Heart patients with irrational health beliefs - such as doubting the preventive value of a flu vaccine - are more likely to skip cardiac rehab sessions, new research suggests.
A new study from UAB highlights why fibrotic diseases — diseases that feature fibrosis or scarring of organ tissue — are typically associated with aging. Fibrosis, the formation of fibrous scar tissue in response to injury, is part of the normal healing process. In young animals or people, scars resolve or fade away over time and are replaced by newly grown healthy tissue. In older subjects, the scars do not resolve or fade, and scar tissue can build up. In organs such as the heart, lungs, kidneys or liver, the buildup of scar tissue can interfere with normal function, with potentially devastating results. In findings published in Science Translational Medicine, the UAB team describes the mechanism that contributes to persistent fibrosis in the aged, and suggests targets that may help reverse the buildup of scar tissue.
Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.
Three neuroscientists discuss the emerging consensus on age-related memory loss and what researchers hope to learn in coming years.
New research by Canadian sports medicine physician Mark Tarnopolsky, MD, PhD, suggests that a person can slow the speed at which they age by exercising regularly.
Study suggests people are less timid about broaching end-of-life planning and talking about death.
The latest results from a 25-year study of diet and aging in monkeys shows a significant reduction in mortality and in age-associated diseases among those with calorie-restricted diets. The study, begun at the University of Wisconsin-Madison in 1989, is one of two ongoing, long-term U.S. efforts to examine the effects of a reduced-calorie diet on nonhuman primates.
Physicians have long suspected that chemotherapy can accelerate the aging process in patients treated for cancer. Using a test developed at UNC Lineberger Comprehensive Cancer Center to determine molecular aging, UNC oncologists have directly measured the impact of anti-cancer chemotherapy drugs on biological aging.
People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as age 40 to 64 and old age as age 65 and older.
New research suggests that the more muscle mass older Americans have, the less likely they are to die prematurely. The findings add to the growing evidence that overall body composition — and not the widely used body mass index, or BMI — is a better predictor of all-cause mortality.
Study with mice shows moderate exercise can activate Nrf2, leading to stem cell regeneration.
A new study suggests that Alzheimer’s disease may contribute to close to as many deaths in the United States as heart disease or cancer. The research is published in the March 5, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Older individuals who are vitamin D deficient also tend to have compromised immune function, according to new research accepted for publication in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
When older individuals’ thyroid glands are more active than average, it may be a risk factor for depression, according to new research accepted for publication in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Lower morning and higher evening cortisol levels contribute to frailty in older individuals, according to new research accepted for publication in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Pathways of aging and sleep intersect at the circuitry of a cellular stress response pathway, and that by tinkering with those connections, it may be possible to alter sleep patterns in the aged for the better – at least in fruit flies.
By the time most people are 25, they have made the most important memories of their lives, according to new research from the University of New Hampshire.
Feeling extreme loneliness can increase an older person’s chances of premature death by 14 percent, according to research by John Cacioppo, professor of psychology at the University of Chicago.
Baby boomers can learn how to protect their hard-earned assets and guarantee a steady income for the rest of their lives through a new book by Lewis Mandell, PhD, professor emeritus in the University at Buffalo School of Management.
The accumulation of age-associated changes in a biochemical process that helps control genes may be responsible for some of the increased risk of cancer seen in older people, according to a National Institutes of Health study.
A chemical that's found in fruits and vegetables from strawberries to cucumbers appears to stop memory loss that accompanies Alzheimer's disease in mice, scientists at the Salk Institute for Biological Studies have discovered. In experiments on mice that normally develop Alzheimer's symptoms less than a year after birth, a daily dose of the compound----a flavonol called fisetin----prevented the progressive memory and learning impairments. The drug, however, did not alter the formation of amyloid plaques in the brain, accumulations of proteins which are commonly blamed for Alzheimer's disease. The new finding suggests a way to treat Alzheimer's symptoms independently of targeting amyloid plaques.
The ultraviolet radiation (UVR) present in sunlight is the most common environmental carcinogen. To develop better methods of protection from the sun, we need to understand how the human skin detects and responds to UVR. Researchers provide new insight into the molecular pathway underlying this process.
Researchers at UAB say that high-intensity strength training produced significant improvements in quality of life, mood and motor function in older patients with Parkinson’s disease. The findings were published Jan. 9 online in the Journal of Applied Physiology.
A new study from the Florida campus of The Scripps Research Institute offers insights into how aging affects the brain’s neural circuitry, in some cases significantly altering gene expression in single neurons.
Nearly half of hospitalized American adults age 65 and older require decision-making assistance from family members or other surrogates because the patient is too impaired to make decisions independently, according to a new study from the Regenstrief Institute and the Indiana University Center for Aging Research.
Older women who spend a majority of their day sitting or lying down are at increased risk for cardiovascular disease, coronary heart disease, cancer and death, finds a new study from the American Journal of Preventive Medicine.
Aging gracefully may not be an option for the 40 million people worldwide who are blind or have significant visual impairment. It’s reported that 65% of those with visual impairment and 82% of those who are blind are over 50 years of age. In a special issue of Investigative Ophthalmology & Visual Science (IOVS), ophthalmic leaders from around the world address “the aging eye” to focus attention on unmet needs and accelerate the translation of research findings into effective clinical care.
