchers have solved its structure to hone in on its function. The results of the experiments were surprising in several ways. First, although both compounds were designed to block and deactivate the receptors, they left AT2 in a state that appeared to be active. In addition, although AT1 and AT2 were thought to be very similar, the pockets where the receptors bind to the compounds exhibited marked differences.
A new study from the Keck School of Medicine of USC links increased dietary potassium with lower blood pressure.
PinnacleHealth CardioVascular Institute enrolled the first patient in the United States in a trial assessing the safety and effectiveness of a new type of approach for blockages in the leg artery. DISRUPT PAD III is the largest ever multi-center randomized study to exclusively enroll patients with calcified peripheral artery disease (PAD).
An artificial pancreas, which delivers insulin in an automated way to individuals with type 1 diabetes, appears to be safe and effective for use in children ages 5 to 8 years, a new study finds. Results will be presented Tuesday at the Endocrine Society’s 99th annual meeting in Orlando, Fla.
Five simple medical tests together provide a broader and more accurate assessment of heart-disease risk than currently used methods, cardiologists at UT Southwestern Medical Center found.
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