By sitting less and moving more, people can reduce their risks of chronic diseases and make aging easier, according to Kansas State University research.
Louis Medvene, Wichita State University professor of psychology and director of the Social Relationships Research Workgroup, is exploring the potential benefits of computer access to senior citizens' health.
Virtual reality, dance and fun are not the first things that come to mind when we think of treating urinary incontinence in senior women. However, these concepts were the foundations of a promising study .
Minority of panel members who disagree with raising systolic blood pressure targets for people over 60 years of age provide their evidence in a new commentary in the Annals of Internal Medicine.
Psychology researchers find parents set themselves up for speech errors when they give their children similar-sounding names.
Highly diverse cancers share one trait: the capacity for endless cell division. Unregulated growth is due in large part to the fact that tumor cells can rebuild protective ends of their chromosomes, which are made of repeated DNA sequences and proteins. Normally, cell division halts once these structures, called telomeres, wear down. But cancer cells keep on going by deploying one of two strategies to reconstruct telomeres.
Using high-resolution fMRI imaging in patients with Alzheimer's disease and in mouse models of the disease, researchers have clarified three fundamental issues about Alzheimer's: where it starts, why it starts there, and how it spreads. In addition to advancing understanding of Alzheimer's, the findings could improve early detection of the disease, when drugs may be most effective. The study was published today in the online edition of the journal Nature Neuroscience.
Most people with dementia who live at home have multiple unmet health and welfare needs, any number of which could jeopardize their ability to remain home for as long as they desire, new Johns Hopkins research suggests.
The study identifies a common, early marker of senescent cells that could have important implications for tumor suppression and aging-related diseases like Progeria
For the first time, researchers describe the effect of sleep deprivation on the unfolded protein response in peripheral tissue. Stress in pancreatic cells due to sleep deprivation may contribute to the loss or dysfunction of cells important to maintaining proper blood sugar levels, and that these functions may be exacerbated by normal aging. The combined effect of aging and sleep deprivation resulted in a loss of control of blood sugar, somewhat like pre-diabetes in mice.
A low level of daily exposure to a common component of sunlight can cause skin damage at the molecular level after just a few days, new research shows. The findings highlight the need for better sunscreens to protect against these damaging rays.
A recent paper by Mass. Eye and Ear/Harvard Medical School researchers in collaboration with researchers at the Ecole Normale Superieure, France, challenge the two dominant theories of how people localize sounds, explain why neuronal responses to sounds are so diverse and show how sound can be localized, even with the absence of one half of the brain. Their research is described on line in the journal eLife.
Mount Sinai researchers show that synaptic health in the brain is closely linked to cognitive decline. Further, they discover that estrogen restores synaptic health and also improves working memory.
Scientists at The Scripps Research Institute have discovered a natural mechanism that cells use to protect mitochondria, the tiny but essential “power plants” that provide chemical energy for cells throughout the body.
In their study, Sylvie Belleville and her team accurately predicted (at a rate of 90%) which of their research subjects with mild cognitive impairment would receive a clinical diagnosis of Alzheimer's disease within the following two years and which subjects would not develop this disease.
Sexually frustrated fruit flies lived shorter lives.
Improvements in education levels, health care and lifestyle credited for decline in dementia risk.
A year after a trauma injury, seniors had difficulty with daily tasks such as simple shopping trips.
As 10,000 baby boomers reach 65 each day, the incidence of cancer is increasing, estimated to increase by 67% between 2010 and 2030, bringing attention to the nation’s response to cancer care. Cancer is diagnosed at a higher rate, accounts for more survivors, and results in more deaths than in younger patients.
As we age, our body rhythms lose time before they finally stop. Breaking the body clock by genetically disrupting a core clock gene, Bmal1, in mice has long been known to accelerate aging , causing arthritis, hair loss, cataracts, and premature death. New research now reveals that the nerve cells of these mice with broken clocks show signs of deterioration before the externally visible signs of aging are apparent, raising the possibility of novel approaches to staving off or delaying neurodegeneration.
Dana Hayden, MD, Loyola colorectal surgeon, points out that 15 million women ages 40 and older (1 in 5) suffer from accidental bowel leakage. “Fecal incontinence is not a part of normal aging. It is a medical condition and there is treatment available,” says Hayden. “People with this condition become inhibited, stop socializing and do not even complete everyday routines such as grocery shopping or going to church because they fear an accident.” Loyola is one of the first medical institutions to offer a new outpatient procedure for fecal incontinence that often results in immediate improvement. In the new procedure, a gel is given through four injections into the wall of the anal canal.
Our epigenome is a set of chemical switches that turn parts of our genome off and on and are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle. The study provides a method to study sarcopenia, the degenerative loss of muscle mass that begins in middle age.
The progressive loss of skeletal muscle during aging, known as sarcopenia, underlies limitations in physical function and mobility, which in turn lead to falls, loss of independence, institutionalization and even death. Mayo Clinic researcher Nathan LeBrasseur, Ph.D., of Mayo Clinic’s Robert and Arlene Kogod Center on Aging and Department of Physical Medicine and Rehabilitation, presented an update on promising strategies and therapies to restore skeletal muscle health in the face of aging and disease during a symposium at the American Congress of Rehabilitation Medicine Annual Conference.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right